Clinical trials: sponsored by University Hospital, Limoges
Chronic Hepatitis B Virus
Gene Discovery in CHB Patients to Identify Unknown Pathways That Lead to B and NK Cell Deregulation
Natural Killer (NK) and B cell immune responses occur during the early stages of infection and are essential to eradicate it. Yet, chronic hepatitis B (CHB) infection occurs because the antiviral immune response is insufficient.
- Trial name
- LiNKeB2 (NCT06853886)
- Testing
- blood sample HBV patient, blood sample healthy volunteers
- Where
- 3 sites in France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Horton Disease
Chewing Gum Test for the Diagnosis of Giant Cell Arteritis (Horton's Disease) - ChewingHort
It is hypothesized that chewing-gums may be a useful test to unmask jaws intermittent claudication in order to enhance the diagnosis of Giant Cell Arteritis (GCA).
- Trial name
- ChewingHort (NCT04010097)
- Testing
- chewing gum
- Where
- 6 sites in France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Hematological Malignancies
Complementary and Alternative Medicine Among Patients With Hematologic Malignancies in France
Integrative medicine promotes the incorporation of elements from complementary and alternative medicines (CAM) into patient care.
- Trial name
- COMPLHEMATO (NCT07541326)
- Testing
- Questionnaire on Complementary and Alternative Medicines (CAM)
- Where
- 2 sites in France
- Volunteers
- 85 people
- Sponsor
- University Hospital, Limoges
Laparoscopic Cholecystectomy Surgery
Esmolol Versus Sufentanil on the Quality of Post-cholecystectomy Recovery Laparoscopic Anaesthesia With Orotracheal Intubation on an Outpatient Basis
There are 120,000 outpatient laparoscopic cholecystectomies with orotracheal intubation per year in France. Sufentanil is the most commonly used morphine during surgery in France, but morphines have harmful effects when…
- Trial name
- ESA (NCT07019818)
- Testing
- Esmolol Hcl 10Mg/Ml Inj, Sufentanil 5 mcg
- Where
- 2 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Limoges
Tick-borne Encephalitis
Tick-borne Encephalitis Virus Research in Limousin
Cases of encephalitis of varying severity have been described in recent years in eastern France involving tick-borne encephalitis virus (TBEV).
- Trial name
- VITAL (NCT05941546)
- Testing
- anti-TBEV serology
- Where
- France
- Volunteers
- 878 people
- Sponsor
- University Hospital, Limoges
Sjogren's Syndrome, Digestive System Abnormalities
Evaluation of the Prevalence of Functional Digestive Disorders During Primary Sjögren Gougerot Syndrome
the investigators propose to carry out a prospective study consisting of a systematic research of digestive symptoms in patients with SGSp with the validated Global symptom score (GSS) questionnaire, which allowed to grades…
- Trial name
- GASTRO-SGS (NCT03157011)
- Testing
- Global symptom score (GSS) questionary
- Where
- France
- Volunteers
- 151 people
- Sponsor
- University Hospital, Limoges
Stroke, Physical Inactivity
How Stroke Affects Leg Muscles When Walking
Stroke is the leading cause of acquired disability in France and the third leading cause worldwide. This research will : Test how reliable current medical methods are for measuring muscle activity.
- Conditions
- Stroke, Physical Inactivity, Spasticity, Muscle, Walking, Difficulty
- Trial name
- MCOACT (NCT07504627)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Limoges
Anxiety
Impact of a Child-Parent Preoperative Accompanying Procedure on the Anxiety of Children Aged 5 to 12 With Scheduled Surgery
In France, during surgery, only 4% of parents are present at induction, most often for children with disabilities with iterative interventions.
- Trial name
- I-PPOP (NCT03205397)
- Testing
- Experimental Group, usual care
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Limoges
Scleroderma, Systemic
Scleroderma: Functional Disability Between the Dominant and Contralateral Hand.
Systemic sclerosis is an autoimmune disease in which the hand is responsible for 75% of the overall disability. Management is based on systemic treatments combined with kinesitherapy aimed at maintaining joint amplitudes…
- Trial name
- SCLERO-HAND (NCT05171114)
- Testing
- Measurement of joint amplitudes
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Limoges
Femoral Fractures
Pilot Study Comparing Two Techniques of Taking Care Analgesic in Patients 70 and Older, Awaiting Surgery After Extracapsular Fracture of the Proximal Femur
The fracture of the proximal femur is a common traumatic pathology in patients aged over 70 years, associated with a mortality of 20 to 30% a year. The care is delayed emergency.
- Trial name
- ALGOFRACT (NCT03185663)
- Testing
- traction-stuck, a pillow between the legs
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Limoges
Orthopedic Surgery
Impact of a Technique of Massage During the First Week of Hospitalization on the Recycling of the Mobility of the Knee Further to the Installation of Knee Replacement
During fthe first postoperative days, physiotherapists supported patients with knee replacement in orthopaedics of Saint-Junien's and Limoges' hospitals.
- Trial name
- PTGMass (NCT02278627)
- Testing
- manual lymphatic drainage
- Where
- France
- Volunteers
- 44 people
- Sponsor
- University Hospital, Limoges
Surgical Operation With the Settle of a Redon's Drain
Study of a Therapy Without Drugs, Supplementary to an Usual Treatment for the Pains Caused by Removing the Redon's Drain From a 7 to 17 Years Old Child in Pediatric Surgery.
The 3rd governmental plan of fighting against the pain favored the development and the evaluation of the efficiency of the non pharmacological methods.
- Trial name
- TOUTETDOU (NCT02047591)
- Testing
- Relaxing-touch method
- Where
- France
- Volunteers
- 232 people
- Sponsor
- University Hospital, Limoges
The Elderly
Elderly Chronic Diseases Online Biometric Analysis Home Living Technology
The elderly or people with disabilities want to remain in their homes even when their health condition has been getting worse. This project aims to demonstrate that home automation and telemonitoring can lead to develop a home…
- Trial name
- e-COBAHLT (NCT02155686)
- Testing
- Biosensors, Home automation
- Where
- France
- Volunteers
- 536 people
- Sponsor
- University Hospital, Limoges
D020521
fNIRS in the Evaluation of Cognitive-motor Interference in Post-stroke Patients
This study evaluates cognitive-motor interference in stroke patients who is responsible an alteration of spatio-temporal gait parameters.
- Trial name
- ICM-AVC (NCT03559283)
- Testing
- Walking and Record Cortical Activity
- Where
- France
- Volunteers
- 11 people
- Sponsor
- University Hospital, Limoges
Auto-Immune Diseases
Alternative Care in Patients With Auto-Immune Diseases
Patients followed in Internal Medicine bring together favorable conditions for the use of alternative medicines. While some are recognized for their benefits, some can, on the contrary, harm the patient.
- Trial name
- Alter-MAI (NCT04094259)
- Testing
- Questionnaire.
- Where
- France
- Volunteers
- 121 people
- Sponsor
- University Hospital, Limoges
Liver Transplantation, Immunosuppression
Evaluation of the Benefits of Administering Immunosuppressive Drugs as Single Daily Doses Over the First Year After Liver Transplantation (EASY)
World Health Organization considers non-adherence has a strong negative impact on the health of patients with chronic diseases. In transplantation, adherence to immunosuppressive drug regimens associates with late rejection and…
- Trial name
- EASY (NCT06354179)
- Testing
- XR-tacrolimus QD + MMF BID then MMF QD, XR-tacrolimus QD + MMF BID, LCP-tacrolimus QD + MMF QD then MMF QD
- Where
- 18 sites in France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Limoges
Septic Shock, Echocardiography
Prognostic Assessment of Diastolic and Systolic Left Ventricular Function in Septic Shock
Sepsis induces a reversible systolic and diastolic cardiac dysfunction. The presence of a left ventricular (LV) diastolic dysfunction during septic shock could favor harmful volume overload.
- Conditions
- Septic Shock, Echocardiography, Diastolic Dysfunction, Hyperkinesia
- Trial name
- PRODIASYS2 (NCT02918214)
- Where
- 10 sites in France
- Volunteers
- 440 people
- Sponsor
- University Hospital, Limoges
Allergy
Flow Cytometry Applied to the Diagnosis of Peri-anaesthesic Reactions
To assess diagnostic accuracy of flow cytometry applied to the diagnosis of allergy to neuro-muscular blockers and to the determination of the neuro-muscular blocker (NMB) which may be used for an ulterior anaesthesia in case of…
- Trial name
- CYPREANE (NCT01305161)
- Testing
- Blood simple
- Where
- 4 sites in France
- Volunteers
- 129 people
- Sponsor
- University Hospital, Limoges
Idiopathic Nephrotic Syndrome
A National Prospective Cohort of Patients With Idiopathic Nephrotic Syndrome Beginning in Childhood.
Pediatric idiopathic nephrotic syndrome (INS) is a rare disease for which the optimal therapeutic strategy has not yet been defined.
- Trial name
- PIN'SNP (NCT04207580)
- Testing
- Inclusion and follow up of pediatric patients with an idiopathic nephrotic syndrome,
- Where
- 48 sites in France, Reunion
- Volunteers
- 1,180 people
- Sponsor
- University Hospital, Limoges
Colonic Polyp
Endoscopic Submucosal Dissection (ESD) Versus Endoscopic Mucosal Resection (EMR) for Large Non Pedunculated Colonic Adenomas: a Randomized Comparative Trial
Initially developed in Japan for the treatment of endemic superficial gastric cancers, endoscopic submucosal dissection (ESD) allows resection of pre-neoplastic and neoplastic lesions of the digestive tract into a single…
- Trial name
- RESECT COLON (NCT03962868)
- Testing
- Experimental procedure : ESD, Comparison procedure: WF-piece meal EMR
- Where
- 6 sites in France
- Volunteers
- 360 people
- Sponsor
- University Hospital, Limoges