Clinical trials: sponsored by University of Aarhus
Bladder Cancer, Non-Muscle-Invasive Bladder Cancer (NMIBC)
Supporting Sexual Health in Bladder Cancer Patients: A Sequential Mixed-Methods Intervention Study
Despite increasing recognition of sexual dysfunction and sexual distress as important survivorship issues in oncology, research and clinical attention remain uneven across cancer types.
- Conditions
- Bladder Cancer, Non-Muscle-Invasive Bladder Cancer (NMIBC), Muscle-Invasive Bladder Carcinoma
- Trial name
- SPICE (NCT07339761)
- Testing
- Sexological Support
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- University of Aarhus
Osteoarthritis, Knee, Patellofemoral Knee Arthroplasty
Study of Knee Replacements for Patellofemoral Osteoarthritis
This is a randomized comparison of PFA and TKR in treatment of isolated patellofemoral osteoarthritis.
- Trial name
- PFA/TKR (NCT01326156)
- Testing
- Knee arthroplasty
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Sex Chromosome Disorders
Clinical and Genetic Aspects of Fetuses With Sex-chromosome Disorders
To conduct a comprehensive clinical investigation of electively aborted fetuses with sex chromosome disorders and their placentas, in parallel with analyses of epigenetic alterations and changes in gene expression in these…
- Trial name
- NCT07304193
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- University of Aarhus
ADL
Effect of Intensified Occupational Therapy on Basic Activities of Daily Living
The objective is to investigate the effect of an intensified occupational therapy intervention on independence in basic activities of daily living (ADL) in subjects with stroke
- Trial name
- NCT05638607
- Testing
- Intensified occupational therapy
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Sleep Deprivation, Circadian Rhythm
Circadian Rhythms and Time Perception in Healthy Adults During Constant Wakefulness
This study examines how the internal body clock (circadian rhythms) influences the way healthy adults experience time, think, and feel when they stay awake for an extended period.
- Conditions
- Sleep Deprivation, Circadian Rhythm, Healthy Volunteers, Time Perception
- Trial name
- CircaTime (NCT07294781)
- Testing
- Constant Routine Wakefulness
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Circadian Rhythm, Time Perception
Circadian Timing and Time Perception in Healthy Adults
This study examines how a person's natural daily rhythm ("chronotype") affects the way time is experienced and judged. Healthy Danish-speaking adults (23-45 years) who are clearly morning-type or evening-type will complete two…
- Trial name
- ChronoTime (NCT07292597)
- Testing
- Session timing relative to chronotype
- Where
- Denmark
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Renal Artery Obstruction, Hypertension, Renovascular
A Prospective Danish National Registry of PTRA in Patients With Renovascular Hypertension
A prospective Danish national registry of percutaneous transluminal renal angioplasty (PTRA) in high-risk patients with renal artery stenosis selected on the basis of common national criteria, and with a common follow-up protocol…
- Conditions
- Renal Artery Obstruction, Hypertension, Renovascular, Cardiovascular Diseases, Kidney Diseases
- Trial name
- DAN-PTRA (NCT02770066)
- Testing
- Percutaneous transluminal renal angioplasty
- Where
- 5 sites in Denmark
- Volunteers
- 160 people
- Sponsor
- University of Aarhus
Progressive Fibrosing Interstitial Lung Disease
Hyperpolarized 129-Xenon MRI in Fibrosing Interstitial Lung Disease
This project aims to investigate the potential of non-invasive imaging to identify and monitor the earliest signs and physiological effects of pulmonary fibrosis and resulting cardiac dysfunction in patients with fibrosing…
- Trial name
- NCT05914506
- Testing
- Hyperpolarized xenon-129 MRI
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- University of Aarhus
Depression, Anxiety
Combining Treatment Components in Transdiagnostic Therapy for Anxiety and Depression
The present study is a randomized controlled trial that will evaluate the effect of combining two treatment components (i.e., cognitive restructuring and detached mindfulness) drawn from cognitive behavioral therapies (CBTs) that…
- Trial name
- NCT06429956
- Testing
- Mindful emotion awareness, Cognitive flexibility
- Where
- Denmark
- Volunteers
- 93 people
- Sponsor
- University of Aarhus
EBV Infection, EBV Viremia
EVITA Study - Epstein-Barr Virus Infection moniToring in renAl Transplant Recipients
Transplant recipients are treated with immunosuppressive drugs to avoid rejection of the transplanted organ. As the medication impairs the immune response, it also increases the risk of serious infections and cancer in transplant…
- Conditions
- EBV Infection, EBV Viremia, Epstein-Barr Virus Associated Lymphoproliferative Disorder, Post-transplant Lymphoproliferative Disorder
- Trial name
- EVITA (NCT04189835)
- Testing
- EBV DNA in whole blood and plasma
- Where
- 3 sites in Denmark, Norway
- Volunteers
- 509 people
- Sponsor
- University of Aarhus
Proctitis, Ulcerative, Sexually Transmitted Disease (STD)
The Prevalence of Chlamydia Trachomatis and Neisseria Gonorrhoeae in Patients Suspected of Hemorrhagic Proctosigmoiditis
Background Chlamydia trachomatis and Neisseria gonorrhoeae can cause infectious proctitis, which macroscopically cannot be distinguished from haemorrhagic proctosigmoiditis (HP) caused by inflammatory bowel disease.
- Conditions
- Proctitis, Ulcerative, Sexually Transmitted Disease (STD), Ulcerative Proctosigmoiditis
- Trial name
- SOSProctitis (NCT07061899)
- Testing
- Anal swap for Chlamydia and Gonorrhoea
- Where
- 5 sites in Denmark
- Volunteers
- 214 people
- Sponsor
- University of Aarhus
Insomnia Chronic
Determination of Optimal Sleep Treatment Elements - MOST
Previous research has shown the efficacy of (combinations of) individual components of cognitive behavioral therapy for insomnia (CBT-I), namely sleep hygiene education, sleep restriction, stimulus control therapy…
- Trial name
- DOSE (NCT05561829)
- Testing
- Sleep Optimization, Stimulus Control Therapy, Relaxation Training
- Where
- Denmark
- Volunteers
- 489 people
- Sponsor
- University of Aarhus
Cardiac Arrest (CA), Anoxic Brain Injury
Early WAKE-up Predictors After Out-of-Hospital Cardiac Arrest
WAKE-OHCA is a prospective observational substudy of the Danish Out-of-Hospital Cardiac Arrest (DANOHCA) trial, identifier NCT05895838.
- Conditions
- Cardiac Arrest (CA), Anoxic Brain Injury, Comatose Survivors of Cardiac Arrest, EEG
- Trial name
- WAKE-OHCA (NCT06979700)
- Testing
- Automated Pupillometry, Transcranial Doppler Ultrasound, Optic Nerve Sheath Diameter
- Where
- 2 sites in Denmark
- Volunteers
- 250 people
- Sponsor
- University of Aarhus
Hemorrhage, Blood Component Transfusion
Prehospital Transfusion Strategy in Bleeding Patients
The aim of study is to compare clinical and biochemical effect of three different transfusion strategies among patients with major hemorrhage requiring prehospital transfusion.
- Trial name
- NCT04879485
- Testing
- Blood products
- Where
- 2 sites in Denmark
- Volunteers
- 120 people
- Sponsor
- University of Aarhus
Exercise
Community Based Promotion of Physical Activity in Nepal (COBIN-PA)
Globally, one in four adults does not meet the WHO-recommended level of physical activity. Insufficient physical activity is the fourth leading risk factor, contributing to 9% of global premature mortality.
- Trial name
- NCT06386692
- Testing
- FCHVs-led community based educational physical activity intervention
- Where
- Nepal
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Gestational Diabetes Mellitus (GDM)
Insulin Resistance in Gestational Diabetes Mellitus
This prospective cohort study investigates glycaemic variability, assessed by continuous glucose monitoring (CGM), in pregnant women with gestational diabetes mellitus (GDM) and its association with fetal growth and related…
- Trial name
- IRIS (NCT07231341)
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Insomnia, Insomnia Chronic
Sleep Difficulties After Loss: Exploring the Beneficial Effect of Brief Behavioral Therapy for Insomnia in a Sample of Bereaved Individuals
The goal of the study is to investigate whether a brief behavioral therapy for insomnia (BBTI) improves sleep in bereaved patients screened for insomnia compared to an active control group (sleep hygiene education).
- Conditions
- Insomnia, Insomnia Chronic, Complicated Grief
- Trial name
- SLEEPLOSS (NCT07167706)
- Testing
- Brief Behavioral Therapy for Insomnia, Sleep Hygiene Therapy
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- University of Aarhus
Diarrhea, Colitis
FMT in Checkpoint Inhibitor-mediated Diarrhea and Colitis
The goal of this clinical trial is to determine the outcome of patients with immune checkpoint inhibitor-mediated diarrhea/colitis (IMC) treated with faecal microbiota transplantation (FMT) in a randomised, placebo-controlled…
- Conditions
- Diarrhea, Colitis, Malignant Melanoma, Kidney Cancer
- Trial name
- Immunobiome (NCT06206707)
- Testing
- Faecal Microbiota Transplantation (FMT)
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Ileostomy - Stoma, Intestinal Failure
Optimised Osmolality in Oral Supplements Optimised Osmolality in Oral Supplements
Quasi-randomized, crossover intervention study, testing osmolality in oral drinks and effect on 6-hours ileostomy output in adult patients with an ileostomy
- Trial name
- Goldilocks (NCT07231666)
- Testing
- water, semi skimmed milk or powerade, juice
- Where
- 2 sites in Denmark
- Volunteers
- 14 people
- Sponsor
- University of Aarhus
Systemic Lupus Erythematosus (SLE)
European LUpuS Inception-Cohort Developing initiATivE
The goal of this observational study is to learn more about how systemic lupus erythematosus (SLE or lupus) develops in the first years after diagnosis, and how patients respond to different treatments.
- Trial name
- ELUSIDATE (NCT07209540)
- Volunteers
- 700 people
- Sponsor
- University of Aarhus
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