Clinical trials: sponsored by University Hospital, Geneva
Food Allergy, Peanut Allergy
Study to Assess Tolerance of Traces in Peanut/Tree Nut Allergic Children.
This protocol will help better define whether patients with peanut and/or tree nut food allergy can tolerate traces in products with precautionary allergen labelling.
- Conditions
- Food Allergy, Peanut Allergy, Tree Nut Allergy
- Trial name
- NCT03680066
- Testing
- Oral food challenge to foods with traces
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Neurosyphilis
Value of an Intrathecal Synthesis Index of Specific Antitreponema IgG for Neurosyphilis Diagnosis
A retro-prospective case-control Swiss study was conducted to evaluate the diagnostic performance of measuring an antibody index (AI) for intrathecal synthesis of specific anti-Treponema pallidum (T.
- Trial name
- NCT06152393
- Testing
- Measure of an antibody index for intrathecal synthesis of specific anti-Treponema pallidum IgG by ELISA.
- Where
- Switzerland
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Impostor Phenomenon, Imposter Syndrome
Impostor Syndrome and Burnout in Swiss Residents and Chief Residents Anaesthesiologists
Surveys including a demographic chart, the Clance Impostor phenomenon scale (CIPS) and the Malash burnout inventory for medical personnel (MBI-HSS-MP) will be sent to residents and chief-residents in anesthesiology in Latin…
- Conditions
- Impostor Phenomenon, Imposter Syndrome, Burnout, Professional, Burnout, Student
- Trial name
- NCT06097325
- Testing
- Clance impostor phenomenon scale, Maslach Burnout Inventory for Medical Professional
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Geneva
Attention Deficit Disorder With Hyperactivity
Effects of a Novel Neurofeedback Protocol on ADHD Subcomponents
Mounting evidence suggests that closed-loop brain-training, commonly known as neurofeedback (NFB), may represent a new therapeutic opportunity for patients with Attentional Deficit/Hyperactivity Disorder (ADHD), which manifests…
- Trial name
- NFB@HOME (NCT04408521)
- Testing
- NEUROFEEDBACK, CONTROL
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- University Hospital, Geneva
Coronary Artery Disease, Acute Coronary Syndrome
BIOSTEMI Extended Survival
The objective of the BIOSTEMI ES study is to assess the long-term clinical outcomes with the Orsiro ultrathin-strut biodegradable polymer sirolimus-eluting stent compared to the Xience thin-strut durable polymer…
- Trial name
- BIOSTEMI ES (NCT05484310)
- Where
- 10 sites in Switzerland
- Volunteers
- 1,300 people
- Sponsor
- University Hospital, Geneva
Impaired Oxygen Delivery, Critically Ill Patient
Non-Invasive Measurement of SjvO2 Using Near Infrared Spectroscopy in Critically Ill Patients
ScvO2 is an important parameter in the management of critically ill patient. The only way to measure it is to have an internal jugular or subclavian central venous catheter.
- Trial name
- NIRS-SCJVO2 (NCT04624009)
- Where
- 2 sites in Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Hypothermia, Accidental, Defibrillation
Defibrillation in Accidental Hypothermia
Hypothermia (core temperature ≤35°C) is a frequent and life-threatening complication after mountain accidents, near-drowning, and intoxications, and can provoke arrhythmia, reduced cardiac contractility, and cardiac arrest.
- Trial name
- NCT06131892
- Testing
- Defibrillation
- Where
- Switzerland
- Volunteers
- 63 people
- Sponsor
- University Hospital, Geneva
Premature Birth, Cerebral Palsy
Neuro-biomechanical Determinants for Motor Behavior in High-risk Infants
This project focuses on motor development, muscle growth and muscle activity. Using advanced, instrumented tests such as , the link between muscles and the movement characteristics will be studied.
- Conditions
- Premature Birth, Cerebral Palsy, Neurodevelopmental Disorders, Brain Injuries
- Trial name
- BAMBI (NCT06111898)
- Testing
- No Intervention
- Where
- Switzerland
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Intra Cerebral Hypertension, Lactate Sodium Solution
Sodium Lactate Versus Hypertonic Saline Solution in the Treatment of Intracranial Hypertensive Episodes in Severe Brain Injured Patients
Brain oedema is a major complication of brain injury (TBI). It increases the risk of intracranial hypertension (ICH) and brain hypoxia, leading to an increase in mortality and poor neurologic outcome.
- Trial name
- SLHYSS (NCT06110429)
- Testing
- Lactate, Sodium, Hypertonic saline
- Volunteers
- 52 people
- Sponsor
- University Hospital, Geneva
Iron Induced Hypophosphatemia
Newborn Phosphocalcic Metabolism After Intravenous Iron Administration During Pregnancy
Iron deficiency anemia (IDA) is a very common health problem during pregnancy and intravenous (IV) iron substitution has become part of routine management.
- Trial name
- NCT06108258
- Testing
- IV iron administration
- Where
- Switzerland
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Ventilation, Lung Function
Respiratory Effects of Flow-Controlled Ventilation and Jet Ventilation in Patients Undergoing Laryngotracheal Surgery
Laryngotracheal surgery often requires a small diameter endotracheal tube to oxygenate patients under general anesthesia. Oxygenation is often only possible with high-frequency jet ventilators due to the use of small diameter and…
- Conditions
- Ventilation, Lung Function, Anesthesia, General
- Trial name
- Flowjet (NCT06063798)
- Testing
- General anesthesia for laryngotracheal surgery, Mechanical ventilation by FCV, Mechanical ventilation by HFJV
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University Hospital, Geneva
Incisional Hernia
Reducing the Incidence of Incisional Hernia After Stoma Closure Using a Prophylactic Mesh
Background: Preliminary studies have shown that application of a prophylactic mesh during stoma closure reduces the incidence of incisional hernia at site of stoma closure.
- Trial name
- PROMESH (NCT04510558)
- Testing
- Stoma closure with non-resorbable mesh (ULTRAPRO Advanced Mesh, Ethicon, Johnson & Johnson) in the sublay position, Stoma closure without mesh
- Where
- Switzerland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Food Allergy, Peanut Allergy
Pilot Study on Immunotherapy for the Treatment of Persistant Peanut Allergy
The purpose of this trial is to assess the safety and efficacy of peanut immunotherapy in children and adults with peanut allergy. Participants will receive immunotherapy with peanut every 2 weeks for a period of 3 months.
- Trial name
- NCT04974970
- Testing
- Peanut Immunotherapy
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- University Hospital, Geneva
Workflow, Time
Performance of Acquisition Automation of Cardiac MRI
For this study, cardiac MRI examinations performed will be prospectively included and realized either fully automatically or by a specialized radiology technician.
- Trial name
- NCT06012890
- Testing
- Automation of cardiac MRI acquisition
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Congenital Syphilis
Congenital Syphilis in Switzerland
A retrospective national epidemiological Swiss study was conducted to establish a real prevalence and description of congenital syphilis, and to better classify the reported congenital syphilis.
- Trial name
- NCT05975502
- Testing
- Epidemiological study
- Where
- Switzerland
- Volunteers
- 265 people
- Sponsor
- University Hospital, Geneva
Deafness, Hearing Loss
Benefits of Tablet-based Serious Games to Promote Speech Production in Young Children With Hearing Disabilities
Learning to speak is a major challenge for children with hearing impairments. Nowadays, special devices such as conventional hearing aids, bone-anchored hearing aids (BAHA) or cochlear implants (CI) allow successful…
- Trial name
- FunSpeech (NCT04454255)
- Testing
- FunSpeech, Control
- Where
- Switzerland
- Volunteers
- 13 people
- Sponsor
- University Hospital, Geneva
Premature Birth
Assessment of the Behavior of the Preterm Newborns
The project presented here aims to evaluate the discrimination capacity of the Observation of Sensory-Motor Behavior (OSMB) grid of the preterm infant, as well as its predictive capacity for the child's later psychomotor…
- Trial name
- GOCSM (NCT05898295)
- Testing
- no intervention
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Geneva
Back Pain, Low
Can we Improve Care Pathway in Low Back Pain?
The general objective of this pilot study is to investigate a new multi-level intervention in primary care to improve the care of patients with low back pain.
- Trial name
- DeltaDos (NCT05768516)
- Testing
- Implementation of best practice for low back pain in primary care
- Where
- 2 sites in Switzerland
- Volunteers
- 124 people
- Sponsor
- University Hospital, Geneva
Open Angle Glaucoma
Prospective, Open Label Study to Assess 24hs IOP Recorded With Triggerfish® in Patients With OAG Before and After DSCI
A prospective, open label study to assess the 24-hour intraocular pressure pattern recorded with SENSIMED Triggerfish® in patients with open angle glaucoma before and after deep sclerectomy with collagen implant
- Trial name
- NCT05876936
- Testing
- contact lens sensor (CLS) SENSIMED Triggerfish®
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- University Hospital, Geneva
Venous Thromboembolism
Postpartum Heparin Against Venous Thromboembolism: a Pilot Randomized Controlled Trial
In previous attemps to answer the question of risk-benefit of postpartum thromboprophylaxis, researchers were faced with low recruitement rates.
- Trial name
- PP-HEP (NCT05878899)
- Testing
- Enoxaparin
- Where
- Switzerland
- Volunteers
- 77 people
- Sponsor
- University Hospital, Geneva