Clinical trials: sponsored by University of Bern
Fatigue, Breast Cancer
Eurythmy Therapy (ERYT) as a Treatment Option for Fatigue in Metastatic Breast Cancer Patients
Cancer related fatigue (CRF) is the most burdening symptom in breast cancer patients, and prevalence exceeds 75% in patients with metastatic disease.
- Trial name
- ERYT (NCT04024267)
- Testing
- Eurythmy therapy, CoordiFit
- Where
- 11 sites in Switzerland
- Volunteers
- 19 people
- Sponsor
- University of Bern
Dietary Behavior, Stress
Dietary Plant Hormone and Mental Health
The aim of this cross-sectional online study is to investigate the association between regular feeding behavior and stress, sleep as well as anxiety and depressive symptoms in healthy subjects.
- Conditions
- Dietary Behavior, Stress, Sleep, Depression, Anxiety
- Trial name
- NCT05276479
- Testing
- Anonymous online survey on dietary habits and mental health
- Where
- Switzerland
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- University of Bern
Weak; Senile, Old Age; Debility
Comparison of the Functional Status, Psychosocial Aspects and Discharge Locations of Geriatric Patients Before and After Inpatient Geriatric Rehabilitation
Due to demographic change in Switzerland, the proportion of older people in the population is expected to increase. It is therefore important that people in old age remain in the best of health and maintain their independence for…
- Conditions
- Weak; Senile, Old Age; Debility, Movement Disorders, Quality of Life
- Trial name
- NCT07131865
- Where
- Switzerland
- Volunteers
- 753 people
- Sponsor
- University of Bern
Childhood Cancer, Cancer-related Problem/Condition
Effect of Cognitively Challenging Physical Activity on Executive Functions in Pediatric Cancer Patients
When it comes to exercise and sport for children and adolescents with cancer, there is often still the opinion that physical activity has a negative effect on the weakened body suffering from cancer.
- Conditions
- Childhood Cancer, Cancer-related Problem/Condition, Cognitive Side Effects of Cancer Therapy, Physical Activity
- Trial name
- KiKli Fit (NCT06839794)
- Testing
- Cognitively challenging physical activity for paediatric cancer patients, Physical activity recommendations
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University of Bern
Schizophrenia
Brain Stimulation And Group Therapy to Improve Gesture and Social Skills in Psychosis (BrAGG-SoS)
Randomized, double-blind, placebo-controlled clinical trial testing the effects of 10 sessions of continuous theta burst stimulation and the effects of 16 sessions of social cognitive remediation therapy on gesture performance…
- Trial name
- BrAGG-SoS (NCT04106427)
- Testing
- continuous theta burst stimulation (cTBS), social cognitive remediation therapy (SCRT)
- Where
- Switzerland
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Bern
Healthy
Healthy University Bern Through Yoga - A Worksite Wellness Intervention
This study aims to research the effect of a 8-week long worksite yoga intervention on the perceived health of the University of Bern employees.
- Trial name
- NCT05101226
- Testing
- Yoga attended in person, Yoga attended online
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Bern
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 7 of 7)
NOTE: This is the seventh of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02919137
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Bern
Smoking Cessation
The ESTxENDS Trial- Electronic Nicotine Delivery Systems as an Aid for Smoking Cessation-extension of Follow-up
Cigarette smoking is the leading cause of preventable death in Switzerland and still more than a quarter of the Swiss population smokes cigarettes.
- Trial name
- ESTxENDS (NCT04236791)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, Smoking cessation counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 1,246 people, healthy volunteers welcome
- Sponsor
- University of Bern
Suicidal Ideation, Suicide Attempt
Expansion and Reevaluation of the Implicit Association Test in Suicide Ideators and Suicide Attempters
A new approach to investigate suicidal processes belongs to the broader neurocognitive picture and are so-called implicit associations.
- Trial name
- IAT-S (NCT04585802)
- Where
- Switzerland
- Volunteers
- 447 people
- Sponsor
- University of Bern
Periodontitis
Novel Protocol for Supportive Periodontal Therapy
Supportive periodontal therapy (SPT) succeeds the active phase of periodontal therapy. SPT includes repeated supra- and subgingival scaling and root planing (SRP) at all sites with bleeding on probing and pocket depths ≥ 4-5 mm.
- Trial name
- GBM (NCT05799261)
- Testing
- Control (standard protocol), Test (Guided Biofilm management)
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Toe Flexor Strength
Improving Foot Strength in Vocational Ballet Dancers
Professional dancers subject their feet to high forces through frequent jumping, repeated heel rises, insufficient shoe cushioning, and a high degree of foot mobility.
- Trial name
- NCT06589050
- Testing
- "Toe flexor device" experimental group, "Inclined Heel Rise" experimental group
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Bern
Alzheimer Disease, Dementia
Tablet-based Cognitive Training
Today the therapy options for dementia due to Alzheimer's disease (AD) are limited. One recommended intervention is cognitive stimulation.
- Conditions
- Alzheimer Disease, Dementia, Mild Cognitive Impairment
- Trial name
- NCT04452864
- Testing
- Computerized Cognitive Training, Documentaries with delayed Computerized Cognitive Training
- Where
- 2 sites in Switzerland
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University of Bern
Optic Neuritis, Transverse Myelitis
Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)
The Swiss-Ped-IBrainD is a national patient registry that collects information on diagnosis, symptoms, treatment, and follow-up of pediatric patients with an inflammatory brain disease in Switzerland.
- Conditions
- Optic Neuritis, Transverse Myelitis, Acute Disseminated Encephalomyelitis, Multiple Sclerosis
- Trial name
- NCT05017142
- Where
- 13 sites in Switzerland
- Volunteers
- 500 people
- Sponsor
- University of Bern
Healthy
Effects of Stochastic Whole-body Vibration Training on Balance and Executive Functions
Falls represent a significant financial burden, costing millions of dollars annually in Switzerland (SUVA, 2022). Good cognitive abilities and good balance represent modifiable protective factors against falls (Kurz, 2008).
- Trial name
- NCT06629298
- Testing
- 5Hz Stochastic Resonance Whole-Body Vibration Training, 2 Hz Stochastic Resonance Whole-Body Vibration Training
- Where
- Switzerland
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Bern
Diabetes, Hypoglycemia
Investigating the Relationship Between Nocturnal Glucose Levels and Motion During Sleep
In this study the investigators will explore whether the motion during sleep of people with diabetes changes as a function of the blood glucose levels.
- Conditions
- Diabetes, Hypoglycemia, Hyperglycemia
- Trial name
- Moonwalk (NCT05609175)
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- University of Bern
Schizophrenia; Psychosis, Schizophrenia and Related Disorders
Accelerated rTMS for Psychomotor Slowing
The goal of this clinical trial is to optimize the treatment of psychomotor slowing in patients with schizophrenia using Transcranial Magnetic Stimulation (TMS).
- Conditions
- Schizophrenia; Psychosis, Schizophrenia and Related Disorders, Schizo Affective Disorder, Brief Psychotic Disorder
- Trial name
- ATMSSlowing (NCT06134661)
- Testing
- cTBS (continuous Theta Burst Stimulation)
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- University of Bern
Tooth Loss, Bone Graft; Complications
Patient-reported Outcome Measures After Implant Placement With Contour Augmentation Procedure
Maintaining the general health and well-being of patients is the main goal of dental therapy. However, tooth extraction is indicated when teeth cannot be maintained in a status compatible with health, adequate esthetics…
- Conditions
- Tooth Loss, Bone Graft; Complications, Patient Satisfaction, Patient Acceptance of Health Care
- Trial name
- NCT05890170
- Testing
- Patient Reported Outcomes Measures
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Bern
Diabetes Mellitus, Metabolic Disease
Analysis of Volatile Organic Compounds in Patients With Type 1 Diabetes in Induced Hypoglycaemia With a Breath Analyser
The breath analysis (BreathSpec® device) data of all participants that were included into the VAARA study (NCT05771090) will be analysed, this includes data from up to 40 breath samples from each of the 10 participants who…
- Conditions
- Diabetes Mellitus, Metabolic Disease, Glucose Metabolism Disorders, Endocrine System Diseases
- Trial name
- VAARABreath (NCT05933616)
- Testing
- Device: Sokru device
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- University of Bern
Edentulous Mouth
Zirconia Bars for Mandibular Implant Overdentures
Purpose: To assess the clinical and radiographic outcomes of computer-aided designed and manufactured (CAD-CAM) zirconia bars supporting mandibular implant-retained overdentures (IODs) after a 3-year follow-up.
- Trial name
- NCT06471881
- Testing
- Two mandibular implants
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Bern
Dental Implant Failed
Narrow-diameter Implants Replacing Maxillary Lateral Incisors
To present the 5-year clinical, radiographic, and aesthetic outcomes in patients with congenitally missing lateral incisors (MLIs) rehabilitated with two narrow-diameter implants (NDIs).
- Trial name
- NCT06500923
- Testing
- Oral rehabilitation by means of implant-supported single unit crowns
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Bern