Clinical trials: sponsored by University of Alberta
Cirrhosis
Effects of Home Based Exercise Therapy in Early Cirrhosis
Individuals with Cirrhosis have been shown to have a low aerobic capacity. While supervised exercise training has been shown to be an effective intervention to remedy this, there is currently no data on home based exercise…
- Trial name
- NCT02267421
- Testing
- Home based Aerobic exercise training
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Chronic Obstructive Pulmonary Disease (COPD)
The CaNadian Standardized Pulmonary Rehabilitation Efficacy Trial
Chronic obstructive pulmonary disease (COPD) is a chronic lung disease primarily caused by smoking. Pulmonary rehabilitation (PR) is an evidence-based, interdisciplinary, and comprehensive intervention for COPD patients that…
- Trial name
- CoNSPiRE (NCT02917915)
- Testing
- Canadian Standardized PR, Traditional PR
- Where
- Canada
- Volunteers
- 207 people
- Sponsor
- University of Alberta
Stress, Psychological, Mind Body Therapy
Online Wellness Intervention in Medical Students
Medical students are at high risk of stress. This project will test how well a 12-week stress reduction program works to reduce stress, anxiety and depression and improve well-being.
- Conditions
- Stress, Psychological, Mind Body Therapy, Wellbeing
- Trial name
- NCT04612387
- Testing
- Mind-body therapy
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- University of Alberta
Children Requiring IV Placement
Virtual Reality-based Distraction to Reduce Distress in the Pediatric Emergency Department
Needle procedures, such as intravenous (IV) insertions, are among the most commonly performed procedures for children needing medical care.
- Trial name
- NCT04291404
- Testing
- Virtual Reality Distraction
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- University of Alberta
Fluid Overload, Vascular Stiffness
Target Weight Correction and Vascular Stiffness in Hemodialysis Patients
Title of the study: Target weight correction and vascular stiffness in hemodialysis patients Study design: Randomized clinical trial in the study centre at two locations Applied medical device: 1.
- Trial name
- NCT03929471
- Testing
- Target weight correction protocol
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Alberta
Pneumonia, Hypoxemia
Solar Oxygen Study
Globally, approximately 7.7 million children per year die before the age of 5 years. Infectious diseases account for a large proportion of these deaths, with pneumonia being the leading cause of mortality (2.1 million…
- Trial name
- SOS (NCT03851783)
- Testing
- Solar-powered oxygen
- Where
- 20 sites in Uganda
- Volunteers
- 2,405 people
- Sponsor
- University of Alberta
Congenital Hyperinsulinism, Neuroblastoma
18F-DOPA PET Imaging: an Evaluation of Biodistribution and Safety
Single centre prospective cohort phase III study of 18F-DOPA PET/CT imaging in specific patient populations: 1. Pediatric patients with congenital hyperinsulinism 2. Pediatric patients with neuroblastoma 3.
- Conditions
- Congenital Hyperinsulinism, Neuroblastoma, Neuroendocrine Tumors, Parkinson Disease
- Trial name
- NCT03042416
- Testing
- 18F-DOPA
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- University of Alberta
Obesity, Metabolic Syndrome
Fecal Microbial Transplantation and Fiber Supplementation in Participants With Obesity and Metabolic Syndrome.
Obesity is increasing in western society at a rapid rate and is associated with metabolic and cardiovascular disease. Although genetics, improper diet, and sedentary lifestyle are known to be factors that can cause obesity, there…
- Trial name
- NCT03477916
- Testing
- FMT, Prebiotic Fiber, Cellulose
- Where
- Canada
- Volunteers
- 68 people
- Sponsor
- University of Alberta
Attention Deficit/Hyperactivity Disorder, Initial Insomnia
Melatonin in Youth: N-of-1 Trials in a Stimulant-treated Attention Deficit Hyperactivity Disorder (ADHD) Population
This study is a multi-center, randomized, triple-blind, placebo-controlled parallel-group trial, in which each participant is offered an N-of-1 trial.
- Trial name
- MYNAP (NCT02333149)
- Testing
- Melatonin
- Where
- Canada
- Sponsor
- University of Alberta
Full Thickness Rotator Cuff Tears
Early Mobilization Following Mini-Open Rotator Cuff Repair
The primary objective of this study is to determine if early active range of motion after mini-open rotator cuff repair in adults results in improved shoulder range of motion at 6 weeks and 3 months after surgery.
- Trial name
- NCT01741272
- Testing
- Sling, No sling
- Where
- Canada
- Volunteers
- 189 people
- Sponsor
- University of Alberta
Rotator Cuff Tear
Early Mobilization Following Arthroscopic Rotator Cuff Repair
Shoulder rotator cuff (RC) tears are a significant cause of pain and disability. Surgery is done to reconnect the torn RC tendon(s) to the bone.
- Trial name
- NCT01333527
- Testing
- No Sling, Sling
- Where
- Canada
- Volunteers
- 211 people
- Sponsor
- University of Alberta
Spinal Cord Injury
Restoring Walking With a Powered Exoskeleton After Spinal Cord Injury
Powered exoskeletons have emerged recently, promising to offer walking to individuals with severe spinal cord injury who are unable to walk.
- Trial name
- NCT02322125
- Testing
- ReWalk
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Alberta
Kidney Disease, End-Stage
Electronic Patient-Reported Outcomes in Clinical Kidney Practice (ePRO Kidney)
People living with end-stage kidney disease (ESKD) need dialysis or transplantation in order to stay alive. This illness and treatment significantly impact peoples' health, emotions, work and relationships.
- Trial name
- NCT03149328
- Testing
- Educational Support
- Where
- 2 sites in Canada
- Volunteers
- 594 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Hepatic Encephalopathy
Fecal Microbiota Transplantation (FMT) in the Management of Hepatic Encephalopathy (HE): a Pilot Study
The purpose of this study is to determine if FMT can reverse Hepatic Encephlopathy (HE) in cirrhotic patients who continue to have breakthrough episodes of HE despite maintenance therapy with lactulose and/or rifaximin or…
- Trial name
- NCT02255617
- Testing
- Fecal Microbiota Transplant
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- University of Alberta
Athlete's Shoulder
Effectiveness of an 8-week Posterior Shoulder Stretching Program on Varsity-level Overhead Athletes
To Determine whether an eight-week posterior shoulder stretch was effective in increasing dominant arm internal rotation(IR) and horizontal adduction (HAd) range of motion (ROM) in a group of overhead athletes identified as…
- Trial name
- NCT01749553
- Testing
- Sleeper Stretch
- Where
- Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Alberta
SLAP Lesion
BicepsTenodesis vs. Biceps Debridement in Combined RC Tears and SLAP Lesions
The appropriate treatment of labral lesions such as SLAP tears in patients undergoing RC tears repair is controversial. Most surgeons are reluctant to repair RC and SLAP tears simultaneously due to the high likelihood of…
- Trial name
- NCT03189147
- Testing
- Biceps Tenodesis, Debridement
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Radius Fracture
Distal Radial Fractures in the Late Middle Aged
Background: Wrist fractures are a common injury among people aged 55-70. The radius is one of the bones making up the wrist joint, and is typically the site of injury in a broken wrist.
- Trial name
- RIST (NCT02353338)
- Testing
- Surgical intervention, Conservative management, cast
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Multiple Myeloma
Virtual Exercise for Multiple Myeloma
The primary objective of this pilot study is to determine the safety and feasibility a 12-week virtually supported home-based aerobic and resistance exercise program progressing cancer survivors with Multiple Myeloma to meet…
- Trial name
- MY-PROGRESS (NCT04484714)
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- University of Alberta
Chronic Obstructive Pulmonary Disease (COPD)
Examining Vascular Outcomes in COPD Inpatients (AIM 1) Examining Early Rehabilitation on Discharged COPD Patients (AIM 2)
Chronic obstructive pulmonary disease (COPD) is a chronic lung disease primarily caused by smoking. COPD creates a tremendous burden to the healthcare system, as disease exacerbations result in frequent, prolonged…
- Trial name
- NCT01949727
- Testing
- AIM 2: Pulmonary Rehabilitation
- Where
- Canada
- Volunteers
- 111 people
- Sponsor
- University of Alberta
Premature Infant, Respiratory Distress Syndrome
The Hilo Pilot -Trial to Assess Feasibility
Preterm birth, or birth before 37 weeks' gestation, is increasingly common, occurring in 8% of pregnancies in Canada. Preterm birth is associated with many health complications, particularly when the birth happens before 29…
- Trial name
- HiLo-Pilot (NCT03706586)
- Testing
- 30% group, 60% group
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- University of Alberta