Clinical trials: sponsored by University of Bern
Social Anxiety, Social Anxiety Disorder
SOPHIE: Online-intervention for Prevention and Treatment of Social Anxiety in Adolescents
This study's aim is to investigate the efficacy of the online-intervention SOPHIE. SOPHIE is an online-intervention for adolescents with social anxiety.
- Trial name
- SOPHIE (NCT04782102)
- Testing
- SOPHIE Intervention
- Where
- Switzerland
- Volunteers
- 128 people
- Sponsor
- University of Bern
Social Anxiety Disorder (Social Phobia)
Optimizing Cognitive-behavioral Therapy for Social Anxiety Disorder Using the Factorial Design
Social Anxiety Disorder (SAD) is characterized by a marked fear of negative evaluation in social situations. It is the third most common psychiatric disorder and highly disabling (American Psychiatric Association, 2000).
- Trial name
- OPTIMIZE (NCT04879641)
- Testing
- Exposure, Attention Training, Cognitive Restructuring
- Where
- Switzerland
- Volunteers
- 464 people
- Sponsor
- University of Bern
Quality of Life, Stigma, Social
App-based Psychosocial Intervention to Enhance Quality of Life in Arabic-speaking Refugees Residing in Switzerland
The ongoing warfare and economic instability in the Middle East and in North Africa causes many people to leave their home countries.
- Conditions
- Quality of Life, Stigma, Social, Depression, PTSD
- Trial name
- Sui (NCT05651737)
- Testing
- Sui App (SRK)
- Where
- Switzerland
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Bern
Mild Cognitive Impairment
Real-time fMRI Neurofeedback in Patients With MCI
Increased activity in the hippocampus (i.e., hyperactivity) during a fMRI memory task was found in patients with Mild Cognitive Impairment due to Alzheimer's disease (MCI).
- Trial name
- NCT04020744
- Testing
- real-time fMRI based neurofeedback from the hippocampus, real-time fMRI based neurofeedback from another brain area
- Where
- 2 sites in Switzerland
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Bern
Schizophrenia and Related Disorders
Transcranial Direct Current Stimulation (tDCS) to Improve Gesture Control
The majority of schizophrenia patients is impaired in hand gesture performance, which contributes to poor functional outcome and poor communication skills.
- Trial name
- GesttDCS (NCT03463902)
- Testing
- left IFG anodal, left IFG cathodal, left IPL anodal
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Bern
Stress Reaction
Breaking Bad News - Optimizing Stress Response and Communication Performance in Medical Students
Breaking bad news (e.g., telling patients that they have cancer) is not only very stressful for the patients concerned, but also for the physicians delivering the diagnosis.
- Trial name
- BPSM (NCT05037318)
- Testing
- Stress arousal reappraisal, Worked examples
- Where
- Switzerland
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- University of Bern
Healthy, Mild Cognitive Impairment
Does Acoustic Stimulation During Sleep Boost Slow Wave Sleep and Memory Performance?
With aging the amount of slow wave sleep decreases drastically and this disruption is markedly exaggerated in older adults suffering from mild cognitive impairment and Alzheimer's disease.
- Conditions
- Healthy, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT04277104
- Testing
- Closed loop acoustic stimulation
- Where
- Switzerland
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Bern
Healthy Aging
Modulating Prospective Memory in Older Adults With Non-invasive Brain Stimulation
Prospective memory is the ability to remember to carry out intentions with a certain delay (e.g. remember to buy stamps when passing a postal office).
- Trial name
- NCT04882527
- Testing
- Non-invasive brain stimulation
- Where
- Switzerland
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Bern
Major Depressive Disorder
Sleep Subtypes in Adolescent Depression
The purpose of this study is to compare sleep neurophysiology and behavior in adolescents with MDD with hypersomnia (MDD-HYP) and insomnia (MDD-INS) with healthy controls (HC).
- Trial name
- NCT03742960
- Testing
- Behavioral Sleep Restriction
- Where
- Switzerland
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Bern
Severe Mental Disorder
Independent Housing and Support for People With Severe Mental Illness
Background: Adequate and stable housing conditions are fundamental for the psychiatric rehabilitation of individuals with severe mental illness (SMI).
- Trial name
- NCT03815604
- Testing
- Independent Housing and Support (IHS), Residential Care Settings and other Treatment as Usual (RCS/TAU)
- Where
- 2 sites in Switzerland
- Volunteers
- 143 people
- Sponsor
- University of Bern
Dental Implant
Long-term Study in Early Loaded Hydrophilic Surface Implants
Objective: To assess the clinical outcomes and patient satisfaction of early loaded implants with a hydrophilic, moderately rough surface for partially edentulous patients after a follow-up of 8.5 to 9.5 years.
- Trial name
- NCT06138392
- Testing
- Dental implant (ELEMENT RC INICELL, Thommen Medical)
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Bern
Smoking Cessation, Depression
The ESTxENDS Trial- Substudy on the Effects of Using Electronic Nicotine Delivery Systems (ENDS) on Depression
--> This is a substudy of the main ESTxENDS trial (NCT03589989). Depression outcomes should be considered secondary outcomes of the main smoking cessation outcome formulated in NCT03589989.
- Trial name
- ESTxENDS (NCT03603340)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, Smoking cessation counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 1,246 people, healthy volunteers welcome
- Sponsor
- University of Bern
Smoking Cessation, Respiratory Disease
The ESTxENDS Trial- Substudy on the Effects of Using Electronic Nicotine Delivery Systems (ENDS/Vaporizer/E-cig) on Respiratory Symptoms
--> This is a substudy of the main ESTxENDS trial (NCT03589989). Respiratory symptoms outcomes should be considered secondary outcomes of the main smoking cessation outcome formulated in NCT03589989.
- Trial name
- ESTxENDS (NCT03632421)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, Smoking cessation counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 1,246 people, healthy volunteers welcome
- Sponsor
- University of Bern
Smoking Cessation, Micronuclei
ESTxENDS Trial: MN Substudy - Micronuclei in Buccal Epithelium, a Surrogate Measure of Future Cancer Risk, Induced by Electronic Nicotine Delivery Systems (ENDS/Vaporizer/E-cig)
--> This is a substudy of the main ESTxENDS trial (NCT03589989). Micronuclei in buccal epithelial outcomes should be considered secondary outcomes of the main smoking cessation outcome formulated in NCT03589989.
- Trial name
- ESTxENDS (NCT04244773)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, Smoking cessation counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 1,246 people, healthy volunteers welcome
- Sponsor
- University of Bern
Smoking Cessation, Oxidative Stress
ESTxENDS Trial- Substudy on Oxidative Stress Induced by Electronic Nicotine Delivery Systems (ENDS) Measured in EBC
--> This is a substudy of the main ESTxENDS trial (NCT03589989). Oxidative stress outcomes should be considered secondary outcomes of the main smoking cessation outcome formulated in NCT03589989.
- Trial name
- ESTxENDS (NCT03612453)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, Smoking cessation counseling
- Where
- Switzerland
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of Bern
Smoking Cessation, Pulmonary Disease
The ESTxENDS Trial: Pulmonary Function Substudy
--> This is a substudy of the main ESTxENDS trial (NCT03589989). Pulmonary function outcomes should be considered secondary outcomes of the main smoking cessation outcome formulated in NCT03589989.
- Trial name
- PulmENDS (NCT03938298)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, Smoking cessation counseling
- Where
- 2 sites in Switzerland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Bern
Smoking Cessation, Olfactory Disorder
The ESTxENDS Trial- Substudy on Effects of Using Electronic Nicotine Delivery Systems (ENDS) on Olfactory Function
--> This is a substudy of the main ESTxENDS trial (NCT03589989). Olfactory function outcomes should be considered secondary outcomes of the main smoking cessation outcome formulated in NCT03589989.
- Trial name
- ESTxENDS (NCT04617444)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, Smoking cessation counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- University of Bern
Smoking Cessation, Oxidative Stress
ESTxENDS Trial-Substudy on Oxidative Stress Induced by Electronic Nicotine Delivery Systems (ENDS) Measured in Urine
--> This is a substudy of the main ESTxENDS trial (NCT03589989). Oxidative stress outcomes should be considered secondary outcomes of the main smoking cessation outcome formulated in NCT03589989.
- Trial name
- ESTxENDS (NCT03612375)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, smoking cessation counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 1,246 people, healthy volunteers welcome
- Sponsor
- University of Bern
Smoking Cessation, Sleep
The ESTxENDS Trial- Substudy on the Effects of Using Electronic Nicotine Delivery Systems (ENDS) on Sleep Quality.
--> This is a substudy of the main ESTxENDS trial (NCT03589989). Sleep quality outcomes should be considered secondary outcomes of the main smoking cessation outcome formulated in NCT03589989.
- Trial name
- ESTxENDS (NCT03603353)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, Smoking cessation counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 1,246 people, healthy volunteers welcome
- Sponsor
- University of Bern
Smoking Cessation, Toxicity
The ESTxENDS Trial- Substudy on the Effect on Toxins From Using Electronic Nicotine Delivery Systems (ENDS/Vaporizer/E-cig)
--> This is a substudy of the main ESTxENDS trial (NCT03589989). Toxins outcomes should be considered secondary outcomes of the main smoking cessation outcome formulated in NCT03589989.
- Trial name
- ESTxENDS (NCT03612544)
- Testing
- ENDS (Vaporizer/e-cig) and smoking cessation counseling, Smoking cessation counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 1,246 people, healthy volunteers welcome
- Sponsor
- University of Bern