Clinical trials: sponsored by University Hospital, Limoges
Hepatitis D
DELTA DESCRIBE: the French Collaborative Project
Our global objective is to draw up a photograph of HDV patients over one year in metropolitan France and identify the barriers of screening and care.
- Trial name
- DELTADESCRIBE (NCT05936073)
- Testing
- Patients co-infected HBV/HDV
- Where
- France
- Volunteers
- 734 people
- Sponsor
- University Hospital, Limoges
Chronic Liver Disease
Albumin Modifications as Early Biomarkers of Chronic Liver Diseases
Chronic liver diseases, affecting over 800 million people worldwide, lead to approximately 2 million annual deaths. The need for early, sensitive diagnostic strategies to prevent disease progression and reduce mortality is still…
- Trial name
- MALAHBAR (NCT06318949)
- Testing
- blood sampling
- Where
- 7 sites in France, Guadeloupe
- Volunteers
- 756 people
- Sponsor
- University Hospital, Limoges
Toxicology
Temporal Variation of the Exposure to Pesticides in the Employees of the Limoges University Hospital
In a sample of 300 employees of the Limoges University Hospital, it is proposed to explore the intraindividual and interindividual variability of urinary concentrations of glyphosate and 320 other pesticides.
- Trial name
- VESTAL (NCT06045234)
- Testing
- Urine sampling
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Glioma
Clinical Relevance of Detecting Molecular Abnormalities in Glial Tumor Exosomes
The purpose of this pilot study is that exosomes constitute a more interesting support for analyzes allowing a broader screening of molecular alterations to be carried out with more reliable, more sensitive and more efficient…
- Trial name
- ExoGLIE (NCT06116903)
- Testing
- Blood sampling
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Limoges
Hematological Malignancies
Efficacy of Inhaled Aromatherapy on Nausea and Vomiting in Hematological Malignancies
This project will optimise the management of chemotherapy-induced nausea and vomiting, with improvements in nausea and vomiting scores, quality of life and appetite expected in participants benefiting from the intervention.
- Trial name
- AROM-HEMATO (NCT06150469)
- Testing
- "Blend of ginger and lemon essential oils", "Neutral oil"
- Where
- 4 sites in France
- Volunteers
- 286 people
- Sponsor
- University Hospital, Limoges
Cystic Fibrosis
Determinants of Daily Physical Activity Level in Patients With Cystic Fibrosis - Pilot Study Protocol
The aim of the study is to analyze the determinants (barriers and facilitators) of the daily physical activity level in a population of patients with cystic fibrosis.
- Trial name
- APM (NCT05206097)
- Testing
- Accelerometer
- Where
- 6 sites in France
- Volunteers
- 87 people
- Sponsor
- University Hospital, Limoges
Rectal Tumor, Women
Study of the Prevalence of Sexual Dysfunction in Women After Rectal Cancer Surgery and Analysis of the Impact of a Sexologist Intervention
RectSexQoL is a study aiming at determining the prevalence of female sexual dysfunction after rectal cancer surgery. It has the goal as well to analyse the impact of an intervention given by a sexologist to such patients.
- Conditions
- Rectal Tumor, Women, Sexuality, Life Quality
- Trial name
- RectSexQol (NCT05933122)
- Testing
- sexologist consult, standart of care
- Where
- 6 sites in France
- Volunteers
- 144 people
- Sponsor
- University Hospital, Limoges
Colorectal Cancer Metastatic, Chemotherapy
Study of the Therapeutic Response and Survival of Patients with Metastatic Colorectal Cancer (stage IV) and Treated According to the Guidelines of a Chemosensitivity Test, Oncogramme® (ONCOGRAM)
Currently, chemotherapies are empirically administered to patients treated for colorectal cancer (CRC). Selection is based on the efficacy of a protocol previously determined on the largest number (consensus treatment), the…
- Trial name
- ONCOGRAM (NCT03133273)
- Testing
- Oncogramme®
- Where
- 13 sites in France
- Volunteers
- 256 people
- Sponsor
- University Hospital, Limoges
Cervical Ripening, Pregnancy
Is There an Interest in Repeating the Vaginal Administration of Dinoprostone (Propess®), to Promote Induction of Labor of Pregnant Women at Term?
According perinatal surveys, induction of labor is performed at more than 20% of pregnant women. According to a survey on the trigger practices in France, prostaglandins are widely used to initiate cervical ripening, usually by…
- Trial name
- RE-DINO (NCT02888041)
- Testing
- Dinoprostone, Oxytocine
- Where
- 7 sites in France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Limoges
Stroke Rehabilitation
Walking Ankle isoKinetic Exercise
This study is a multi-center, interventional, experimental, prospective, controlled and randomized study. We propose a reeducation protocol based on an early over-solicitation of the ankle dorsiflexor muscles to promote their…
- Trial name
- WAKE (NCT04800601)
- Testing
- Rehabilitation program 1, Rehabilitation program 2
- Where
- 7 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Limoges
Ventricular Dysfunction, Right, Lung Diseases
Evaluation of the Right Ventricular Systolic Function Using Real-time Three-dimensional Echocardiography in Intensive Care Unit Patients
Right ventricular failure (RVF) is an independent factor of mortality for many pulmonary diseases. Currently, RVF is defined as the incapacity of the RV to maintain the flow without dilating to use the Frank-Starling law (i.e.…
- Conditions
- Ventricular Dysfunction, Right, Lung Diseases, Intensive Care Units
- Trial name
- REA-3D-VD (NCT04222764)
- Testing
- Real-time three-dimensional echocardiography
- Where
- 2 sites in France
- Volunteers
- 341 people
- Sponsor
- University Hospital, Limoges
Pancreatic Stone Protein, Device
Analytical Validation of the abioSCOPE Device With the in Vitro Device (IVD) CAPSULE PSP Test: Comparison of PSP Values Measured With Venous Whole Blood and Those Measured With Arterial Whole Blood
Abionic society has developed a novel point-of-care (POC) platform, the abioSCOPE, and an in vitro diagnostic kit for the quantification of the pancreatic stone protein (PSP) to be analyzed specifically with the abioSCOPE®…
- Trial name
- AB-PSP-006 (NCT05540210)
- Testing
- measurement of PSP
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Limoges
Prolapse, Vaginal
Vaginal Native Tissues Repair for Pelvic Organ Prolapse
The aim of the study is to assess at one year the effectiveness of the vaginal patch plastron in comparison of the anterior colporraphy through a combined definition of success: anatomic and functional.
- Trial name
- TAPP (NCT03875989)
- Testing
- Anterior colporraphy, vaginal patch plastron
- Where
- 9 sites in France
- Volunteers
- 214 people
- Sponsor
- University Hospital, Limoges
Cerebrovascular Accident
Oxygen Consumption in Post-stroke Patients During Various Walking Activities Compared to Healthy Controls
Stroke is major public health issue. The investigators recommend post-stroke patients to practice physical activity. Nevertheless, the recommendations are not widely respected due to the intensity of exercises.
- Trial name
- STROXCO (NCT05477238)
- Testing
- walking tasks
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Scleroderma, Systemic
Pilot Study of Description of Cicatrisation Rates of Digital Ulcers in Systemic Scleroderma
To make an updated inventory of digital ulcer care protocols in scleroderma patients and to specify the French data on monthly healing rates and local care with patients in care centers experience, and thus to know the impact of…
- Trial name
- POPSUD (NCT04319120)
- Testing
- questionnaires online
- Where
- 3 sites in France
- Volunteers
- 78 people
- Sponsor
- University Hospital, Limoges
Aortic Valve Stenosis, Valsartan
Efficacy of Angiotensin Receptor Blocker Following aortIc Valve Intervention for Aortic STenOsis: a Randomized mulTi-cEntric Double-blind Phase II Study
Aortic stenosis (AS) is the most frequent valvular heart disease in Western countries, with increasing prevalence. Recent guidelines recommend aortic valve intervention (surgical aortic valve replacement [SAVR] or transcatheter…
- Conditions
- Aortic Valve Stenosis, Valsartan, Angiotensin Receptor Antagonists, Transcatheter Aortic Valve Replacement
- Trial name
- ARISTOTE (NCT03315832)
- Testing
- Valsartan
- Where
- France
- Sponsor
- University Hospital, Limoges
Sepsis
Analytical Validation of the abioSCOPE Device With a PSP Test: Point-of-Care Precision, Sample Type Comparison and Sample Stability
Abionic SA has developed a novel point-of-care (POC) platform, the abioSCOPE, and an in vitro diagnostic kit for the quantification of the pancreatic stone protein (PSP) to be analyzed specifically with the abioSCOPE® device.
- Trial name
- AB-PSP-005 (NCT04797117)
- Testing
- blood sample
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Limoges
Colorectal Cancer
Diagnostic and Prognosis Value of Circulating DNA for CRC Patients' Surveillance After Curative Treatment
Inspite of curative treatment 30-50% patients with ColoRectal Cancer (CRC) develop tumor relapse during the first 3 years after treatment of the primary tumor.
- Trial name
- ADNCirc (NCT02813928)
- Testing
- ccfDNA analysis
- Where
- 19 sites in France
- Volunteers
- 473 people
- Sponsor
- University Hospital, Limoges
Giant Cell Arteritis in Dependency of Elderly
Pilot Study of the Impact of Giant Cell Arteritis and Its Treatment on the Autonomy of the Elderly in the First Year of Care
Giant cell arteritis is the leading cause of vasculitis in the elderly. No work evaluates its impact on autonomy. At the diagnosis a gerontological evaluation will be carried out including the scores ADL, iADL, MNA, SF 36, SPPB…
- Trial name
- EPACAPA (NCT03961113)
- Testing
- Assessment by questionnaire
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Limoges
Diagnostic Imaging, Newborn
Performance of Lung Ultrasonography for Endotracheal Tube Positioning in Neonates
Lung Ultrasonography (US) has been shown to be effective for verifying endotracheal tube (ETT) position in adults and children but has been less studied in neonates.
- Conditions
- Diagnostic Imaging, Newborn, Intubation, Ultrasonography
- Trial name
- ECHOSI (NCT03818139)
- Testing
- radiography thorax
- Where
- France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Limoges