Clinical trials: sponsored by University of Alberta
Heart Defects
Physical Activity Measured Through Accelerometers and Its Association With Endothelial Function in Young Patients With Fontan Physiology
This study will be a cross sectional assessment of physical activity as measured through accelerometers and its association with endothelial function of children with Fontan circulation and healthy age and gender matched controls…
- Trial name
- NCT02938429
- Testing
- Physical activity measures via Actigraph GT3X+ accelerometers for 7 consecutive days
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of Alberta
Hepatic Encephalopathy
Fecal Transplant for Hepatic Encephalopathy
The purpose of the study is to determine if fecal microbiota transplant (FMT) can reverse hepatic encephalopathy (HE) in cirrhotic patients who continue to have breakthrough episodes of HE despite maintenance therapy with…
- Trial name
- NCT03439982
- Testing
- FMT
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University of Alberta
Head and Neck Squamous Cell Carcinoma
2B or Not 2B? Shoulder Function After Level 2B Neck Dissection: A Randomized Controlled Study
Many types of head and neck cancers will have local spread to the neck. As such selective neck dissection is performed as part of the treatment. The neck is divided into various levels.
- Trial name
- 2BN2B (NCT00765791)
- Testing
- Selective Neck Dissection Excluding Level 2B, Selective Neck Dissection Including Level 2B
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Heart Failure
Study of Dietary Intervention Under 100 MMOL in Heart Failure
This study aims to identify the relationship between a low-sodium diet and neurohormonal and clinical status in stable chronic HF patients.
- Trial name
- SODIUM-HF (NCT01480401)
- Testing
- low-sodium diet (1500 mg daily)
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- University of Alberta
Diabetic Foot Ulcer
Diabetes Foot Care Clinical Pathway - Orpyx Medical Technologies
In 2011, the premiers of all Canadian provinces and territories selected diabetes foot care as one of three significant targets for pan-provincial action.
- Trial name
- DFCCP-Orpyx (NCT02994966)
- Testing
- Surrosense, Standard care
- Where
- 3 sites in Canada
- Volunteers
- 120 people
- Sponsor
- University of Alberta
Influenza Infection in Transplant Patients
Influenza Virus - A Multicenter Registry
The investigators purpose is to prospectively characterize influenza infections over a 3 year period in transplant patients using a registry system.
- Trial name
- NCT01256255
- Where
- 2 sites in Canada
- Volunteers
- 282 people
- Sponsor
- University of Alberta
Transplant
Cytomegalovirus (CMV) MicroRNA Expression in Vivo and Immune Evasion Correlates
Cytomegalovirus (CMV) is the most common viral infection in patients who have undergone a transplant.Serious infections due to CMV can affect many parts of the body including the lungs, the gut, and the liver.
- Trial name
- NCT00677482
- Where
- Canada
- Volunteers
- 47 people
- Sponsor
- University of Alberta
Kidney Transplant
Safety and Immunogenicity of Zostavax Vaccine in Patients Undergoing Living Donor Kidney Transplantation
Varicella zoster virus is part of the herpesvirus group and causes chickenpox in exposed individuals. The majority of the population is seropositive for this virus.
- Trial name
- NCT00940940
- Testing
- Zostavax (Live attenuated herpes zoster vaccine)
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- University of Alberta
Sacroiliac Joint Somatic Dysfunction
Fluoroscopic vs Ultrasound Guided Sacroiliac (SI) Joint Radiofrequency Ablation
The sacroiliac joint (SIJ) is estimated to be the source of low mechanical back pain in 10-27% of patients. When conservative measures for treating SIJ pain fail (physiotherapy, exercise, analgesic medications, chiropractic…
- Trial name
- NCT04534829
- Testing
- Fluoroscopic-guided Radiofrequency Ablation, Ultrasound-guided Radiofrequency Ablation
- Where
- Canada
- Sponsor
- University of Alberta
Pediatric Obesity, Motivational Interviewing
Motivation to Change Lifestyle Habits in Youth With Obesity
Approximately one-third of Canadian children have excess weight, putting them at increased risk of type 2 diabetes, cardiovascular disease, bone and joint problems, and some forms of cancer.
- Trial name
- RMI-Family (NCT03527394)
- Where
- 2 sites in Canada
- Volunteers
- 54 people
- Sponsor
- University of Alberta
Scoliosis
Multicenter Schroth Exercise Trial for Scoliosis
The primary aim of this multicenter randomized controlled trial is to compare the effect of a 6 month "Schroth exercise program combined with standard-of-care" to "standard-of-care alone" on scoliosis curve severity measured…
- Trial name
- MultiSETS (NCT01610908)
- Testing
- The Schroth exercises treatment, Global Postural Re-Education
- Where
- 3 sites in Canada
- Volunteers
- 158 people
- Sponsor
- University of Alberta
Ischemic Stroke
Asia Africa Streptokinase Trial
Currently, thrombolysis is offered to less than 1% of patients in low to middle income countries (LMICs) where access to health care is often based on the financial capabilities of the patient.
- Trial name
- AASIST (NCT02150785)
- Testing
- Streptokinase
- Sponsor
- University of Alberta
Quality of Life
Patient-Centred Care for Warfarin Management: A Pilot Study to Transition Care to High Risk Patients
Warfarin remains the only oral anticoagulant effective in preventing stroke and valve thrombi for patients having mechanical heart valves (MHVs).
- Trial name
- NCT03295799
- Testing
- Patient Self-Management
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- University of Alberta
Bowel Disease, Liver Diseases
The Impact of an Epidural Anesthetic on the Consumption of Sevoflurane in Major Abdominal Surgery
Major abdominal surgery - like non-laparoscopic bowel resection, liver, gastric, or pancreas surgery - is performed under general anesthesia.
- Conditions
- Bowel Disease, Liver Diseases, Pancreas Disease, Anesthesia; Functional
- Trial name
- NCT04021264
- Testing
- Ropivacaine-Sufentanil, Dextrose 5
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta
Cirrhosis
Effects of Aerobic Training on Exercise Capacity in Patients With Advanced Cirrhosis 2
Cirrhosis is associated with a reduction in muscle mass and exercise capacity. This has an impact on morbidity and mortality. Regular aerobic exercise training is a proven effective therapy to improve exercise capacity in healthy…
- Trial name
- NCT01960127
- Testing
- Aerobic Exercise, No Intervention
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Alberta
Transient Ischemic Attacks, Minor Stroke
The Middle East Dual Anti-platelet Treatment in Acute Transient Ischemic Attack
The primary goal of the research is to determine if 10 days of dual anti-platelet treatment is as effective as 30 days of similar treatment in the prevention of stroke, myocardial ischemia (MI) and death in patients with TIAs and…
- Trial name
- MENA-TIA (NCT02144831)
- Testing
- anti-thrombotic treatment using Aspirin (ASA 75-325mg) and Clopidogrel (75mg)
- Where
- Canada
- Sponsor
- University of Alberta
Rectal Cancer
Exercise During and After Neoadjuvant Rectal Cancer Treatment
This study is designed to investigate if aerobic exercise during and after neoadjuvant chemoradiotherapy (NACRT) can improve outcomes for rectal cancer patients.
- Trial name
- EXERT (NCT03082495)
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University of Alberta
Urinary Incontinence, Stress
Hip External Rotation Physical Therapy Trial
This RCT is a feasibility study to evaluate the Lois Hole Hospital for Women's Urogynecology Clinic's ability to recruit and randomize SUI patients to the proposed RCT, and to test the study procedures and follow-up schedule for…
- Trial name
- HER-Physio (NCT03296462)
- Testing
- Hip external rotation exercise, Pelvic floor muscle exercise
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- University of Alberta
Vasodilation, Vasoconstriction
The Impact of Carbon Monoxide and Altitude on Vascular Function
The CarMA (Carbon Monoxide and Altitude) Study aims to observe the vascular effects of carbon monoxide exposure at low and high altitudes.
- Trial name
- CarMA (NCT04928183)
- Testing
- Carbon monoxide rebreathe, Sodium Nitroprusside, Phenylephrine Hydrochloride
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Rotator Cuff Injury, Anesthesia; Functional
The Impact of a Preoperative Nerve Block on the Consumption of Sevoflurane
Arthroscopic rotator cuff surgery of the shoulder is performed under general anesthesia. Pain control for after the surgery can be achieved purely with intravenous and oral pain medication or in combination with freezing of the…
- Trial name
- NCT03533452
- Testing
- Ropivacaine, Normal saline
- Where
- 2 sites in Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Alberta