Clinical trials: sponsored by University Hospital, Limoges
Sodium Thiosulfate, Ectopic Ossification
Treatment of Ectopic Calcification / Ossification With Sodium Thiosulfate (CATSSO)
Ectopic calcification and ossification complicate many diseases, which are rare for the most part. These calcifications (or ossifications) are generally classified according to their apparent formation mechanism.
- Trial name
- NCT03979378
- Where
- 7 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Limoges
Prostate, Ejaculation
Exploration of Ejaculation Changing Mechanism After Surgery for Benign Prostatic Hyperplasia
Every year in France, more than 60 000 people are operated for benign prostatic hyperplasia (BPH). This surgery is accompanied by a change or even a loss of ejaculations externalized what constitutes the main constraint for…
- Conditions
- Prostate, Ejaculation, Benign Prostatic Hyperplasia
- Trial name
- EMMECH (NCT02918227)
- Testing
- Search retrograde ejaculation
- Where
- 3 sites in France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Limoges
Autoimmune Bullous Dermatose
Pharmacokinetics Study of Mycophenolic Acid in Patients With an Autoimmune Bullous Dermatose, Pemphigus or Cicatricial Pemphigoid.
The main autoimmune bullous dermatoses are pemphigus and cicatricial pemphigoid. Pemphigus is an autoimmune dermatological disease characterized by the production of anti-desmoclesin antibodies 1 and 3, affecting the skin and…
- Trial name
- PEMPA (NCT02993133)
- Testing
- Cellcept® in autoimmune bullous dermatoses
- Where
- 3 sites in France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Limoges
Severe Sepsis, Inflammatory Response Syndrome, Systemic
Following of Myeloid-derived Suppressor Cells (MDSC) in Severe Sepsis: What Relationship With Systemic Inflammatory Syndrome?
Sepsis remains a major cause of death in developed countries. A better understanding of the mechanisms involved in the regulation of inflammatory and immune response of patients with severe sepsis is an important step that could…
- Trial name
- MDSC (NCT02903082)
- Testing
- Residue of blood further to NFS, Residue of blood further to preoperative workup, Bone marrow collected during a myelogram carried out for hematological pathology workup
- Where
- France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Limoges
Death
General Practitioners' Felt With Their Patients' Death (REGIDAQ)
Very few studies are dealing with the way general practitioners feel the death of their patients. Main studies about that subject are qualitative.
- Trial name
- REGIDAQ (NCT03272035)
- Where
- France
- Volunteers
- 481 people
- Sponsor
- University Hospital, Limoges
Healthy Volunteers, Children With HSP
Polymorphism of the IgH Locus Regulatory Region as a Prognostic Factor During Immune Pathologies.
The investigators previously showed that both antibody class switching (from IgM to IgG, IgA or IgE) and antibody secretion are controlled by a polymorphic "3' regulatory region" (3'RR) of the immunoglobulin heavy chain (IgH)…
- Conditions
- Healthy Volunteers, Children With HSP, Subject With Allergy, Lymphoma
- Trial name
- PRIERR (NCT01715623)
- Testing
- a blood sample
- Where
- 4 sites in France
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Anesthesia, Epidural
Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Third Trimester Medical Termination of Pregnancy Analgesia : a Randomized Study. (PCEA-IMG)
Background : Recently, delivery of local anaesthetics via Programmed Intermittent Epidural Bolus (PIEB) has been shown to improve labour epidural analgesia compared to delivery via Continuous Epidural Infusion (CEI).
- Trial name
- PCEA-IMG (NCT02563821)
- Testing
- Patient Controlled Epidural Analgesia for third trimester termination of preganancy analgesia, Levobupivacaine, sufentanil
- Where
- France
- Volunteers
- 37 people
- Sponsor
- University Hospital, Limoges
Breast Cancer
Adapted Physical Activity Effect on Aerobic Function and Fatigue at Home in Patients With Breast Cancer Treated in Adjuvant or Neoadjuvant Phase
Physical exercise has been identified as a major item of many chronic diseases and cancer rehabilitation. It contributes to an improvement in the quality of life and to a decrease in the current treatment side effects and…
- Trial name
- APAC (NCT01795612)
- Testing
- physical activity
- Where
- France
- Volunteers
- 94 people
- Sponsor
- University Hospital, Limoges
Glomerulonephritis, Membranous, Neonatal Diseases and Abnormalities
Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization
Problems of compatibility between a mother and her child are frequent. The most well-known case can be illustrated by the fetomaternal blood group incompatibility (rhesus factor) which can induce severe anemia of the fetus.
- Conditions
- Glomerulonephritis, Membranous, Neonatal Diseases and Abnormalities, Hemochromatosis
- Trial name
- NCT00199628
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Limoges
Aspirin Resistance
Aspirin Resistance and Prognosis of Patients With Critical Limb Ischaemia
Acetylsalicylic acid (Aspirin, ASA) is the most widely prescribed drug used in primary and secondary prevention of cardiovascular disease.
- Trial name
- Aspirine (NCT01104441)
- Where
- 2 sites in France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Limoges
Fear
Validation of a Scale of Self-assessment of Fear Faces in Children 4 to 12 Years
Since the 2000s, the experiences of children and especially their fear during a consultation, a treatment or examination is food for thought in our establishment. There is no tool validated self-assessment of fear to 6 faces.
- Trial name
- TROUILLOMETRE (NCT02675504)
- Testing
- Placing a scale self-assessment of fear
- Where
- France
- Volunteers
- 544 people
- Sponsor
- University Hospital, Limoges
The Elderly of 75 Years and Living in Nursing Homes
Assessment of an Automated Telesurveillance System on the Incidence of Serious Falls in Nursing Homes
3 Nursing homes in the Limousin region will be equipped with the automated telesurveillance system. Patient will be selected by general practitioner and randomized into two groups after informed consent.
- Trial name
- TELEHPAD (NCT01551121)
- Testing
- It will then allow them to intervene at the right time and the right place
- Where
- France
- Volunteers
- 216 people
- Sponsor
- University Hospital, Limoges
Primary Sjögren's Syndrome
Primary Sjögren Syndrome
Primary Sjögren syndrome (pSS) is an inflammatory, autoimmune, multiorgan disease often involving the central and peripheral nervous systems.
- Trial name
- NeuroSenSS (NCT01989819)
- Testing
- skin biopsy
- Where
- 7 sites in France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Cancer, Tiredness
Interest of Daily Physical Activity After Cancer Treatment
Many studies have demonstrated the beneficial effects of Adapted Physical Activity (APA) in different cancer types. It therefore seems necessary to assess spontaneous Physical Activity in order to integrate it to the overall…
- Trial name
- APQ (NCT02013921)
- Testing
- Physical activity
- Where
- France
- Volunteers
- 31 people
- Sponsor
- University Hospital, Limoges
Cognitive Diseases
The Cognitive and Cardiovascular Health in the Elderly Study
The main objective of this study is to look for the interest forecast of the IPS as infra-clinical cardiovascular marker in the prediction of a change of the cognitive functions (MCI) at the elderly of 70 and more years old…
- Trial name
- COACHES (NCT01979432)
- Testing
- Cardiovascular evaluation
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Limoges
Rheumatoid Arthritis
Pain Evaluation in Rheumatoid Arthritis
Rheumatoid Arthritis (RA) is an inflammatory chronic rheumatism where the pain remains the priority domain of improvement for the patients instead a good control of the inflammatory disease by treatments, even biotherapeutics .
- Trial name
- Douleur-PR (NCT01706029)
- Where
- 7 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Limoges
Anesthesia
Facial Mask Tightness: A Comparative Study
A correct preoxygenation can be obtained after a 3min delay of calm ventilation through a tight mask thereafter mask is used to make the patient breathing before intubation.
- Trial name
- EMAF (NCT02778984)
- Testing
- QuadraLite masks, standard mask
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Limoges
Renal Transplant
Pharmaco-economical Study in Kidney Transplantation
The prevalence of renal acute rejection in transplantation is reduced thanks to the optimized use of immunosuppressive drugs. However, graft survival at ten years has not improved since then; this may be explained in part by the…
- Trial name
- EPHEGREN (NCT01989832)
- Where
- France
- Volunteers
- 570 people
- Sponsor
- University Hospital, Limoges
Kidney Disease
Designing a Bayesian Model of the Plasma Clearance of Calcium Edetate de Sodium for the Calculation of GFR and Validity Compared to the Renal Clearance of Inulin
Diagnosis of patients with renal insufficiency and recommendations for medical treatment of patients who suffer from chronic renal failure are based on the different stages of Glomerular Filtration Rate (GFR).
- Trial name
- DFGBay (NCT02300376)
- Testing
- Dosage of Calcium edetate de sodium
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Limoges
Prosthesis Loosening
Efficacy of Risedronate in Patients With Painful Periprosthetic Resorption of the Hip Prothesis
This is an experimental study, prospective, comparative. This clinical trial is randomized and double-blind, Residronate versus placebo.
- Trial name
- PTH (NCT02744482)
- Testing
- risedronate
- Where
- France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Limoges