Clinical trials: sponsored by University Hospital, Limoges
Hypereosinophilic Syndrome
Eosinophilia Diagnosis
Eosinophilia, defined by a blood eosinophil granulocytes rate greater than 500 / mm3, is frequently encountered in internal medicine.
- Trial name
- EOSINOPHILIM (NCT02581514)
- Testing
- Scheduled exams and diagnosis
- Where
- France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Limoges
Stroke
Validation and Standardisation of a Pool of Simplified Evaluation Aimed to the Diagnoses of Aphasic Disorders and Adapted to the Patients Suffering an Acute Phase of Stroke
Every year in France, from 100 000 to 145 000 people are affected by a stroke. 75% patients survived with aftereffects, in particular aphasic disorders.
- Trial name
- BESTA-AVC (NCT02548481)
- Testing
- BESTA scale
- Where
- France
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Glomerulonephritis, IGA
Study of the IgA Repertoire During IgA Deposition Nephropathy.
IgA plays a major role in mucosal and systemic immunity but retains mysterious and ambivalent aspects. They can thus, depending on the situation, prove to be capable of triggering either a protective inflammatory response or, on…
- Trial name
- ERINA (NCT04092491)
- Testing
- blood sample
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Pneumococcal Infections
Surveillance of Invasive Pneumococcal Infections in Adults (Excluding Meningitis)
Given the frequency and severity of invasive pneumococcal infections and questions about the place of VPC-13 in the prevention of pneumococcal infections in adults based on the presence of risk factors, current laboratory…
- Trial name
- SIIP (NCT03983616)
- Where
- France
- Volunteers
- 1,560 people
- Sponsor
- University Hospital, Limoges
Medication-related Osteonecrosis of the Jaw (MRONJ)
The PENTO Protocol in Medication-related Osteonecrosis of the Jaw
Medication-related osteonecrosis of the jaw (MRONJ) occurs after taking bisphosphonates or targeted therapies. It leads to a significant decrease in quality of life with pain, eating and chewing disorders, and malnutrition.
- Trial name
- PENTO (NCT05795647)
- Testing
- Pentoxifylline+Tocopherol
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Limoges
Motor Activity
Adapted Physical Activity Effect on Aerobic Function and in Patients in Pre Liver Transplantation
Physical exercise has been identified as a major beneficial factor in the management of patients suffering from many chronic diseases especially cancer and in the context of cardiac or pulmonary transplantation.
- Trial name
- FAPA (NCT02567591)
- Testing
- Physical activity
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Limoges
Age-related Macular Degeneration (AMD)
Assessment of the Knowledge and Needs of Patients With AMD Before a Therapeutic Patient Education Program is Put in Place
Age-related macular degeneration (AMD) is a disease that blurs the sharp, central vision you need for "straight-ahead" activities such as reading, sewing, and driving.
- Trial name
- DEMELE (NCT03690505)
- Testing
- Interviews
- Where
- France
- Volunteers
- 118 people
- Sponsor
- University Hospital, Limoges
Weaning-induced Pulmonary Edema
Hemodynamic Impact of the Spontaneous Ventilation Test in Patients at Risk of Weaning Pulmonary Oedema
Weaning-induced pulmonary edema (WIPE) from the ventilator is a frequent cause of extubation failure or delay, which prolongs the duration of invasive mechanical ventilation and the associated morbidity and mortality.
- Trial name
- WAPITI 2 (NCT07666880)
- Testing
- T-piece SBT, PS-ZEEP SBT
- Where
- 4 sites in France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Limoges
COPD
Trial Evaluating the Rate of Pneumothorax in Severe Emphysema Secondary to Endoscopic Volume Reduction With Two-stage ZEPHYR® Valves Versus Endoscopic Volume Reduction With One-stage ZEPHYR® Valves
Chronic obstructive pulmonary disease (COPD) affects 3.5 million people and is the third leading cause of death worldwide. Emphysema involves air retention in the lungs and is ultimately responsible for a major deterioration in…
- Trial name
- REPEAT (NCT06181357)
- Testing
- Endoscopic lung volume reduction in 2 stages, Endoscopic lung volume reduction in 1 stage
- Where
- 17 sites in France
- Volunteers
- 244 people
- Sponsor
- University Hospital, Limoges
Mechanically Ventilated Patients
Evaluation of Two Enteral Nutrition Strategies in Mechanically Ventilated Patients
The aim of this study is to compare two strategies of early enteral nutrition in terms of efficacy and complications in mechanically ventilated patients.
- Trial name
- NCT00199641
- Testing
- enteral nutrition
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Limoges
Coronavirus Infection
Gerontological Telemonitoring of Older Adults Living in Nursing Homes With COVID-19 Disease
Since the last 3 months the world copes with the novel coronavirus disease : Covid-19 emerged in China in the end of 2019. WHO declared the pandemic situation as a Public Health Emergency around the world on January 2020.
- Trial name
- COVIDeHPAD (NCT04337788)
- Testing
- telehealth applications
- Where
- France
- Sponsor
- University Hospital, Limoges
Autistic Disorder
Evaluation of the Efficiency of Treatment by BUMETANIDE on Autistic Children With a Known Ethiology
During a previous therapeutic trial, investigators showed that the bumetanide improved significantly autism. This trial showed that a therapeutic response was obtained in 75% of cases.
- Trial name
- BUMAUTEP (NCT02947880)
- Testing
- Bumetanide
- Where
- France
- Sponsor
- University Hospital, Limoges
Pain Due to Certain Specified Procedures, Neuropathic Pain
Early Administration of Botox® in Neuropathic Pain Due to Thoracoscopy or Thoracotomy
Botulinum toxin type A has been reported to inhibit the release of various pain neurotransmitters (SP, CGRP, glutamate) responsible for neurogenic inflammation, a process that results from the sensitization of C-fiber nociceptors…
- Trial name
- APTODON (NCT01325090)
- Testing
- BOTOX
- Where
- France
- Sponsor
- University Hospital, Limoges
Polypathology
Telemedicine - Evaluation of the Impact of a Telemedicine Device (DTM) on the Prevention of Emergency Department Visits and Hospitalizations of Nursing Home Residents Aged Polypathological
For several decades, there is an aging population, particularly in industrialized countries. This lengthening of the duration of life is accompanied by an increase in the number of chronically ill patients.
- Trial name
- GERONTACCESS (NCT04008472)
- Testing
- Telemedecine
- Where
- France
- Volunteers
- 428 people
- Sponsor
- University Hospital, Limoges
Cytomegalovirus
Detection of Human Cytomegalovirus in the Saliva
Direct DNA amplification, viral isolation and specific antibody measurement in saliva 1. From children in day care centers (samples collection will take place during a single week) 2.
- Trial name
- FcrèchMV (NCT00815802)
- Where
- France
- Volunteers
- 655 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Lupus Erythematosus, Systemic
Effect of Qi Gong Training on Quality of Life in Patients With Systemic Lupus Erythematous (LuQi)
Systemic Lupus Erythematosus (SLE) is chronic and systemic autoimmune disease that mainly affecting women and leading to organ damages especially skin, joints, kidneys, central nervous system and heart.
- Trial name
- LuQi (NCT02732470)
- Testing
- Qi Gong
- Where
- France
- Volunteers
- 33 people
- Sponsor
- University Hospital, Limoges
Retinitis Pigmentosa Syndrome
Evaluation of the Visual Field on the Ground
Retinopathy pigmentosa (which affects about 40,000 patients in France) leads to destruction of the peripheral retina. This condition, often familial, frequently affects young patients.
- Trial name
- ECVS (NCT03989622)
- Testing
- evaluation of the visual field on the ground
- Sponsor
- University Hospital, Limoges
Sleep Apnea
Branched-chain Aminoacids in Sleep Apnea Syndromes (ARSAS)
The initial hypothesis is that branched-chain aminoacids (BCAA) administration could be beneficial to patients suffering from sleep apnea syndrome (SAS), the aim of the present work is to verify this hypothesis.
- Trial name
- ARSAS (NCT01115686)
- Testing
- Branched-chain aminoacids
- Sponsor
- University Hospital, Limoges
Dry Eye Syndrome (DES)
Impact of Filtration on Autologous Serum Eye Drops
Dry eye disease accounts for nearly 25% of ophthalmology consultations, making it a commonly encountered condition. When conventional treatments fail autologous serum in the form of eye drops, have been proposed as a therapeutic…
- Trial name
- IFILCOSA (NCT07407101)
- Testing
- Serum dosage of TGF-β, IGF-1, EGF, Fibronectin and Vitamin A
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Limoges
Charcot-Marie-Tooth Disease, Type IA, Peripheral Neuropathy Hereditary
Physical Activity Level at Home in CMT1A Patients: Wearable Sensor Assessment
Charcot-Marie-Tooth disease type 1A (CMT1A) is the most common hereditary peripheral neuropathy, affecting approximately 26,000 patients in France.
- Conditions
- Charcot-Marie-Tooth Disease, Type IA, Peripheral Neuropathy Hereditary, Motor Activity, Walking, Difficulty
- Trial name
- CMT1A-HOME (NCT07591779)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Limoges