Clinical trials: sponsored by University Hospital, Montpellier
Developmental Coordination Disorder
Effectiveness of the COOP Group Approach for Children With Developmental Coordination Disorder (DCD)
Developmental Coordination Disorder (DCD) is a neurodevelopmental disorder that causes difficulty in motor coordination both in their learning and in their execution. This disorder affects about 5% of school-age children.
- Trial name
- ECOOPG (NCT05231486)
- Testing
- Cognitive Orientation to daily Occupational Performance
- Where
- France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Montpellier
Ophthalmological Disorder
Effect of Binocular Treatment Using a Dichoptic Reading Application in Children With Convergence Insufficiency.
Convergence insufficiency is a common disorder of binocular vision that can appear as early as childhood after visual effort, and is often associated with a variety of symptoms such as eyestrain, headaches, blurred vision and…
- Trial name
- ALEDICE (NCT06465615)
- Testing
- Self-education with dichoptic reading on tablet, Conventional orthoptic rehabilitation
- Volunteers
- 26 people
- Sponsor
- University Hospital, Montpellier
Child Psychiatry, Adolescent
Cognitive and Behavioral Therapy in School Refusal
Anxious school refusal (ASR) is a common disorder which concerns more and more adolescents who are at worse completely absent from school.
- Conditions
- Child Psychiatry, Adolescent, Anxious School Refusal, Cognitive Behavioral Therapy
- Trial name
- RSA-Coll (NCT04559633)
- Testing
- cognitive and behavioral therapy (CBT)
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Montpellier
Total Knee Arthroplasty, Chronic Postoperative Pain
Postoperative Painful Chronicization After Knee Replacement Surgery : Exploratory Study of BDNF's Kinetics
Chronic pain is an extremely disabling disease. It is a major public health problem due to the lack of effective therapy. Chronic postoperative pain (CPOP) is defined by a painful symptomatology in the operated area unrelated to…
- Trial name
- KNEE BDNF (NCT04604847)
- Testing
- blood test
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Merkel Cell Carcinoma
Identification and Characterization of Circulating Tumor Cells Before and After Treatment (Surgery and Radiotherapy) in a Cohort of Patients Treated for Resectable Stage I-III Merkel Cell Carcinoma
The goal of this prospective observational study is to evaluate the presence of circulating tumoral cells in patients over 18 with a stage I-III resectable Merkel cell carcinoma after the initial therapeutic sequence of surgery…
- Trial name
- MERCCALIBI (NCT06448611)
- Testing
- Blood Test
- Volunteers
- 25 people
- Sponsor
- University Hospital, Montpellier
Newborns, Neonatology
Interest of Peripheral Venous Catheter Insertion Using a Micro-guide in Neonatology
Peripheral venous catheterization represents the preferential option for term or preterm infant care in order to start drug treatment or hydration, or perform anesthesia.
- Conditions
- Newborns, Neonatology, Intensive Care
- Trial name
- EASYCATH (NCT04984967)
- Testing
- Insertion of peripheral venous catheter with micro-guide, Classic insertion of peripheral venous catheter, without micro-guide
- Where
- France
- Volunteers
- 116 people
- Sponsor
- University Hospital, Montpellier
Respiratory Complication
Trial to Evaluate an Optimization Procedure of Alveolar Recruitment During Transport Performed by Nurse Anesthetists in Intensive Care
Intra hospital transport of ICU patients is still at high risk of respiratory complications.We propose to determine if endotracheal tube clamping prior to disconnect ventilator allows to avoid oxygenation decrease.
- Trial name
- ESCORTE (NCT04159220)
- Testing
- Clamping of the ventilator endotracheal tube
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Montpellier
Women (Between 18 to 50 Years Old), Sacro-iliac Joints
Incidence of MRI Sacro-Iliac Joint Anomalies in Young Women
Prospective multicenter study assessing the incidence of inflammatory and structural lesions seen on MRI of the SI joints in a consecutive population of women aged 18-50 years old.
- Conditions
- Women (Between 18 to 50 Years Old), Sacro-iliac Joints, Inflammatory Lesions, Structural Lesions
- Trial name
- MISIA (NCT02956824)
- Testing
- Standard care
- Where
- France
- Volunteers
- 512 people
- Sponsor
- University Hospital, Montpellier
Respiratory Failure
Effects of High-flow Oxygen Therapy and Non-invasive Ventilation on Lung Volumes and on Upper Airway
Respiratory failure is the most frequent organ failure and cause for admission in the Intensive Care Unit (ICU) . It is a severe complication with an ICU mortality ranged from 31% to 33%.
- Trial name
- HONIVAH (NCT05643911)
- Testing
- HFNC, NIV
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Montpellier
Reversible Cerebral Vasoconstriction Syndrome
Triggers And Risk Factors to Develop a Reversible Cerebral Vasoconstriction Syndrome
This study will be the first to evaluate the role played by potential precipitating factors and risk factors in Reversible Cerebral Vasoconstriction Syndrome (RCVS) through of prospective selection of carefully characterised…
- Trial name
- TARDIS (NCT04179383)
- Testing
- Constitution of a biobank
- Where
- France
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Tracheotomised Children, Anxiety of Parents
Parental Mental Health After Tracheostomy in Early Childhood
To assess the prevalence of anxiety / depression in post- hospital for parents (mothers and fathers) of children with tracheotomy before the age of 1 year between 2000 and 2012.
- Conditions
- Tracheotomised Children, Anxiety of Parents, Depression of Parents
- Trial name
- TRACH (NCT02884570)
- Testing
- Auto-Questionnaires
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Respiratory Distress Syndrom, High Flow Nasal Cannula
Efficacy and Tolerance of High Flow Nasal Cannula for Respiratory Distress Syndrom in Late Preterms (34-36 Weeks)
The main objective of the study is to gather preliminary data on the effectiveness of High Flow Nasal canula (HFNC), provided since the delivery room, for ventilatory support in newborns of 34-36 weeks with moderate respiratory…
- Trial name
- PRIMAIR (NCT02958488)
- Testing
- High Flow Nasal Cannula
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Sleepwalking
Functional Imagery of Sleepwalking
Sleepwalking (also called somnambulism) is a disorder in which only SWS is disrupted. This NREM parasomnia is characterized by inappropriate motor behaviors, usually initiated during arousal from SWS, that induce psychological…
- Trial name
- NCT02844231
- Testing
- Single-photon emission computed tomography
- Where
- France
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Narcolepsy 1, Kleine-Levin Syndrome
Microglial Activation in Narcolepsy Type 1 and Kleine-Levin Syndrome: Positron Emission Tomography (PET) Study in [18F] DPA-714
Type 1 narcolepsy (NT1) is a chronic sleep disorder caused by the selective and irreversible loss of neurons from the hypothalamus, which synthesizes a neurotransmitter: hypocretin (Hcrt) / orexin.
- Trial name
- NARCOGLIE (NCT03754348)
- Testing
- PET scan with tracer injection [18F] DPA-714
- Where
- France
- Volunteers
- 78 people
- Sponsor
- University Hospital, Montpellier
Breast Cancer
Value of Tomosynthesis in Breast Lesion Characterization and Breast Cancer Staging
Study Rationale: an accurate breast cancer staging has a great impact in the management of a breast cancer. MRI is considered as the most sensible exam for this staging.
- Trial name
- NCT01881880
- Testing
- Bilateral mammography with Tomosynthesis
- Where
- 6 sites in France
- Volunteers
- 424 people
- Sponsor
- University Hospital, Montpellier
Acute Ichemic Stroke, Brain Ischemia
Multimodal Investigation of Intracranial Clot Environment
Analysis of peri clot blood collected at the acute phase of stroke in order to understand physiopathological mechanisms involved in the cerebrovascular damage
- Trial name
- MISO (NCT04421326)
- Testing
- Analysis of the clot
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Autism Spectrum Disorder
Intestinal Dysbiosis and BBB Integrity in Autism
Autism Spectrum Disorder (ASD) is characterised by an impairment of social interactions and communication, associated with repetitive behaviour and restrictive interests.
- Trial name
- LEDA (NCT04321915)
- Testing
- Analysis of intestinal microbiota in autism spectrum desorder, Analysis of neuroinflammation markers in autism spectrum desorder
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Degenerative Disc Disease, Inflammation
Evaluating the Efficacy of Para-discal Infiltration in Patients With Lateralized MODIC 1 Inflammatory Disc Disease
Degenerative disc disease (DDD) is a major cause of chronic low back pain (> 40%). It can be defined by specific magnetic resonance imaging (MRI) features, with a strong correlation between pain and the inflammatory aspect of the…
- Conditions
- Degenerative Disc Disease, Inflammation, Low Back Pain
- Trial name
- IPAD (NCT05615597)
- Testing
- Para-discal injection of corticoid
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Ischemic Stroke, Migraine
Sensitivity to Acute Cerebral Ischemia in Migrainers
Sensitivity to Acute Middle cerebral or intracranial Carotid artery Occlusion in MIGrainers (SMCO-MIG) is a prospective multi-center study to determine if migraine induces a faster infarct growth as assessed by initial multimodal…
- Conditions
- Ischemic Stroke, Migraine, Migraine With Aura
- Trial name
- SAMCO-MIG (NCT03301441)
- Testing
- questionnaire ef-ID Migraine
- Where
- France
- Volunteers
- 605 people
- Sponsor
- University Hospital, Montpellier
Acute Ischemic Stroke
Evaluation of Functional Recovery of Patients With Acute Ischemic Stroke Treated by Thrombectomy
The management of cerebral infarctions (CI) is a real public health issue. The French National Authority for Health recommends Mechanical Thrombectomy (MT) either in combination with Intravenous Thrombolysis (IVT), or alone…
- Trial name
- EPIC (NCT04916782)
- Testing
- Quality of life Questionnaire
- Where
- France
- Volunteers
- 540 people
- Sponsor
- University Hospital, Montpellier
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