Clinical trials: sponsored by University of Alberta
Child Development, Activity, Motor
Early Movers Pilot Intervention
Our Early Movers longitudinal study found that adherence to the Canadian 24-Hour Movement Guidelines in infancy is low across demographic groups, impacting overall development.
- Trial name
- NCT06538090
- Testing
- Early Movers
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Chronic Low-back Pain
Alberta Rehabilitation Advice Line SelfBack Study
Recurrent and persistent low back pain (LBP) is a massive problem in Canada that causes a substantial pain, disability, cost, and even premature death.
- Trial name
- NCT06484751
- Testing
- SelfBack
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- University of Alberta
Health
The Effect of Dopamine on Pulmonary Diffusion and Capillary Blood Volume During Exercise
The purpose of this study is to examine the effect of dopamine infusion and dopamine-2 receptor blockade on pulmonary capillary blood volume, diffusion, and the hemodynamic variables of pulmonary artery pressure, cardiac output…
- Trial name
- NCT02965963
- Testing
- Dopamine, Metoclopramide, Rest
- Where
- Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Anxiety Depression Disorder
Hemispheric Asymmetries in Emotion-Cognition Interactions
In this research, the investigators will recruit 2 groups of individuals: older adults (aged over 65) with anxiety and/or depression and older adults without mental health issues.
- Trial name
- NCT06406595
- Testing
- Observation
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Recurrent Glioblastoma, Glioblastoma - Category
Role of Repeat Resection in Recurrent Glioblastoma
Patients with recurrent Glioblastoma (GBM) are commonly presented to surgeons, along with the question of whether or not to re-resect the recurrence.
- Trial name
- NCT04838782
- Testing
- Repeat Surgical Management of Recurrent GBM
- Where
- Canada
- Sponsor
- University of Alberta
Type 1 Diabetes
Effects of Resistance Exercise on Blood Glucose in Post-menopausal Women With Type 1 Diabetes
Regular physical activity has substantial health benefits in people with type 1 diabetes. The fear of hypoglycemia, both during and after exercise, is a major barrier to exercise in this population.
- Trial name
- NCT05203640
- Testing
- High repetition (HI), Moderate repetition (MOD)
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Alberta
Major Depressive Disorder, Generalized Anxiety Disorder
Mental Health Assessment and Prescribing by Alberta Pharmacists
This is a clinical trial evaluating the experimental intervention of enhanced pharmacist care by pharmacists with additional prescribing authorization (APA) in Alberta, for patients newly diagnosed with Major Depressive Disorder…
- Conditions
- Major Depressive Disorder, Generalized Anxiety Disorder, Pharmacist-Patient Relations
- Trial name
- MAP-AP (NCT04410575)
- Testing
- Standard Pharmacist Care, Reviewed Questionnaire tool results with participant, Patient Clinical Assessment
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Diabetes type1
cePolyTregs in Islet Transplantation
The transplant of the insulin-producing cell into the liver (Islet transplant) has been proven an effective and valuable treatment for type 1 diabetics patients with poor blood sugar.
- Trial name
- cePolyTregs (NCT05349591)
- Testing
- cePolytreg
- Where
- Canada
- Sponsor
- University of Alberta
Group A Streptococcal Infection
A Trial of a Peptide-based Group A Streptococcal (GAS) Vaccine Candidate in Healthy Individuals.
The purpose of this study is to investigate the safety and antibody (germ fighters) response of experimental (investigational) vaccine candidates against the germ group A streptococcus when injected into the arm of healthy adults.
- Trial name
- NCT04882514
- Testing
- p*17-K4S2, J8-K4S2, Rabavert vaccine
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Common Cold, Pharyngitis
Supporting Parents to Choose Wisely
The goal of this multi-method study including a randomized control trial and qualitative interviews is to see how useful blogshots (an image that summarizes information) are at helping parents increase their knowledge and manage…
- Conditions
- Common Cold, Pharyngitis, Acute Otitis Media, Acute Asthma
- Trial name
- NCT06005337
- Testing
- Blogshots 1-3, Blogshots 4-6
- Where
- Canada
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Type 1 Diabetes Mellitus
Islet Transplantation Using PKX-001
Islet Transplantation is a procedure used in people with difficult to control Type 1 Diabetes. Insulin producing cells (islets) are isolated from a deceased donor pancreas.
- Trial name
- NCT03073577
- Testing
- Antiaging Glycopeptide
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- University of Alberta
Urinary Incontinence
Briefs With Tapes Versus Pull Ups for Urinary Incontinence in Older People With Mild to Moderate Dementia (CUPID)
Urinary incontinence is a common health problem that significantly affects the quality of life of older people. The risk of urinary incontinence is increased in people living with dementia.
- Trial name
- CUPID (NCT04290403)
- Testing
- Pull Ups, Styled Briefs with tapes
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Alberta
ILD
Edmonton Dyspnea Inventory- Validation Study
Breathlessness is a common problem for many patients with Interstitial lung disease (ILD). ILD is a group of lung diseases that cause inflammation (swelling) and scarring in the lung tissue where gas exchange (oxygen and carbon…
- Trial name
- NCT06290635
- Testing
- Breathlessness Assessment Tool
- Where
- 3 sites in Canada, Denmark and 1 more
- Volunteers
- 79 people
- Sponsor
- University of Alberta
Chronic Low-back Pain
Alberta Chiropractic SelfBack Study
Recurrent and persistent low back pain (LBP) is a massive problem in Canada that causes a substantial pain, disability, cost, and even premature death.
- Trial name
- NCT06347991
- Testing
- SelfBack
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Alberta
Syncope
Syncope Trial to Understand Tilt Testing Early or Recorders Study
Pragmatic research study to determine which of the two standard syncope therapies yields a faster path to diagnosis- head up tilt (HUT) table or implantable loop recorder (ILR).
- Trial name
- STUTTER (NCT03974412)
- Testing
- Head Up Tilt Table (HUT), Implantable Loop Recorder
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Metabolic Syndrome, Chronic Obstructive Pulmonary Disease
Digital Metabolic Rehabilitation COPD
People with Chronic Obstructive Pulmonary Disease (COPD) are at greater risk for Metabolic syndrome (MetS). Although the management of MetS will not cure COPD, it can beneficially impact health outcomes and quality of life…
- Trial name
- NCT05806294
- Testing
- Digital Metabolic Rehabilitation
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- University of Alberta
Critical Illness, Acute Kidney Failure
Implementation of CRRT KPI Reports to Standardize and Improve the Quality of CRRT Delivery in Alberta "QUALITY CRRT"
Acute kidney replacement therapy (i.e., dialysis) is used in 6-10% of patients admitted to intensive care units (ICUs). The amount of acute kidney replacement therapy use has increased in Canadian ICUs over the last several…
- Trial name
- QUALITY-CRRT (NCT04221932)
- Testing
- CRRT KPI Reports
- Where
- 14 sites in Canada
- Volunteers
- 945 people
- Sponsor
- University of Alberta
Newborn Infants Having Asystole or Bradycardia at Birth
Chest Compression and Sustained Inflation
Guidelines on neonatal resuscitation recommend 90 chest compressions (CC) and 30 manual inflations (3:1) per minute in newborns.
- Trial name
- NCT02083705
- Testing
- CC+SI, 3:1 CPR
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- University of Alberta
Obesity
Digital Intervention for Behaviour Change and Chronic Disease Prevention
Body weight, diet quality, physical activity, stress, sleep and alcohol use will be evaluated in a sample of 180 Albertans with excess body weight.
- Trial name
- DIRECTION (NCT05579704)
- Testing
- Web-based wellness platform, Healthcare professional-facilitated online support group
- Where
- Canada
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Type 1 Diabetes
Device-Less Technique in Islet Transplantation
Islet transplantation is an effective modality for treating type 1 diabetes. Despite marked progress in clinical islet transplantation with the achievement and maintenance of insulin independence in over half of recipients up to…
- Trial name
- NCT05073302
- Testing
- Implantation of Nylon catheter (Device-less sentinel unit)
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University of Alberta