Clinical trials: sponsored by University Hospital, Limoges
Drug Resistance, Microbial, Biomarkers
INterest of the Negative Predictive Value of Integrons in the reduCtion of Large Broad-spectrum anTibiotics Consumption for Urinary Tract infectionS
Urinary tract infections (UTI), mainly driven by Gram-negative bacteria (GNB) are a frequent cause of hospitalization and the second cause of antibiotic prescription after lower respiratory tract infections.
- Conditions
- Drug Resistance, Microbial, Biomarkers, Urinary Tract Infections (UTI's), Antibacterial Agents
- Trial name
- INVICTUS (NCT07675018)
- Testing
- Detection of integrons, Gold standard
- Where
- 7 sites in France
- Volunteers
- 204 people
- Sponsor
- University Hospital, Limoges
Mentally Ill Old Subjects
Assessment of an Automated Telesurveillance System on Serious Falls Prevention in an Elderly Suffering From Dementia Specialized Care Unit: the URCC
2 URCC in the Limousin region will be equipped with the automated telesurveillance system. Patient will be selected by ward's geriatrician and randomized into two groups after informed consent.
- Trial name
- GET-BETTER (NCT01561872)
- Where
- France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Limoges
Lung Cancer, Exosomes
Molecular Profiling of Exosomes in Tumor-draining Vein of Early-staged Lung Cancer
This is an observational prospective single-center study of 30 patients operated for early-staged non-small cell lung cancer. The main aim is the analysis of molecular profiling of exosome with a sample in tumor-draining vein in…
- Conditions
- Lung Cancer, Exosomes, Non Small Cell Lung Cancer
- Trial name
- ExOnSite-Pro (NCT04939324)
- Testing
- Blood samples at 2 sites: peripheral vein and tumor-draining vein
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Limoges
Thoracic Ultrasound, Pleural Drain Removal
Evaluation of Thoracic Ultrasound in Monitoring Pleural Drainage in Postoperative Thoracic Surgery
The investigator would like to conduct a study in patients undergoing thoracic surgery to evaluate the effectiveness of thoracic ultrasound in the decision to discharge the patient after pleural drain removal.
- Trial name
- EchTHor (NCT05545566)
- Testing
- Thoracic ultrasound versus chest X-ray
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Limoges
Geriatrics, Oral Health Care
Evaluation of Efficacy of Coconut Oil Mouth Care for Non-autonomous Hospitalised Elderly People.
This is a prospective, longitudinal, randomised, open-label, multicentric, interventional, comparative superiority study. The main objective is to demonstrate the superiority of oral care with coconut oil on the oral status of…
- Trial name
- COCO-CARE (NCT07406425)
- Testing
- Coconut oil mouth care, Glycerin mouthwashes
- Where
- 2 sites in France
- Volunteers
- 94 people
- Sponsor
- University Hospital, Limoges
Ventilator-associated Pneumonia
B Lymphocyte Populations in the Pulmonary Microenvironment of Patients Under Mechanical Ventilation With or Without VAP (Ventilator-Associated Pneumonia)
Diagnosis of VAP relies on a set of non-specific clinical, biological, and imaging criteria. Understanding host-pathogen interactions and the mechanisms of deregulations leading to infection of pulmonary tissue appears essential.
- Trial name
- OLYMPE (NCT07436780)
- Where
- France
- Volunteers
- 75 people
- Sponsor
- University Hospital, Limoges
Non Small Cell Lung Cancer
Erlotinib and Docetaxel in Second Line of Treatment in Patients With Non Small Cell Lung Cancer
This 2 arms study will compare the efficacy and safety of treatment with sequential erlotinib plus docetaxel therapy versus docetaxel alone as second line treatment in patients with recurrent non-small cell lung cancer.
- Trial name
- TARSEQ (NCT01350817)
- Testing
- Erlotinib + docetaxel, Docetaxel
- Where
- 30 sites in France
- Volunteers
- 156 people
- Sponsor
- University Hospital, Limoges
Systemic Sclerosis, Dermatomyositis
Subcutaneous Injection of Sodium Thiosulfate for Ectopic Calcifications or Ossifications. A Pilot Study
Ectopic soft tissue calcifications or ossifications can complicate the course of numerous diseases; most of them are rare or very rare.
- Conditions
- Systemic Sclerosis, Dermatomyositis, iPPSD2
- Trial name
- ITS-PILOT (NCT03582800)
- Testing
- STS
- Where
- 11 sites in France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Limoges
Endometriosis, Pain
ENDometriosis: Evaluation of Detection and Need for ALGOlogic Care Before Surgery
Endometriosis surgery is required when medical treatment fails to release women from pain. However, complete surgery does not work every time to improve patients' symptoms.
- Trial name
- ENDALGO (NCT06997809)
- Testing
- pathway care
- Where
- 9 sites in France
- Volunteers
- 187 people
- Sponsor
- University Hospital, Limoges
POEMS Syndrome
POEMS Syndrome Treatment With Lenalidomide
POEMS syndrome is a rare form of B cell dyscrasia combining a proliferation usually of plasma cells, a polyneuropathy, osteocondensing bone lesions and multiple other clinical signs.
- Trial name
- POEMS (NCT01639898)
- Testing
- Lenalidomide and dexamethasone
- Where
- 11 sites in France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Limoges
Colorectal Cancer
Identification of the Most Suitable Questionnaire to Assess the Sexual Function of Women Living in France After Colorectal Cancer Surgery
Sexual quality of life is rarely mentioned by physicians during follow-up consultations, even though it is the source of a significant deterioration in quality of life (QOL).
- Trial name
- EVAS-CCR (NCT05391321)
- Testing
- administration of the 4 quality of sexual life questionnaires
- Where
- France
- Volunteers
- 23 people
- Sponsor
- University Hospital, Limoges
Apnea of Prematurity
MICropsampling for CAffeine in PREMature Newborns
Caffeine is one of the top five most prescribed drugs in neonatology. Caffeine has many beneficial impacts on preterm infants (cardiac, neurologic and pulmonary). One of these beneficial impacts is to prevent apnea.
- Trial name
- MICCAPREM (NCT07779915)
- Testing
- collection of an extra drop of capillary blood
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Limoges
Amyotrophic Lateral Sclerosis
French-German Cohort Study to Determine Factors Associated With Weight Loss in Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease. Studies have shown the importance of weight loss at the time of diagnosis and during the progression of the disease.
- Trial name
- FG-CoALS (NCT06147843)
- Testing
- Blood sample
- Where
- 9 sites in France, Germany
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Limoges
Giant Cell Arteritis (GCA)
Kinetics of C-Reactive Protein in Giant Cell Arteritis Following Glucocorticoid Initiation: A Pilot Study (GIDEON)
We propose to analyze the kinetics of the main marker of inflammation in GCA in order to understand its links with initial clinical manifestations and the possible appearance of complications and/or relapses.
- Trial name
- GIDEON (NCT07720804)
- Testing
- Blood tests to measure CRP
- Volunteers
- 40 people
- Sponsor
- University Hospital, Limoges
Lymphoma, B-cell, Aggressive Non-Hodgkin (B-NHL)
Exosomes and Immunotherapy in Non-Hodgkin B-cell Lymphomas
Diffuse large B-cell lymphomas (DLBCL) are highly aggressive and heterogeneous B-cell lymphoma that would imminently be fatal without treatment.
- Trial name
- ExoReBLy (NCT03985696)
- Testing
- blood sample
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Hematologic Cancer
The Point of View of Hematological Cancer Patients and Their Loved Ones Regarding Spirituality
The management of patients with malignant hemopathy is based on comprehensive management. In this context and faced with the various difficulties encountered by cancer patients, the question of spirituality and its experience is…
- Trial name
- SPIRIHEMATO (NCT04412135)
- Testing
- spirituality
- Sponsor
- University Hospital, Limoges
Colorectal Cancer
Use of Alternative and Complementary Medicine by Colorectal Cancer Patients
Complementary and alternative medicine (CAM) is defined by the National Center for Complementary and Alternative Medicine as "a group of diverse medical and health systems, practices and products that are not currently considered…
- Trial name
- ALTERNATIVCCR (NCT06779669)
- Testing
- Questionnaire CAM
- Where
- France
- Volunteers
- 217 people
- Sponsor
- University Hospital, Limoges
Organ Transplantation
Optimizing Long-term Survival in Organ Transplantation: From Physiopathology to Optimized Patient Management
Increased indications for transplantation continue to worsen the shortage of organs and need the extension of graft sampling criteria and the search for new potential sources of organs.
- Trial name
- BIOSUPORT (NCT03997253)
- Testing
- blood and urine samples
- Where
- 4 sites in France
- Volunteers
- 430 people
- Sponsor
- University Hospital, Limoges
Infection, COVID-19
COVID 19-Caregivers IGg Seroconversion
According to recent publications, the percentage of caregivers infected with COVID 19 is evaluated between 10 and 30% . This great variability is due, on the one hand to the intensity of the influx of covid plus patients and, on…
- Trial name
- CoSigS (NCT04353323)
- Testing
- Blood sampling
- Where
- France
- Sponsor
- University Hospital, Limoges
Child Development
Prospective Monitoring of Children Born in Haute Vienne From Uterine Life to Adulthood
The purpose of this survey is to collect data from intrauterine life until the age of 18 of children born in Haute Vienne. The interest to realize such survey is to find correlations and interactions that may exist between the…
- Trial name
- NEHAVI (NCT02674087)
- Where
- 3 sites in France
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges