Clinical trials: sponsored by University Hospital, Montpellier
Fibrosis, Liver
Screening for Chronic Liver Diseases in General Population
Improving the care of patients with liver diseases in primary care and will allow patients with chronic liver disease to benefit from a course appropriate care.
- Trial name
- HEPGEN (NCT06366425)
- Testing
- Blood sample then fibroscan
- Where
- France
- Volunteers
- 260 people
- Sponsor
- University Hospital, Montpellier
Miscarriage
Hysteroscopy vs. Endouterine Aspiration in the Management of Trophoblastic Retention
Introduction: Incomplete early miscarriage is defined as early miscarriage with persistent intrauterine material on ultrasound. Intrauterine retention of trophoblastic debris is not an uncommon phenomenon.
- Trial name
- HARET (NCT05789940)
- Testing
- hysteroscopy, Aspiration
- Where
- 4 sites in France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Montpellier
Alcohol Use Disorder, Addiction
Motivational Interviews Post Hospitalisation on Maintaining AbstiNence for 1 Year après le Sevrage en Alcool
The aim of this clinical study is to evaluate the efficacy of reinforced inpatient aftercare versus usual care on the percentage of days of abstinence during the first year following withdrawal in adults with alcohol use…
- Conditions
- Alcohol Use Disorder, Addiction, Alcohol Withdrawal, Motivational Interviews
- Trial name
- IMMANENCE (NCT06618755)
- Testing
- Experimental group : PSH (usual care) with motivational interviewing
- Where
- France
- Volunteers
- 104 people
- Sponsor
- University Hospital, Montpellier
Long QT Syndrome, Brugada Syndrome
Healthy-related Quality of Life and Physical Activity of Children With Cardiac Malformations
The QUALIMYORYTHM trial is a multicentre controlled study, aiming to assess health-related quality of life (HRQoL) of 107 children aged 6 to 18 years old with inherited cardiac arrhythmia (long QT syndrome, Brugada syndrome…
- Conditions
- Long QT Syndrome, Brugada Syndrome, Catecholaminergic Polymorphic Ventricular Tachycardia, Arrhythmogenic Right Ventricular Dysplasia
- Trial name
- QUALIMYORYTHM (NCT04712136)
- Testing
- MRI
- Where
- France
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Pregnancy, Twin
Prospective Twin Pregnancy Cohort at Montpellier University Hospital
This prospective observational cohort study aims to investigate the impact of the maternal and early-life exposome on neonatal and early childhood health outcomes in twin pregnancies followed at University Hospital of Montpellier…
- Trial name
- COGEM (NCT07408973)
- Testing
- Biological samples from the mother, Biological samples from the twins
- Volunteers
- 360 people
- Sponsor
- University Hospital, Montpellier
Endometriosis
The Developmental Origins of Endometriosis
Introduction: Endometriosis is a common pathology affecting one in 10 women, characterized by the ectopic development of endometrium, which can cause pain and/or infertility.
- Trial name
- ENDOHaD (NCT05951452)
- Testing
- Blood samples for testosterone and SHBG measurements, Saliva samples for oxytocin measurements
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Montpellier
Oncology
New Biomarkers in Pancreatic Cancer Using EXPEL Concept
The investigators recently engineered a novel biomarker discovery approach that is non-destructive and fully compatible with OMICS profiling as well as routine clinical procedures (5).
- Trial name
- PANEXPEL (NCT03791073)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Obstetrical Brachial Plexus Palsy
Study of the Biological Function of Muscle Satellite Cells From Patients With Obstetric Brachial Plexus Palsy
The purpose of this prospective work is to study the consequences of obstetrical brachial plexus paralysis on the rotator muscles of the shoulder.
- Trial name
- SCOPE (NCT05403034)
- Testing
- Muscle biopsy
- Where
- France
- Volunteers
- 8 people
- Sponsor
- University Hospital, Montpellier
Liver Injury, Secondary to Immune Checkpoint Inhibitors
Prospective Cohort of Immune Checkpoint Inhibitor-induced Hepatitis
Background and Study Rationale Immune checkpoint inhibitors (ICI) are a breakthrough cancer treatment that boosts the immune system to fight tumors.
- Conditions
- Liver Injury, Secondary to Immune Checkpoint Inhibitors, Cancer Patients
- Trial name
- CO-CHILI (NCT06864481)
- Testing
- Blood samples
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Montpellier
Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis Non-invasive Ventilation Exchange
The median survival of patients with amyotrophic lateral sclerosis (ALS) is 3 to 5 years and mortality is mainly related to respiratory failure.
- Trial name
- ANEX (NCT05837507)
- Testing
- Telerehabilitation solution (m-Rehab), Usual management including NIV.
- Where
- 2 sites in France
- Volunteers
- 43 people
- Sponsor
- University Hospital, Montpellier
Asthma
CT Air-trapping for the Early Identification of Benralizumab Responders Among Eosinophilic Asthma Patients
BenraliScan aims to obtain thoracic computed tomography imaging data to predict the future level of patient response to a monoclonal antibody.
- Trial name
- BenraliScan (NCT03976310)
- Testing
- 48 weeks of Benralizumab, Computed tomography
- Where
- 2 sites in France
- Volunteers
- 59 people
- Sponsor
- University Hospital, Montpellier
Cardiac Surgery, Transfusion
Transfusion Savings in Heart Surgery: Impact of Individual Strategy by Erythropoietin and Metabolic Adjustment (ScvO2)
Preoperative anemia, bleeding and transfusions have been recognized as a "Deadly triad" in cardiac surgery associated with an increased morbidity,mortality, and costs related.
- Conditions
- Cardiac Surgery, Transfusion, Perioperative Anemia
- Trial name
- BLOOCOST (NCT04141631)
- Testing
- EPO (600UI/Kg, sub-cutaneous) and Ferric Carboxymaltose (FCM) (20 mg/kg in 250 mL of saline solution 0.9% over 15 min)
- Where
- France
- Volunteers
- 128 people
- Sponsor
- University Hospital, Montpellier
Healthy Volunteers, Arthritis, Rheumatoid
Characterization of Breg Cells
Recently, it has been shown that B cells could also have regulatory functions through the secretion of interleukin 10 (IL-10). They are called the B regulatory cells (Breg).
- Trial name
- Breg (NCT02615951)
- Testing
- blood sampling
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Eustachian Tube Disorder
Long Term Evaluation of Tubal Expansion on Obstructive Dysfunctions of Eustachian Tube
The study aim is to evaluate the tubal score on patients who suffer from obstructive dysfunction of eustachian tube before and after the eustachian tube dilatation.
- Trial name
- NCT02123277
- Testing
- Balloon catheter for the Eustachian tube
- Where
- France
- Volunteers
- 31 people
- Sponsor
- University Hospital, Montpellier
Endocrinology, Type 2 Diabetes
Interest of FSL 2 in Recently Diagnosed Type 2 Diabetic Patients
Therapeutic patient education (TPE) is a key element in the management of people living with type 2 diabetes. The benefit of therapeutic education (TPE) has been clearly established on glycaemic control.
- Trial name
- FREEDIA (NCT05676593)
- Testing
- Freestyle Libre 2, Therapeutic education
- Where
- France
- Volunteers
- 27 people
- Sponsor
- University Hospital, Montpellier
Bronchiolitis
Comparison Between 2l vs 3l in HFNC During the Initial Management of Severe Bronchiolitis in Infants
The purpose of the study is to evaluate prospectively the clinical benefits of 2 different flow with High flow nasal canula (HFNC: 2l/kg/min) versus (HFNC: 2l/kg/min) in the initial management of bronchiolitis in infants.
- Trial name
- TRAMONTANE2 (NCT02824744)
- Testing
- treatment by 2l/min/kg in High Flow Nasal cannula (HFNC), treatment by 3l/min/kg in High Flow Nasal cannula (HFNC)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Pregnancy
PIEB-PCEA Versus CEI-PCEA for Labor Analgesia in Nulliparous
Epidural analgesia still have an impact on obstetric outcomes and especially on instrumented delivery rates. To assess the best maintainance regimen of epidural analgesia during labor the investigators plan to include 300…
- Trial name
- PIEB (NCT01856166)
- Testing
- Release analgesia by CADD SMITHS PCEA pump, Release analgesia by CADD SMITHS PIEB pump, Levobupivacaine
- Where
- 4 sites in France
- Volunteers
- 304 people
- Sponsor
- University Hospital, Montpellier
Obesity, Ventilation
Non-invasive Ventilation Following Extubation (Prophylactic) to Prevent Extubation Failure in Critically Obese Patients
Mechanical ventilation is the first artificial support used in intensive care. After a period of invasive mechanical ventilation, patients should be separated from the ventilator (weaning period of mechanical ventilation).
- Conditions
- Obesity, Ventilation, Intensive Care Unit
- Trial name
- EXTUB-OBESE (NCT04014920)
- Testing
- Oxygen group, NIV Group
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Montpellier
Gonarthrosis
Prospective Cohort Study Evaluating a Thermal Spa Programme in Symptomatic Knee Osteoarthritis
Knee osteoarthritis is a common cause of pain, functional limitation, and reduced quality of life in older adults. Thermal spa treatment is widely used as a non-pharmacological intervention for the management of osteoarthritis…
- Trial name
- THERMOG (NCT07534189)
- Testing
- X-sens sensor, Transcriptomic, Self-questionnaire
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Necrotizing Enterolitis
NIRS and Doppler to Predict NEC in Risk Neonates
The main objective is to evaluate the interest of cerebro-splanchnic oxygenation ratio (CSOR) for early diagnosis of necrotizing enterocolitis (NEC) in neonates with rectal bleeding and/or abdominal distension.
- Trial name
- NeoNIRS (NCT01833000)
- Testing
- Cerebral and splanchnic ear infrared spectroscopy (NIRS) and mesenteric Doppler
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Montpellier
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.