Clinical trials: sponsored by University of Alberta
Temporomandibular Degenerative Joint Disease
Topical Diclofenac Efficacy in Symptomatic Relief of Temporomandibular Degenerative Joint Disease
The use of a topical medication was compared to placebo to be applied over the symptomatic temporomandibular joint in women with the diagnosis of osteoarthritis of the temporomandibular joint(s).
- Trial name
- NCT00471393
- Testing
- 1.5% diclofenac in 45.5% DMSO (topical treatment)
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Exercise Adherence, Sedentary Adults
Health First-Study 2
The current study was designed to investigate the influence of choice of exercise program on exercise adherence. The two exercise programs included 1) traditional exercise at a fitness centre or 2) lifestyle exercise-walking…
- Conditions
- Exercise Adherence, Sedentary Adults, Lifestyle, Traditional
- Trial name
- NCT00281437
- Testing
- choice of exercise program
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Malocclusion, Angle Class III
Periodontal Ligament Stress Level and Tooth Movement
Orthodontic treatment requires application of force systems to individual teeth or groups of teeth, which results in a cellular response with periodontal ligament (PDL) and alveolar bone remodeling.
- Trial name
- NCT00099814
- Testing
- Two different loop designs which deliver distinctive forces
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Head and Neck Neoplasms
Resistance Exercise Training for the Shoulder and Neck Following Surgery for Head and Neck Cancer
The purpose of this study is to investigate the effect of a progressive therapeutic exercise program on specific physical and functional deficits in the neck and shoulder region occurring as a result of head and neck cancer…
- Trial name
- NCT00248235
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of Alberta
Breast Cancer
Physical Activity Promotion in Breast Cancer Survivors
Over 30 studies have shown that exercise can improve physical fitness, reduce fatigue, increase functioning, and enhance overall quality of life (QoL) in breast cancer survivors both during and after treatments.
- Trial name
- NCT00221221
- Testing
- Pedometer, Exercise guidebook
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- University of Alberta
Sedentary Behaviour, Adherence
Health and Psychological Outcomes of Lifestyle Versus Traditional Physical Activity
This study is a comparison of the traditional prescription versus the lifestyle exercise prescription in sedentary adults over 6 months. Biological and psychological parameters will be assessed over the 6 month study.
- Conditions
- Sedentary Behaviour, Adherence, Traditional Exercise, Lifestyle Exercise
- Trial name
- NCT00281385
- Testing
- traditional vs. lifestyle exercise
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Malocclusion, Angle Class II
Crossbow Versus Forsus Springs in Mild to Moderate Class II Malocclusion Cases
Class II malocclusion (mismatch between the upper and lower jaw in which the lower jaw appears to be smaller from a profile point of view) are common in the general population.
- Trial name
- NCT01530516
- Testing
- Brackets plus Forsus springs, Xbow plus full brackets
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- University of Alberta
Diabetes
Home Based Resistance Training For Type 2 Diabetes
This study will investigate the biological and psychosocial benefits of a home-based resistance-training program for sedentary, obese adults living with type 2 diabetes.
- Trial name
- NCT00221208
- Testing
- Resistance Training
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Type 2 Diabetes
Alberta Diabetes and Physical Activity Trial
This project will assess the incremental and cumulative impact of three behavioural intervention strategies for the promotion of physical activity in the adult general population with Type 2 diabetes.
- Trial name
- NCT00221234
- Testing
- Print materials, pedometers/logbooks, Print materials, pedometers/logbooks, telephone counselling
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Pulmonary Hypertension, COPD
Integrating ePReBMs From Phoenix in Respiratory Diseases
Participants with respiratory disease experience often a worsening of their condition, with increasing symptoms such as cough and shortness of breath.
- Conditions
- Pulmonary Hypertension, COPD, Interstitial Lung Disease, Healthy Volunteers
- Trial name
- NCT05827302
- Testing
- Health Gauge AI-Based Wearable Device - Model: Phoenix
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Non-alcoholic Fatty Liver Disease
Fructose and Liver Diseases in Youth: Help Them FLY
Obesity has been increasing all over the world. This has lead to a significant increase of a liver disease in children called non-alcoholic fatty liver disease (NAFLD).
- Trial name
- FLY (NCT05528471)
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University of Alberta
Lower Urinary Tract Symptoms
Management of LUTS by Community Pharmacists
Many older adults have urinary incontinence. They often seek treatments, such as diapers, pads, or medications, from the community pharmacy.
- Trial name
- NCT04331340
- Testing
- Pharmacist review of LUTS, Pharmacist Provision of healthy aging leaflets
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Multiple Sclerosis, Nurse's Role
The Effect of Nurse Practitioner (NP-led) Care Upon Mood in People With Multiple Sclerosis
MS is the leading cause of non-traumatic disability in young adults. Canada and Alberta, have the highest prevalence of people with multiple sclerosis (PwMS) in the world.
- Trial name
- NCT04388592
- Testing
- Nurse Practitioner (NP) Led Care Arm
- Where
- Canada
- Volunteers
- 248 people
- Sponsor
- University of Alberta
Spasticity, Muscle, Spinal Cord Injuries
Effects of Baclofen on Presynaptic Inhibition in Humans
This study examines the role of the GABA-B receptor in long-lasting presynaptic inhibition of primary afferents in human participants.
- Trial name
- NCT04471714
- Testing
- Baclofen
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta
Multiple Sclerosis
Reducing Sedentary Behaviour: A Novel Opportunity for Managing Comorbidity in MS?
Activity recommendations for the general population and those with multiple sclerosis (MS) focus on the promotion of activity that has a moderate intensity - in other words, activity intense enough to breathe heavily and sweat.
- Trial name
- NCT03136744
- Testing
- Sit Less with MS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Hypercholesterolemia
Kefir Cholesterol Lowering Pilot Study
High cholesterol (a type of fat in humans blood) may be one factor that can lead to heart disease. If people have higher cholesterol, it is possible that kefir (a food similar to yogurt) may help to control blood cholesterol…
- Trial name
- NCT04247139
- Testing
- Kefir
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Stroke (CVA) or TIA, Headache, Migraine
Onabotulinum Toxin A (Botox) for the Treatment of Persistent Post-Stroke and Vascular Headache
Post stroke headache occurs in approximately 10-23% of all stroke patients. Its onset is shortly after experiencing a stroke, or stroke like event, and persists for at least three months.
- Conditions
- Stroke (CVA) or TIA, Headache, Migraine, Botulinum Toxins, Type A, Cerebral Venous Sinus Thrombosis
- Trial name
- NCT04580238
- Testing
- Botox 200 UNT Injection, Non Botox based Standard of Care Treatments for Headache/Migraine
- Where
- Canada
- Sponsor
- University of Alberta
Aphasia
Voice Adaptive Tablet-Based Naming Treatment for Adults With Aphasia
Rising life expectancy is leading to a rising incidence of strokes worldwide. Approximately one third of people who had a stroke live with a communication disorder, aphasia, which is associated with the largest negative…
- Trial name
- VoiceAdapt (NCT04108364)
- Testing
- Voice adaptive training for aphasia
- Where
- 2 sites in Canada
- Volunteers
- 38 people
- Sponsor
- University of Alberta
Pancreatic Cancer
A Study to See Whether a Nutritional Supplement is Beneficial for Patients With Pancreatic Cancer
This study evaluates a nutritional supplement in the treatment of pancreatic cancer in adults. Half of the participants will receive the nutritional supplement, while the other half will receive a placebo.
- Trial name
- NCT02745197
- Testing
- Nutritional Supplement
- Sponsor
- University of Alberta
Musculoskeletal Injury
Non-Steroidal or Opioid Analgesia Use for Children With Musculoskeletal Injuries
Musculoskeletal (MSK) injuries, including limb injuries, are the most common cause for Emergency Department (ED) visits for children with pain.
- Trial name
- No OUCH (NCT03767933)
- Testing
- Ibuprofen, Acetaminophen, Hydromorphone
- Where
- 6 sites in Canada
- Volunteers
- 710 people
- Sponsor
- University of Alberta