Clinical trials: sponsored by University Hospital, Lille
Erythematotelangiectatic Rosacea
Evaluation of the New Laser PHOTOLASE PLV-585nm for the Treatment of Rosacea
Rosacea is a frequent dermatological condition, with a chronic and disturbing evolution that is characterized by redness, permanent erythema associated with telangiectasia (visible and permanent dilatation of the small vessels).
- Trial name
- ROSAPHOTOLASE (NCT03708263)
- Testing
- Excel V 532nm (KTP) green Laser, PHOTOLASE PLV 585 nm yellow laser
- Where
- France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Lille
Assisted Reproduction
Experience of Lock Down Related to the Covid-19 Epidemic and Its Impact on the Project of Parenthood
Observational, descriptive, cross-sectional, monocentric study, This Study is proposed to all couples followed in Assisted Reproduction and CECOS Nord for whom the protocols were stopped when they entered into confinement related…
- Trial name
- CONFIN-AMP (NCT04556630)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Lille
Chronic Low Back Pain
Alleviating Trunk Low Back Pain, With an Active Medical Device Study (ATLAS)
The aim of the study is to evaluate the reduction of pain by wearing the ATLAS Medical Device in standardized daily activities for patients with Chronic Low Back Pain.
- Trial name
- ATLAS (NCT03801941)
- Testing
- wearing ATLAS device during evaluation at 4th day, wearing ATLAS device during evaluation at 5th day
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Lille
Sars-CoV2, Rheumatoid Arthritis
Morbimortality of Covid-19 in Patients With Chronic Inflammatory Rheumatism Treated With Immunosuppressants
A retrospective monocentric study with large active files of patients monitored for rheumatoid arthritis, spondyloarthritis and systemic lupus erythematosus with as main endpoint the morbimortality of Covid-19 in these patients…
- Conditions
- Sars-CoV2, Rheumatoid Arthritis, Rheumatic Diseases
- Trial name
- CORhum (NCT04426279)
- Testing
- questionnaire assesment
- Where
- France
- Volunteers
- 539 people
- Sponsor
- University Hospital, Lille
Cystic Fibrosis
Evaluation of Short Antibiotic Combination Courses Followed by Aerosols in Cystic Fibrosis
The aim of this study is to investigate the efficacy of antibiotic therapy with any antibiotic (IV) and IV (Nebcin®) tobramycin for 5 days followed by Solution for nebuliser inhalation (Tobi®) for 9 days and antibiotic cures…
- Trial name
- TOBRAMUC (NCT03066453)
- Testing
- Tobi Inhalant Product, Nebcin
- Where
- 7 sites in France
- Volunteers
- 23 people
- Sponsor
- University Hospital, Lille
Surgery, Emergencies
Surgical Emergency Flows and Delays in Admission to the Operating Room
French hospitals treat non-elective surgery according to three organizational models: in a dedicated multi-specialty emergency operative room (OR), in a dedicated OR within a specialized surgical platform or in any available OR…
- Conditions
- Surgery, Emergencies, Postoperative Complications
- Trial name
- ACUTE-FLOW (NCT04585529)
- Where
- 10 sites in France
- Volunteers
- 1,149 people
- Sponsor
- University Hospital, Lille
Gynecologic Surgeries
Laparoscopic Surgery: Comparison of Conventional Trocars to the Teleflex® MiniLap® System
During laparoscopy, trocars are essential: they allow the passage of instruments through the wall. In gynecology, with exception, trocars 5mm (used for the passage of endo-scissors and forceps) and 10 to 12mm are used (especially…
- Trial name
- MiniTroc (NCT03726203)
- Testing
- laparoscopic gynecologic surgery with the MiniLap System., laparoscopic gynecologic surgery with the conventional single-use trocars.
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Lille
Idiopathic Cervical Dystonia
Targeting Methods of Botulinum Toxin Injections for Cervical Dystonia
Botulinum toxin injections are the treatment of choice for cervical dystonia. Even if this treatment is successful for most of the patients, partials or completes failures still remained.
- Trial name
- RINOCERAUS (NCT03946046)
- Testing
- Clinical targeting, Ultrasonography targeting
- Where
- France
- Volunteers
- 132 people
- Sponsor
- University Hospital, Lille
Sars-CoV2
Prevalence of COVID-19 Infection Among HCW in a French University Hospital
The objective of this study is to determine the prevalence of SARS-Cov2 infection among health care workers exposed of Lille University Hospital, to describe its evolution during the epidemic taking into account the influence of…
- Trial name
- EXPOCOVIA (NCT04371692)
- Testing
- self-administered questionnaire, SARS-Cov2 testing
- Where
- France
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Dumping Syndrome
Impact of an Educational Personalized Clinical Support Device Preventive and a Referent Nurse in Surgery for Obesity
The postprandial dumping syndrome is a frequent consequence of Roux-en-Y Gastric ByPass due to the rapid emptying of the stomach remnant in to the intestinal lumen.
- Trial name
- IRCO (NCT02891330)
- Testing
- Dietary and nutritional recommendations conducted by a nurse
- Where
- 4 sites in France
- Volunteers
- 135 people
- Sponsor
- University Hospital, Lille
Hemodynamic, Monitoring, Anesthesia
Pulse CONtour and BIoimpedance for Measurements of Stroke Volume During Changes in CARdiac Preload
Fluid therapy guided by stroke volume response to repeated fluid challenges is used for hemodynamic optimization during general anesthesia.
- Conditions
- Hemodynamic, Monitoring, Anesthesia, Blood Pressure
- Trial name
- ConBi-Car (NCT04231656)
- Testing
- CLEARSIGHT and NICCOMO measurements in sequence A, CLEARSIGHT and NICCOMO measurements in sequence B
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille
Limb Deficiencies
Early Prosthetics in Children With Upper Limb Deficiency
For children with congenital upper limb deficiency, introduction of the prosthesis is guided by clinical experience rather than by Evidence Based Medicine.
- Trial name
- EARLIMB (NCT04851600)
- Testing
- prosthesis
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille
Invasive Candidiasis, Candidemia
Genetic Susceptibility Factors for Candidemia.
This is a prospective case-control physiopathological study, which main objective is to determine the genetic host factors predisposing to candidemia.
- Conditions
- Invasive Candidiasis, Candidemia, Genetic Predisposition to Disease
- Trial name
- NCT02841501
- Testing
- Analysis of genetic polymorphisms
- Where
- France
- Volunteers
- 453 people
- Sponsor
- University Hospital, Lille
SARS-CoV 2
Association Between BMI and COVID-19
This study will involve collection of pseudonymized data from hospital-based data reporting at multiple international sites. Collating data from a large volume of patients with COVID-19 admitted in ICU across multiple…
- Trial name
- BMI-SARS-CoV-2 (NCT04391738)
- Testing
- Patients admitted to Intensive Care Unit with SARS-CoV2
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Lille
Alzheimer Disease, Early Onset, Lewy Body Disease
Patients With Alzheimer's Disease or Related Youth Disease
This study aims to determine factors related to diagnosis delay for patients with young onset dementia (first symptoms before 60 years old) who live in North of France.
- Conditions
- Alzheimer Disease, Early Onset, Lewy Body Disease, Frontotemporal Lobar Degeneration
- Trial name
- PARMAAJJ (NCT03508024)
- Where
- France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Lille
Liver Transplant
Interest of the Donor-specific Antibodies After Liver Transplantation
The study is a prospective observational mono center study Primary objective : Study the anti-HLA antibodies frequency preformed before liver transplantation and the kinetic of appearance of DSA and de novo complement-binding…
- Trial name
- vaLIDLIver (NCT03238443)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Lille
Inflammatory Disease, Covid19
Evaluation of the Impact of Lock Down and End of Lock Down on the Management of Patients With Inflammatory and Dysimmune Diseases Followed in the Context of IMMINeNT FHU and COVID-19
This questionnaire is distributed via a mailing list (e-mail) of patients treated within the framework of the FHU for pathologies including chronic inflammatory bowel diseases or IBD (Crohn's disease and ulcerative colitis)…
- Trial name
- CONFIMID (NCT04513561)
- Where
- France
- Volunteers
- 921 people
- Sponsor
- University Hospital, Lille
Seizure
Study of Predictors of Response to Anti Epilepsy in Epilepsy
Pharmacoresistant epilepsy remains around 30% despite the development of 25 anti epileptic drugs. Of course, this can be explained by pharmacoresistant epileptic brain diseases, as exemplified by some genetic diseases.
- Trial name
- RESISTANT (NCT02883712)
- Where
- France
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Coronavirus, COVID
Prevalence of Covid-19 in Children Admitted to Paediatric Emergency Departments During the Pandemic Period in France
Arriving in December 2019, Coronavirus COVID-19 infection is causing a global pandemic with high morbidity and mortality among adults and especially seniors. The child appears little or no affected by this infection.
- Conditions
- Coronavirus, COVID, Infection Viral
- Trial name
- INCOVPED (NCT04336761)
- Testing
- nasopharyngeal swab
- Where
- 6 sites in France
- Volunteers
- 901 people
- Sponsor
- University Hospital, Lille
Sars-CoV2
Hydroxychloroquine or Diltiazem-Niclosamide for the Treatment of COVID-19
No optimal antiviral intervention has been yet validated to treat COVID-19 disease. Comorbidities, such as older age, obesity, diabetes, history of cardiovascular diseases are associated with poor prognosis.
- Trial name
- HYdILIC (NCT04372082)
- Testing
- Standard of care (SOC), Hydroxychloroquine, Association of diltiazem and niclosamide
- Sponsor
- University Hospital, Lille