Clinical trials: sponsored by University of Bern
Self-criticism
iCompassion: Internet-based Self-help for More Self-compassion
In this study, people who suffer from strong self-critical tendencies will be randomized to two study conditions. The first group receives an account to an internet-based self-help intervention.
- Trial name
- iCompassion (NCT02920320)
- Testing
- Internet-based self-help program
- Where
- Switzerland
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Bern
Alcohol Dependence
Telephone-Based Continuing Care for Alcohol Dependence
Alcohol dependency is the second most common psychiatric disorder and a major public health concern. As addictive disorders and now thought to be chronic disorders for many patients there is a need for the development of expanded…
- Trial name
- NCT02030093
- Testing
- Telephone-based counseling
- Where
- Switzerland
- Volunteers
- 317 people
- Sponsor
- University of Bern
Depressive Disorder, Major
E-Compared-CH: Comparative Effectiveness Research on Internet-based Depression Treatment - Swiss Trial
To compare the clinical and cost-effectiveness of blended Cognitive Behavioural Therapy (CBT) for adults with major depressive disorder (MDD) with treatment as usual (TAU) in Swiss patients in secondary care
- Trial name
- E-COMPARED_CH (NCT02410616)
- Testing
- Blended CBT, Treatment as usual
- Where
- 2 sites in Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Bern
Jaw, Edentulous, Partially, Dental Implants, Single-tooth
Long-term Effectiveness of Contour Augmentation in Sites With Early Implant Placement
In this prospective case series study, 20 patients with an implant-borne single crown following early implant placement with simultaneous contour augmentation will be followed for 10 years.
- Conditions
- Jaw, Edentulous, Partially, Dental Implants, Single-tooth, Grafting Bone
- Trial name
- NCT03252106
- Testing
- Contour augmentation with implant placement
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bern
Stroke
Clinical Reasoning Process of Physiotherapists When Observing Hemiplegic Gait
The goal of this study is to find out what clinical reasoning process physiotherapists undergo when observing hemiplegic patients gait.
- Trial name
- NCT02504073
- Testing
- No intervention
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Technical University of Bern
Gingival Recession, Emdogain
Gingival Recession Coverage With and Without Emdogain
Enamel matrix proteins have been shown to play a crucial role during tooth development and its supporting tissues. This is used in periodontal surgery where regeneration of lost tissues around the teeth is intended.
- Trial name
- NCT02230787
- Testing
- Recession coverage without Emdogain, Recession coverage with Emdogain
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Bern
Neuroscience of Dreaming, Healthy
The Impact of the Opiate Antagonist Naltrexone on the Emotional Valence of Dreams
In this study, the investigators pose the question which influence the opioid circuit has on positive valent situations in dreams.
- Trial name
- NCT02792140
- Testing
- Naltrexone
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Bern
Dental Caries
Validation of Near-infrared Light Transillumination for Interproximal Enamel Caries Detection
The aim of this study is to validate a near-infrared light transillumination device (DIAGNOcam, KaVo, Biberach, Germany) for interproximal enamel caries detection and compare it with the established diagnostic methods (visual…
- Trial name
- NCT02657538
- Testing
- Non invasive caries treatment, Invasive caries treatment, Near-infrared light transillumination device (DIAGNOcam, KaVo, Biberach, Germany)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Bern
Mastication Disorder, Stroke
Oral Tactile Sensitivity in Stroke Patients
Orofacial impairment following stroke frequently involves a reduced chewing performance and dysphagia. This study investigated the sensitivity of oral tissues following stroke and its potential impact on chewing efficiency.
- Conditions
- Mastication Disorder, Stroke, No Problem Chewing, Dysphagia
- Trial name
- NCT02822391
- Testing
- observation
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Bern
Macular Degeneration
Assessment of Scan Quality of Sparse OCT Retina Scanner (MimoStudy01)
Optical Coherence Tomography (OCT) is an established non-invasive medical imaging technique ophthalmologists use to diagnose and monitor retinal diseases such as age-related macular degeneration (AMD).
- Trial name
- NCT02555995
- Testing
- OCT scan (as yet unnamed)
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Bern
Suicide Attempt, Suicide
ASSIP, Attempted Suicide Short Intervention Program. Two Year Follow-Up Study
Objective Attempted suicide is the main risk factor for repeated suicidal behavior. However, evidence of the effectiveness of follow-up treatments for these patients is limited.
- Conditions
- Suicide Attempt, Suicide, Suicidal Ideation
- Trial name
- ASSIP (NCT02505373)
- Testing
- Attempted Suicide Short Intervention Program (ASSIP), Control Group (CG)
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Bern
Liver Diseases, Liver Neoplasms
Quality of Life After Liver Resection
Patients with malignant diseases are increasingly receiving more extensive hepatic resections, with im-proved preoperative and postoperative care leading to a reduced postoperative morbidity and mortality.
- Trial name
- NCT00681499
- Where
- Switzerland
- Volunteers
- 198 people
- Sponsor
- University of Bern
Blood Loss, Surgical
Point of Care Coagulation Testing in Patients Undergoing Major Surgery
Bleeding is a frequent complication during surgery. The peri-operative administration of blood products, including packed red blood cells, thrombocytes and fresh frozen plasma (FFP), is often deemed necessary.
- Trial name
- POC-OP (NCT00656396)
- Testing
- Coagucheck XS Plus (Point of care monitor of coagulation intraoperative), Control Intervention
- Where
- Switzerland
- Volunteers
- 228 people
- Sponsor
- University of Bern
Caregivers, Brain Injury
OSCAR - An Internet-based Supportive Coaching for Informal Caregivers of Adult Individuals With an Acquired Brain Injury
This is an intervention study for informal caregivers of adult patients with an acquired brain injury (stroke, traumatic brain injury or cerebral haemorrhage).
- Trial name
- NCT01112969
- Testing
- Internet-based supportive coaching OSCAR, Waiting-list control group (TAU)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Bern
Asthma
Effectiveness of Anthroposophic Speech Therapy in Patients With Asthma
Anthroposophic therapeutic speech is a complementary method that indirectly influences breathing and uses specific vowels, consonants, syllables and metres depending on the indication.
- Trial name
- NCT02501824
- Testing
- anthroposophic therapeutic speech
- Where
- Switzerland
- Volunteers
- 49 people
- Sponsor
- University of Bern
Adjustment Disorders, Non-progressive Brain Injury
Does an Integrative Neuro-psychotherapy Program Foster the Adjustment in Depressed Stroke Patients? A Randomized Controlled Study.
This is an intervention study with patients after a non-progressive brain injury who suffer from depression. It will determine whether an integration of neuropsychological and psychotherapeutic techniques and an additional…
- Trial name
- NCT01039857
- Testing
- Neuropsychological Therapy, cognitive behavioral therapy, solution focused therapy, Integrative Neuro-Psychotherapy
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- University of Bern
Dimensional Alterations
Dimensional Soft and Hard Tissue Alterations Following Single Tooth Extraction in the Anterior Maxilla - A Prospective Clinical Study
Bone modeling after tooth extraction has a major consequence on implant therapy, in particular in the esthetic zone. In esthetic sites, no tissue loss should occur if an optimal esthetic outcome is expected.
- Trial name
- Alterations (NCT02403700)
- Testing
- Cone beam computed tomography (CBCT)
- Where
- Switzerland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Bern
Coronary Heart Disease
Randomized Trial Comparing Titan Stent With Zotarolimus-Eluting Stent
A Randomized Comparison of a Titanium-Nitride-Oxide Coated Stent (Helistent Titan2, Hexacath) With a Zotarolimus-Eluting Stent (EndeavorTm, Medtronic) for Percutaneous Coronary Intervention
- Trial name
- NCT00492908
- Testing
- Helistent Titan2 (Titanium coated stent), EndeavorTM (Zotarolimus-Eluting Stent)
- Where
- Switzerland
- Volunteers
- 303 people
- Sponsor
- University of Bern
Crohn Disease
Significance of Ficolin 2 in the Determination of Serological Activity in Chronic Inflammatory Bowel Disease
Background Determining disease activity in IBD is sometimes difficult and, to be accurate, requires endoscopy. The serum marker CRP has not proven sufficiently valuable as a marker for IBD specific inflammation.
- Trial name
- NCT01473927
- Testing
- Endoscopy
- Where
- 3 sites in Switzerland
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Bern
Respiratory Tract Infections, Urinary Tract Infections
Intervention Study to Improve Antibiotic Prescription in Outpatient Care
Antimicrobial resistance has become a world-wide problem and antibiotic consumption is a major driving force for the development of resistance.
- Trial name
- SAPI (NCT01358916)
- Testing
- Mailing of antibiotic therapy guidelines to the sentinel physicians
- Where
- Switzerland
- Volunteers
- 140 people
- Sponsor
- University of Bern