Clinical trials: sponsored by University Hospital, Bordeaux
Weaning From Mechanical Ventilation
Comparison of the Impact of Three Programs of Inspiratory Muscles.
Ventilator-induced diaphragmatic dysfunction appears to contribute to slow weaning from mechanical ventilation. Several trials of inspiratory muscle training to facilitate weaning in intensive care have been performed, with…
- Trial name
- PREDRIC (NCT02855619)
- Testing
- Martin, Cader, EDRIC
- Where
- 2 sites in France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Bordeaux
Benign Brain Tumor
Nausea Induced by Radiation of the Dorsal Vagal Complex for Benign Brain Tumors (NausiCAA)
Patients irradiated to the brain frequently experience nausea. The dorsal vagal complex (DVC) area is a specific brainstem zone and has been identified as likely responsible for nausea.
- Trial name
- NausiCAA (NCT06506578)
- Testing
- Radiation
- Where
- 3 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Bordeaux
Infective Endocarditis
Contribution of PET/CT With Gallium 68 Citrate (68Ga-PET/CT) for the Diagnosis of Prosthetic Valve Infective Endocarditis
CiGal-EI-TEP is an exploratory study that aim to assess the diagnostic performance of 68Ga Positron emission tomography (PET) / Computed Tomography (CT) for the diagnosis of prosthetic valve infective endocarditis in comparison…
- Trial name
- CiGal-EI-TEP (NCT05446376)
- Testing
- 68Ga-citrate PET/CT
- Where
- France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Bordeaux
Multiple Sclerosis
Emotional Processing, Family Life, Friendship and Social Integration in Patients With Multiple Sclerosis
In addition to the physical, cognitive and psychological symptoms experienced by individuals with Multiple Sclerosis (MS), there is new research which indicates that some individuals with MS have a deficit in emotional…
- Trial name
- EMOSOCIAL-MS (NCT02708927)
- Testing
- Clinical evaluation, Cognitive evaluation
- Where
- 2 sites in France
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Arthritis, Rheumatoid, Spondylitis, Ankylosing
Study of Gynecological Follow-up of Patients With Autoimmune Disease or Inflammatory Rheumatism
Autoimmune diseases are the consequence of an abnormality of the immune system, leading it to attack components of our own body. They have a wide variety of presentations.
- Conditions
- Arthritis, Rheumatoid, Spondylitis, Ankylosing, Lupus Erythematosus, Systemic, Scleroderma, Systemic
- Trial name
- MARIGYN (NCT05961267)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 318 people
- Sponsor
- University Hospital, Bordeaux
COPD (Chronic Obstructive Pulmonary Disease), Asthma (Diagnosis)
Creation of a Biological Collection of BRonchiaI and Pulmonary Tissues From Surgical wastE
The biological samples and associated data will facilitate the successful implementation of the research collaboration between Bordeaux University Hospital and the University of Bordeaux on the pathophysiology of bronchopulmonary…
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Asthma (Diagnosis), Safe Volunteers
- Trial name
- BRISE (NCT07780630)
- Testing
- Fiberscopic samples, Sputum, Nasal brushing
- Where
- France
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Stroke, Patient Education
Impact of a Nursing Educational Consultation on the Patient's Adherence to Their Post-stroke Care Plan.
This prospective, single-center, randomized study will evaluate the impact of implementing an educational nursing consultation at the end of hospitalisation for stroke patients returning home on overall adherence to…
- Trial name
- ICEIPAVC (NCT07524036)
- Testing
- nursing educational consultation
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Bordeaux
ANCA Associated Vasculitis
Soluble CD95 Ligand Role in the Pathophysiology of Antineutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis
The study aims at defining the role of soluble CD95 Ligand in the physiopathology of a rare group of inflammatory diseases: ANCA associated vasculitis.
- Trial name
- VASC-FAS (NCT03698071)
- Testing
- blood sample, urine sample
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Bordeaux
Lymphogranuloma Venereum, no Anorectal Symptoms
Multicentre Study Evaluating the Efficacy of a 7-day Course of Doxycycline for the Treatment of Asymptomatic Anal Lymphogranuloma Venereum.
Lymphogranuloma venereum (LGV) is a sexually transmitted infection (STI) caused by the L genotypes of C. trachomatis. Proctitis is the main clinical manifestation of infection in the current LGV epidemic.
- Conditions
- Lymphogranuloma Venereum, no Anorectal Symptoms, Doxycycline
- Trial name
- SHORT-LGV (NCT07767422)
- Testing
- Doxycline
- Where
- 14 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Bordeaux
Renal Cell Carcinoma
Identification and Description of Patients With High-risk Non Metastatic RCC
Renal cell carcinoma (RCC) is the 14th most common cancer worldwide. Surgery is the standard of care for localized RCC, however, the risk of recurrence varies widely among patients.
- Trial name
- HIROES (NCT07753343)
- Testing
- Cohort 1, Cohort 2, Cohort 3
- Where
- France
- Volunteers
- 6,109 people
- Sponsor
- University Hospital, Bordeaux
Glioblastoma
A Study to Better Understand the Biological and Molecular Mechanisms Involved in Glioblastoma Recurrence and Progression
BORDEAUX-GLIO is a prospective, monocentric study which will describe the molecular, immune and metabolic pathways involved in the progression and relapse of glioblastoma, using blood and tumor samples from patients who have…
- Trial name
- BORDEAUX-GLIO (NCT07173829)
- Testing
- samples
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Bordeaux
Diabetes Mellitus, Type 2
Evaluation of the Effectiveness of Extending the "Passerelle" System for Prescribing Adapted Physical Activity to Patients With Type 2 Diabetes in Nouvelle-AQUItaine (France)
Type 2 diabetes is on the increase worldwide. Two major risk factors have been identified: overweight and physical inactivity. National and international recommendations encourage general practitioner to guide patients in…
- Trial name
- PAPA-NAQUI (NCT06493955)
- Testing
- Adapted physical activity for 12 months, Adapted physical activity for 6 months
- Where
- France
- Volunteers
- 308 people
- Sponsor
- University Hospital, Bordeaux
Essential Tremor
Electroclinical Correlates in Essential Tremor
Essential tremor (ET) is a neurological disorder that affects nearly 0.9% of the world's population. High-frequency Deep Brain Stimulation (DBS) of the ventral-intermediate nuclei of the thalamus (VIM) has been proven as an…
- Trial name
- ECOLOVIM (NCT05671848)
- Testing
- Recordings of thalamic activity
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Bordeaux
Multiple Myeloma
Injection of ex Vivo Amplified G-CSF Mobilised Autologous Peripheral Blood Stem Cell Transplantation
Hematopoietic reconstitution defined by a neutrophils number > 500/mm3 at day 7 after injection of ex vivo amplified graft and by a platelets number > 20000/mm3, at day 15 after the injection of ex vivo amplified graft, without…
- Trial name
- Expansion (NCT00461955)
- Testing
- autologous peripheral blood stem cell transplantation, ex vivo amplified
- Where
- France
- Volunteers
- 13 people
- Sponsor
- University Hospital, Bordeaux
Anesthesia , Analgesia
Echo-guided Scalp Blocks and Incidence of Postoperative Pain in Scheduled Supratentorial Intracranial Surgery.
Up to 30% of patients undergoing intracranial surgery present moderate to severe pain. In this type of surgery, the restriction of the pharmacopoeia, which goes against the concept of multimodal analgesia, results in the…
- Trial name
- ULTRASCALP (NCT07149077)
- Testing
- Echo-guided scalp blocks, Classic anesthetic strategy
- Where
- France
- Volunteers
- 230 people
- Sponsor
- University Hospital, Bordeaux
Common Variable Immunodeficiency
Peripheral Helper T-cells in Common Variable ImmunoDeficiency
The aim is to determine whether whether Tph could support non-infectious complications through providing help to pathological B-cells.
- Trial name
- TAPDI (NCT07255157)
- Testing
- blood sample
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Multiple Sclerosis, Primary Progressive
Cognition Evolution and MRI Markers in PPMS Patients on 2 Years
Cognitive impairment is nowadays more and more recognized as an important feature of the multiple sclerosis (MS) disease. Cognitive disorders frequency in MS is estimated between 40 and 60%.
- Trial name
- PRO-COG (NCT03455582)
- Testing
- Clinical assessment, Ecological evaluation, Neuropsychological evaluation
- Where
- 3 sites in France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Atrial Fibrillation
Ground-Breaking Electroporation-based Intervention for PAROXysmal Atrial Fibrillation Treatment (BEAT PAROX-AF)
BEAT AF is a randomized controlled trial aiming to demonstrate that pulsed field energy is faster, more effective and safer (tissue selectivity) than RF for paroxysmal AF ablation
- Trial name
- BEAT PAROX-AF (NCT05159492)
- Testing
- PVI using PEF, PVI using CFRF
- Where
- 9 sites in Austria, Belgium and 3 more
- Volunteers
- 292 people
- Sponsor
- University Hospital, Bordeaux
Renal Cancer
Multiparametric MRI for Diagnosing Small Renal Tumors
Renal cell carcinoma represents annually 3-5% of all new cancer diagnoses. To date, the standard of care for small renal masses is partial nephrectomy.
- Trial name
- IRMK01 (NCT03470285)
- Testing
- Multiparametric MR imaging (mpMRI)
- Where
- 18 sites in France
- Volunteers
- 387 people
- Sponsor
- University Hospital, Bordeaux
Chronic Myeloid Leukaemia
Multicenter Trial Estimating the Persistence of Molecular Remission in Chronic Myeloid Leukaemia in Long Term After Stopping Imatinib
Background: Complete molecular remission under imatinib, therapeutic interruption possible for patients in complete remission proved in different trials.
- Trial name
- STIM 2 (NCT01343173)
- Testing
- Imatinib stop
- Where
- 32 sites in France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Bordeaux