Clinical trials: sponsored by University of Alberta
Probable Migraine, Migraine With Aura
Intravenous Ketorolac and Metoclopramide for Pediatric Migraine in the Emergency Department
Migraine headaches are a common problem for children. When treatment at home fails, children may benefit from intravenous treatment administered in a hospital setting like the Emergency Department.
- Conditions
- Probable Migraine, Migraine With Aura, Migraine Without Aura
- Trial name
- EDMigraine-4 (NCT01596166)
- Testing
- Ketorolac Tromethamine, Metoclopramide
- Where
- 2 sites in Canada
- Volunteers
- 56 people
- Sponsor
- University of Alberta
Pyelonephritis
Antibiotic Prophylaxis in Children With Pyelonephritis
Children who present with pyelonephritis undergo many investigations, and long term care to prevent renal damage. The focus is primarily on preventing renal failure however along the way and particularly with children, other…
- Trial name
- NCT00752375
- Testing
- Trimethoprim Sulfamethoxazole
- Where
- Canada
- Sponsor
- University of Alberta
Dementia
Pilot Study of the Living With Hope Program for Family Caregivers of Persons With Dementia Residing in Long Term Care
Hope is important for family/friends of persons with dementia residing in Long Term Care Facilities. Our research team has developed a program (Living with Hope) to increase hope and quality of life of family caregivers.
- Trial name
- NCT02038192
- Testing
- Living with Hope Program, Stories of the Present
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University of Alberta
Influenza
Adjuvanted Influenza Vaccine Evaluation in Kidney Transplant Recipients
Influenza is an important public health problem. Organ transplant patients are particularly susceptible to severe disease. Also, they shed higher quantities of virus for longer durations, leading to greater contagious potential…
- Trial name
- NCT01584908
- Where
- Canada
- Volunteers
- 68 people
- Sponsor
- University of Alberta
Transplant
Safety and Immunogenicity of Human Papillomavirus (HPV) Vaccine in Solid Organ Transplant Recipients
Human papillomavirus (HPV) affects a significant number of transplant patients. In women, human papillomavirus (HPV) causes genital warts, pre-cancerous areas of the cervix, and cervical cancer.
- Trial name
- NCT00677677
- Testing
- Human papillomavirus quadrivalent vaccine
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Parental Anxiety, Children's Safety
Randomised Controlled Trial to Investigate the Effect of Parental Presence at Intensive Care Unit to Ward Transfer Bedside Rounds on Parental Anxiety and Children's Safety
The investigators shall conduct a randomized controlled trial to investigate the effect of parental presence at transfer rounds on parental anxiety and patient safety following transfer from the Pediatric Cardiac Intensive Care…
- Trial name
- NCT01883739
- Testing
- Parental Presence at Handover Rounds
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Coronary Artery Disease
In-human Validation of a Technique for Measuring Central Aortic Hemodynamics With Peripheral Arterial Waveforms
Central aortic blood pressure (BP) and flow are generally more informative about the health condition of the heart and the arterial system compared with BP measured in peripheral locations (e.g. arm or leg).
- Trial name
- NCT01567748
- Testing
- BP Measurements at aorta, radial and femoral locations
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Quality of Life
Pilot Study of Living With Hope Program
Hope is important to palliative home care patients. Our research team has developed a Living with Hope Program that has been found to increase hope and quality of life in older persons with advanced cancer.
- Trial name
- NCT01697982
- Testing
- Living with Hope Program, LWH film
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- University of Alberta
Multinodular Goitre, Grave's Disease
A Prospective Randomized Equivalence Trial to Evaluate the Safety of the Ligasure in Thyroid Surgery
This is a randomized, prospective equivalence trial on the safety of the Ligasure Vessel Sealing System as used in thyroid surgery.
- Conditions
- Multinodular Goitre, Grave's Disease, Thyroid Nodule
- Trial name
- NCT01163565
- Testing
- Ligasure Device
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University of Alberta
Transient Ischemic Attack, Minor Ischemic Stroke
Dabigatran Treatment Following Transient Ischemic Attack and Minor Stroke
Objective: Demonstrate the safety of early use of dabigatran following TIA/minor stroke. Background: Although aggressive antithrombotic therapy has been shown to reduce the number of new ischemic events following stroke/TIA, this…
- Trial name
- DATAS (NCT01769703)
- Testing
- Dabigatran 110/150 mg BID
- Where
- Canada
- Volunteers
- 53 people
- Sponsor
- University of Alberta
Choroideremia
The Short-term Effects of Simvastatin on the Vision of Males Affected by Choroideremia
Primary objective: To examine the short-term effects of of simvastatin on the vision on males with choroideremia, evaluated by full-field scotopic threshold testing.
- Trial name
- NCT01654562
- Testing
- Simvastatin
- Where
- Canada
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Malignant Gliomas, Glioblastoma Multiforme
The Safety and Efficacy of DCA for the Treatment of Brain Cancer
Malignant gliomas, which include Glioblastoma multiforme (GBM), are the most common and most aggressive types of brain cancer, accounting for approximately 60% of primary brain tumors.
- Trial name
- NCT00540176
- Testing
- Dichloroacetate (DCA)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Pulmonary Hypertension (Idiopathic, Familial or Anorexigen-associated)
Dichloroacetate (DCA) for the Treatment of Pulmonary Arterial Hypertension
Hypothesis: The small molecule and metabolic modulator Dichloroacetate (DCA) is safe, tolerated as a potential therapy in patients with moderate or severe Pulmonary Arterial Hypertension (PAH).
- Trial name
- NCT01083524
- Testing
- Dichloroacetate Sodium
- Where
- 2 sites in Canada, United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Alberta
Type 1 Diabetes, Pregnancy
Pancreatic Islet Mass in Pregnancy in Type 1 Diabetes
Type 1 diabetic women have a decrease in insulin requirements during early pregnancy. Preliminary evidence suggests this decrease may be secondary to the regeneration of pancreatic B-cells during pregnancy During the second and…
- Trial name
- NCT00548522
- Where
- 2 sites in Canada
- Volunteers
- 12 people
- Sponsor
- University of Alberta
Focus: Nutritional Requirements for Infants
Assessment of Arachidonic Acid Supplementation in Infant Formula on the Immune Response of Infants
The immune system of newborn infants is immature with low activity of both innate and acquired immune reactions. Early nutrition has an impact on early immune responses.
- Trial name
- NCT02092857
- Testing
- Arachidonic acid (25 mg/100 kcal ), Arachidonic acid (34 mg/100 kcal)
- Where
- Canada
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Dupuytren Contracture
Collagenase and Needle Aponeurotomy: Single Modality Versus Combination Treatment for Dupuytren's Disease
Dupuytren's disease results in deformity of the hand and this can lead to trouble with daily activities. Treatment traditionally involves cutting out diseased tissue, however this can cause damage to important structures in the…
- Trial name
- NCT01776892
- Testing
- Collegenase injection, Needle aponeurotomy
- Where
- Canada
- Sponsor
- University of Alberta
Obesity, Child
The PAC Study: Parents as Agents of Change in Pediatric Weight Management
The Canadian pediatric obesity epidemic has led to great interest in evaluating weight management care for obese children and families.
- Trial name
- PAC (NCT01267097)
- Testing
- Cognitive Behavioural Therapy (CBT), Psycho-Education Program (PEP)
- Where
- Canada
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Nutrition Assessment, Obesity
Efficacy of Portion Size Measurement Aids
Portion size measurement aids (PSMAs) are tools that facilitate the estimation of food servings. The objectives of this study are to determine (a) if food portion size estimation accuracy differs when using a two dimensional (2D)…
- Trial name
- PSMA (NCT01262768)
- Testing
- Portion Size Measurement Aids (PSMAs)
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Burn, Hypertrophic Scar
Intron A for the Treatment of Hypertrophic Scar
This study assesses the intervention with antifibrotic agents, specifically interferon (IFN) to reduce the magnitude and duration of hypertrophic scar.
- Trial name
- NCT00686478
- Testing
- interferon alpha 2b
- Where
- Canada
- Sponsor
- University of Alberta
Mental Health Wellness 1
Mindfulness-based Stress Reduction for Pediatric Mental Health
Mindfulness-based stress reduction (MBSR) is a group program in which participants are taught to be mindful or present-focused. MBSR programs consist of instruction in a variety of mindfulness meditations including body scan…
- Trial name
- MBSR (NCT01307943)
- Testing
- Mindfulness-based stress reduction program, Usual care
- Where
- Canada
- Volunteers
- 85 people
- Sponsor
- University of Alberta