Clinical trials: sponsored by University Hospital, Geneva
Nightshift Work, Handoff Sessions
Clinical Activity During Night-shift: an Ecological Study
A convenient sample of internal medicine residents will be observed during their nightshift work in the wards of the department of internal medicine of a university hospital.
- Conditions
- Nightshift Work, Handoff Sessions, Stress, Psychological, Regret
- Trial name
- NCT04123015
- Where
- Switzerland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Diabetic Foot
Less Infections for the Diabetic Foot
This is a randomized, unblinded, single-centre study. After eventual surgical debridement (not amputation), patients will be randomized to receive 1 of 2 targeted antibiotic regimens, in the ratio 1:1.
- Trial name
- NCT03615807
- Testing
- Surgical debridement (if needed), Microbiological sampling, Revascularisation (if needed).
- Where
- Switzerland
- Volunteers
- 182 people
- Sponsor
- University Hospital, Geneva
Acute Heart Failure
Investigating Reduction of aCute heArt Failure Readmission With Lung UltraSound-preliminary Trial
In Switzerland 15% of discharged patients are readmitted within 30 days. Acute heart failure is the leading cause of hospital admission and one of the most frequent reasons for re-admission, mainly because of congestion-driven…
- Trial name
- Pre-IcarUS (NCT04174794)
- Testing
- Lung ultrasound
- Where
- Switzerland
- Volunteers
- 43 people
- Sponsor
- University Hospital, Geneva
Prostate Cancer
ONE-SHOT Trial - Ultra-hypofractionated Single-dose SBRT for Prostate Cancer
The main objective of the phase I/II trial is to determine the safety and efficacy of a single fraction SBRT at a dose of 19 Gy in patients with localized prostate cancer.
- Trial name
- NCT03294889
- Testing
- Stereotactic body radition (SBRT)
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- University Hospital, Geneva
Coronavirus Infection, Sars-CoV2
Outcomes in Hospitalized Older Patients With COVID-19
In December 2019, the first patients infected with the 2019 novel coronavirus (2019-nCoV) were diagnosed in Wuhan. The clinical presentation and course of Severe Acute Respiratory Syndrome-CoV-2 (SARS-CoV-2) infection is poorly…
- Conditions
- Coronavirus Infection, Sars-CoV2, Elderly Infection, Old Age; Debility
- Trial name
- NCT04385212
- Where
- Switzerland
- Volunteers
- 230 people
- Sponsor
- University Hospital, Geneva
Acute Coronary Syndrome
Multi-dimensional Prevention Program After Acute Coronary Syndrome (ELIPS) (SPUM-ACS- SP1)
To demonstrate the effectiveness of the ELIPS programme (Multi-dimEnsionaL preventIon Program after Acute coronary Syndrome), which aims at improving quality of care of patients admitted to hospital with Acute Coronary Syndrome…
- Trial name
- NCT01075867
- Where
- 4 sites in Switzerland
- Volunteers
- 2,498 people
- Sponsor
- University Hospital, Geneva
Congenital Lung Malformation, Congenital Lung Cyst
Congenital Lung Anomalies (CLA) Swiss Database
Congenital lung anomalies include different pathologies such as congenital cystic adenomatoid malformation, pulmonary sequestration, bronchial atresia, emphysema, bronchogenic cyst.
- Conditions
- Congenital Lung Malformation, Congenital Lung Cyst, Sequestrum, Bronchogenic Cancer
- Trial name
- CLADatabase (NCT03044769)
- Testing
- Malformations resection
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Geneva
Breast Neoplasms, Venous Thromboembolism
Hemostatic Profiles of Endocrine Therapies for Breast Cancer
The aim of this prospective cohort study is to evaluate the modifications of the biological hemostatic profile associated with the use of endocrine therapy in women with breast cancer (tamoxifen or aromatase inhibitors).
- Trial name
- HEMOBREAST (NCT03381963)
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Geneva
Musculoskeletal Diseases or Conditions, Rehabilitation
REACH Personal Mobility Device Testing
Developed countries are facing the challenge of ageing societies, lack of infrastructure for healthcare and high cost of care. Researchers have been attempting to answer these problems by using innovative technology to promote…
- Trial name
- REACH (NCT03847454)
- Testing
- REACH, Standard of care
- Where
- Switzerland
- Volunteers
- 57 people
- Sponsor
- University Hospital, Geneva
Amyotrophic Lateral Sclerosis 11
Chewing Efficiency Measured by a Two Colour Chewing Gum Test in Amyotrophic Lateral Sclerosis (ALS) Patients?
Study aims: The primary aim is to determine whether chewing efficiency, determined by a two-colour mixing ability test, and maximum bite and lip force decrease in ALS patients.
- Trial name
- NCT01772888
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Colitis
Determination of the Aetiologies of Acute Colitis and Early Identification of Patients Requiring Diagnostic Colonoscopy
The aetiologies of computed tomography-diagnosed acute colitis remain surprisingly unknown. Moreover, no diagnostic tool or clinical score allow to quickly determine or at least stratify the exact cause of colitis in patients…
- Trial name
- NCT02709213
- Testing
- Diagnostic
- Where
- Switzerland
- Volunteers
- 182 people
- Sponsor
- University Hospital, Geneva
Perineal Tear, Pain
The Application of Honey on Perineal Sutures
Evaluate the effect of honey on perineal tears or episiotomies pain associated or not with anterior vulvar tears after vaginal delivery.
- Conditions
- Perineal Tear, Pain, Burns
- Trial name
- NCT03670420
- Testing
- Medical honey
- Where
- Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Postoperative Nausea and Vomiting, Vomiting
Dexamethasone for the Treatment of Established Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) are frequent after surgery and anaesthesia. Dexamethasone is widely used as antiemetic for the prevention of PONV.
- Trial name
- DexPonv (NCT01975727)
- Testing
- Dexamethasone 3 mg, Dexamethasone 6 mg, Dexamethasone 12 mg
- Where
- 4 sites in Switzerland
- Volunteers
- 256 people
- Sponsor
- University Hospital, Geneva
Olecranon Bursitis, Patellar Bursitis
Optimisation of the Treatment of Infectious Bursitis
The study investigates prospectively the cost-savings related to a one-stage bursectomy (debridement, drainage and closure at the same time) versus two-stage bursectomy (debridement, left open and closure at a second time) of…
- Trial name
- NCT01406652
- Testing
- Two-stage bursectomy
- Where
- Switzerland
- Volunteers
- 224 people
- Sponsor
- University Hospital, Geneva
Diabetic Foot Ulcer
Efficacy and Safety of Garamycin® Sponge in Diabetic Patients With a Moderate or Severe Foot Ulcer Infection
The purpose of this study is to determine whether Garamycin Sponge (Gentamicin-Collagen sponge) in combination with antibiotics is safe and effective in treating moderate and severe diabetic foot infections.
- Trial name
- NCT01951768
- Testing
- Garamycin Sponge (Gentamicin-Collagen sponge), Systemic Antibiotic
- Where
- Switzerland
- Volunteers
- 88 people
- Sponsor
- University Hospital, Geneva
Stroke
Mirror Therapy: Effects on Functional Recuperation of Severe Upper Limb Paresis After Stroke
After stroke, patients frequently suffer from arm or hand weakness. There are numerous rehabilitation methods to stimulate recovery, amongst which mirror therapy (MT).
- Trial name
- MT (NCT02949609)
- Testing
- Mirror Therapy, Control Therapy
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- University Hospital, Geneva
Critical Illness
The ICALIC Accuracy Validation in Geneva Study
This study aims at validating the accuracy of the new indirect calorimeter (Q-NRG, COSMED, Italy), developed for the ICALIC multicenter study. The validation of accuracy will only be conducted in Geneva center.
- Trial name
- ICALIC (NCT02790697)
- Testing
- Indirect calorimetry
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Hospital, Geneva
HPV-Related Cervical Carcinoma
Knowledge and Attitudes Towards Human Papillomavirus Infections and HPV Vaccination
A better understanding of the target audiences about HPV infection and HPV vaccination would surely allow for a better spread of this vaccination in Switzerland.
- Trial name
- NCT03888599
- Testing
- knowledge questioannaire
- Where
- Switzerland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Ambulatory Surgical Procedures, Anxiety Disorders
Educational Video and Peri-operative Anxiety
Preoperative anxiety is a common problem with an impact on surgical outcome, anaesthetic drug dosage and patient's satisfaction. An important component of preoperative anxiety is due to concerns related to anaesthesia.
- Trial name
- NCT03581097
- Testing
- Video Group
- Where
- Switzerland
- Volunteers
- 93 people
- Sponsor
- University Hospital, Geneva
Complication, Postoperative
Perioperative Fluid Management: Goal-directed Versus Restrictive Strategy
There is no ideal "cookbook recipe" for fluid prescription that would fit every surgical patient. In this study, the investigators working hypothesis is that the adoption of an integrative algorithm for perioperative fluid and…
- Trial name
- NCT02625701
- Testing
- Goal-directed therapy, Restrictive fluid therapy
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Geneva