Clinical trials: sponsored by University of Aarhus
Genetic Predisposition
Simultaneous tDCS and Computerised Gamified Short-term Memory Task Feasibility
The goal of this observational study is to gain insight into the effects of transcranial direct current stimulation (tDCS) on short-term memory task performance and the feasibility of tDCS in overtly healthy carriers of the…
- Trial name
- ACTTDCS-FG (NCT06402266)
- Testing
- tDCS
- Where
- Denmark
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Radiculopathy Lumbar, Radiculopathy Sacral
Precision Treatment of Lumbar Spine Surgery Through Advanced Nerve Root Blockade
The overall purpose of the study is to investigate whether selective spinal nerve root blocks can improve diagnostics of radiculopathy due to lumbar disc herniation (LDH), foraminal stenosis (FS), and recess stenosis (RS), and…
- Conditions
- Radiculopathy Lumbar, Radiculopathy Sacral, Herniated Disc, Foraminal Stenosis
- Trial name
- PLAN (NCT06143813)
- Testing
- Selective nerve root block (SNRB)
- Where
- Denmark
- Volunteers
- 180 people
- Sponsor
- University of Aarhus
Chronic Thromboembolic Pulmonary Hypertension
BPA vs. PEA in CTEPH
Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare and potentially life-threatening progressive disease that evolves from unresolved pulmonary embolism.
- Trial name
- GO-CTEPH (NCT05110066)
- Testing
- Pulmonary endarterectomy, Balloon pulmonary angioplasty
- Where
- 2 sites in Denmark, United Kingdom
- Volunteers
- 139 people
- Sponsor
- University of Aarhus
Healthy
The GALAXY-1 Project
"The understanding of the two sugars, glucose and fructose, has been thoroughly investigated regarding their impact on human metabolism during exercise.
- Trial name
- NCT05986500
- Testing
- Galactose, No intervention
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Obstructive Sleep Apnea, Tonsillar Hypertrophy
Tonsillectomy vs. Tonsillotomy in Adults With Obstructive Sleep Apnea
The primary purpose of this randomized controlled trial s to investigate whether surgical reduction of palatine tonsils (tonsillotomy) is a superior treatment compared to complete surgical removal of palatine tonsils…
- Trial name
- NCT06376383
- Testing
- Tonsillectomy, Tonsillotomy
- Volunteers
- 464 people
- Sponsor
- University of Aarhus
Hip Arthritis
A Migration and Bone Density Study Comparing Hi-Fatigue Bone Cement and Palacos Bone Cement
The purpose of this scientific study is to compare early migration of hip prostheses in respect to the bone in order to determine whether there is a clinical difference between the two investigated bone cements (which one is best…
- Trial name
- NCT01289834
- Testing
- Hi-Fatigue Bone Cement, Palacos Bone Cement
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- University of Aarhus
Post Concussive Symptoms
Chasing Biomarkers in Post-concussion Syndrome
The goal of this study was to investigate the biomarkers, neurofilament light chain, inflammatory markers, calcitonin-gene-related peptide, and metabolites from the kynurenine pathway in patients with severe post-concussive…
- Trial name
- NCT05812742
- Testing
- Early intervention programme, Enhanced usual care
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Analgesia
The Effects of Pain and Pain Relief on Peripheral Nerve Excitability
This study will assess changes in nerve excitability of C-fibers, and changes in sympathetic or parasympathetic tone, when the subject experiences pain and pain relief.
- Trial name
- NCT06356376
- Testing
- Heat Stimulation
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Endometriosis
MY-ENDO -- Mind Your ENDOmetriosis: a Digital Mindfulness- and Acceptance-based Endometriosis Self-management Program
The purpose of the study is to assess the effect of a digital mindfulness- and acceptance-based psychological intervention on quality of life, work ability, pain experience and physical and mental health in participants…
- Trial name
- NCT06211231
- Testing
- Digitally delivered mindfulness- and acceptance-based psychological intervention
- Where
- 2 sites in Denmark
- Volunteers
- 255 people
- Sponsor
- University of Aarhus
Anastomotic Leak Rectum, Rectal Cancer
Healing of Rectal Anastomosis Sealed With a Concentrate Derived From the Patient's Blood, After Rectal Cancer Surgery
Rectal cancer is one of the most frequent cancer diseases, with more than 1500 new cases per year in Denmark. Fortunately, if the tumor is discovered early, surgeons can remove the part of the intestine that is afflicted, and…
- Conditions
- Anastomotic Leak Rectum, Rectal Cancer, Anastomotic Leakage
- Trial name
- OBANORES (NCT05293054)
- Testing
- Application of autologous fibrin matrix (Obsidian)
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Mental Health, Youth
On Top of Everything
Our primary aim of this trial is to evaluate the effectiveness of a teacher training programme to teach mindfulness as part of regular classroom teaching in the total population of students in Danish upper secondary schools and…
- Conditions
- Mental Health, Youth, Mindfulness, Stress
- Trial name
- NCT04610333
- Testing
- Modified MBSR programme
- Where
- Denmark
- Volunteers
- 992 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Mental Health, Children
Stress-free Everyday LiFe for Children and Adolescents REsearch
The primary aim is to evaluate the effectiveness of a profound school teacher training programme to teach a mindfulness-based programme (.b) in Danish schools on the pupils self-reported mental well-being at seven months.
- Conditions
- Mental Health, Children, Adolescent, Mindfulness
- Trial name
- SELFCARE (NCT04208113)
- Testing
- School teacher training /.b
- Where
- Denmark
- Volunteers
- 1,774 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Stress Reduction, Mental Well-being
Effectiveness of MBSR Among Student Teachers
The aim is to evaluate the effectiveness of Mindfulness-based Stress Reduction among Danish student teachers on their mental well-being. The study is a randomised, controlled trial including 100 teachers.
- Trial name
- NCT04558099
- Testing
- MBSR
- Where
- Denmark
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Turner Syndrome, Cardiovascular Diseases
Lymphedema, Low-grade Inflammation and the Vasculature in Turner Syndrome
100 women with karyotype verified TS, previously examined at 4 study visits during a 19-year period will be asked to participate in a 5th study visit. Healthy age-matched females will be included as controls in a ratio 2:1.
- Conditions
- Turner Syndrome, Cardiovascular Diseases, Lymphedema, Inflammation
- Trial name
- TSCOR_V (NCT06325618)
- Testing
- No intervention other than obtaining biopsies, Indocyanine green (ICG)
- Where
- Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
NAFLD, Type 2 Diabetes
Postprandial VLDL-triglyceride Metabolism in Type 2 Diabetes Patients With and Without NAFLD
Non-alcoholic fatty liver disease (NAFLD) covers a spectrum from simple reversible hepatic steatosis to inflammation and fibrosis termed steatohepatitis (NASH).
- Trial name
- NCT05044130
- Testing
- High-fat mixed-meal tolerance test (HF-MMTT)
- Where
- Denmark
- Volunteers
- 17 people
- Sponsor
- University of Aarhus
Rotator Cuff Tear, Proximal Humeral Fracture
The Accuracy of Ultrasound in Detecting Rotator Cuff Tears in Proximal Humerus Fracture Patients
The aim of this study is to determine the diagnostic accuracy of ultrasonography (US) in detecting full-thickness (a lesion that extends through both the bursal and articular part of the tendon) rotator cuff tear in patients who…
- Trial name
- NCT03567954
- Testing
- Ultrasound examination of the rotator cuff tendons
- Where
- 2 sites in Denmark, Finland
- Volunteers
- 25 people
- Sponsor
- University of Aarhus
Head and Neck Neoplasms
Feasibility Testing a Decision-support Intervention for Clinical Trials
A decision-support intervention are developed for a Danish nationwide randomised controlled trial (RCT) among patients with laryngeal and pharyngeal cancer referred to curative intended radiotherapy.
- Trial name
- NCT06291610
- Testing
- Clinical trial decision support intervention
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Pain, Acute, Pain, Postoperative
Intraoperative Methadone in Children Undergoing Surgery
A prospective double-blind, randomized controlled trial investigating the effect of a single-dose of intraoperative methadone on postoperative pain and opioid consumption in 96 children undergoing open urological surgery.
- Conditions
- Pain, Acute, Pain, Postoperative, Children, Only
- Trial name
- METACEBO (NCT04680286)
- Testing
- Methadone Hydrochloride
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Migraine
Cabergoline as a Preventive Treatment for Chronic Migraine
Headache disorders constitute a major global disease burden, and migraine - with a one-year prevalence of 15 % - is the sixth most disabling condition. Though a common disease, the pathogenesis is still unclear.
- Trial name
- NCT05525611
- Testing
- Cabergoline 0.5 MG
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- University of Aarhus
Sarcoidosis
ACE and HLA Genotypes Predict Severity and Disease Progression in Danish Sarcoid Patients
Sarcoidosis is a multisystem granulomatous disease of unknown cause histologically characterized by noncaseating granulomas. Genetic factors affect disease course, which is highly variable and difficult to predict.
- Trial name
- NCT04462068
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Aarhus