Clinical trials: sponsored by University Hospital, Montpellier
Myocardial Infarction, Acute
COLchicine to Prevent Sympathetic Denervation After an Acute Myocardial Infarction
This study evaluates the benefit of colchicine on induced denervation after myocardial infarction. Patients who have suffered a documented De Novo myocardial infarction and completed a revascularization procedure will receive…
- Trial name
- COLD-MI (NCT04420624)
- Testing
- Colchicine
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Montpellier
Osteoarthritis
A Study Evaluating the Efficacy of a Single Injection Autologous Adipose Derived Mesenchymal Stromal Cells in Patients With Knee Osteoarthritis
ASCs will be administered via intra-articular use into the knee joint affected by OA where they are expected to exert their therapeutic effects.
- Trial name
- ADIPOA-2 (NCT02838069)
- Testing
- Injection (2x106 ASC/5ml)., Injection (10x106 ASC/5ml).
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Chronic Post Stroke Individuals
Recovering Arm Function in Chronic Post-stroke Patients Using Combined HD-tDCS and Virtual Reality Therapy
The study aims to determine the added value of combining high-definition transcranial direct current stimulation (HD-tDCS) in a rehabilitation program based on virtual reality therapy (VRT) to potentiate the effects on…
- Trial name
- ReArm (NCT04291573)
- Testing
- HD-tDCS
- Where
- France
- Volunteers
- 58 people
- Sponsor
- University Hospital, Montpellier
Balanced Chromosomal Translocation
Breakpoint Analysis of de Novo Apparently Balanced Chromosomal Translocations
For every child with developmental delay, the investigators do a constitutional karyotype. This karyotype can reveal an apparently balanced chromosomal rearrangement (no visible loss or gain of genetic material), such as a…
- Trial name
- NCT01826708
- Testing
- Identification of breakpoints
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Montpellier
Acute Coronary Syndrome, Continuous Glucose Measurement
Predictive Value of Glycemic Parameters Measured With the FSL Pro iQ During ACS
Disorders of glycemic regulation are common in patients hospitalized for acute coronary syndrome (ACS). Abnormal glycaemia is observed in 50% of cases, in 30-40% diabetes, and in 25-35% fasting hyperglycaemia or glucose…
- Conditions
- Acute Coronary Syndrome, Continuous Glucose Measurement, Glycemic Variability, Cardiovascular Event
- Trial name
- FREESCA (NCT06014112)
- Testing
- Freestyle Libre Pro iQ
- Where
- 9 sites in France
- Volunteers
- 850 people
- Sponsor
- University Hospital, Montpellier
Ankylosing Spondylitis
Modeling Spinal Mobility in Ankylosing Spondylitis: Towards New Telekinetic Biomarkers
Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease that mainly affects the spine and pelvis in its axial form.
- Trial name
- TELESPA (NCT05570656)
- Testing
- XSENS-Awinda
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Obstructive Sleep Apnea Syndrome
m-Rehab OSA : Impact of a Telerehabilitation Program Associated With CPAP on Severity Markers of Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea syndrome (OSA) is a common condition associated with major repercussions such as excessive daytime sleepiness and impaired quality of life as well as metabolic and cardiovascular complications.
- Trial name
- mRehabOSA (NCT05049928)
- Testing
- Telerehabilitation solution (m-Rehab)
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Montpellier
Low Back Pain
Pilot Study of Vagal Stimulation in Chronic Low Back Pain
Low back pain is a major public health problem. It is the leading cause of disability in the world. The factors that lead to chronicity of low back pain are multi-factorial and are essentially represented by psychosocial factors…
- Trial name
- VALOM (NCT05639270)
- Testing
- use of an auricular electrode
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Aortic Stenosis, Non-rheumatic
Balloon Aortic Valvuloplasty Performed Without Heparin to Decrease Vascular and Bleeding Complications of the Procedure
To assess if the non use of heparin sodium during balloon aortic valvuloplasty reduces serious complications due to the procedure, by decreasing the rate of vascular and hemorrhagic complications without increasing the rate of…
- Trial name
- HEPAVALV (NCT01823393)
- Testing
- Heparin, NaCl
- Where
- France
- Volunteers
- 94 people
- Sponsor
- University Hospital, Montpellier
Chronic Inflammatory Rheumatism
COVID-19 in Rheumatic Inflammatory Diseases Under Immuno-suppressive Drugs
Accurate knowledge of the humoral immune responses induced by SARS-CoV-2 in patients undergoing immunosuppressive therapy is essential to guide recommendations for infected patients and for vaccination policy for uninfected…
- Trial name
- COVIDRIC-2 (NCT04530682)
- Testing
- Biological samples
- Where
- France
- Volunteers
- 163 people
- Sponsor
- University Hospital, Montpellier
Monogenic Diseases
NIPD of CFTC by WGA Coupled to Mini-exome Sequencing
The purprose of this study is to develop a single test based on circulating fetal trophoblastic cells (CFTC) analysis from maternal blood, searching for the familial mutation for a wide range of monogenic diseases.
- Trial name
- DIAFEXOME (NCT03743948)
- Testing
- Non invasive prenatal diagnosis
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
COPD Exacerbation
Eosinophil-driven Corticotherapy for Patients Hospitalized for COPD Exacerbation
The primary objective of this study is to compare treatment failure rates between a group of eosinophilic (eosinophilia > 2% on day 1 of hospitalization) patients hospitalised for a COPD exacerbation treated via corticotherapy…
- Trial name
- eo-Drive (NCT04234360)
- Testing
- 5 days of systemic corticotherapy (prednisone)
- Where
- 18 sites in France
- Volunteers
- 182 people
- Sponsor
- University Hospital, Montpellier
Resident of Languedoc-roussillon, Carrying a Chronic Wound
Medico-economic Evaluation of a Project of Wounds by a Remote Network
Estimate in 6 months the impact of the telemedicine on the cure rate of the chronic wounds compared with the usual care(with or without CICAT-LR Network).
- Trial name
- DOMOPLAIES (NCT02545374)
- Testing
- Telemedicine, Control
- Where
- France
- Volunteers
- 193 people
- Sponsor
- University Hospital, Montpellier
Systemic Sclerosis
Assessment of Nutritional Status in Systemic Sclerosis
The main theme of the cohort of systemic sclerosis (SSc) patients is the determination of nutritional status, its evolution and the evaluation of its management in patients with scleroderma.
- Trial name
- NUTRISCLER (NCT04301596)
- Testing
- Collection of data
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Drug Hypersensitivity
Drug Provocation Test (DPT) to Paracetamol
Background : Paracetamol (acetaminophen) drug hypersensitivity reactions (DHR) are oonfirmed in about 10% of alleged cases. The diagnosis is made via an empirical drug provocation test (DPT).
- Trial name
- Paracetamol (NCT03771118)
- Where
- France
- Volunteers
- 498 people
- Sponsor
- University Hospital, Montpellier
Peripheral Muscle Dysfunction, COPD
Muscle Training Induced Angiogenesis in COPD
COPD patients experiment a peripheral muscle dysfunction which impact their exercise tolerance and health-related quality of life. The capillary to fiber interface is reduced and impact the exercise capacity of the patients.
- Trial name
- COPDµvasc (NCT02040363)
- Testing
- Muscular biopsy, 5-10 weeks sport training
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Undergoing Nonemergent Cardiac Surgery, Central Venous Catheter on the Superior Vena Cava (to Perform ScVO2 Measure)
SvO2 Trigger in Transfusion Strategy After Cardiac Surgery
Current international guidelines suggest a restrictive transfusion strategy, setting that Hb level at 7 g/dl is a reasonable threshold.
- Conditions
- Undergoing Nonemergent Cardiac Surgery, Central Venous Catheter on the Superior Vena Cava (to Perform ScVO2 Measure), Anemia (<9g/dL) Requiring Blood Transfusion, Hemodynamic and Respiratory Stability
- Trial name
- ReTSEACS (NCT02761564)
- Testing
- Red blood cell tranfusion, ScvO2 measure
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Healthy, Heat Exposure
Effect of Water Biking in Hot Versus Neutral Water for Heat Acclimatation
The goal of this clinical trial is to compare the efficiency of water biking training in hot (35°C) versus neutral (25°C) temperature water to elicite heat acclimation in healthy recreative athletes.
- Trial name
- THERMIDOR (NCT05727774)
- Testing
- Water Biking in hot water condition, Water Biking in neutral water condition
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Cystic Fibrosis
Small Circulating RNA as Molecular Markers of Lung Disease in Cystic Fibrosis
The aim of our study is to assess miRNAs expression profiles in the circuling blood of patients with cystic fibrosis and highlight "signatures" that could reflect the pulmonary status of patients
- Trial name
- MIRDIAMUCO (NCT02992080)
- Testing
- miRNAs isolation from blood samples of patients and control
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Low Back Pain
Assessment of the Evolution of Lumbar Spine Movement Fluidity Using Xsens Inertial Sensors in Subjects With Chronic Low Back Pain Before and After Rehabilitation
Low back pain, defined as pain located between the thoracolumbar junction and the lower gluteal fold, becomes chronic in 8% of patients.
- Trial name
- Xmouv (NCT07327554)
- Testing
- X-sens sensor
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Montpellier
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