Clinical trials: sponsored by University of Aarhus
Idiopathic Pulmonary Fibrosis (IPF)
D Vitamin and Alveolar Macrophages in Idiopathic Pulmonal Fibrosis
The goal of this observational study is to gain deeper insights into human macrophages and vitamin D, and their interplay, within Idiopathic Pulmonary Fibrosis (IPF).
- Trial name
- NCT06909409
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
The Focus is to Investigate Effect of an Educational Video on Fecundity Knowledge Among Young Adults
Young Adults' Fecundity Knowledge and Fertility Intentions and Reproductive Behavior
This RCT investigates the impact of an educational video on fecundity knowledge among young adults. The video discusses several risk factors associated with fecundity, such as age and smoking.
- Trial name
- NCT06631950
- Testing
- Educational intervention
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Brain Concussion, Mild Traumatic Brain Injury
Get Going After concussIonN Lite
Background: Concussion affects around 25 000 people each year in Denmark. A large research initiative (GAIN 2.0) has been established, and the current study is a part of this initiative. Aims: 1.
- Conditions
- Brain Concussion, Mild Traumatic Brain Injury, Commotio Cerebri
- Trial name
- GAIN Lite (NCT05233475)
- Testing
- Enhanced usual care (EUC), Get Going after concussIoN Lite
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Cervical Cancer, Sentinel Lymph Node
HPV in Sentinel Lymph Nodes of Cervical Cancer Patients
This study examines sentinel lymph node tissue from early stage cervical cancer patients treated with radical surgery and removal of pelvic sentinel lymph nodes (SLN).
- Conditions
- Cervical Cancer, Sentinel Lymph Node, HPV-Related Cervical Carcinoma
- Trial name
- NCT03749707
- Testing
- HPV analysis
- Where
- Denmark
- Volunteers
- 127 people
- Sponsor
- University of Aarhus
HPV-Related Carcinoma, HPV-Related Malignancy
HPV in Blood Samples From Cervical Cancer Patients.
By means of digital droplet PCR (ddPCR) anf targeted Next Generation Sequencing (NGS), this study examines blood samples from patients newly diagnosed with cervical cancer to investigate whether it is possible to measure the…
- Trial name
- NCT03749720
- Testing
- Blood sample
- Where
- 2 sites in Denmark
- Volunteers
- 141 people
- Sponsor
- University of Aarhus
Non-Alcoholic Fatty Liver Disease, Metabolic Syndrome
Dairy Protien Rich Diet for NAFLD Patients
The overarching aim of this project is to investigate effects of dietary interventions on nonalcoholic fatty liver disease (NAFLD) severity and to delineate the relationship with improvements in metabolic aberrations in liver…
- Conditions
- Non-Alcoholic Fatty Liver Disease, Metabolic Syndrome, Caseins, Whey
- Trial name
- DAIPRO-NAFLD (NCT04841915)
- Testing
- High-Protein Diet, Clinical dietician, Weight loss
- Where
- 2 sites in Denmark
- Volunteers
- 46 people
- Sponsor
- University of Aarhus
Healthy, Cytotoxicity
Cytotoxicity of Yellow Fever Specific CD8 T Cells Following YF-17D Vaccination
Investigating cytotoxicity of yellow fever specific CD8 T cells following YF-17D vaccination and the following licensing of these epitope-specific CD8 T cells
- Conditions
- Healthy, Cytotoxicity, Yellow Fever Vaccination Reaction
- Trial name
- CYF-8 (NCT04083430)
- Testing
- Yellow Fever Vaccine
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Anxiety Depression
Cancer Caregiver Burden: Targeting Emotion Regulation in a Trial
Informal caregivers of cancer patients report high levels of psychological distress as evidenced in markedly increased levels of anxiety and depression.
- Trial name
- ERT-ICs (NCT02322905)
- Testing
- Emotion Regulation Therapy
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Depression
Behavioral Activation for Depression: A Randomized Controlled Trial
The present study is a randomized controlled trial that will evaluate two versions of behavioral activation (BA); one version which is a standard BA program and one which is a motor enhanced BA program (mBA).
- Trial name
- NCT04700774
- Testing
- Behavioral activation
- Where
- Denmark
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Multiple Sclerosis
Effects of MS Ballroom Fitness on Balance, Walking Capacity, and Well-being in Multiple Sclerosis
The goal of the present study is to evaluate the effects of a dance-based concept entitled MS Ballroom Fitness (developed in Denmark by PT Elisabeth Dalsgaard) in persons with multiple sclerosis (pwMS).
- Trial name
- NCT06028776
- Testing
- MS Ballroom Fitness
- Where
- Denmark
- Volunteers
- 95 people
- Sponsor
- University of Aarhus
Melanoma
Perioperative Treatment With Tranexamic Acid in Melanoma
Surgery is a key element in the treatment of melanoma, and naturally linked with an inflammatory response and recruitment of innate immune cells.
- Trial name
- PRIME (NCT05899465)
- Testing
- Tranexamic acid, Saline
- Where
- 5 sites in Denmark
- Volunteers
- 1,204 people
- Sponsor
- University of Aarhus
Cerclage, Cervical, Cervical Insufficiency
Long-Term Patient-Reported Maternal Outcomes Following Abdominal Cerclage for the Prevention of Preterm Birth
This study aims to explore the maternal patient reported outcomes on pelvic pain sexual health anxiety and depression bladder discomfort foreign body sensation trust in the cerclage, and how these parameters affect the general…
- Trial name
- NCT06875401
- Testing
- Abdominal cerclage (open or laparoscopic)
- Where
- Denmark
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Postprandial Lipid Metabolism
Effects of Intact and Disrupted Milk Fat Globule Membrane on Postprandial Metabolic Response to High-fat Dairy in Healthy Individuals
The aim of the study is to investigate the effects of milk fat globule membrane (MFGM) content and intactness on postprandial metabolic response to a high-fat meal in humans.
- Trial name
- NCT06340412
- Testing
- Sandwich with butter-like dairy product (40g milk fat) with intact MFGM. One sandwich for breakfast and one sandwich for lunch., Sandwich with butter-like dairy product (40g milk fat) with disrupted MFGM. One sandwich for breakfast and one sandwich for lunch., Sandwich with butter-like dairy product (40g milk fat) without MFGM. One sandwich for breakfast and one sandwich for lunch.
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Sarcoidosis, Osteoporosis Risk
Bone Mineral Density in Patients With Sarcoidosis
To assess the frequency and risk factors of decreased bone mineral density (BMD) and vertebral fractures in Danish patients with sarcoidosis.
- Trial name
- NCT06238037
- Where
- Denmark
- Volunteers
- 144 people
- Sponsor
- University of Aarhus
Diabetes Mellitus, Obesity
Investigating Muscle Failure in Diabetic Myopathy
The goal of this observational study is to assess if diabetes and obesity are independently related to functional and structural muscle deficits, and how muscular deficits relate to metabolic properties of diabetes and obesity.
- Conditions
- Diabetes Mellitus, Obesity, Chronic Hyperglycaemia, Weight Loss
- Trial name
- NCT05685927
- Testing
- 6-months of medically assisted glycemic improvement, Bariatric surgery
- Where
- Denmark
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Cystic Fibrosis (CF), CFTR Gene Mutation
Cystic Fibrosis in the Kidney: Monitoring the Effectiveness of Elexacaftor/tezacaftor/ivacaftor in Urine After a Short Pause of Therapy
In cystic fibrosis (CF) renal base excretion is impaired, due to mutations in the Cystic Fibrosis Transmembrane Regulator (CFTR) gene, since CFTR function is crucial in regulation of the kidney's HCO3- excretion.
- Trial name
- NCT05818319
- Testing
- 12 hours ETI pause, 36 hours ETI pause, 60 hours ETI pause
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- University of Aarhus
Inflammation, Obesity and Type 2 Diabetes
Inflammation's Impact on Heart Disease and Diabetes
The goal of this observational study is to evaluate the inflammatory response associated with cardiometabolic diseases, and whether these can be reduced by ex vivo treatment with therapeutic agents.
- Conditions
- Inflammation, Obesity and Type 2 Diabetes, Obesity, Metabolic Syndrome
- Trial name
- INFO (NCT06752018)
- Testing
- Gastric bypass
- Where
- Denmark
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Postoperative Ileus, Bowel Paralysis
Gastrointestinal Stimulation As a Treatment of Postoperative Ileus Following Extensive Surgery
The goal of this clinical trial is to investigate the effect of gastrointestinal stimulation with a pacemaker on the length of postoperative bowel paralysis in patients undergoing major abdominal surgery due to metastasizing…
- Trial name
- STIMULATE (NCT05752071)
- Testing
- Gastric electrical stimulation
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Fertility, Fecundability
Physical Activity, Fertility, and Spontaneous Abortion in Danish Couples Trying to Conceive
Physical activity in both the preconception period and during pregnancy may enhance the probability of getting pregnant and reduce the risks of complications during pregnancy.
- Conditions
- Fertility, Fecundability, Time-to-Pregnancy, Spontaneous Abortion
- Trial name
- SF/Activity (NCT06705712)
- Testing
- Use of activity trackers and motivational conversations to enhance focus on physical activity among women trying to conceive.
- Where
- Denmark
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Preterm Birth, Hyperglycemia
Blood Glucose in Pregnant Non-diabetic Women During Treatment With Betamethasone for Fetal Lung Maturation
In case of threatening preterm birth, it is standard to recommend treatment with betamethasone to accelerate fetal lung maturation.
- Conditions
- Preterm Birth, Hyperglycemia, Neonatal Hypoglycemia, Threatened Preterm Labor
- Trial name
- NCT06794307
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- University of Aarhus
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