Clinical trials: sponsored by University of Aarhus
Ischemic Heart Disease, Myocardial Infarction
Polyamine Treatment in Elderly Patients With Coronary Artery Disease
The present study is testing spermidine treatment in elderly patients with coronary artery disease. The study is a randomized, double-blind, placebo-controlled, two-armed, parallel-group, single centre, clinical study.
- Conditions
- Ischemic Heart Disease, Myocardial Infarction, Cardiovascular Diseases, Hypertensive Heart Disease
- Trial name
- PolyCAD (NCT06186102)
- Testing
- Spermidine
- Where
- Denmark
- Volunteers
- 187 people
- Sponsor
- University of Aarhus
Soft Tissue Sarcoma of the Trunk and Extremities, Sarcoma
Fluorescence-Guided Optimization of Sarcoma Margins
This is a Danish national multicenter prospective cohort study to evaluate if fluorescence-guided surgery (FGS) using indocyanine green (ICG) can reduce the rate of positive margins following sarcoma resection.
- Trial name
- FOCUS (NCT07134192)
- Testing
- Fluorescent-guided Surgery
- Where
- 2 sites in Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
Distal Radius Fracture, Colles Fracture
Wrist Injury Strengthening Exercise (WISE) Versus Usual Care Advice for Improving Pain and Function
The goal of this clinical trial is to find out whether a therapist-guided exercise program helps people aged 50 and older recover better, in terms of pain and function, after a wrist fracture, compared to the usual care advice…
- Conditions
- Distal Radius Fracture, Colles Fracture, Wrist Fracture, Wrist Fractures
- Trial name
- WISE-DK (NCT07538323)
- Testing
- Supervised Exercise, Usual Care
- Where
- Denmark
- Volunteers
- 588 people
- Sponsor
- University of Aarhus
Type 1 Diabetes, Hyperglycemia Stress
Competition Induced Hyperglycemia in Athletes With Type 1 Diabetes
Design and methods 12 athletes with T1D and 12 healthy athletes are included in a prospective experimental randomized, cross-over study.
- Trial name
- EXCITE-1 (NCT05561517)
- Testing
- 5 K running
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Type1diabetes, Hypoglycemia
Galactose - the Ideal Carbohydrate Supplement for Exercise in Type 1 Diabetes
In this study, 14 subjects with type 1 diabetes are studied in a randomized crossover study in which the subjects cycle at a fixed intensity at 60% of their maximum oxygen capacity (VO2 max) for 1 hour.
- Conditions
- Type1diabetes, Hypoglycemia, Hyperglycemia
- Trial name
- NCT05557227
- Testing
- 1-hour cycling
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- University of Aarhus
Type1diabetes
Morning Versus Afternoon Aerobic Exercise in Type 1 Diabetes
Aim. To determine whether the need for exogenous carbohydrate supplementation during exercise in type 1 diabetes is lower during morning exercise compared to afternoon exercise, and whether this is associated with greater lipid…
- Trial name
- NCT06115616
- Testing
- Morning exercise, Afternoon exercise
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Hip Fracture, Anemia
IRONCARE: Iron Treatment in Older Patients With Hip Fractures
The aim of this study is to investigate the effects of intravenous (IV) iron therapy compared to alternate-day oral iron treatment and no supplementation in older patients with hip fractures.
- Conditions
- Hip Fracture, Anemia, Iron, Placebo - Control
- Trial name
- NCT07659184
- Testing
- Ferric Derisomaltose, Oral Iron (Ferrous sulphate)
- Where
- 5 sites in Denmark
- Volunteers
- 528 people
- Sponsor
- University of Aarhus
Parkinson's Disease (PD), Spinal Cord Stimulation (SCS)
Trial of Four Spinal Cord Stimulation Paradigms for Gait Impairment in Parkinson's Disease
Patients with PD and SCS treatment for gait impairment entered a cross-over trial of four stimulation paradigms; high frequency/low pulse width, low frequency/high pulse width, Fast-Acting Sub-perception Therapy, and MicroBurst.
- Trial name
- NCT07659405
- Testing
- Stimulation paradigm: High frequency / low pulse width, Stimulation paradigm: Low frequency / high pulse width, MicroBurst
- Where
- Denmark
- Volunteers
- 11 people
- Sponsor
- University of Aarhus
Neoplasms, Anxiety
Effects of a Lay-led Anxiety and Depression Self-management Program for Cancer Patients
The investigators aim to evaluate a peer-to-peer patient self-management program targeting symptoms of anxiety and depression in a randomized trial.
- Conditions
- Neoplasms, Anxiety, Self Efficacy, Psychological Distress
- Trial name
- ADSMP-C (NCT04537195)
- Testing
- ADSMP-C
- Where
- 2 sites in Denmark
- Volunteers
- 234 people
- Sponsor
- University of Aarhus
Acromegaly
ACRODAT Prospective Evaluation Study
ACRODAT® is a new software medical device developed by a group of acromegaly experts to help practising endocrinologists assess disease activity in patients with acromegaly.
- Trial name
- NCT04349839
- Testing
- Acrodat software
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- University of Aarhus
Lung Abscess
Transthoracic Drainage of Lung Abscesses. A National Randomized Trial.
This study aims to investigate if early drainage of lung abscesses, in addition to standard antibiotic treatment, leads to shorter length of hospital stay. Study Design This is a randomized, controlled clinical trial.
- Trial name
- TOLA (NCT07247461)
- Testing
- Transthoracic drainage
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- University of Aarhus
Type 1 Diabetes
Individualized Exercise Consultation in Type 1 Diabetes
People with type 1 diabetes often experience challenges managing blood glucose levels during and around physical activity, which may reduce participation in exercise.
- Trial name
- ACTIVE-T1D (NCT07596160)
- Testing
- Exercise consultations
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Functional Gastrointestinal Disorders (FGID)
Internet-delivered Psychological Treatment of Functional Gastrointestinal Disorders
Brief Summary Functional gastrointestinal disorders (FGID), including irritable bowel syndrome (IBS), are common conditions characterized by recurrent gastrointestinal symptoms that cannot be fully explained by structural…
- Trial name
- NCT07636122
- Testing
- I-CBT
- Volunteers
- 30 people
- Sponsor
- University of Aarhus
Urinary Incontinence in Children
Efficacy of Solifenacin, Mirabegron and Combination Therapy in Children With Daytime Urinary Incontinence (BeDry)
The primary objective is to evaluate if (1) combination therapy of solifenacin and mirabegron in low doses is superior to monotherapy of solifenacin in high dose and if (2) combination therapy of mirabegron and solifenacin in low…
- Trial name
- NCT06551246
- Testing
- Solifenacin, Mirabegron
- Where
- 5 sites in Denmark
- Volunteers
- 236 people
- Sponsor
- University of Aarhus
Urinary Incontinence in Children
Strategy for Withdrawal of Pharmacological Treatment for Urinary Incontinence in Children (StayDry)
The primary objective is to investigate if abrupt withdrawal versus gradual withdrawal of pharmacotherapy (solifenacin and/or mirabegron) influences the risk of recurrence of incontinence.
- Trial name
- NCT06465576
- Testing
- Solifenacin, Mirabegron, Solifenacin + Mirabegron
- Where
- 5 sites in Denmark
- Volunteers
- 216 people
- Sponsor
- University of Aarhus
Medical Education, Simulation, Crisis Resource Management, Simulation Training
Using Simulation-based Team Training to Improve Psychological Safety and Relational Coordination as Well as Conducting a Process Evaluation
Simulation-based team training is increasingly used in hospitals to support teamwork and communication, particularly in situations that are complex or time-critical.
- Conditions
- Medical Education, Simulation, Crisis Resource Management, Simulation Training, Simulation Based Medical Education, Culture
- Trial name
- InfecSIM (NCT07381270)
- Testing
- Simulation-based team training
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Schizophrenia Disorders, Personality Disorders
Recovery in Telling Life Stories
This project tests the Recovery In Telling Life Stories (RETELL) intervention, aimed at supporting personal recovery in people with severe mental illness (SMI).
- Conditions
- Schizophrenia Disorders, Personality Disorders, Obsessive - Compulsive Disorder, Anxiety Disorders
- Trial name
- RETELL (NCT07082777)
- Testing
- Narrative therapy
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Hip Dysplasia
Is Periacetabular Osteotomy Superior to Progressive Resistance Training?
The primary aim of this study is to examine if Periacetabular Osteotomy (PAO) followed by 4 months of usual care followed by 8 months of progressive resistance training (PRT) is superior to 12 months of a PRT intervention in…
- Trial name
- NCT03941171
- Testing
- PAO, Usual care after PAO, PRT
- Where
- 3 sites in Denmark, Norway
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Occupational Injuries, Occupational Exposure
The Effect of Intelligent Exercise and Ergonomic Recommendations on Surgeon Musculoskeletal Discomfort
The goal of this clinical trial is to investigate the effects of Intelligent Physical Exercise Training (IPET) and ergonomic recommendations on musculoskeletal pain among abdominal and pelvic surgeons.
- Trial name
- NCT06112106
- Testing
- Intelligent Physical Exercise Training (IPET)
- Where
- 7 sites in United States, Denmark
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (ICD-10 G93.3)
Investigating the Effects of Intermittent Hypoxia-Hyperoxia Treatment (IHHT) in People With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) to Improve Fatigue, Pain, and Quality of Life by Targeting Mitochondrial Dysfunction and Autonomic Nervous System Impairment
This study is testing a new treatment for people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and long-term symptoms after COVID-19.
- Trial name
- REenergizeME (NCT07317401)
- Testing
- Intermittent hypoxia-hyperoxia treatment (IHHT)
- Where
- Denmark
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
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