Clinical trials: sponsored by University Hospital, Brest
Patients in Complex Situations
A Quality Rating Scale for Patients in Complex Situations
The prevalence of multimorbid patients and complex care is increasing in France and elsewhere in the world. It concerns 60% of the over 65 years old.
- Trial name
- Qualsoprim_2 (NCT03886285)
- Testing
- Questionnaire
- Where
- 12 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Brest
Prostate Cancer
Inter-observer Variability in the Segmentation of Prostate Tumour Lesions Using Multiparametric MRI (VARIOP)
Following the major technological and scientific advances in external radiotherapy in recent decades, thanks to the use of three-dimensional conformal techniques combined with intensity modulation, image-guided radiotherapy has…
- Trial name
- VARIOP (NCT05996289)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Brest
Polymyalgia Rheumatica
Immunopathology of Polymyalgia Rheumatica on Shoulder Bursae's Biopsies
The work carried out at the Brest University Hospital on serum immunological changes in patients with polymyalgia rheumatica (PMR) (based on clinical protocols TENOR, SEMAPHORE, THEN) made it possible to describe the changes in…
- Trial name
- BAOBAB (NCT04727879)
- Testing
- Synovial membrane biopsy with puncture of synovial fluid, Joint fluid sampling, Blood sample
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Brest
Oncologic Complications, Anemia
Liberal Versus Restrictive Transfusion Threshold in Oncologic surgerY
Anemia is common in oncology. Up to three-quarters of cancer patients are exposed to an episode of anemia. In oncology surgery, perioperative bleeding is a major risk factor for anemia.
- Trial name
- LIBERTY1 (NCT04506125)
- Testing
- Haemoglobin 9.5 g/dL, Haemoglobine 7.5g/dL
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Patients in Complex Situations
Establish an Evaluation Scale for the Quality of Primary Care in Multi-professional Health Centres and Homes Integrating the Point of View of Patients in Complex Care Situations and Their Caregivers.
The prevalence of multimorbid patients and complex care is increasing in France and elsewhere in the world. It concerns 60% of the over 65 years old.
- Trial name
- Qualsoprim_3 (NCT05057520)
- Testing
- Questionnaire
- Where
- 5 sites in France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Brest
Bladder Cancer
Professional Bladder Cancers and the Profession of Painter
This is a retrospective study on bladder cancer in French painters' population. The French agency ANSES collected data from all occupational and environmental diseases center in a specific database called RNV3P.
- Trial name
- NEVPP (NCT05937555)
- Where
- 6 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Brest
Blood Pressure
Comparison of 3 Techniques for Blood Pressure Measurements During Interventional Neuroradiology Procedures
Some observational studies demonstrated that hypotension was associated with post-operative morbidity. During neuroradiological procedures, cerebral perfusion pressure should be cautiously maintained and hypertension should also…
- Trial name
- NEXFIN-NRI (NCT05283824)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Brest
Postpartum Hemorrhage, Venous Thromboembolism
Haemorrhages and Thromboembolic Venous Disease of the Postpartum
The aim of this study is to evaluate the frequencey and the determinants of postpartum major complications (hemorrhage and thrombosis) up to 3 months after delivery in the maternity hospitals of Finistère (Bretagne - France)
- Trial name
- HEMOTHEPP (NCT02443610)
- Where
- 6 sites in France
- Volunteers
- 20,241 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Cerebral (CVAs), Ischemic Cerebrovascular Accident
Population-based Brest Stroke Registry
The registry is the main objective exhaustive list of cases validated stroke brain on a geographical area defined to calculate an incidence.
- Conditions
- Cerebral (CVAs), Ischemic Cerebrovascular Accident, Stroke, Brain Ischemia
- Trial name
- BREST (NCT02900521)
- Where
- France
- Volunteers
- 15,000 people
- Sponsor
- University Hospital, Brest
Pelvic Fracture
Use of Laparoscopy in the Treatment of Pelvic Ring Ruptures
Case series to describe the use of laparoscopy for the treatment of pelvic ring disruption.
- Trial name
- PELVICOELIO (NCT05836727)
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Brest
Advance Directives, Post Intensive Care Syndrome
Post-ICU Consultation : a Time to Discuss Advance Directives (CoPRADA)
The aim of this study is to assess the possibility of discussing advance directives during post-intensive care consultation.
- Conditions
- Advance Directives, Post Intensive Care Syndrome, Advance Care Planning
- Trial name
- CoPRADA (NCT05817500)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Brest
Colorectal Cancer
General Practitioners and Participation Rate in ColoRectal Cancer Screening
Colorectal cancer is the 2nd leading cause of cancer mortality in France. However this cancer is preventable in the majority of cases by early detection of adenomas.
- Trial name
- AMDepCCR (NCT04492215)
- Testing
- Interaction between patient and trained general practitioners in motivational interviewing
- Where
- 53 sites in France
- Volunteers
- 902 people
- Sponsor
- University Hospital, Brest
Flexor Digitorum Longus on the Right, Flexor Digitorum Longus on the Left
Evaluation of the Mobility of the Digital Flexor Tendons
To study flexor tendon excursion in the hand after surgery by dynamic MRI
- Conditions
- Flexor Digitorum Longus on the Right, Flexor Digitorum Longus on the Left, Tendon Rupture, Tendon Injury - Hand
- Trial name
- DynamicMRI (NCT03823755)
- Where
- 3 sites in France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Brest
Preeclampsia
Validation of the French Translation of a Self-questionnaire Looking for a History of Pre-eclampsia.
PRERETRO is a study for validation of the French translation of a self-questionnaire looking for a history of pre-eclampsia of more than 5 years in women who have already had a pregnancy of more than 6 months with childbirth at…
- Trial name
- PRERETRO (NCT04658966)
- Testing
- administration of a self-questionnaire
- Where
- France
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Systemic Sclerosis, Preeclampsia
Is a History of Pre-eclampsia a Risk Factor for Vascular Phenotype in Women With Systemic Sclerosis?
Background: Pre-eclampsia, defined by the association of an arterial hypertension and significant proteinuria after 20 weeks of gestation, complicates 1 to 2% of pregnancies in France.
- Conditions
- Systemic Sclerosis, Preeclampsia, Vascular Complications
- Trial name
- PREVASCLERO (NCT04363021)
- Where
- 10 sites in France
- Volunteers
- 378 people
- Sponsor
- University Hospital, Brest
Congenital Hip Dislocation
Research for Genetic Factors Involved in Congenital Dislocation of Hip: Genome-wide Association Study in Grand West France
The main objective is to identify the genes involved in congenital dislocation of the hip. The secondary objectives are to measure the association between mechanical risk factors and congenital dislocation of hip and study the…
- Trial name
- GENETHIP (NCT02900482)
- Testing
- Sampling saliva
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Brest
Healthy Volunteers, Pathologies for Which paCO2 Monitoring is Crucial, Particularly in the Context of Chronic Obstructive Pulmonary Disease (COPD)
Influence of Temperature on Transcutaneous Blood Gas Diffusion: CAPNOS Project
The measurement of tcpCO2 has many disadvantages: the need for regular calibration (4 to 8 hours) of the sensor, the fact that the sensor heats the skin (risk of burns), the impossibility of measurement in ambulatory and the high…
- Trial name
- CAPNOS (NCT05637138)
- Testing
- tcpCO2 measure, tcpO2 measure, measurement of tissue conductivity to CO2: KS
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Cerebral Palsy Infantile
Study of the Sensitivity to Change of a Bimanual 3D Analysis Protocol for the Assessment of Upper Limb Movement in Children With Cerebral Palsy Before and After Therapies
Cerebral Palsy is the most common cause of motor disability in children. It can lead to a deficit of the upper limb which alters the realization of daily activities, in particular in bimanual situations, and eventually leads to a…
- Trial name
- BE API CHANGE (NCT05691556)
- Testing
- HABIT ILE rehabilitation course, botulinum toxin injections
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Brest
Cystic Fibrosis, Acute Respiratory Infection
Molecular Diagnosis of Respiratory Viral Infections on Sputum From Cystic Fibrosis Patients
The main objective of this project is to evaluate the agreement between nasopharyngeal and sputum specimens in terms of detection of viral infection in Cystic Fibrosis (CF) participants.This is a 12-month national, multicenter…
- Trial name
- MUCOVIR (NCT03736096)
- Where
- 11 sites in France
- Volunteers
- 115 people
- Sponsor
- University Hospital, Brest
Anti-epileptic Prophylaxis in Intracranial Neurosurgery
Comitial Prophylaxis in Neurosurgery in Patients Who Have Undergone Intracranial Surgery Programmed Supratentorial Surgery (Exeresis or Biopsy) Between 2019 and 2022
JUSTIFICATION Anti-epileptic prophylaxis has long been a systematic practice for supra-tentorial intracranial surgeries. Since 2021, European guidelines no longer recommend this prophylaxis and practices have evolved.
- Trial name
- PRO-CON (NCT05670860)
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University Hospital, Brest