Clinical trials: sponsored by University of Aarhus
Orthodontic Appliances, Fixed
Computer-aided Indirect Bonding Versus Traditional Direct Bonding of Brackets in Orthodontic Patients
Accurate bracket positioning is one of the keys for effective orthodontic treatment. Traditionally, orthodontic brackets are positioned one-by-one on the teeth of the patient, with the so-called direct bonding method.
- Trial name
- NCT04395625
- Testing
- Direct bonding of Orthodontic brackets, Indirect bonding of Orthodontic brackets
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Multiple Sclerosis
Early Exercise Efforts in Multiple Sclerosis
This study seeks to investigate whether early exercise efforts can expand the use of exercise in Multiple sclerosis (MS), from symptom treatment only, to early supplementary disease-modifying treatment.
- Trial name
- NCT03322761
- Testing
- Systematic exercise training, Educational program
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- University of Aarhus
Postoperative Pain
Clinical Effectiveness and Safety of Intraoperative Methadone in Patients Undergoing Laparoscopic Hysterectomy
The role of a single-dose of intraoperative methadone on postoperative pain and opioid consumption in patients undergoing hysterectomy remains scarcely explored.
- Trial name
- NCT03908060
- Testing
- Methadone, Morphine
- Where
- Denmark
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Dyspnea
Point-of-care Ultrasound in Prehospital Dyspnea
Point-of-care ultrasound in patients with dyspnoea has been shown to alter patient treatment and the time to correct treatment when performed in emergency departments.
- Trial name
- NCT03905460
- Testing
- Point-of-care ultrasound
- Where
- Denmark
- Volunteers
- 219 people
- Sponsor
- University of Aarhus
Ketogenic Dieting
The Effects of Ketogenic Diet on the Heart and Brain
A ketogenic diet consists of a high intake of fats and a limited intake of carbohydrates, which causes an increased level of ketone bodies in the body.
- Trial name
- NCT05012748
- Testing
- Ketogenic diet
- Where
- Denmark
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Fetal Growth Retardation
Day to Day Variation in Fetal Heart Rate Variability
This study evaluates the day-to-day variation in fetal heart rate variability based on non-invasive fetal-ECG (NI-FECG). Furthermore, the effect of fetal movements on fetal heart rate variability will be assessed.
- Trial name
- (FHRV) (NCT04289350)
- Testing
- fetal heart rate variability
- Where
- Denmark
- Volunteers
- 44 people
- Sponsor
- University of Aarhus
Pain, Chronic, Breast Cancer
Optimizing Psychological Treatment for Pain After Breast Cancer
The present study aims to optimize psychological treatment for pain after breast cancer by identifying active treatment components.
- Trial name
- NCT05444101
- Testing
- Mindful attention, Decentering, Values and committed action
- Where
- Denmark
- Volunteers
- 185 people
- Sponsor
- University of Aarhus
Breastfeeding, Diabetes Mellitus
Artificial Sweeteners in Breast Milk
This study will investigate how some artificial sweeteners (AS) cross from blood to breastmilk in breastfeeding women after oral intake.
- Conditions
- Breastfeeding, Diabetes Mellitus, Overweight
- Trial name
- NCT04578431
- Testing
- Artificial sweeteners (acesulfame-potassium, sucralose, saccharine, cyclamate)
- Where
- Denmark
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Wilsons Disease
sCD163 and sMR in Wilsons Disease - Associations With Disease Severity and Fibrosis
The aim is to investigate macrophage activation markers and correlations to liver fibrosis in patients with Wilsons Disease. Researchers wish to investigate associations to neurologic and metabolic liver function.
- Trial name
- NCT02702765
- Testing
- Fibroscan, Ultrasound, Galactose
- Where
- Denmark
- Volunteers
- 33 people
- Sponsor
- University of Aarhus
Bodily Distress Disorder Moderate, Fibromyalgia
Feasibility and Acceptability of the Internet-delivered Treatment "One Step at the Time" for Bodily Distress Syndrome
This uncontrolled feasibility pilot study explores the acceptability and potential effect of a 14 week, 11-module, therapist-assisted, internet-delivered treatment program, "One step at the time", for patients moderately affected…
- Conditions
- Bodily Distress Disorder Moderate, Fibromyalgia, Chronic Fatigue Syndrome, Irritable Bowel Syndrome
- Trial name
- NCT04870476
- Testing
- Internet-delivered treatment: "One step at the time"
- Sponsor
- University of Aarhus
Hypoglycemia, Diabetes Mellitus, Type 1
Comparison Between Hypoglycemic Counter Regulatory Responses in Type 1 Diabetics vs Control Subjects
This study compares the hypoglycemic counter regulatory response in type 1 diabetics and in healthy control subjects with and without antecedent hypoglycemia
- Trial name
- NCT03034226
- Testing
- Glucose clamp technique
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Graves' Disease
D-vitamin And Graves' Disease; Morbidity And Relapse Reduction
The purpose of this study is to investigate the effects of vitamin D supplementation on morbidity and risk of relapse in patients with Graves' disease.
- Trial name
- DAGMAR (NCT02384668)
- Testing
- Cholecalciferol
- Where
- 8 sites in Denmark
- Volunteers
- 278 people
- Sponsor
- University of Aarhus
Chronic Low-back Pain, Facet Joint Pain
Cryoneurolysis Outcome on Pain Experience (COPE) in Patients With Low-back Pain
This study will provide information on the effectiveness of cryoneurolysis for patients with facet joint pain syndrome, and help to establish whether cryoneurolysis should be implemented in clinical practice for this patient…
- Conditions
- Chronic Low-back Pain, Facet Joint Pain, Degeneration Lumbar Spine, Facet Joint Syndrome
- Trial name
- COPE (NCT04786145)
- Testing
- Cryoneurolysis, Radiofrequency ablation
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Heart Failure, Ketosis
Modulation of Circulating Levels of the Ketone Body 3-hydroxybutyrate in Patients With Chronic Heart Failure: Cardiovascular Effects
The ketone body 3-hydroxybutyrate (3-OHB) is a naturally occurring energy substrate, and is associated with increased life span and improved health.
- Conditions
- Heart Failure, Ketosis, Ketonemia
- Trial name
- KETO-KINETICS1 (NCT04443426)
- Testing
- Oral 3-hydroxybutyrate salts, Ketone Monoester
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- University of Aarhus
Primary Biliary Cirrhosis, Liver Inflammation
sCD163 in PBC Patients - Assessment of Treatment Response
Primary biliary cholangitis (PBC) is an autoimmune chronic liver disease, characterised by destruction of the small intrahepatic bile ducts. Ursodeoxycholic acid (UDCA) is the first line treatment for patients with PBC.
- Conditions
- Primary Biliary Cirrhosis, Liver Inflammation, Ursodeoxycholic Acid
- Trial name
- NCT02931513
- Testing
- Blood samples, Fibroscan, Questionnaires
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Primary Biliary Cirrhosis
Bezafibrate in Patients With Primary Biliary Cholangitis (PBC)
Up to 40% of patients with PBC have an inadequate response to standard treatment with UDCA, hence bezafibrate, a PPAR-agonist is being introduced as add-on therapy in these patients.
- Trial name
- NCT04514965
- Testing
- Blood sampling, Fibroscan, Question
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Primary Biliary Cirrhosis, Liver Inflammation
sCD163 in PBC Patients - Assessment of Disease Severity and Prognosis
Primary biliary cholangitis (PBC) is an autoimmune chronic liver disease, characterised by destruction of the small intrahepatic bile ducts.
- Trial name
- NCT02924701
- Testing
- Blood samples, fibroscan and questionaires
- Where
- Denmark
- Volunteers
- 168 people
- Sponsor
- University of Aarhus
Unipolar Depression
Efficacy of Daylight as Adjunctive Treatment in Patients With Depression
The aim of this study is to improve the treatment effect for outpatients with depression by adding regular daily morning daylight exposure to their treatment with antidepressants.
- Trial name
- NCT04712968
- Testing
- Regular exposure to morning daylight
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Radius Distal Fracture, Distal Radius Fracture
Operative vs. Conservative Treatment of Distal Radius Fractures
Even though broken wrists are of frequent occurrence, the investigators see a lack of extensive and well executed international studies to clarify which is the best treatment for elderly participants at 65+ years.
- Conditions
- Radius Distal Fracture, Distal Radius Fracture, Radius Fracture Distal
- Trial name
- NCT03716661
- Testing
- ORIF
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Aarhus
Fecal Incontinence, Constipation - Functional
Examination of a New Irrigation System for Transanal Irrigation in Children With Fecal Incontinence
The aim of this study is to investigate if a new irrigation system for transanal irrigation (TAI) is effective and more tolerable than the currently used system at the Pediatric Ward at Aarhus University Hospital.
- Trial name
- NCT05032534
- Testing
- Cone Small, Qufora A/S, Colotip, Coloplast A/S
- Where
- 2 sites in Denmark
- Volunteers
- 14 people
- Sponsor
- University of Aarhus
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