Clinical trials: sponsored by University of Alberta
End Stage Renal Disease on Dialysis
Diuretic Use in Hemodialysis Patients With Residual Renal Function
This pilot trial will evaluate the use of diuretic medications (furosemide and chlorthalidone) in participants on dialysis to see if these medications work to preserve existing kidney function, increase urine output, and reduce…
- Trial name
- DIURESED (NCT05915286)
- Testing
- Furosemide, Chlorthalidone
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of Alberta
Carbon Footprint in Anesthetic
Life Cycle Assessment of Different Types of Anesthetic
Following Ethics approval, all adult patients undergoing surgery to fix the wrist fracture will be approached and consent to undergo this study.
- Trial name
- NCT05385367
- Testing
- Regional anesthetic, General anesthetic, Combined general anesthetic and regional anesthetic
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of Alberta
Epilepsy, Temporal Lobe
Enhanced MRI Imaging in Healthy Participants and Participants With Epilepsy
Temporal lobe epilepsy (TLE) is a common type of epilepsy and one of the most likely to not be controlled by medication. For patients who do not respond to medication, surgery can result in a cure of seizures.
- Trial name
- NCT06483061
- Testing
- Ferumoxytol
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Peripheral Nerve Injuries
Electrical Stimulation to Enhance Peripheral Nerve Regeneration
The primary goal of this study is to quantify the functional deficits caused by injuries to the brachial plexus and peripheral nerve in the arm.
- Trial name
- NCT02403661
- Testing
- Post surgical electrical stimulation
- Where
- Canada
- Volunteers
- 136 people
- Sponsor
- University of Alberta
Children With Motor Impairments
Utilizing an EEG-Based BCI Game to Evaluate Cognitive Skills in Children With Motor Impairments
This project aims to validate an EEG-based brain-computer interface (BCI) game as a cognitive assessment tool for children with motor impairments.
- Trial name
- NCT07109830
- Testing
- Cognitive assessment, NEPSY-II
- Where
- 2 sites in Canada
- Volunteers
- 73 people
- Sponsor
- University of Alberta
Neurogenic Bladder, Post-operative Urinary Tract Infections
Antibiotic Prophylaxis for Neurogenic Bladder Botox
Injection of Botox into the bladder is a procedure used to treat neurogenic overactive bladder at the Dianne and Irving Kipnes Urology Centre in the Kaye Edmonton Clinic.
- Trial name
- NCT04791579
- Testing
- Ciprofloxacin
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- University of Alberta
Inflammatory Bowel Disease (IBD)
Clinical Investigation of MYIBDDiet App Developed for Inflammatory Bowel Disease (IBD) Patients to Self-manage Their Diet
The goal of this clinical trial is to learn if an app designed for diet education can help patients with inflammatory bowel disease (IBD) learn about healthy eating.
- Trial name
- NCT06683105
- Testing
- MyIBDDiet app
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Hip Fractures, Surgery
SiFi vs FNB Local Anesthesia for Hip Fracture Surgeries
The goal of this clinical trial is to compare two commonly used local/regional anesthesia techniques in adults patients undergoing hip fracture surgery.
- Conditions
- Hip Fractures, Surgery, Anesthesia, Local
- Trial name
- NCT06296758
- Testing
- Regional anesthesia
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- University of Alberta
Spastic Diplegia, Periventricular Leukomalacia
Randomized Controlled Trial of Early Intensive Leg Exercise to Improve Walking in Children With Diplegia
This is a randomized controlled trial, comparing 3 months of intensive leg exercise to standard physiotherapy care for the improvement of gross motor function in young children with spastic diplegia.
- Trial name
- NCT03672877
- Testing
- Intensive exercise
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Alberta
Diabetes, Surgery Related Complications Rate
Preoperative Optimization of Diabetic Patients
Diabetic patients, as part of preoperative evaluation, should have glycated hemoglobin (HbA1C) measured. HbA1C provides information on longterm glucose control.
- Trial name
- NCT06589466
- Testing
- Surgery
- Where
- Canada
- Volunteers
- 46,000 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Ulcerative Colitis
LFMT vs Placebo in New Biologic Start for Ulcerative Colitis
To compare the safety and efficacy of concomitant LFMT versus placebo in UC patients who are starting vedolizumab or ustekinumab.
- Trial name
- NCT05327790
- Testing
- Lyophilized fecal microbiota (LFMT)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Dry Needling, Physiotherapy
Physiotherapy Dry Needling Accuracy
The goal of this clinical trial is to learn if the addition of cadaver review improves: the accuracy of physiotherapists who practice dry needling. the perceived safety of dry needling by physiotherapists.
- Trial name
- NCT06845969
- Testing
- Education: dry needling theory, Education: Cadaver anatomy review
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Cerebral Palsy
Effectiveness of Robotic Gait Training and Physical Therapy for Children and Youth With Cerebral Palsy
Robot assisted gait training is seen as a promising intervention for improving the walking abilities of children with cerebral palsy, but research to support its effectiveness compared to best practice physical therapy is…
- Trial name
- NCT02391324
- Testing
- Lokomat (LOK), Gait focused physical therapy (fPT), LOK + fPT
- Where
- 3 sites in United States, Canada
- Volunteers
- 68 people
- Sponsor
- University of Alberta
Adult Congenital Heart Disease
HIIT Versus Moderate Continuous Training in ACHD
This study is a single center randomized controlled trial evaluating the effect of an exercise training intervention (interval training or moderate continuous training) compared to usual care (no training) on exercise capacity in…
- Trial name
- PhiT (NCT07546227)
- Testing
- Exercise Intervention
- Where
- Canada
- Volunteers
- 47 people
- Sponsor
- University of Alberta
Cytolytic Vaginosis
Cytolytic Vaginosis Multicentre Registry
The goal of this registry is to learn more about cytolytic vaginosis, a little known and controversial condition. The main questions the registry aims to answer are: What are risk factors of cytolytic vaginosis? Are there…
- Trial name
- NCT06228469
- Where
- 3 sites in Brazil, Canada and 1 more
- Volunteers
- 32 people
- Sponsor
- University of Alberta
Acute Ischemic Stroke
PET Perfusion Imaging Techniques and Comparing Them to CT Perfusion Imaging in Stroke
Adult patients who are diagnosed with an acute supratentorial ischemic stroke within 48 hrs of onset will be enrolled into the study. Participants will undergo both a CT Scan and PET scan within 7 days of onset.
- Trial name
- NCT04571177
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Depressive Disorder, Treatment-Resistant
rTMS With and Without Text4Support for the Treatment of Resistant Depression.
This study is a multicenter prospective, parallel design, two-arm, rater-blinded randomized controlled pilot trial. Participants will be randomly assigned to one of two treatment conditions.
- Trial name
- NCT05570344
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Repetitive Transcranial Magnetic Stimulation (rTMS) Plus Text4Support
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- University of Alberta
Spasticity, Muscle
Does ESWT With BoNTA Treatment Improve Outcomes When Compared to Standard Management for Upper Limb Spasticity Patient.
Background Effective management of spasticity, a debilitating and challenging condition afflicting many recovering from and living with neurological conditions, may reduce long term consequences such as limb contracture, skin…
- Trial name
- NCT05226637
- Testing
- ESWT (extra-corporeal shock wave therapy)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Stroke
The Whole Day Matters After Stroke (BIG-STEPS)
Goal of research program: To understand person-specific factors, such as imaging markers and activity patterns early after stroke, that may guide precision rehabilitation to optimize function and improve recovery. Objectives: 1.
- Trial name
- BIG-STEPS (NCT05753761)
- Testing
- Behaviour- & Imaging-Guided Stepping Training Early Post-Stroke (BIG STEPS) intervention
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- University of Alberta
Respiratory Failure
Transpulmonary Assessment for Individualized Lung Optimization in Obese Patients
This protocol describes a randomized controlled feasibility vanguard study designed to investigate the implementation and effects of esophageal pressure-guided positive end-expiratory pressure (PEEP) titration in patients with…
- Trial name
- TAILOR-PEEP (NCT07359261)
- Testing
- Esophageal pressure-guided PEEP titration, Standard care PEEP management
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of Alberta