Clinical trials: sponsored by University Hospital, Antwerp
OSA
Evaluation of the Cardiovascular Effects of the MAS in the Treatment of Obstructive Sleep Apnea
In this prospective trial 50 patients, diagnosed with moderate to severe obstructive sleep apnea (OSA) (AHI > 15/h sleep) will be included and treated with mandibular advancement devices (MAD).
- Trial name
- NCT02320877
- Testing
- Mandibular Advancement Device (Somnomed Flex)
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Antwerp
Type 1 Diabetes, Insulin
The Use of Faster Acting Aspart in Type 1 Diabetes Patients
Data on switching from traditional mealtime insulins to fast-acting insulin aspart (Fiasp) in routine clinical practice are sparse.
- Conditions
- Type 1 Diabetes, Insulin, Time in Range
- Trial name
- NCT04711382
- Where
- Belgium
- Volunteers
- 438 people
- Sponsor
- University Hospital, Antwerp
Tinnitus
The Value of EMDR in the Treatment of Tinnitus
A prospective, randomized, controlled, clinical trial with blind evaluator that uses TRT and EMDR as a treatment for tinnitus.
- Trial name
- NCT03114878
- Testing
- TRT / EMDR, TRT / CBT
- Where
- Belgium
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Stroke, Ischemic
A Personalized, Digital Coaching Program After Stroke
The Belgian Stroke Council initiated a project to improve risk factor control and medication adherence in ischemic stroke patients by developing an individualized in-hospital initiated and post- discharge, digital coaching…
- Trial name
- STROKECOACH (NCT03038685)
- Testing
- Strokecoach.be - digital coaching program for stroke patients
- Where
- 4 sites in Belgium
- Volunteers
- 148 people
- Sponsor
- University Hospital, Antwerp
Hepatitis E
Morbidity and Mortality of Hepatitis E Virus Infections in Belgium
Hepatitis E Virus (HEV) infections are emerging in the Western world with a predominance of HEV genotype (gt) 3. Except for age older than 50 years, male gender, chronic liver disease and immunosuppressed status, no correlators…
- Trial name
- NCT04670419
- Testing
- Viral clade
- Volunteers
- 280 people
- Sponsor
- University Hospital, Antwerp
Diabetes Mellitus, Lipohypertrophy
Lipohypertrophy Monitoring Study
The investigators intend to audit the impact of optimal injection technique education delivered through a multimodal tailored approach augmented with a digital 'tailorable' patient learning platform on clinical parameters and…
- Conditions
- Diabetes Mellitus, Lipohypertrophy, Hypoglycemia
- Trial name
- LiMo (NCT04659330)
- Testing
- Online education (BdandMe) for injection technique, 4mm needles
- Where
- Belgium
- Volunteers
- 171 people
- Sponsor
- University Hospital, Antwerp
Keratoconus
Retrospective Digital Computer Analysis of Keratoconus Evolution - REDCAKE
The purpose of this study is to create a database of keratoconic eyes with two or more corneal topographies/tomographies, at least 5 months apart
- Trial name
- REDCAKE (NCT03235856)
- Where
- Belgium
- Volunteers
- 972 people
- Sponsor
- University Hospital, Antwerp
Hearing Loss
Evaluating the Revised WORQ in CI Users
The Work Related Questionnaire (WORQ) is a 59-item questionnaire of which each item represents an International Classification of Functioning and disability category.
- Trial name
- NCT04602780
- Where
- 5 sites in Australia, Belgium and 3 more
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Tinnitus, Subjective
HD-tDCS as a Treatment for Chronic Tinnitus
Transcranial Direct Current Stimulation (tDCS) aims to induce cortical plasticity by modulating the activity of brain structures.
- Trial name
- NCT04565132
- Testing
- High Definition transcranial Direct Current Stimulation
- Volunteers
- 117 people
- Sponsor
- University Hospital, Antwerp
Hearing Loss, Sensorineural, Bilateral Vestibulopathy
Effect of Hearing Loss and Vestibular Decline on Cognitive Function in Older Subjects
The world population has been growing and aging dramatically, with a rising prevalence of dementia. Worldwide, around 50 million people have dementia, with 10 million new cases added every year.
- Conditions
- Hearing Loss, Sensorineural, Bilateral Vestibulopathy, Alzheimer Disease, Mild Cognitive Impairment
- Trial name
- GECkO (NCT04385225)
- Testing
- Longitudinal follow-up
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Cystic Fibrosis
Functional Respiratory Imaging and Orkambi in CF
Open-label study to investigate the effects of Orkambi in CF patients homozygous for the F508del mutation by functional respiratory imaging.
- Trial name
- NCT03956589
- Testing
- Orkambi
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- University Hospital, Antwerp
Otitis Media With Effusion, Healthy
The URT and Middle Ear Microbiota in Health and During Chronic OME
This study analyses which bacteria are present in the middle ear space and adjacent upper respiratory tract niches in healthy people and in patients suffering from chronic otitis media with effusion (OME; glue ear).
- Trial name
- NCT03109496
- Testing
- Collection of body fluids/swabs
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- University Hospital, Antwerp
Microbiota Upper Respiratory Tract
Microbiota Upper Respiratory Tract
The aim of this study is to investigate whether the microbiota in the upper respiratory tract (URT) (nose, nasopharynx and sinuses) of chronic rhinosinusitis (CRS) patients is disturbed compared to healthy individuals.
- Trial name
- ProCure (NCT02933983)
- Testing
- no intervention, compare URT microbiome healthy control group-chronic rhinosinusitis patients
- Where
- Belgium
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Healthy Volunteers, Chronic Rhinosinusitis (Diagnosis)
Study of Probiotic Potential of Lactobacillus Strains in the Upper Respiratory Tract After Nasal Spray Application
Probiotics are defined as "live micro-organisms that, when administered in adequate amounts, confer a health benefit to the host" (Hill et al, 2014).
- Conditions
- Healthy Volunteers, Chronic Rhinosinusitis (Diagnosis), Probiotics, Sprays
- Trial name
- NCT03587545
- Testing
- Probiotic nasal spray
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Pain, Postoperative
Sublingual Sufentanil Tablet System (SSTS) Versus Intravenous Patient Controlled Analgesia After Back Surgery.
In this study, numeric rating scale (NRS) and side effects are measured after usage of a sublingual sufentanil tablet system (SSTS) in comparison to intravenous patient controlled analgesia (PCIA).
- Trial name
- NCT03036514
- Testing
- Sublingual sufentanil tablet system, Patient-controlled intravenous analgesia
- Where
- Belgium
- Volunteers
- 27 people
- Sponsor
- University Hospital, Antwerp
Toilet Training, Child, Preschool
Group Toilet Training of Healthy Children, in Daycare Centers (CRCT)
Evaluation of a new method of toilet training (TT), meaning TT in group in daycare centers, guided by a TT expert. Children are included based on signs of readiness for TT.
- Trial name
- NCT04221776
- Testing
- Group toilet training in daycare, Individual toilet training at home
- Where
- Belgium
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Postoperative Pain, Postoperative Nausea
Implementing a Postoperative MIRP (Minimally Invasive Repair of Pectus) Program Via Tele-monitoring
MIRP (Minimally Invasive Repair of Pectus) as surgical correction of pectus excavatum or carinatum is performed to achieve physiological, cosmetic, and psychological benefits for the patient.
- Trial name
- NCT03100669
- Testing
- Pectus surgery
- Where
- Belgium
- Volunteers
- 47 people
- Sponsor
- University Hospital, Antwerp
Breast Cancer, Mastectomy, Modified Radical
Comparison Between Levobupivacaine and Levobupivacaine With Dexmedetomidine in Ultrasound Guided Pectoral Nerve Block
A double blind prospective randomized controlled trial in which the effect of single shot levobupivacaine 0,25% will be compared with the effect of levobupivacaine 0.25% in association with dexmedetomidine when performing an…
- Trial name
- NCT03456661
- Testing
- Levobupivacaine, Levobupivacaine + Dexmedetomidine
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Antwerp
Pulmonary Ventilation
Flow Controlled Ventilation (FCV) With the Evone Ventilator and Tritube Versus Volume Controlled Ventilation (VCV)
The Evone® ventilator is a new device capable of lung ventilation through a narrow-bore cannula, the Tritube.Two ventilation modes are possible: high frequency jet ventilation (HFJV) and flow-controlled ventilation (FCV).
- Trial name
- NCT03873233
- Testing
- Aisys Carestation ventilator and normal endotracheal tube, Evone ventilator and Tritube
- Where
- Belgium
- Volunteers
- 8 people
- Sponsor
- University Hospital, Antwerp
Candidiasis, Vulvovaginal
Study of the Vaginal Microbiota and the Potential of a Vaginal Probiotic Cream in Vaginal Candidosis
This study evaluated the effect of a vaginal gel containing three live probiotic bacteria on vaginal Candida albicans infection in flemish patients (n=20).
- Trial name
- NCT03975569
- Testing
- Probiotic vaginal gel
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp