Clinical trials: sponsored by University Hospital, Limoges
Breast Cancer, Colorectal Cancer
Pharmacokinetic Study of Capecitabine in Elderly Cancer Patient (≥ 75 Years)
The aim of the study is to determine blood concentration evolution of capecitabine and its active metabolites, in elderly patient 75 years and more.
- Trial name
- capagec (NCT00812864)
- Testing
- Capecitabine
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Limoges
Cancer
Prophylaxis of Thrombosis With Implantable Devices for Central Venous Access in Cancer Patients
This is a Phase III open-labed, multicenter, prospective, randomised study, and comparative 3-arms of 140 patients (i.e. 420 total patients).
- Trial name
- NCT00199602
- Testing
- warfarine - low molecular heparin
- Where
- France
- Volunteers
- 420 people
- Sponsor
- University Hospital, Limoges
Septic Shock
Transpulmonary Thermodilution and Transesophageal Echocardiography in Early Septic Shock
The purpose of this study is to assess the concordance of therapeutic changes proposed after an early hemodynamic evaluation (hemodynamic profile) in septic shock patients using jointly the transpulmonary thermodilution technique…
- Trial name
- HEMOSEPSIS (NCT01188993)
- Testing
- early septic shock
- Where
- 2 sites in France
- Volunteers
- 153 people
- Sponsor
- University Hospital, Limoges
Breast Cancer
Adapted Physical Activity Effect and Fatigue in Patients With Breast Cancer
Physical exercise has been identified as a major item of many chronic diseases and cancer rehabilitation. Therefore, physical activity for health is a valid and relevant way to improve quality of life and to manage cancer patient…
- Trial name
- SAPA (NCT01322412)
- Where
- France
- Volunteers
- 44 people
- Sponsor
- University Hospital, Limoges
Stroke
Follow-up of Patients' Physical Activity in Post-hospitalization
Physical exercise has been identified as a major item of many affecting many chronic diseases and stroke rehabilitation. It contributes to an improvement in the quality of life and to a decrease in the current treatment…
- Trial name
- TICAA'DOM (NCT01822938)
- Testing
- incentive program for physical activity
- Where
- France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Limoges
Hepatocyte Nuclear Factor 1-beta
Long Term Follow up of a Cohort of Children With TCF2 Mutation:Evolution of Endocrine and Renal Function
Anomalies of renal development are well know for patients treated for MODY-5 diabetes due to TCF2 mutation.A recent study confirms the existence of pediatric patients having TCF2 mutation but presenting renal anomalies…
- Trial name
- TCF2 (NCT00760331)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Limoges
Recurrent Pregnancy Losses, Preeclampsia
Study of the Role of Tissular Maternofetal Alloimmunization in Placentation Pathologies
Justification: We have recently demonstrated that maternofetal alloimmunization was not limited to blood cells: maternal alloimmunization against a glomerular podocyte antigen expressed by the placenta can induce neonatal…
- Conditions
- Recurrent Pregnancy Losses, Preeclampsia, Intervillositis
- Trial name
- NCT00456118
- Where
- 7 sites in France
- Volunteers
- 83 people
- Sponsor
- University Hospital, Limoges
Bronchoscope Users
Reusable Flexible Bronchoscopes Versus Single Use Bronchoscopes : a Satisfaction Survey
Reusable (RU) flexible bronchoscopes (FB) require intermediate level disinfection operations to prevent transmission of infectious agents from patient to patient.
- Trial name
- NCT03392610
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Limoges
Nephrotic Syndrome Steroid-Dependent, Interleukin 2
Treatment of Steroid Dependent Idiopathic Nephrotic Syndrome in Children With Low Doses of Interleukin 2: a Pilot Study
NIL-2 is a clinical trial designed to evaluate the efficacy and safety of low doses of Interleukin2 in the treatment of recently diagnosed, steroid dependent idiopathic nephrotic syndrome in children.
- Trial name
- NIL-2 pilote (NCT02997150)
- Testing
- IL-2 Low dose
- Sponsor
- University Hospital, Limoges
Non Small Cell Lung Cancer
Concomitant Radio-chemotherapy in the Elderly
The purpose of this study is to evaluate the safety of non small cell lung cancer (NSCLC) treatment with cisplatin and oral vinorelbine administered weekly associated with concomitant radiotherapy in elderly patients.
- Trial name
- RACCOSA (NCT01029678)
- Testing
- Cisplatin IV, Vinorelbine, Radiotherapy
- Where
- 5 sites in France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Limoges
Bronchioalveolar Lavage
Cardiopulmonary Effects of Bronchoalveolar Wash on Patients With Acute Respiratory Distress Syndrome
The acute respiratory distress syndrome (ARDS) is a clinical syndrome characterized by an inflammatory pulmonary edema, severe hypoxia and endothelial and epithelial diffuse aggression.
- Trial name
- FLOOD (NCT02818049)
- Testing
- Bronchoalveolar Lavage
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Limoges
Circulatory Failure, Echocardiography
Diagnostic Performance of Echocardiography Performed by Emergency Physicians After a Basic Training
After a basic training to echocardiography, emergency physicians will have to answer simple clinical questions about circulatory failure mechanisms.
- Trial name
- ECHOBEDSIDE (NCT02974790)
- Testing
- Echocardiography
- Where
- France
- Volunteers
- 89 people
- Sponsor
- University Hospital, Limoges
Amyotrophic Lateral Sclerosis
Hypermetabolism in ALS Using Six REE Formulas
Introduction: About 50-60% of Amyotrophic Lateral Sclerosis (ALS) is characterized by hypermetabolism, defined as 10% or more excess resting energy expenditure (REE) compared to theoretical values.
- Trial name
- NCT03382392
- Testing
- Assesment of REE in ALS patients compared to control populations and to compare six formulas commonly used to predict REE.
- Where
- France
- Volunteers
- 449 people
- Sponsor
- University Hospital, Limoges
Amyotrophic Lateral Sclerosis
Resting Energy Expenditure Equations in Amyotrophic Lateral Sclerosis, Creation of a ALS-specific Equation
Introduction: Resting energy expenditure (REE) formulas for healthy people (HP) are used to calculate REE (cREE) in amyotrophic lateral sclerosis (ALS) patients.
- Trial name
- NCT03378375
- Testing
- nutritional assessement
- Where
- France
- Volunteers
- 315 people
- Sponsor
- University Hospital, Limoges
Severe Sepsis With Septic Shock
Immune Reconstitution of Immunosuppressed Sepsis Patients
A multicenter, randomized, double-blinded, placebo-controlled study of two dosing frequencies of recombinant Interleukin-7 (CYT107) treatment to restore absolute lymphocyte counts in sepsis patients; IRIS-7A (Immune…
- Trial name
- IRIS-7a (NCT02797431)
- Testing
- Interleukin-7
- Where
- 3 sites in France
- Volunteers
- 16 people
- Sponsor
- University Hospital, Limoges
Edema
Oedematous Lower Limb Subcutaneous Drainage in Palliative Care
Background : Edema of lower extremities is a concern ranging from 19 % to 60% of palliative cancer patients. Lymphedema decreases mobility, induces pain, impacts daily activities, esthetic and behavior.
- Trial name
- DSOPAL (NCT02473744)
- Testing
- subcutaneous drainage
- Where
- 7 sites in France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Limoges
Chronic Migraine
OnabotulinumtoxinA Injections in Chronic Migraine, Targeted to Sites of Pericranial Myofascial Pain
This study was an observational, open-label, cohort-study conducted in accordance with the principles of the Helsinki Declaration.
- Trial name
- NCT03175263
- Volunteers
- 57 people
- Sponsor
- University Hospital, Limoges
Breast Cancer, Ovarian Cancer
Pilot Study Evaluating the Oncogramme: Analysis of Response to Induction Treatment of Patients With Breast or Ovarian Cancer.
The choice of treatments for cancers by systemic way - chemotherapy, hormone therapy and targeted therapies - is currently defined by criteria for population groups and not to an individual.
- Trial name
- ONCO S-O (NCT02910622)
- Testing
- Chimio-oncogramme
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Limoges
Neck Cancer
Physical Activity Program and Nutrition Therapeutic Education During Treatment of Head and Neck Cancer Population
The purpose of this study is to examine the feasibility of resistance training and physical functioning associated with nutrition therapeutic education in head and neck cancer patients, during their treatment (chemotherapy with…
- Trial name
- APANVADS (NCT01910753)
- Testing
- APA
- Where
- 2 sites in France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Limoges
Ischemia
Renal Graft Function After Treatment With Erythropoietin (EPO)
Background : Numerous studies have outlined the cellular pleiotropic effects of erythropoietin (EPO) and their role in the prevention of ischemic-reperfusion lesion such as after acute ischemic injury of the brain or the heart.
- Trial name
- FRETEP (NCT01450878)
- Testing
- beta-epoietin
- Where
- 18 sites in France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Limoges