Clinical trials: sponsored by University Hospital Heidelberg
Coronary Artery Disease
hsTnT After Elective Coronary Angiography
A prospective Study, aiming to understand and analyse the key role of the novel High Sensitivity Troponin T (hsTnT) within a group of patients undergoing an uncomplicated coronary angiography without receiving any additional…
- Trial name
- NCT01735500
- Where
- Germany
- Volunteers
- 545 people
- Sponsor
- University Hospital Heidelberg
Chronic Ankle Instability
Neuromuscular Control of the Ankle With External Support
Untreated ankle sprains often remain symptomatic and may end in chronic instability. The aim of our study is to quantify the stabilizing effect of different devices.
- Trial name
- NCT01781351
- Testing
- Taping the ankle
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Coronary Artery Disease, Myocardial Infarction
Mi-RNAs and Specificity of Hs-TnT in Symptomatic ED Patients
Biomarkers play a key role in the diagnostic workup of patients presenting to an emergency department (ED). European and American guidelines recommend cardiac Troponin (T or I) as the biomarker gold standard for the diagnosis of…
- Trial name
- NCT02116153
- Sponsor
- University Hospital Heidelberg
Stroke
Prehospital COOLing 1 (PreCOOL 1)
Elevated body temperature was shown to be associated with worse outcome in acute stroke patients. PreCOOL 1 aims to investigate efficacy, feasibility and safety of prehospital cooling with cold infusions in stroke patients.
- Trial name
- PreCOOL (NCT01669408)
- Testing
- Cold crystalloid infusions, 0.9%NaCl or Ringer's solution
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital Heidelberg
Ischemic Stroke, Hemorrhagic Stroke
A Randomized Trial Comparing 2 Methods for Rapid Induction of Cooling in Stroke Patients, Cold Infusions vs. EMCOOLS Flex.Pads (iCOOL 2)
Mild hypothermia improves outcome in patients with global cerebral ischemia after cardiac arrest. Hypothermia seems promising also in other acute hypoxic-ischemic or in brain swelling associated cerebrovascular disease.
- Trial name
- iCOOL 2 (NCT01584167)
- Testing
- Cold crystalloid infusions, 0.9%NaCl or Ringer's solution, EMCOOLS Flex.Pads
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Heidelberg
Pediatric Overweight
Overweight Children - Musculoskeletal Consequences
The purpose was to investigate the consequences of pediatric overweight on the musculoskeletal system, postural control and proprioception, and to analyze prospectively the influence of ball games and nutrition counseling.
- Trial name
- NCT01825174
- Testing
- Ball games program, Nutrition counseling
- Where
- Germany
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Chronic Ankle Instability
External Ankle Supports - 3D Motion Analysis
Untreated ankle sprains often remain symptomatic and may end in chronic instability. The aim of our study is to quantify the stabilizing effect of different devices.
- Trial name
- NCT01810471
- Testing
- Applying ankle support device (white non-elastic tape, kinesiotape (TM), soft brace (Malleotrain TM)
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Hallux Rigidus
Motion Analysis in Patients With Hallux Rigidus
The aim was to investigate with a multi-segmental foot model the kinetic and kinematic in patients with a hallux rigidus, before and after different type of surgery.
- Trial name
- NCT01804491
- Testing
- Motion Analysis
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Postural Control
Dynamic Postural Control After Exercise
The aim was to analyze the influence of fatigue on the dynamic postural control in one-leg standing and in jump landing, followed by stabilization or side jumps, and to compare athletes of different levels with control subjects.
- Trial name
- NCT01799434
- Testing
- treadmill run
- Where
- Germany
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Biochemical and Genetic Markers in Liver Diseases
Biochemical and Genetic Markers in Liver Diseases
Investigation of biochemical and genetic markers in liver disease that might have an influence on the course of the disease
- Trial name
- NCT01706614
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- University Hospital Heidelberg
Ischemic Stroke, Hemorrhagic Stroke
A Randomized Trial Comparing 2 Methods for Rapid Induction of Cooling in Stroke Patients, Cold Infusions vs. EMCOOLS Brain.Pad (iCOOL 3)
Mild hypothermia improves outcome in patients with global cerebral ischemia after cardiac arrest. Hypothermia seems promising also in other acute hypoxic-ischemic or in brain swelling associated cerebrovascular disease.
- Trial name
- iCOOL 3 (NCT01584180)
- Testing
- Cold crystalloid infusions, 0.9%NaCl or Ringer's, EMCOOLS Brain.Pad
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Heidelberg
Ischemic Stroke, Hemorrhagic Stroke
A Randomized Trial Comparing 2 Methods for Rapid Induction of Cooling in Stroke Patients, Cold Infusions vs. RhinoChill (iCOOL 1)
Mild hypothermia improves outcome in patients with global cerebral ischemia after cardiac arrest. Hypothermia seems promising also in other acute hypoxic-ischemic or in brain swelling associated cerebrovascular disease.
- Trial name
- iCOOL 1 (NCT01573117)
- Testing
- RhinoChill, Cold crystalloid infusions, 0.9%NaCl or Ringer's solution
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Heidelberg
Coronary Artery Disease
Dobutamine Stress Cardiac Magnetic Resonance Versus Echocardiography for the Assessment of Outcome. Are the Two Imaging Modalities Comparable?
Dobutamine stress echocardiography (DSE) and cardiac magnetic resonance (DCMR) are both established non-invasive techniques, used in the clinical routine for the diagnostic classification and risk stratification of patients with…
- Trial name
- NCT01568502
- Where
- Germany
- Volunteers
- 5,008 people
- Sponsor
- University Hospital Heidelberg
Obstipation
Coffee Against Obstipation in Intensive Care Treatment
Coffee might stimulate bowel movement and thus overcome obstipation in intensive care unit (ICU) patients.
- Trial name
- NCT01473966
- Testing
- coffee, coffee rectally
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University Hospital Heidelberg
Pancreatic Neoplasms
Trial of Neoadjuvant Short Course IMRT Followed by Surgery and IORT for Resectable Pancreatic Cancer
The current standard treatment for patients with primarily resectable pancreatic tumors consists of surgery followed by adjuvant chemotherapy.
- Trial name
- NEOPANC (NCT01372735)
- Testing
- neoadjuvant short course IMRT, IORT
- Where
- 3 sites in Germany
- Volunteers
- 46 people
- Sponsor
- University Hospital Heidelberg
Crohn's Disease
Green Tea in Crohn's Disease
The purpose of this study is to assess whether green tea or coffee influence the course and life quality of patients with mild to moderately active Crohn's disease.
- Trial name
- NCT01231217
- Testing
- Green tea (Camellia sinensis), Coffee
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Heidelberg
Ovarian Cancer, Tubal Carcinoma
Consolidation Whole Abdominal Intensity-Modulated Radiation Therapy (IMRT) in Advanced Ovarian Cancer
The primary objective of this phase-II study is to assess the toxicity of consolidation intensity-modulated whole-abdominal radiotherapy using tomotherapy in patients with advanced optimally debulked stage International…
- Conditions
- Ovarian Cancer, Tubal Carcinoma, Primary Peritoneal Carcinoma
- Trial name
- OVAR-IMRT-02 (NCT01180504)
- Testing
- intensity-modulated whole-abdominal radiotherapy
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- University Hospital Heidelberg