Clinical trials: sponsored by University of Alberta
Warfarin
Does Anticoagulant Control Change Following Referral Back to the Primary Care Physician?
Warfarin is a medication typically referred to as a blood thinner and is used to prevent the formation of blood clots, and hence prevent life-threatening events such as strokes and clots on the lungs (known as pulmonary emboli).
- Trial name
- NCT00735189
- Testing
- anticoagulation clinic care, usual care
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University of Alberta
Jaundice, Neonatal
Transcutaneous Bilirubinometers in the Community
Jaundice is the most frequent reason for readmission for healthy newborns after discharge from the nursery. In the Capital Health area, around 2.5% (315 babies in 2005) of all healthy newborns were admitted to the hospital for…
- Trial name
- TcB RCT (NCT00735319)
- Testing
- Transcutaneous Bilirubinometer
- Where
- 6 sites in Canada
- Volunteers
- 10,000 people
- Sponsor
- University of Alberta
Type 1 Diabetes
Islet Transplantation Using Campath-1H and Infliximab Induction
Islet transplantation has been investigated as a treatment for Type 1 diabetes mellitus in selected patients with inadequate glucose control despite insulin therapy.
- Trial name
- NCT00175266
- Testing
- alemtuzumab, islet transplant, infliximab
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Alberta
Immunosuppression, Hyperlipidemias
Cholesterol and Fatty Acid Synthesis in Islet and Liver Transplant Patients and Effect of Dietary Intervention
The purpose is to investigate possible mechanisms of increased blood lipid levels following transplantation, and also to see if a comprehensive dietary intervention is effective in reducing blood lipid levels in post-transplant…
- Conditions
- Immunosuppression, Hyperlipidemias, Diabetes Mellitus, Type 1
- Trial name
- NCT00947635
- Testing
- Dietary intervention - supplements
- Where
- Canada
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Portal Vein Thrombosis, Splenic Vein Thrombosis
Anticoagulation Post Laparoscopic Splenectomy
Splenic/portal vein thrombosis is an alarming complication of splenectomy. Retrospective studies in the literature have shown the incidence of symptomatic splenic/portal vein thrombosis to be between 0.7% (Rattner et al., 1993)…
- Trial name
- NCT00769873
- Testing
- Enoxaparin
- Where
- 2 sites in Canada
- Volunteers
- 35 people
- Sponsor
- University of Alberta
Sedation
A Trial Comparing Propofol to Midazolam Plus Meperidine Sedation for Outpatient Colonoscopy
-to determine if propofol sedation leads to shorter recovery times compared to traditional sedation using midazolam plus meperidine
- Trial name
- NCT00848861
- Testing
- propofol (sedation for outpatient colonoscopy), midazolam plus meperidine (sedation for outpatient colonoscopy)
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- University of Alberta
Acute Illness
Triage Liaison Physician - Evaluation of a Novel Approach to Address Emergency Department Overcrowding
This randomized controlled trial will introduce a triage liaison physician (TLP) into the University of Alberta Hospital Emergency Department (ED) and assess the influence on patients who leave without being seen, ED length of…
- Trial name
- NCT00435890
- Testing
- Triage Liaison Physician
- Where
- Canada
- Volunteers
- 5,718 people
- Sponsor
- University of Alberta
Acute Illness
Clinical Decision Unit (CDU) - Evaluation of a Novel Approach to Address Emergency Department Overcrowding
This randomized controlled trial will introduce a Clinical Decision Unit (CDU) into the University of Alberta Hospital Emergency Department(ED)and assess the influence on ED length of stay, patients who leave without being seen…
- Trial name
- NCT00497393
- Testing
- Clinical Decision Unit
- Where
- Canada
- Volunteers
- 6,217 people
- Sponsor
- University of Alberta
Kidney Failure, Acute
Evaluation of a Simplified Protocol for Regional Citrate Anticoagulation in Continuous Venovenous Hemodiafiltration
Dialysis requires thinning of the blood to prevent clotting in the dialysis machine. Thinning of the blood is necessary but some forms of blood thinners may cause bleeding.
- Trial name
- NCT00583765
- Testing
- Regional citrate anticoagulation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Crohn's Disease, Inflammatory Bowel Disease
A Randomized Controlled Trial of VSL#3 for the Prevention of Endoscopic Recurrence Following Surgery for Crohn's Disease.
This randomized placebo-controlled double-blind, multi-centre trial will determine the efficacy of the probiotic VSL#3 in the prevention of Crohn's disease development following surgical resection and re-anastomosis.
- Trial name
- NCT00175292
- Testing
- Probiotic - VSL#3
- Where
- 17 sites in Canada
- Volunteers
- 120 people
- Sponsor
- University of Alberta
Diabetes Mellitus, Type 2, Heart Failure, Congestive
Patients With Heart Failure ANd Type 2 Diabetes Treated With Placebo Or Metformin (PHANTOM) Pilot Study
To conduct a pilot study to evaluate the feasibility of a large randomized controlled trial (RCT) of metformin in patients with heart failure and type 2 diabetes and to generate initial morbidity and mortality estimates in this…
- Trial name
- NCT00325910
- Testing
- Metformin
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University of Alberta
Hypertension, Diabetes Mellitus, Type 1
Improving Blood Pressure Management in Patients With Diabetes
About 22% of Canadians have high blood pressure, or hypertension. However, studies have shown that only 1 out of 5 people with hypertension have their blood pressure controlled.
- Conditions
- Hypertension, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- SCRIP-HTN (NCT00374270)
- Testing
- Lifestyle Counselling; Opinion Leader Influence Statements
- Where
- Canada
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Heart Failure, Congestive, Pulmonary Disease, Chronic Obstructive
Capturing Outcomes of Clinical Activities Performed by a Rounding Pharmacist Practising in a Team Environment
We, the researchers, propose to link a clinical pharmacist with an internal medicine or family medicine team to provide pharmaceutical care to all patients assigned to the team.
- Conditions
- Heart Failure, Congestive, Pulmonary Disease, Chronic Obstructive, Pneumonia, Diabetes Mellitus, Type 2
- Trial name
- NCT00351676
- Testing
- Integration of a team based clinical pharmacist, Optimizing therapeutic treatments, Optimizing processes of care
- Where
- 3 sites in Canada
- Volunteers
- 452 people
- Sponsor
- University of Alberta
Type 2 Hepatorenal Syndrome, Refractory Ascites
The Use of Drugs to Improve Kidney Function in Patients With Liver and Kidney Dysfunction
We will address the hypothesis that refractory ascites and Type 2 hepatorenal syndrome are mediated in part by diminished circulatory volume and that treatment with midodrine, octreotide and albumin can improve renal and patient…
- Trial name
- NCT00240045
- Testing
- Midodrine, albumin, octreotide LAR, midodrine, octreotide, albumin
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- University of Alberta
Inflammation, Cardiac Surgical Procedures
Inflammatory Responses to Lipid Emulsions in Children Before and After Open Heart Surgery
This study is a blinded, randomized, controlled prospective trial comparing immune response (sepsis, inflammatory response, pulmonary vasoconstriction) in 2 groups of infants less than 3-month old receiving pre and post…
- Trial name
- NCT00336908
- Testing
- a combination of MCT, LCT , and Fish Oil
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of Alberta
Infant, Premature
The Edmonton Randomised Controlled Trial of NIDCAP - Based Developmental Care
NIDCAP based developmental care is a method of looking after preterm infants that is guided by the infant's behavioural cues, and that actively involves parents in the care of their infant.
- Trial name
- NIDCAP (NCT00552383)
- Testing
- NIDCAP based developmental care
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of Alberta
Primary Biliary Cirrhosis
Study of Combivir for Patients With Primary Biliary Cirrhosis
This is a proof of principal study to determine whether combination anti-viral therapy with Combivir impacts on hepatic biochemistry in patients with primary biliary cirrhosis
- Trial name
- NCT00490620
- Testing
- Combination antiviral therapy
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 59 people
- Sponsor
- University of Alberta
Achilles Tendon Rupture
A Study Comparing Protected Early Weightbearing Versus Non-Weightbearing After Surgery for Achilles Tendon Rupture
The purpose of this study was to determine the effect of protected early weightbearing (PEWB) compared to non-weightbearing (NWB) after surgery for an Achilles tendon rupture (ATR) on health related quality of life (HRQL) in the…
- Trial name
- NCT00489749
- Testing
- Protected early weightbearing/Achilles tendon surgery
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- University of Alberta
Chronic Obstructive Pulmonary Disease, COPD
The Effect of Breathing Helium-Hyperoxia During Pulmonary Rehabilitation in Patients With COPD
The purpose of this study is to examine whether breathing helium-hyperoxia during exercise in a pulmonary rehabilitation program can improve the exercise tolerance and health related quality of life of patients with Chronic…
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD, Emphysema, Lung Diseases
- Trial name
- NCT00406705
- Testing
- Helium-Hyperoxia
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- University of Alberta
Osteoporosis, Hip Fracture
Randomized Trial of Osteoporosis Intervention Strategies in Hip Fracture Patients
Patients with hip fractures have suffered the most devastating consequence of osteoporosis; and yet, they are rarely if ever tested or treated for the condition, even though they remain at high risk of recurrent fracture.
- Trial name
- NCT00175175
- Testing
- Allied health professional-run osteoporosis service ("case-management")
- Where
- Canada
- Volunteers
- 220 people
- Sponsor
- University of Alberta