Clinical trials: sponsored by University of Aarhus
Central Nervous System Lymphoma
Nordic Study in Newly Diagnosed Primary Central Nervous System (CNS) Lymphoma
The purpose of the study is to test the efficacy and tolerability of a multiagent chemotherapy treatment regimen without radiotherapy in patients with newly diagnosed lymphoma in the brain.
- Trial name
- NCT01458730
- Testing
- Immunochemotherapy
- Where
- Denmark
- Volunteers
- 66 people
- Sponsor
- University of Aarhus
Malignant Lymphoma
Phase 1/2 Study of the Combination of Pixantrone, Etoposide, Bendamustine and, in CD20 Positive Tumors, Rituximab in Patients With Relapsed Aggressive Non-Hodgkin Lymphomas of B- or T-cell Phenotype - the P[R]EBEN Study
This is a phase 1/2 open label study to assess the safety and efficacy of pixantrone in combination with bendamustine, etoposide and , for CD20 positive B-cell lymphomas, rituximab (P[R]EBEN), in patients with relapsed aNHL of B…
- Trial name
- NCT02678299
- Testing
- PREBEN
- Where
- 18 sites in Denmark, Finland and 3 more
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Heart Failure, Ketosis
Weight-Adjusted Dosing of 3-OHB in Patients With Chronic Heart Failure
We aim to investigate the hemodynamic effects of weight-adjusted dosing of ketone monoester en patients with chronic heart failure.
- Trial name
- KINETICS2 (NCT04594265)
- Testing
- KetoneAid KE4 Pro Monoester, Science in Sport Go Enegy
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- University of Aarhus
Acute Heart Failure
Treatment With the Ketone Body 3-hydroxybutyrate in Patients With Acute Heart Failure
Background: Acute heart failure is a potentially life-threatening condition, reaching mortality rates of up to 50% in advanced cases.
- Trial name
- KETO-AHF1 (NCT04442555)
- Testing
- HVMN Ketone Ester, Maltodextrin
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Hypertension
Frequent Cuff Inflations May Disrupt the Accuracy of 24-hour Ambulatory Blood Pressure Monitoring
24-hour ambulatory blood pressure monitoring (ABPM) is superior to office blood pressure (BP) for assessing cardiovascular risk.
- Trial name
- NCT04726761
- Testing
- Ambulatory Blood Pressure Monitoring, frequent/non-frequent, Ambulatory Blood Pressure Monitoring, non-frequent/frequent
- Where
- Denmark
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Acute Ischemic Stroke
IDEAL Blood Pressure Management During Endovascular Therapy for Acute Ischemic Stroke
The ideal blood pressure management strategy during endovascular therapy (EVT) for acute ischemic stroke has not been defined. The aim of this pilot randomized clinical trial is to determine whether randomization to a standard…
- Trial name
- IDEAL (NCT04749251)
- Testing
- Individualized blood pressure management, Standard blood pressure management
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Sarcoidosis
Development of the Danish Prospective Sarcoidosis Registry and Baseline Characteristics of a Danish Sarcoidosis Cohort
Development of a Danish Sarcoidosis Registry. Characterization of a cohort of sarcoidosis patients with respect to the baseline epidemiological characteristics, comorbidities, radiology, histopathology, diagnostic investigations…
- Trial name
- NCT04388566
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Aarhus
Stroke
Music Listening for Cardiorespiratory Exercise in Inpatient Stroke Rehabilitation
Stroke survivors struggle to meet clinical recommendations for physical exercise duration and intensity. During the past two decades, music interventions have increasingly shown effectiveness in several motor tasks in stroke…
- Trial name
- NCT05398575
- Testing
- Music
- Where
- Denmark
- Volunteers
- 19 people
- Sponsor
- University of Aarhus
Pregnancy, High Risk
An Adapted Mindfulness-based Stress Reduction Program for Psycho-socially Vulnerable Pregnant Women.
This protocol is for a feasibility study of an adapted mindfulness-based stress reduction (MBSR) program for high-risk pregnant women.
- Trial name
- NCT04571190
- Testing
- Prenatal MBSR
- Where
- Denmark
- Volunteers
- 73 people
- Sponsor
- University of Aarhus
First-time Pregnant Women and Their Partners
The Family Startup Program. A Randomized Controlled Trial of a Universal Group-based Parenting Support Program
The aims of this study are to determine whether a group-based parent support program ("Family Startup") can lead to early improved parental sense of competence, family relations, and child development.
- Trial name
- FIV (NCT02294968)
- Testing
- Family Startup (in Danish: Familieiværksætterne)
- Where
- Denmark
- Volunteers
- 1,719 people
- Sponsor
- University of Aarhus
NAFLD - Non-Alcoholic Fatty Liver Disease, Type 2 Diabetes
Hepatic and Cardiac Metabolic Flexibility in Subjects With T2DM With and Without NAFLD
Non-alcoholic fatty liver disease (NAFLD) covers a spectrum from simple reversible hepatic steatosis to inflammation and fibrosis termed steatohepatitis (NASH) and cirrhosis.
- Trial name
- NCT04698486
- Testing
- Hyperinsulinemic euglycaemic clamp
- Where
- Denmark
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
NAFLD, NASH - Nonalcoholic Steatohepatitis
Splanchnic and Systemic VLDL-TG and FFA Balance
To determine differences between NAFLD and NASH subjects with respect to hepatic FA metabolism (uptake, oxidation, and re-esterification) and hepatic VLDL-TG secretion and peripheral kinetics (oxidation and tissue storage).
- Trial name
- NCT04292977
- Where
- Denmark
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
NAFLD - Nonalcoholic Fatty Liver Disease
Hepatic and Cardiac Metabolic Flexibility in Obese With NAFLD.
Non-alcoholic fatty liver disease (NAFLD) covers a spectrum from reversible hepatic steatosis to inflammation and fibrosis termed steatohepatitis (NASH) and cirrhosis.
- Trial name
- NCT03583437
- Testing
- Exercise
- Where
- Denmark
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
NAFLD - Nonalcoholic Fatty Liver Disease, NASH - Nonalcoholic Steatohepatitis
Effects of Exercise on VLDL-TG Metabolism
Non-alcoholic fatty liver disease (NAFLD) covers a spectrum from reversible hepatic steatosis to inflammation and fibrosis termed steatohepatitis (NASH) and cirrhosis.
- Trial name
- NCT03678727
- Where
- Denmark
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Healthy
The Bioavailability of Red Clover Isoflavones
Previous literature has shown that the molecular form of isoflavones (as aglycones or glycosides) and food matrices can influence the bioavailability of these compounds in humans and hence their efficacy.
- Trial name
- KLBIO (NCT02264223)
- Testing
- Fermented red clover isoflavones in aglycone form, Unfermented glycosides (as aglycone equivalents)
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Insomnia Due to Mental Disorder
Ball Blankets on Insomnia in Depression in Outpatient Clinics
The objective of the study is to examine the efficacy of Protac Ball BlanketsTM (PBB) and specifically if the PBB will extend the total sleep time of patients with insomnia due to depression in two psychiatric outpatient clinics…
- Trial name
- NCT03730974
- Testing
- Protac Ball BlanketTM (7kg Flexible)
- Where
- 2 sites in Denmark
- Volunteers
- 45 people
- Sponsor
- University of Aarhus
Acquired Brain Injury
OPTImized RESTing Environments in Rehabilitation
This study investigates whether an individually designed environment can support and improve the quality of daytime resting periods in in-hospital neurorehabilitation of patients suffering severe acquired brain injury.
- Trial name
- OPTIREST (NCT04500951)
- Testing
- Optimized resting environment, Standard resting environment
- Where
- Denmark
- Volunteers
- 29 people
- Sponsor
- University of Aarhus
Pheochromocytoma, Adrenal Incidentaloma
Effect of Chronic Catecholamine Overproduction on Brown Adipose Tissue
To investigate the effect of catecholamine excess on brown fat. To evaluate the effect of brown fat on energy expenditure and lipid and glucose metabolism
- Trial name
- NCT01949714
- Testing
- Removal of adrenal tumor
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- University of Aarhus
Cardiogenic Shock
Treatment With the Ketone Body 3-hydroxybutyrate in Patients With Cardiogenic Shock
Background Cardiogenic shock is a life-threatening state of acute heart failure with severely depressed blood pressure and organ perfusion. The 30-day mortality is reported as high as 50%.
- Trial name
- KETO-SHOCK1 (NCT04642768)
- Testing
- KetoneAid Ketone Ester, Maltodextrin
- Where
- Denmark
- Volunteers
- 13 people
- Sponsor
- University of Aarhus
Scleroderma, Systemic, Lung Diseases, Interstitial
Functional Exercise Tests in Patients With Systemic Sclerosis
The aim of the study is to examine the validity of peripheral oxygen saturation measurement during the 6-minute walk test in patients with Systemic Sclerosis (SSc) and to examine the utility of two other functional tests as…
- Conditions
- Scleroderma, Systemic, Lung Diseases, Interstitial, Pulmonary Arterial Hypertension, Acroosteolysis
- Trial name
- NCT04650659
- Testing
- 6-minute walk test part one, 6-minute walk test part two, 1-minute sit-to-stand test
- Where
- Denmark
- Volunteers
- 83 people
- Sponsor
- University of Aarhus
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