Clinical trials: sponsored by University Hospital, Limoges
Rheumatism
Assessment of the Psychological Impact of the COVID19 (SARS-CoV-2) Pandemic on Patients With Chronic Inflammatory Rheumatism
Patients with chronic inflammatory rheumatism (RIC) or autoimmune diseases, rheumatoid arthritis and spondyloarthritis, are regularly monitored in consultation as part of a "treat to target" strategy with rapid adaptation of…
- Trial name
- RICOVID19 (NCT04723407)
- Testing
- questionnaires
- Where
- France
- Volunteers
- 950 people
- Sponsor
- University Hospital, Limoges
COVID-19 Infection, Sars-cov-2
Use of Dexmedetomidine in Light to Moderate Sedation in the Patient in the Palliative Situation of a Sars-cov-2 / COVID-19 Infection
The current sars-cov-2 epidemic is responsible for severe respiratory infections leading to end-of-life situations. Dexmedetomidine may be indicated in mild to moderate sedation in palliative patients, due to its pharmacological…
- Conditions
- COVID-19 Infection, Sars-cov-2, Respiratory Failure, Palliative Situation
- Trial name
- PRODEX (NCT04350086)
- Testing
- Treatment with Dexmedetomidine
- Where
- France
- Sponsor
- University Hospital, Limoges
Renal Failure Chronic Requiring Hemodialysis
Pharmacokinetics of an Aminoglycoside in Hemodialysis Patients.
Aminoglycosides are widely used for the treatment of Gram-negative bacilli and Staphylococcus aureus infections because of their effectiveness and low cost.
- Trial name
- DIAMS (NCT01982864)
- Testing
- Gentamicin
- Where
- 2 sites in France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Limoges
Sepsis
Flow Cytometry Analysis of the Reactive Oxygen Species in Immature Granulocytes in Septic Patient
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. Early during sepsis course, immature neutrophils could be found in the bloodstream and may be less efficient than mature…
- Trial name
- SEPSIROS (NCT03846596)
- Testing
- Additional blood tube
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Limoges
Gastroparesis
Feasibility of Endoscopic Pylorotomy in the Treatment of Refractory Gastroparesis, Pilot Study.
Gastroparesis is a common chronic condition, disabling the limited therapeutic resources justifying the exploration of new therapeutic possibilities.
- Trial name
- GASTROPOP (NCT02779920)
- Testing
- per oral pylorotomy
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Limoges
Ventilator-associated Pneumonia, Cardiac Arrests With Shockable Rhythm
Antibiotherapy During Therapeutic Hypothermia to Prevent Infectious Complications
Mild therapeutic hypothermia is currently recommended in management of cardiac arrests with shockable rhythm. In mechanically ventilated patients who were resuscitated after out-of-hospital cardiac arrests, mild therapeutic…
- Conditions
- Ventilator-associated Pneumonia, Cardiac Arrests With Shockable Rhythm, Mild Therapeutic Hypothermia, Preventive Antibiotics
- Trial name
- ANTHARTIC (NCT02186951)
- Testing
- Amoxicillin - clavulanic acid
- Where
- 16 sites in France
- Volunteers
- 197 people
- Sponsor
- University Hospital, Limoges
Coats Disease
Coats Plus Syndrome and LCC Syndrome: Series of 10 Pediatric Cases. Review of Literature and Natural History
Coats plus syndrome is a very rare and serious disease, caused by premature telomere shortening. It is a pediatric, multi-systemic disease, the main features of which are retinal vasculopathy and neurological disorders…
- Trial name
- COATS+ (NCT04089995)
- Testing
- data collection
- Where
- 6 sites in France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Limoges
Corneal Newvessels
Efficacy and Safety Study of Avastin to Treat Neovascularisation of the Cornea
Corneal newvessels may arise from a fan of pathologies, inducing long-standing corneal opacification requiring keratoplasty. These last years, VEGF inhibitors have been designed to reduce newascularization induced by gastric…
- Trial name
- BECONNEC (NCT01501760)
- Testing
- bevacizumab, NaCl
- Where
- 5 sites in France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Limoges
Transplant Recipients With CMV Infection
A French Cohort of Transplant Recipients With CMV Infection : Risk Factors for Antiviral Resistance in the Prophylaxis Era.
Resistance to antivirals is a growing problem in transplantation.that may concerns up to 5% of patients treated for cytomegalovirus (CMV) syndrome or disease in recent per-protocol studies.
- Trial name
- ORPHAVIC (NCT02067169)
- Testing
- CMV Infection
- Where
- 38 sites in France
- Volunteers
- 408 people
- Sponsor
- University Hospital, Limoges
Tissue and Organ Harvesting, Liver Transplantation
Evaluation of Liver Grafts With FibroScan® Before Organ Retrieval in Patients With Brain Death
According to the French Biomedicine Agency annual report on retrieval activities and transplants, 1,164 liver transplants were performed in 2011 and 1,161 in 2012.
- Conditions
- Tissue and Organ Harvesting, Liver Transplantation, Brain Death
- Trial name
- FIBROSCAME (NCT02460250)
- Testing
- Fibroscan
- Where
- 19 sites in France
- Volunteers
- 740 people
- Sponsor
- University Hospital, Limoges
Bacteriology
Dynamic of the Acquisition of Antibiotic Resistance in Integrons in Neonatology Newborns
Antibiotic resistance is a major public health issue as multiresistant bacteria (MRB) are increasing. Among the actions to control resistance, one is an interesting lead: to prevent the emergence of resistant bacteria by limiting…
- Trial name
- DAIR3N (NCT02434679)
- Where
- 5 sites in France
- Volunteers
- 278 people
- Sponsor
- University Hospital, Limoges
Trigeminal Neuralgia
Regional Anesthesia in Refractory Trigeminal Neuralgia: 21 Cases Reported to the Limoges University Hospital
Trigeminal neuralgia is defined according to the third edition of the International Classification of Headache Disorders (ICHD-3) criteria. Chronic pain can have a major impact on the quality of life.
- Trial name
- TRINEB ONE (NCT03669744)
- Testing
- telephone survey
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Limoges
Cirrhosis Renal
Description of the Evolution of Plasma and Urinary Concentrations of Iohexol in a Cirrhotic Patient Population
Background: It is important to accurately assess the glomerular filtration rate (GFR) of patients with liver diseases, particularly cirrhosis, to deliver care and adjust the drugs' posology.
- Trial name
- DFG HEP (NCT03769597)
- Testing
- Iohexol Inj 300 MG/ML
- Where
- France
- Volunteers
- 13 people
- Sponsor
- University Hospital, Limoges
Bones, Tumors
STernectOmy Repair Efficiency of a Ceramic Implant
For the replacement of the sternum, there is no consensus regarding the most appropriate and most effective physiologically material.
- Trial name
- STOIC (NCT02683590)
- Testing
- Ceramic Implant
- Where
- 3 sites in France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Limoges
Gastroparesis
Long-term Results of Per-oral Pyloromyotomy for Refractory Gastroparesis
This is a large multicenter retrospective French cohort conducted in seven French centers that had performed at least five G-POEM procedures at the end of 2017.
- Trial name
- NCT04024709
- Testing
- Gastric Peroral Endoscopic Myotomy
- Where
- 7 sites in France
- Volunteers
- 129 people
- Sponsor
- University Hospital, Limoges
EUS Guided Biliary Drainage
Endoscopic Ultrasound Guided Choledocoduodenostomy With the Lumen Apposing Metal Stent [Axios® Stent]
Endoscopic Ultrasound (EUS) guided biliary drainage is indicated in case of impossibility or failure of classic biliary drainage by endoscopic retrograde cholangio-pancreatography (ERCP).
- Trial name
- NCT04024930
- Where
- 8 sites in France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Limoges
Lung Cancer
Wholebody MRI In Lung Cancer StagiNg
Magnetic Resonnace Imaging (MRI) and Positron Emission Tomography (PET) can be both used in detection of nodes in patients with cell lung cancer (NSCLC).
- Trial name
- WISLON (NCT02716051)
- Testing
- MRI, PET
- Where
- France
- Volunteers
- 36 people
- Sponsor
- University Hospital, Limoges
Cerebral Toxoplasmosis, AIDS
Cerebral Toxoplasmosis and AIDS
With a HIV incidence much higher in the DFA than in European French territory, this disease is a major public health problem in these areas, especially in French Guiana.
- Trial name
- TOXODFA (NCT00803621)
- Testing
- Toxoplasma PCR assay
- Where
- 5 sites in France
- Volunteers
- 46 people
- Sponsor
- University Hospital, Limoges
Infertility
Uterine Allotransplantations Using Uterine Grafts From Brain-dead Female Donors
Uterus transplantation may enable women with uterine factor infertility to become pregnant and give birth. This study will explore the feasibility of a uterine transplant and eight subjects will undergo deceased donor uterine…
- Trial name
- ATU (NCT02637674)
- Testing
- Uterus Transplant
- Where
- 4 sites in France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Limoges
Epilepsy
Epilepsy-Associated Stigma
Few data about epilepsy-associated stigma in France are available. The only study we have found showed that in France 66% of people with epilepsy felt stigmatized by their condition and are often single, compared with the other…
- Trial name
- EPISTIGMA (NCT01374204)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Limoges