Clinical trials: sponsored by University of Aarhus
Gastrointestinal Disease
Casein Glycomacropeptide in Healthy Subjects
Casein glycomacropeptide (CGMP) has anti-inflammatory properties in experimental rodent colitis and using human in vitro inflammation models. Its use as a food ingredient has proven safe and with no influence on dietary intake.
- Trial name
- NCT02832700
- Testing
- Casein glycomacropeptide
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Reperfusion Injuries, Myocardial
The Role of Mitochondrial Respiration in the Cardioprotective Capacity of IPC in Diabetic and Non-diabetic Patients
The overall aim of this study is to examine the role of mitochondrial respiration in human diabetic tissue before and after ischemia.
- Trial name
- NCT02993484
- Testing
- Dimethyl Malonate, Ischemic preconditioning, Ischemia reperfusion
- Volunteers
- 39 people
- Sponsor
- University of Aarhus
Major Depressive Disorder, Recurrent
Mechanisms of Mindfulness-Based Cognitive Therapy in the Treatment of Recurrent Major Depressive Disorder
The primary purpose of this study is to investigate neural mechanisms and predictors of treatment outcome in Mindfulness-Based Cognitive Therapy (MBCT) for recurrent Major Depressive Disorder.
- Trial name
- NCT03353493
- Testing
- MBCT, TAU
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Pain Management
MBCT for Cancer Patients in Follow-Up
The objectives of the present study are: 1) to executing the practical implementation in an oncology department of MBCT for patients who have completed their primary treatment and experience significant cancer- and…
- Trial name
- NCT03591237
- Testing
- Mindfulness-Based Cognitive Therapy
- Where
- 2 sites in Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Alcoholic Hepatitis
The Effect of Gut Sterilisation on Macrophage Activation in Patients With Alcoholic Hepatitis.
Alcoholic hepatitis (AH) is a severe alcohol induced hepatic inflammation that leads to jaundice and liver failure. Gut derived bacterial translocation to the liver is currently thought to be one of the main inflammatory drivers…
- Trial name
- NCT03157388
- Testing
- Combined Vancomycin and Gentamycin and Meropenem
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
Collagen Protein
Effects of Collagen Protein on the Amino Acid Profile of the Blood
This project aims to investigate the absorption of enzymatically hydrolysed and non-enzymatically hydrolysed collagen on the Amino acid profile of the blood
- Trial name
- NCT03749239
- Testing
- Collagen protein
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Gestational Diabetes
The Acute Effect of Physical Activity on Blood Glucose in Pregnant Women
The aim of the project is to investigate the acute effect of exercise on blood glucose after glucose consumption. Thereby we wish to achieve knowledge that can improve prevention and treatment of gestational overweight and…
- Trial name
- NCT03644238
- Testing
- Oral Glucose Tolerance Test, Inactivity, Physical activity
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Geriatric Disorder
Early Geriatric Follow-up in Older Acute Medical Patients
The study is a quasi-randomized controlled trial conducted in a Danish University Hospital including older patients admitted to Emergency Department (ED).
- Trial name
- NCT02664948
- Testing
- Early geriatric follow-up after discharge
- Where
- Denmark
- Volunteers
- 2,362 people
- Sponsor
- University of Aarhus
Geriatric Assessment, Cancer
Effect of Comprehensive Geriatric Assessment on Short-time Mortality in Elderly Cancer Patients
Older cancer patients referred to Oncology outpatient Clinic at Aarhus University Hospital have for a period been offered Comprehensive geriatric Assessment (CGA) as part of a routine practice.
- Trial name
- NCT03814213
- Testing
- CGA, tailored care
- Where
- 2 sites in Denmark
- Volunteers
- 781 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Urinary Tract Infections, Cesarean Section; Infection
Caesarean Delivery With or Without an Indwelling Bladder Catheter
The aim of this study is to compare the incidence of catheter associated culture-based urinary tract infection (UTI) after elective CD with or without preoperative placement of a urinary catheter.
- Trial name
- NCT03672214
- Testing
- Without placement of indwelling catheter, With placement of indwelling catheter
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Non-small-cell Lung Cancer, Radiation Pneumonitis
Role of SPECT in Radiotherapy of Lung Cancer and Toxicity Evaluation
Overall objective of the study is to compare the use of SPECT in radiotherapy treatment planning with standard CT-based radiotherapy for stage I-III non-small-cell lung cancer patients
- Trial name
- NCT01745484
- Testing
- SPECT-based treatment plan
- Where
- Denmark
- Volunteers
- 71 people
- Sponsor
- University of Aarhus
Pain, Postoperative
Popliteal Plexus Block for Total Knee Arthroplasty
This study aims to assess the analgesic effect of the popliteal plexus block as a supplement to a femoral triangle block in patients undergoing total knee arthroplasty
- Trial name
- NCT03439787
- Testing
- Bupivacaine-EPINEPHrine 0.5%-1:200,000 Injectable Solution, Sodium Chloride 0.9 %
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
Muscle Protein Synthesis, Endotoxemia
Whey vs Casein to Combat Post-inflammatory Protein and Muscle Waste in Acute Disease
This study compares three different protein supplements (casein, whey and leucine-enriched whey) and their effect on post-inflammatory muscle waste in a model of acute disease.
- Conditions
- Muscle Protein Synthesis, Endotoxemia, Nutrition, Milk Protein
- Trial name
- NCT03319550
- Testing
- Casein, Whey, Leucine-enriched whey
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Psoriasis
The PsoTeenQOL - Preliminary Reliability and Validity
This study aims to develop and provide preliminary reliability and validity of a questionnaire to measure Health-related Quality of Life (HRQOL) in adolescents with psoriasis.
- Trial name
- NCT03358914
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 233 people
- Sponsor
- University of Aarhus
Traumatic Brain INjury
Prognostic Potential of Prehospital Biomarkers in TBI Patients
The PreTBI III study aims to investigate the prognostic potential of prehospital and repeated in-hospital S100B, NSE and GFAP measurements as predictors of neurological outcome in patients suffering severe TBI.
- Trial name
- PreTBI III (NCT03062566)
- Testing
- Blood sampling
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- University of Aarhus
Traumatic Brain INjury
Biomarkers in Prehospital Prediction of Need for Neurosurgical Observation or Intervention in TBI Patients
The PreTBI II study aims to investigate the diagnostic potential of prehospital S100B and GFAP measurements in prediction of need for neurosurgical observation and/or intervention in moderate TBI patients, to rule-in high-risk…
- Trial name
- PreTBI II (NCT03028376)
- Testing
- Blood sampling
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- University of Aarhus
Celiac Disease, Infertility
Celiac Disease and Infertility Among Men and Women in Denmark
The purpose of this study is to estimate the prevalence of celiac disease in a population of men and women newly referred to fertility treatment in Danish public fertility clinics.
- Trial name
- CØF2015 (NCT02451449)
- Where
- 2 sites in Denmark
- Volunteers
- 900 people
- Sponsor
- University of Aarhus
Traumatic Brain Injury
Biomarkers in Prehospital Rule-out of Intracranial Lesions in TBI Patients
The PreTBI I study will investigate whether prehospital blood samples drawn already in the ambulance can rule-out intracranial lesions in patients suffering head trauma.
- Trial name
- PreTBI I (NCT02867137)
- Testing
- Blood sampling
- Where
- Denmark
- Volunteers
- 595 people
- Sponsor
- University of Aarhus
Retinal Ischemia, Diabetes Complications
Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning in Patients With Type 1 Diabetes
Remote ischemic conditioning (RIC) is a therapeutic strategy for protecting organs or tissue against the detrimental effects of acute ischemia-reperfusion injury.
- Conditions
- Retinal Ischemia, Diabetes Complications, Ischemia, Diabetes Mellitus, Type 1
- Trial name
- NCT03906383
- Testing
- Remote Ischemic Conditioning
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- University of Aarhus
Interstitial Lung Disease, Dyspnea
Palliation of Dyspnea With Morphine in Patients With Interstitial Lung Disease
36 patients with interstitial lung disease will be randomized to 1 weeks treatment with morphine hydrochloride as oral linctus 5 mg, four times a day, and 5 mg as needed up to 4 times a day, or corresponding doses of placebo.
- Conditions
- Interstitial Lung Disease, Dyspnea, Morphine
- Trial name
- MORPHILD (NCT02622022)
- Testing
- Morphine hydrochloride
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- University of Aarhus
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