Clinical trials: sponsored by University Hospital, Montpellier
Idiopathic Intracranial Hypertension
Biomarkers in the Etiology of Idiopathic Intracranial Hypertension
Idiopathic intracranial hypertension (IIH) is a condition characterized by an increase in intracranial pressure (ICP), papilledema with a risk of permanent visual loss, and severe headaches that profoundly affect quality of life.
- Trial name
- BEHIND (NCT06059703)
- Testing
- Blood punction, Central blood sampling, Intracranial pressure measurement
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Hearing Loss
Telemonitoring in Cochlear Implant Patient Care
Following a sufficient delay after the cochlear implantation and initial implant activation, the patient will return to the hospital for follow-up visits for equipment maintenance and auditory performance evaluation only once per…
- Trial name
- EMPSICOT (NCT05566353)
- Testing
- Remote Check
- Where
- France
- Volunteers
- 78 people
- Sponsor
- University Hospital, Montpellier
Psychogenic Dystonia
Heart Rate Variability Biofeedback Training in Psychogenic Disorders
To study whether Heart Rate Variability (HRV) biofeedback training can improve abnormal head posture and painful symptomatology in patients with "cervical dystonia" not selected for DBS after extensive screening in a specialized…
- Trial name
- ECoDys (NCT04777825)
- Testing
- Heart rate variability biofeedback training (Symbiocenter), psychoeducation session
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Montpellier
Autism Spectrum Disorders
ELENA Cohort: A Long-term Longitudinal Study in a Pediatric Sample With Autism Spectrum Disorders
The objective of the ELENA French Cohort is to study the developmental trajectories of children and adolescents with ASD and their risk or protective associated factors.
- Trial name
- ELENA (NCT02625116)
- Where
- France
- Volunteers
- 919 people
- Sponsor
- University Hospital, Montpellier
Restless Legs Syndrome
Gut Microbiota and Bacterial Translocation in Restless Legs Syndrome
Restless Legs Syndrome (RLS) is a common neurological sensorimotor disorder defined by an urge to move the legs when at rest that increase in the evening and at night.
- Trial name
- RLS-BIOT (NCT05985421)
- Testing
- Fecal collection, Blood sampling, Polysomnography
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Community-acquired Pneumonia, Child, Only
Stopping Pneumonia Antibiotherapy Regimen Early
The hypothesis for this trial is that an antibiotic strategy for the management of non-severe community-acquired alveolar pneumonia in children aged 3 to 59 months, including amoxicillin 80-100 mg/kg/day for at least 3 days in…
- Trial name
- SPARE (NCT06291012)
- Testing
- Quick response: Amoxicillin for 3 days, Delayed response: Amoxicillin for 5 days, Quick response: Amoxicillin for 5 days
- Where
- France
- Volunteers
- 1,100 people
- Sponsor
- University Hospital, Montpellier
Autism Spectrum Disorder
Prevalence and Healthcare Consumption of ASD Patients Using French Medico-administrative Data
Autism Spectrum Disorder (ASD) is one of the neurodevelopmental disorders described in the DSM5 (American Psychiatric Association, 2013).
- Trial name
- ECO-TSA (NCT06409728)
- Where
- 2 sites in France
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Active Tuberculosis, Latent Tuberculosis
COMPArison of Screening Strategies for Active TuBerculosis (COMPASS-TB)
The study is an evaluation of the diagnostic performance of different tests and their association in order to confirm or exclude active tuberculosis.
- Trial name
- COMPASS-TB (NCT06408129)
- Where
- France
- Volunteers
- 580 people
- Sponsor
- University Hospital, Montpellier
Pregnancy
Prevalence of Psychiatric Disorders During Pregnancy at 2nd Trimester Ultrasound: a Feasibility Study in the General Population
Young women represent a population at risk of psychiatric disorders, the first signs of which often appear between the ages of 15 and 25. Psychiatric disorders are a major source of disability and healthcare costs.
- Trial name
- GROUP (NCT06297252)
- Testing
- standardized clinical psychiatric evaluations, self-administered psychiatric questionnaire assessments, blood sampling
- Where
- 2 sites in France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Restless Legs Syndrome
Executive Dysfunction in Restless Legs Syndrome: Clinical Correlates and Outcome After Therapeutic Management
Restless leg syndrome (RLS) is a common neurological disorder whose diagnosis is only clinical. The efficacy of dopaminergic agents in improvement of sensorimotor symptoms advance the hypothesis that altered dopaminergic…
- Trial name
- NCT01823354
- Testing
- Polysomnography, Clinical Scales, Assessment of executive functions
- Where
- 2 sites in France
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Unstable Angina
Incidence, Clinical Characteristics and Outcomes of Unstable Angina in the contempoRary Area.
The study aims to evaluate clinical characteristics and prognostic of a contemporary population of patients with UA defined using T hs-cTn measurements The study includes all patients admitted in 2 French university centers with…
- Trial name
- ICAR (NCT06378333)
- Testing
- patients who underwent coronary angiography
- Where
- France
- Volunteers
- 210 people
- Sponsor
- University Hospital, Montpellier
Perineum; Tear, Traumatic, Anal Tear
Perineal Trauma After Jet Ski Accidents and Long-term Functional Outcomes Results
French multicentric retrospective cohort study including patients who underwent an ano-perineal trauma following a personal watercraft/jet-ski accident and that were treated in France from January 2017 to December 2023.
- Conditions
- Perineum; Tear, Traumatic, Anal Tear, Anal Incontinence
- Trial name
- TP-JET (NCT06368284)
- Testing
- Patients who experienced an ano-perineal trauma following a PWC/Jet-Ski accident
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Chronic Heart Failure
Impact of a Letter Encouraging Pneumococcal Vaccination on the 1-year Vaccination Rate in Heart Failure Patients With a Primary Care Physician
Heart failure affects more than 1.5 million people in France, resulting in over 70,000 deaths and more than 165,000 hospitalizations each year.
- Trial name
- NCT06360315
- Testing
- Incentive letter for pneumococcal vaccination to the patient and to the GP
- Where
- France
- Volunteers
- 12,000 people
- Sponsor
- University Hospital, Montpellier
Juvenile and Adolescent Idiopathic Scoliosis
Preoperative Yoga and Meditation for Pediatric Idiopathic Scoliosis Surgery
This study has to purpose Yoga and Meditation before surgery for idiopathic scoliosis. Protocol's observance will tell the investigators if it is feasible and appropriate in a University hospital center.
- Trial name
- YOMEPOP (NCT05805670)
- Testing
- Yoga and Mindfulness
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Autism Spectrum Disorder, Mental Retardation
Fragility Assessment in Adults With ADHD and Mental Retardation
Frailty is a age dependent physiological state of vulnerability. Frailty is screened by the phenotypic model (5 clinical criteria) or the cumulative model (various clinical and biological criteria).
- Trial name
- EFAAR (NCT02791321)
- Testing
- ADS severity, Adaptative and intellectual functioning, Psychiatric and somatic comorbidities
- Where
- France
- Volunteers
- 63 people
- Sponsor
- University Hospital, Montpellier
Severe Infection, Severe Immune Deficiency
Systematic Screening for Primary Immunodeficiencies in Patients Admitted for Severe Infection in Pediatric Intensive Care Unit
Severe infections in pediatric intensive care unit are not uncommon. Historically, the diagnosis of hereditary (primary) immune deficiency required a combination of recurrent clinical signs and biological stigmas.
- Trial name
- SPYSI (NCT04990908)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Orthopedic Equine Varus Deformity
Talonavicular Arthrodesis and Surgical Treatment of Ankle and Varus Foot
This study should refine our surgical indications and to establish a decision tree of medical and surgical treatment of this common and troublesome strain functionally which is equino-varus.
- Trial name
- talobot (NCT02790346)
- Testing
- arthrodesis talonavicular, tendon gestures
- Where
- France
- Volunteers
- 33 people
- Sponsor
- University Hospital, Montpellier
Depression
Behavioral Self-activation and Virtual Reality in Depression
Depression is a major handicap in daily life and is often treated by behavioral activation (CA), including the Brief Behavioral Activation Treatment for Depression (BATD).The CA principle is to set up activities, in keeping with…
- Trial name
- DEPREVACT (NCT03621488)
- Testing
- Efficacy of Behavioral Self-Activation with virtual reality, Efficacy of Behavioral Self-Activation without virtual reality
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Montpellier
Crohn's Disease
Endoscopic Relapse Risks Evaluation After Ileocolic Resection for Crohn's Disease
Aim of the study: To evaluate risk factors of endoscopic relapse after ileocolic resection in a cohort of Crohn's disease patients treated with anti-TNF agents.
- Trial name
- RIC-1 (NCT06299631)
- Testing
- Ileocolic resection
- Where
- France
- Volunteers
- 133 people
- Sponsor
- University Hospital, Montpellier
Suicide, Depression
Plasma Beta-endorphin Levels and Suicidal Behavior
It is an interventional research, monocentric, which involves only minimal risks and constraints. Psychological pain is closely associated with suicidal ideation (SI) and suicidal behavior, regardless of the severity of the…
- Conditions
- Suicide, Depression, Beta Endorphin
- Trial name
- BEST (NCT06291467)
- Testing
- Blood samples, questionnaires
- Where
- France
- Volunteers
- 104 people
- Sponsor
- University Hospital, Montpellier
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