Clinical trials: sponsored by University of Aarhus
Intraventricular Hemorrhage
ACTIVE Study - Use of ACTIVE Fluid Exchange to Treat Intraventricular Hemorrhage
Randomised controlled trial evaluating active irrigation using IRRAflow device in patients with intraventricular hemorrhages (IVH).
- Trial name
- NCT05204849
- Testing
- IRRAflow, Standard ventriculostomy
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- University of Aarhus
Sleep Apnea, Diabetic Nephropathy Type 2
Sleep Apnea, Coronary Atherosclerosis and Heart Failure in Diabetes Patients With Nephropathy
Background: Diabetes, and especially diabetic kidney disease is associated with the development of cardiovascular disease such as calcification in the coronary arteries and heart failure.
- Conditions
- Sleep Apnea, Diabetic Nephropathy Type 2, Coronary Atheroscleroses, Heart Insufficiency
- Trial name
- SLEEP (NCT04549324)
- Where
- Denmark
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Hyperlactatemia, Healthy
The Role of Lactate in Lipolysis and Catabolism in Humans
Lactate may have anti-lipolytic effects when plasma concentrations of lactate reach levels similar to those seen during high intensity exercise.
- Conditions
- Hyperlactatemia, Healthy, Lactate
- Trial name
- LILACH (NCT04710875)
- Testing
- Na-lactate, Sodium chloride
- Where
- 2 sites in Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Hypoparathyroidism, Pseudo Hypoparathyroidism
QoL and Cognitive Function in Patients With Hypoparathyroidism
Hypoparathyroidism (HypoPT) is a disease with inadequate production of parathyroid hormone (PTH) from the parathyroid glands leading to hypocalcemia.
- Trial name
- MR-hypoPT (NCT04569604)
- Testing
- MRI scans, Neuro cognitive tests, Questionnaires on Quality of Life
- Where
- Denmark
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Energy Intake, Activities of Daily Living
Impact on Energy Intake by Implementing Recommended Food Texture Through Dietary Guidance
An intervention study on the effect of dietary guidance with focus on implementing recommended food texture, at the department of Eating and Swallowing difficulties, Region Midtjylland, Denmark.
- Conditions
- Energy Intake, Activities of Daily Living, Quality of Life, Protein Intake
- Trial name
- NCT04655547
- Testing
- Dietary guidance
- Where
- Denmark
- Volunteers
- 13 people
- Sponsor
- University of Aarhus
Cervical Cancer Screening
Community-based Intervention for Cervical Cancer Screening Uptake in Nepal
This study aims to evaluate the effect of a Female Community Health Volunteer (FCHV) led community-based educational intervention through home visits increasing cervical cancer screening uptake.
- Trial name
- COBIN-C (NCT03808064)
- Testing
- FCHV home visit
- Where
- Nepal
- Volunteers
- 690 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Heart Failure, Systolic, Ketonemia
Effects of Ketones and Niacin in Heart Failure Patients
Ketones, 3-hydroxybutyrate (3-OHB), have shown to have beneficial hemodynamics effect in patients with hearth failure with reduced ejection fraction.
- Trial name
- KETO-COX (NCT04703361)
- Testing
- Niacin, Na-3-OHB
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Primary Brain Tumour, Radiation Toxicity
Cognitive Function After Radiation Therapy for Primary Brain Tumours
This study will assess cognitive function in patients with a primary brain tumour treated with radiation therapy (RT) to generate radio-sensitivity and volume effect parameters for the development of cognitive dysfunction.
- Conditions
- Primary Brain Tumour, Radiation Toxicity, Cognitive Impairment
- Trial name
- NCT04306432
- Testing
- Cognitive tests and Patient Reported Outcomes
- Where
- 5 sites in Denmark
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pulmonary Hypertension, Ketonemia
Ketones for Pulmonary Hypertension - Effects on Hemodynamics
In the present study, patients with idiopathic pulmonary hypertension (IPAH) and chronic thromboembolic pulmonary hypertenion will be investigated in a randomized cross-over design with ketone infusions and placebo.
- Trial name
- KEPAH (NCT04615754)
- Testing
- Hyperketonemia - use of ketone (3-OHB) infusion
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Hepatocellular Carcinoma
SBRT or TACE for Advanced HCC
Randomized study of stereotactic body radiation therapy (SBRT) versus transarterial chemoembolization (TACE) in locally advanced hepatocellular carcinoma.
- Trial name
- NCT03338647
- Testing
- DEB, SBRT
- Where
- India
- Volunteers
- 180 people
- Sponsor
- University of Aarhus
Physiological Stress Responses to Standardises Stress Situations, Psychological Responses to Standardised Stress Situations
Effects of Contact to Dogs During Stressful Situations
The investigators will conduct an experimental study comparing responses of healthy participants in two test situations where they are subjected to mild stress.
- Conditions
- Physiological Stress Responses to Standardises Stress Situations, Psychological Responses to Standardised Stress Situations, Behavioural Responses to Standardised Stress Situations
- Trial name
- NCT04866173
- Testing
- Dog, No Dog
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Physiological Responses to Contact With Dogs, Psychological Responses to Contact With Dogs
Measuring Effects of Contact to Dogs
The study aims to identify and quantify objective non-invasive measures of the immediate effect of contact with dogs in a standardized experimental setup.
- Conditions
- Physiological Responses to Contact With Dogs, Psychological Responses to Contact With Dogs, Behavioural Responses to Contact With Dogs
- Trial name
- NCT04696419
- Testing
- Different intensities of contact to dogs
- Where
- Denmark
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Frailty
Effect of a Transitional Care Intervention
The objective of this study is to evaluate the effect of a transitional care intervention on readmissions among older medical patients. The proportion of older people is rapidly growing.
- Trial name
- NCT04796701
- Testing
- Follow-Home-intervention
- Where
- Denmark
- Volunteers
- 1,266 people
- Sponsor
- University of Aarhus
Cesarean Section; Infection, Catheter-Related Infections
Caesarean Delivery With or Without an Indwelling Bladder Catheter. A Randomised Trial.
The aim of this study is to compare the incidence of catheter associated culture-based urinary tract infection (UTI) after elective CD with or without preoperative placement of a urinary catheter.
- Trial name
- NCT03479931
- Testing
- Without placement of a catheter, With placement of a catheter
- Where
- Denmark
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pregnancy, Parturition
The Influence of Antenatal Classes on Pregnancy, Birth and Parenthood
1. To study the influence of antenatal classes for first time parents and their effect ob pregnancy, birth and parenthood. 2. Randomized into two groups (a. 3 courses in midpregnancy and b. no courses) 3.
- Trial name
- NCT00323401
- Testing
- Antenatal classes
- Where
- 2 sites in Denmark
- Volunteers
- 1,192 people
- Sponsor
- University of Aarhus
Esophageal Neoplasms, Thrombosis
Thromboprophylaxis in Oesophageal Cancer Patients
The purpose of the study is to examine the efficacy and safety of prolonged thromboprophylactic treatment with Fragmin® in oesophageal cancer patients undergoing intended curative surgery.
- Conditions
- Esophageal Neoplasms, Thrombosis, Thromboembolism
- Trial name
- TOP-RCT (NCT05067153)
- Testing
- Fragmin 5000 UNT in 0.2 ML Prefilled Syringe
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Uterine Cervical Neoplasms
Urinary and Vaginal HPV Testing in Cervical Cancer Screening
Cervical cancer, caused by high-risk human papillomavirus (HPV) infection, poses a problem worldwide as it is the fourth most common female cancer.
- Trial name
- NCT05065853
- Testing
- urine self-sampling group, clinician-collected cervical sample group
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Giant Cell Arteritis, Vasculitis
Evaluation of Ultrasound and PET/CT in the Diagnosis and Monitoring of Giant Cell Arteritis
The aim of this project is to prospectively evaluate the diagnostic accuracy of different imaging tools in specific giant cell arteritis disease subsets before and after treatment initiation.
- Trial name
- NCT03765424
- Testing
- Ultrasound
- Volunteers
- 101 people
- Sponsor
- University of Aarhus
Pain, Chronic, Breast Cancer
Optimizing Psychological Treatment for Pain After Breast Cancer: A Pilot Study
The present study is a pilot study that aims to evaluate the feasibility, validity, and preliminary efficacy of three psychological treatment components for pain after breast cancer, which will be evaluated in a larger trial…
- Trial name
- NCT04841928
- Testing
- Mindful attention, Decentering, Value-based action
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- University of Aarhus
Colorectal Neoplasms
Optimising Colorectal Cancer Screening Participation
The aim of this study is to demonstrate the effectiveness of three and four-staged invitation procedures compared to two-staged procedures by combining pre-notifications and reminders.
- Trial name
- NCT04292366
- Testing
- Invitation procedure
- Where
- Denmark
- Volunteers
- 60,000 people
- Sponsor
- University of Aarhus
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