Clinical trials: sponsored by University Hospital, Montpellier
Cardiovascular Disease
Tolerance of "on Line" Hemodiafiltration in Chronic Renal Failure Patients
The aim of this study is to appreciate the tolerance of "on line" hemodiafiltration and its impact on morbidity and cardiovascular risk factors in chronic renal failure patient.
- Trial name
- on-line-HDF (NCT01327391)
- Testing
- On line Hemodiafiltration, Hemodialysis
- Where
- France
- Volunteers
- 415 people
- Sponsor
- University Hospital, Montpellier
Air France Company's Employees Working in the Marseilles and Paris Airports (Flightline and Administrative Employees)
Nanoparticles Emitted by Aircraft Engines, Impact on the Respiratory Function:
The object of this new project is to proceed with investigations with the employees of the cohort for the first study so as to obtain a remote evolution (5 years) of their respiratory function while measuring their nanoparticle…
- Trial name
- NANOAF2 (NCT02872727)
- Testing
- Respiratoy health, biological investigations
- Where
- France
- Volunteers
- 216 people
- Sponsor
- University Hospital, Montpellier
Hip Osteoarthritis, Hip Prosthesis Infection
Image Quality of EOSedge for Radiographic Evaluation of Hip Implant
EOSedge is a precise, low dose imaging system that delivers full body, high-quality images covering the full set of musculoskeletal and orthopedic exams.
- Trial name
- PreHIPEOS (NCT05615701)
- Testing
- EOSedge imaging
- Where
- France
- Volunteers
- 97 people
- Sponsor
- University Hospital, Montpellier
Hepatitis C, Breast Cancer
Hepatitis C Screening Paired With Mammography
In France, a breast cancer screening is organized since 2004 for women aged 50-74. On the other hand, even though the seroprevalence of hepatitis C in the general French population is less than 1%, it is estimated that more than…
- Trial name
- Mammo'C (NCT05067374)
- Where
- 4 sites in France
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Bipolar Disorders, Euthymic Status
Evaluation of a Serious Game for Patients With Bipolar Disorder Involved in a Psychoeducation Group
Bipolar disorder is a condition characterized by succession of episodes- manic, hypomanic, and depressive episodes. Major risks factors of relapses are poor compliance, sleep disorder, and toxics consumption.
- Trial name
- Bipolife (NCT02936466)
- Testing
- Bipolife® group
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Montpellier
Short Sleepers, Normal Sleepers
Homeostatic Regulation of Sleep in Short Sleepers
This single-center study targets adults with distinct sleep profiles, divided into three categories: natural short sleepers, characterized by a reduced nocturnal sleep duration; subjects with idiopathic hypersomnia (IH) followed…
- Conditions
- Short Sleepers, Normal Sleepers, Idiopathic Hypersomnia Patients
- Trial name
- HOMEOSHORT (NCT07584538)
- Testing
- Actigraphy, Polysomnographie (PSG 128), TILE test
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Pulmonary Disease, Chronic Obstructive
Benefits of Epithelial Repair in COPD by Induced Pluripotent Stem Cells (iPS)
The aim of this interventional, cross-sectional and pathophysiological experimental study is to evaluate the potential of a patient's induced pluripotent stem (iPS) cells, used prior to the re-differentiation stage, to enable ex…
- Trial name
- RepCOPDiPS (NCT06755008)
- Testing
- bronchial fibroscopy
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Obesity, Insulin Resistance
Collection of Human Metabolic Tissues
This project aims at identifying new determinants of type 2 diabetes in severe obesity. To do so, a biological collection, including tissues of interest in the field of metabolism, will be collected during bariatric surgery in…
- Conditions
- Obesity, Insulin Resistance, Diabetes Mellitus, Type 2
- Trial name
- COMET (NCT02861781)
- Testing
- Collection of blood samples and tissues
- Where
- France
- Volunteers
- 270 people
- Sponsor
- University Hospital, Montpellier
Idiopathic Short Stature
Multidisciplinary Evaluation and a Genome-wide Analysis in a Cohort of Idiopathic Short Stature Patients
This trial aims to evaluate the prevalence of idiopathic short stature among children whose growth is above -2,5SD (AFPA- CRESS/Inserm -CompuGroup Medical 2018 curve) or above -2SD of the parental target size (taking child gender…
- Trial name
- PAG PETI (NCT05858606)
- Testing
- Evaluation of the prevalence of truly (authentified) idiopathic short stature after multidisciplinary clinico-radiological evaluation, analysis in a multidisciplinary consultation meeting via a secure platform (ShareConfrère) for evaluation by multidisciplinary team, Whole genome analysis for authentified idiopathic short stature
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Aneurysmal Subarachnoid Haemorrhage
Prediction of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage Using Dynamic 18F-FDG PET/CT
A pilot trial for assessing early microvascular alterations after aneurysmal subarachnoid hemorrhage using dynamic 18F-FDG PET/CT.
- Trial name
- PREDISP (NCT04356599)
- Testing
- Early dynamic 18F-FDG PET/CT assessment of cerebral glucose uptake
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Montpellier
Septic Arthritis, Inflammatory Arthritis
Differentiate Children Septic and Inflammatory Arthritis by Comparative Analysis
The purpose is to found new biomarker that differentiate septic arthritis and Juvenile Idiopathic Arthritis in children. Synovial liquid and blood samples with proteomic, MiRNA searching, multiplex cytokine analysis and cellular…
- Conditions
- Septic Arthritis, Inflammatory Arthritis, Children
- Trial name
- DIANE (NCT03827759)
- Where
- 5 sites in France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Cervical Cancer, Uterine Cervical Disease
A Proximity-incentive Strategy for Cervical Cancer Screening
In France, cervical cancer screening is based on a cervical smear for women aged 25 to 30 years and on High Risk- HPV (HR-HPV) testing for women aged 30 to 65 years.
- Conditions
- Cervical Cancer, Uterine Cervical Disease, Human Papilloma Virus
- Trial name
- RIDECA (NCT04716127)
- Testing
- Proximity-incentive strategy based on vaginal self-sampling for women 50 to 65 years who do not participate to cervical cancer screening
- Where
- 2 sites in France
- Volunteers
- 656 people
- Sponsor
- University Hospital, Montpellier
Genetic Predisposition, Breast Cancer
Pre Pectoral Implant for Immediate Breast Reconstruction Using Single Port Endoscopy in Prophylactic Indication
Implant-based reconstruction is currently the most common choice for mastectomy reconstruction. Whatever the choice of mastectomy incision, a scar remains on or near the breast volume.
- Trial name
- MRIMOP (NCT03838549)
- Testing
- Prophylactic mastectomy with immediate breast reconstruction
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Bullous Pemphigoid
Topical Steroids Alone or Associated With Methotrexate in Bullous Pemphigoid
This controlled multi-center randomized clinical trial, with direct individual benefit, will compare efficacy and safety of two strategies in non-localized BP care: a combined regimen using initial superpotent topical steroids…
- Trial name
- BP/MTX (NCT02313870)
- Testing
- clobetasol propionate + Methotrexate, clobetasol propionate alone
- Where
- France
- Volunteers
- 322 people
- Sponsor
- University Hospital, Montpellier
Heart Failure
Factors Influencing Participation in PRADO and Telemedicine Interventions in Heart Failure
Patients with heart failure (HF), after hospitalization, present a marked fragility. Interventions improving the coordination of care actors at the time of discharge from hospitalization have been tested and have shown, in…
- Trial name
- PARTI-PARC (NCT05417490)
- Testing
- PRADO-IC, Remote monitoring
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University Hospital, Montpellier
Knee Osteoarthritis
Evaluation of Mobility in Subjects With Severe Knee Osteoarthritis Who Are to Undergo Total Knee Replacement
Osteoarthritis (OA) is the most common joint disease. It is characterized by a progressive destruction of all the components of the joint, especially the cartilage.
- Trial name
- MOUV-GOPRO (NCT05488093)
- Testing
- X-sens sensor
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Cerebrovascular Accident
Measuring the Concurrent Validity of the Upper Limb Use Ratio With Accelerometers in an Ecological Situation After Stroke.
The purpose of this stufy is to measure the concurrent validity of the upper limb use ratio with accelerometers in an ecological situation after stroke.
- Trial name
- ValidFUR (NCT06509542)
- Testing
- Objective assessment of upper limb use during activities in ecological situation
- Where
- 2 sites in France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Montpellier
Chronic Kidney Diseases
Proteinuria in Renal Transplant Patients Treated With Dapagliflozin
The prevalence of chronic kidney disease is rising steadily and represents a major public health challenge. Hypertension and proteinuria are two factors strongly associated with the progression of chronic kidney disease (CKD) and…
- Trial name
- DAPAGREFFE (NCT06165601)
- Testing
- Follow-up at D14, Follow-up at M1
- Where
- France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Montpellier
Cerebral Palsy, Scoliosis
Effects of Neuromuscular Scoliosis Surgery on Nutritional Metabolism
Cerebral palsy is the primary cause of disability in France. It is a non-progressive condition leading to movement and posture troubles, but also to cognitive and sensory problems.
- Trial name
- SORONOUS (NCT07255495)
- Testing
- Absorptiometry and indirect calorimetry, Questionnaires
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Montpellier
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Phenotyping of Type 2 Inflammation Profile by Rheology of Nasal Secretions and Tissue Quantification of Eosinophilic Polymorphonuclear Cells in the Middle Turbinate
This monocentric, interventional study (category RIPH2) aims to characterize the rheological properties of sinonasal secretions in patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP).
- Trial name
- PheRhEos (NCT07524127)
- Testing
- Sinonasal sample collection and inflammatory assessment
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
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