Clinical trials: sponsored by University Hospital, Limoges
Obesity, Morbid Obesity
Monitoring Obese Patients : Impact on the Frequency of Monitoring Weight
The literature data show that long-term monitoring has an effect on weight loss, comorbidity and on improving the quality of life.
- Conditions
- Obesity, Morbid Obesity, Quality of Life
- Trial name
- SUIVIOBESITE (NCT02374866)
- Testing
- closer monitoring
- Where
- France
- Volunteers
- 96 people
- Sponsor
- University Hospital, Limoges
Non-Small Cell Lung Cancer, Chronic Obstructive Pulmonary Disease
Detection of Circulating Endothelial Progenitors Cells (EPCs) in Non-small Cell Lung Cancer (NSCLC)
Bone-marrow-derived progenitor cells (EPCS) play an important role in neovascularization and tumor growth. In lung cancer, angiogenesis is an important event in mechanisms of tumor proliferation and metastasis.
- Trial name
- CBNPC:PCE (NCT00826683)
- Testing
- Enumeration of endothelial cell progenitor in peripheral blood by flow cytometry, Endothelial cell progenitor characterization by primary cell cultures
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Anemia
Early Detection of Anaemia During the Maternity
Estimate the efficiency of a strategy of premature screening of the maternal anaemia during the first quarter of pregnancy versus the usual strategy of screening of the anaemia during the sixth month.
- Trial name
- anémie (NCT00827463)
- Testing
- dosage of the NFS and iron
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Limoges
Alzheimer Disease
Conservation of Praxis in the Food and Alzheimer Disease
The insanities, priority of public health in 2008, have significant prevalency in Limousin, region in the ageing demography (1/3 of the population is more than 60 years old against 1/5th of average in France).
- Trial name
- PRAXALIM (NCT01743534)
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Limoges
IgA Nephropathy
IgA Nephropathy, Lymphocyte Homing and IgA Class Switch
IgA nephropathy (IgAN) is the most common primary glomerulonephritis in the world and it represents an important cause of end-stage kidney failure.
- Trial name
- NIDOCIGA (NCT01775527)
- Testing
- blood test
- Where
- France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Kidney Transplantation
BIOMARGIN European, Ambispective Cohort of Adult and Paediatric Renal Transplant Patients
Biomargin is a European research program aimed at evaluating the diagnostic performance of biomarkers with respect to renal graft injuries, as well as their prognostic performance with respect to 3-year and 5-year graft outcomes.
- Trial name
- BECS (NCT02832661)
- Where
- 6 sites in Belgium, France and 1 more
- Volunteers
- 500 people
- Sponsor
- University Hospital, Limoges
the Elderly of 75 Years and Older Living at Home
Prospective Randomized Study of the Impact on the Autonomy of the Elderly of 75 Years of Age and Older by the UPSAV
Background : The evolving concept of frailty was born in the United States under the term of " frail elderly ". It allows describing geriatrics situations, dominated by the weakness or the functional instability of aged person…
- Trial name
- GEROPASS (NCT01369797)
- Testing
- specific intervention
- Where
- France
- Volunteers
- 440 people
- Sponsor
- University Hospital, Limoges
Hepatitis B, Renal Failure With Tubular Necrosis
Assessment and Monitoring of Renal Proximal Tubular Tolerance of Nucleoside and Nucleotide Analogues Using Early Screening Tools in Patients Chronically Mono-infected With Hepatitis B Virus
Nucleotide analogues are associated in the long term with a risk of proximal tubular nephropathy (PT) with loss of phosphate, and, when compensatory mechanisms are overwhelmed, with osteopenia or osteoporosis.
- Trial name
- HBVSECURE (NCT01500265)
- Testing
- plasma and urine samples, sample with ADN
- Where
- 25 sites in France
- Volunteers
- 216 people
- Sponsor
- University Hospital, Limoges
Sepsis With Acute Organ Dysfunction
Prognostic Interest of Leucocyte Immunophenotyping During the Acute Phase of Sepsis
Septic shock is still a major cause of death in ICU. Sepsis diagnosis is linked with many clinical, hemodynamic and biological criteria which have a low sensitivity and specificity if they are considered separately.
- Trial name
- SEPTIFLUX2 (NCT01995448)
- Testing
- Blood test
- Where
- 9 sites in France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Limoges
Discogenic Back Pain
Treatment of Discogenic Back Pain
Discogenic low back pain is the most common form of chronic low back pain. Its diagnosis is mainly based on MR imaging, showing MODIC I or II changes in patients with concordant symptomatology.
- Trial name
- EGID (NCT02089139)
- Testing
- Discogel, conventional treatment
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Limoges
Resistant Vascular Ulcers
Evaluation of the Cryopreserved Amniotic Membranes in the Care of Resistant Vascular Ulcers
To evaluate tolerance and efficiency of cryopreserved amniotic membranes in local treatment of resistant vascular ulcers. To evaluate complete cicatrisation, efficiency on pain, prevention of infection, improvement of quality of…
- Trial name
- MAUV (NCT00820274)
- Testing
- amniotic membranes
- Where
- 3 sites in France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Limoges
Pain
Procedures of Locoregional Analgesia and Quality of Life in Palliative Care Units
Number of patients in mobile palliative care units have pain of both nociceptive and neuropathic origin. In certain cases, procedures of locoregional analgesia can be helpful.
- Trial name
- TALViSoP (NCT01094912)
- Testing
- opioids
- Where
- 6 sites in France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Limoges
Childhood Idiopathic Nephrotic Syndrome
Efficacy of Rituximab For the Treatment of Calcineurin Inhibitors Dependent Nephrotic Syndrome During Childhood
Background Idiopathic nephrotic syndrome is a rare disease beginning during childhood and treated with immunosuppressants (i.e. steroids, mycophenolate mofetil, cyclophosphamide, cyclosporine).
- Trial name
- NEPHRUTIX (NCT01268033)
- Testing
- Rituximab
- Where
- 24 sites in Belgium, France
- Volunteers
- 26 people
- Sponsor
- University Hospital, Limoges
Colon Cancer
Evaluation of Interest Chemo-oncogramme in Patients With Colonic Adenocarcinoma Stage 4
In patients with colonic adenocarcinoma stage 4 which are potentially resectable metastases (lung and liver metastases), treatment with chemotherapy is necessary but not end in success in 10% of cases.
- Trial name
- Oncogramme (NCT02305368)
- Testing
- Chimio-oncogramme
- Volunteers
- 20 people
- Sponsor
- University Hospital, Limoges
Extended Ileal Resection Under Laparotomy, Total Proctocolectomy Under Laparotomy
Postoperative Analgesia in Abdominal Surgery: a Medico-economic Study
Background : Epidural anaesthesia is associated in abdominal surgery with reduced pain and postoperative respiratory complications together with quicker recovery of bowel function.
- Conditions
- Extended Ileal Resection Under Laparotomy, Total Proctocolectomy Under Laparotomy, Colectomy Left/Right/Total Under Laparotomy, Rectosigmoidal Resection Under Laparotomy
- Trial name
- PERIDIGE (NCT01470846)
- Testing
- epidural analgesia, PCA
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Limoges
Cardiac Surgery
Diagnostic Interest of Leukocyte Immunophenotyping Using Multiparameter 8-color Flow Cytometry in Heart Surgery
In septic patients, Septiflux1 study identified immature granulocytes which may have a diagnostic and prognostic interest. However, with these preliminary results it is not possible to make a difference between what is linked to…
- Trial name
- INFLUX (NCT02216019)
- Testing
- Whole blood
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Limoges
Valvular Disease
Filling Pressures of the Left Ventricle in Patients With Significant Aortic Stenosis
Left valvular heart disease has become one of the most common heart disease in Western countries. This disease evolve over many years and are characterized by a long phase where the patient is "asymptomatic".
- Trial name
- PRESSEVAL (NCT01727310)
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Limoges
Alzheimer's Disease
Inappropriate Medications Associated With Anticholinesterase and/or Memantine Treatment in the Elderly
In each of the 7 French areas that should be involved, patients aged 75 years and over from three different sectors will be included: the geriatric consultation unit (60%) and two kinds of nursing homes, private (20%) and state…
- Trial name
- MIDA (NCT00954616)
- Where
- 6 sites in France
- Volunteers
- 636 people
- Sponsor
- University Hospital, Limoges
Bacterial Resistance to Antimicrobial
Prevalence of Digestive Carriage of Integrons
Bacterial resistance to antimicrobials is an increasing problem. Doctors occasionally face genuine therapeutic dead-ends, when attempting to cure nosocomial infections and, more and more frequently, community-acquired infections.
- Trial name
- APIHA (NCT01985217)
- Where
- France
- Volunteers
- 492 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Malnutrition in the Elderly
Impact of the Time of Oral Nutritional Supplements (ONS) Consumption on Daily Alimentary Intakes of Malnourished Elderly
Malnutrition is a severe comorbidity in hospitalised patients, especially in elderly. The consumption of Oral Nutritional Supplements (NOS) is one of several tools for fighting against malnutrition.
- Trial name
- ACTICLAN (NCT01261663)
- Testing
- oral nutritional energy and protein enriched supplement (NOS)
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Limoges