Clinical trials: sponsored by University of Aarhus
Breast Neoplasms, Endothelial Dysfunction
Anticancer Treatment of Breast Cancer Related to Cardiotoxicity and Dysfunctional Endothelium
Several cytotoxic regimens are related to endothelial cell damage and vascular toxicity. Endothelial dysfunction is implicated in the pathogenesis of all known cardiovascular diseases (CVD) and closely related to the metabolic…
- Conditions
- Breast Neoplasms, Endothelial Dysfunction, Cardiovascular Disease, Metabolic Syndrome
- Trial name
- ABCDE (NCT02652975)
- Testing
- Venous occlusion plethysmography, SphygmoCor, 24hour blood pressure
- Where
- Denmark
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Frail Elderly Syndrome
Validation of a Record-based Frailty Assessment According to the Multidimensional Prognostic Index
Background Various phenotype and cumulative frailty assessment tools have been developed and compared in research. For use in an in-hospital setting, a cumulative and graded frailty assessment method is preferred in order to…
- Trial name
- NCT03794674
- Testing
- No intervention.
- Where
- Denmark
- Volunteers
- 92 people
- Sponsor
- University of Aarhus
Chronic Obstructive Pulmonary Disease, COPD
Tele Health Monitoring Service for Patients With Chronic Obstructive Pulmonary Disease
The aim of this study is to evaluate the effect of monitoring patients with chronic obstructive pulmonary disease (COPD) after a hospitalization for COPD exacerbation or pneumonia.
- Trial name
- NCT02615795
- Testing
- Tele Monitoring, using Tunstall monitoring device
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- University of Aarhus
Pes Planovalgus
New Bone Grafting Technique in Paediatric Foot Surgery. Validation of Outcome Measures
The purpose of this study is to determine whether structural calcium ceramic bone graft substitute (ReproBone™) is non-inferior compared to autologous tricortical iliac crest bone graft in lateral calcaneal lengthening…
- Trial name
- NCT01770574
- Testing
- ReproBone, calcaneal lengthening
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Primary Hyperparathyroidism
Effect of Parathyroidectomy on Cardiovascular Health
The aim of this study is to establish whether patients with mild primary hyperparathyroidism (PHPT) have an increased risk of cardiovascular diseases.
- Trial name
- NCT02989428
- Testing
- Early parathyroidectomy group (EPTX-group)
- Where
- Denmark
- Volunteers
- 69 people
- Sponsor
- University of Aarhus
Diabetes, Gestational
Effect of Carbohydrate Distribution on Blood Glucose in Women With Gestational Diabetes Mellitus (GDM)
This study aims to investigate whether high-morning carbohydrate intake (HMK) compared with low-morning carbohydrate intake (LMK) affects glycemic variability in GDM patients based on Continuous glucose monitoring (CGM).
- Trial name
- NCT03835208
- Testing
- High/low carbohydrate distribution
- Where
- 2 sites in Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
Diabetes, Gestational
Insulin Sensitivity and Secretion During Pregnancy and Post Partum in Women With Gestational Diabetes.
Aim of the study: To define insulin requirement during pregnancy and to identify the rapid changes in insulin sensitivity around parturition and the first 6 months post partum.
- Trial name
- NCT02770079
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Estrogen Supplementation
The Anabolic Effects of Estrogen on Skeletal Muscles
Purpose: to study the effect of estrogen replacement on muscle hypertrophy in response to 12 weeks resistance training in postmenopausal women Hypothesis: Transdermal administration of 17-β estradiol enhance the anabolic effect…
- Trial name
- ESTRO (NCT03020953)
- Testing
- Exercise + Estrogen
- Where
- Denmark
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Diabetes Mellitus Type I, Hypoglycemia
Intracellular Counter-regulatory Mechanisms Following Low Blood Glucose
Diabetes mellitus type I (DMI) is characterized by lack of endogenous insulin and these patients are 100% dependent on insulin substitution to survive.
- Trial name
- NCT01919788
- Testing
- Insulin (Insuman Rapid), Glucose, Saline
- Where
- Denmark
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Whiplash Injuries
Effectiveness of an Educational Video Following Acute Whiplash Trauma
The purpose of this study is to examine the effect of an educational video on intensity of neck pain, disability, illness perceptions and work ability following acute whiplash trauma caused by motor vehicle accidents.
- Trial name
- NCT01699334
- Testing
- Psychoeducational video, Relaxation video
- Where
- Denmark
- Volunteers
- 269 people
- Sponsor
- University of Aarhus
Growth Hormone Deficiency, Growth Hormone Treatment
Effects of Growth Hormone and IGF-1 on Anabolic Signals and Stem Cell Recruitment in Human Skeletal Muscle
12 adult hypopituitary patients with newly diagnosed Growth hormone (GH)-deficiency will be studied two times. The first examinations will be performed shortly after time of diagnose before initiation of exogenous GH treatment…
- Trial name
- NCT03878992
- Testing
- Genotropin miniquick 0.5 mg, injection
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Brain Concussion, Post-Concussion Syndrome
Early Intervention Programme for Young Patients (Aged 15 - 30 Years) With Symptoms Following Concussion.
Background: Five - 15 % of patients with concussion continue to experience impairing physical, cognitive and emotional symptoms longer than 3 months post-injury.
- Trial name
- NCT02337101
- Testing
- Enhanced Usual Care (EUC), EUC + Early intervention programme
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- University of Aarhus
Healthy
Oral Contraceptive and Strength Training
Cross sectional study investigating the effect of strength training in users and non-users of oral contraceptives (OC) (2nd generation OC)
- Trial name
- NCT03374878
- Testing
- no oral contraceptive and training, oral contraceptive and training
- Where
- Denmark
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Ventricular Septal Defect
Cardiopulmonary Function in Adults Born With a Ventricular Septal Defect
The overall objective for this study is to evaluate the cardiopulmonary function of VSD-patients compared with healthy age- and gender-matched controls.
- Trial name
- NCT03684161
- Testing
- Cardiopulmonary function
- Where
- Denmark
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Femoracetabular Impingement
Arthroscopic Treatment of Patients in Horsens and Aarhus With FemoroAcetabular Impingement: the HAFAI-cohort
Purpose: The aim of this prospective cohort is to evaluate patients before, 6 and 12 months after arthroscopic surgery for FAI and compare the results to people without hip problems.
- Trial name
- NCT02306525
- Testing
- Arthroscopic surgery of the hip joint
- Where
- 3 sites in Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Klinefelter Syndrome, Thrombosis
Thrombosis and Neurocognition in Klinefelter Syndrome
The haemostatic balance and neurocognitive capability of men with Klinefelter syndrome is compared to healthy controls by using specific biochemical assays for coagulation and fibrinolysis and a selection of neuropsychological…
- Trial name
- NCT02526628
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Depression
The Antidepressant Effect of Right Prefrontal Low Frequency rTMS in an Accelerated Treatment Model
Repetitive transcranial magnetic stimulation has appeared a new non-invasive antidepressant method, which implies non-convulsive focal stimulation of the prefrontal cortex of the brain through a time varying magnetic field.
- Trial name
- NCT03868774
- Testing
- repetitive transcranial magnetic stimulation
- Sponsor
- University of Aarhus
Infertility
The Role of Extracellular pH on Spermatozoa's Directional Movement in Vitro
The purpose of this research project is to determine whether or not the directional movement of spermatozoa is influenced by a pH gradient by examining spermatozoa in vitro.
- Trial name
- NCT03574714
- Testing
- Extracellular pH
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Protein Metabolism
Optimal Protein Dose Per Meal During Weight Loss in Perspective to Maintaining Muscle Mass
The primary aim of the trial is to determine the optimal dose of protein per meal in relation to enhancing muscle protein synthesis and thereby in perspective counteract muscle loss during weight loss.
- Trial name
- NCT03326284
- Testing
- 15 g protein hypocaloric, 35 g protein hypocaloric, 60 g protein hypocaloric
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Social Anxiety Disorder
Cognitive Behavioral Therapy for Adolescents With Social Anxiety Disorder
The main aim of the present study is to investigate the effectiveness of a disorder specific group cognitive behavior therapy (G-CBT) program for youth SAD, the, Cool Kids Anxiety Program - Social Enhanced (CK-E), developed at…
- Trial name
- NCT03986827
- Testing
- Cool Kids Anxiety Program - Social Enhanced, Cool Kids Anxiety Program
- Where
- Denmark
- Volunteers
- 96 people
- Sponsor
- University of Aarhus
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