Clinical trials: sponsored by University of Bern
Radiation Dermatitis
Urtica Comp. Gel for Prevention and Therapy of Radiation Dermatitis
A randomized controlled trial comparing Urtica comp. gel (Swissmedic listed medication in the category of "Anthroposophic Medication without Indication") against standard skin care, examining its effect in prevention and…
- Trial name
- Urticacomp (NCT03494205)
- Testing
- Urtica comp. gel, institutional standard skin care "Excipial-Hydrolotion"
- Where
- Switzerland
- Volunteers
- 31 people
- Sponsor
- University of Bern
Smoking Cessation
The ESTxENDS Trial- Electronic Nicotine Delivery Systems (ENDS/Vaporizer/E-cigarette) as an Aid for Smoking Cessation.
Cigarette smoking is the leading cause of preventable death in Switzerland and still more than a quarter of the Swiss population smokes cigarettes.
- Trial name
- ESTxENDS (NCT03589989)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, Smoking cessation counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 1,246 people, healthy volunteers welcome
- Sponsor
- University of Bern
Alcohol Dependence
Learning to Resist the Urge: Inhibition Training in Abstinent Patients With Alcohol Use Disorders
The study aims to investigate the effects of a short computerized training as a therapeutic add-on to standard therapy in patients with alcohol-use disorder.
- Trial name
- INTRA (NCT02968537)
- Testing
- Alc-IT (50/50) (morning), Alc-IT (75/25) (morning), Control-training (morning)
- Where
- 3 sites in Switzerland
- Volunteers
- 242 people
- Sponsor
- University of Bern
Ultrasonography, Educational Techniques
Near-peer Tutoring Compared With a Standard Faculty-led Course for Undergraduate Training in Abdominal Ultrasound.
Background: Ultrasound has become clinical skill widely used in most medical disciplines. Institutions are changing their curricula to implementing basic ultrasound knowledge, often supplementing traditional teaching with…
- Trial name
- SIGNATURE (NCT04114812)
- Testing
- Blended learning, Standard course
- Where
- 3 sites in Switzerland
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Bern
Transportation Accidents, Drunk Driving
Design and Implementation of a Drunk Driving Detection System
To analyse driving behavior of individuals under the influence of alcohol using a validated research driving simulator. Based on the driving variables provided by the simulator the investigators aim at establishing algorithms…
- Conditions
- Transportation Accidents, Drunk Driving, Alcohol Drinking, Impaired Driving
- Trial name
- DRIVE (NCT04980846)
- Testing
- Driving under the influence of alcohol with a driving simulator
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Bern
Adjustment Impairment, Accident
SelFIT: Internet-based Treatment for Adjustment Problems After an Accident
In this study, people who suffer from adjustment problems after having experienced an accident will be randomized to one of two study groups.
- Conditions
- Adjustment Impairment, Accident, Adjustment Disorders, Mental Disorder
- Trial name
- SelFIT (NCT03785912)
- Testing
- Internet-based self-help
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- University of Bern
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 1 of 7)
NOTE: This is the first of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02882516
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 2 of 7)
NOTE: This is the second of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02882529
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 3 of 7)
NOTE: This is the third of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02882542
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Bern
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 4 of 7)
NOTE: This is the fourth of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02919228
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Psychological Distress, Adjustment, Psychological
ROCO - Self-help for People With Psychological Distress Due to the Covid-19 Situation
As part of the ROCO project, the University of Bern is investigating an online self-help program for people who are psychologically distressed due to the situation surrounding Covid-19.
- Conditions
- Psychological Distress, Adjustment, Psychological, Coronavirus
- Trial name
- ROCO (NCT04380909)
- Testing
- Internet-based self-help, Internet-based self-help after 3 weeks
- Where
- Switzerland
- Volunteers
- 107 people
- Sponsor
- University of Bern
Psychomotor Retardation, Psychomotor Slowing
Transcranial Magnetic Stimulation (TMS) for Motor Symptoms in Psychiatric Disorders
Psychomotor slowing may occur in major psychiatric disorders, such as major depressive disorders or schizophrenia spectrum disorders. It refers to slowing of fine motor skills, motor planning and gross motor behavior.
- Conditions
- Psychomotor Retardation, Psychomotor Slowing, Schizophrenia and Related Disorders, Major Depressive Disorder
- Trial name
- NCT03275766
- Testing
- DLPFC facilitatory, SMA inhibitory, SMA facilitatory
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- University of Bern
Depression Mild, Depression Moderate
Factorial Trial Investigating Outcome and Adherence Relevant Factors in an Online Self-help Intervention for Depression
A vast amount of studies show that online interventions are suitable to reduce symptoms of mental illness as for instance depression or anxiety.
- Trial name
- HERMES (NCT04318236)
- Testing
- HERMES (Online Self-Help Intervention based on problem-solving therapy)
- Where
- Switzerland
- Volunteers
- 316 people
- Sponsor
- University of Bern
Multimorbidity, Polypharmacy
Optimizing PharmacoTherapy In the Multimorbid Elderly in Primary CAre: the OPTICA Trial
The objective of this randomized controlled trial (RCT) is to evaluate whether the Systematic Tool to Reduce Inappropriate Prescribing (STRIP), put into practice through the STRIP Assistant (STRIPA) and implemented by general…
- Trial name
- OPTICA (NCT03724539)
- Testing
- STRIPA intervention
- Where
- Switzerland
- Volunteers
- 323 people
- Sponsor
- University of Bern
Uterine Cervical Neoplasms, HIV/AIDS
Screening Test Accuracy of Gynocular™, HR-HPV Testing, VIA for Detection of Cervical Neoplastic Lesions, in Women Living With HIV
Cervical cancer in HIV-positive women is largely preventable through regular screening. The World Health Organization (WHO) recommends cervical screening for HIV-positive women every three years.
- Trial name
- NCT03931083
- Testing
- Screening for CIN2+/HSIL
- Where
- Zambia
- Volunteers
- 450 people
- Sponsor
- University of Bern
Educational Techniques
The Effect of a Structured, Home-based Interview With a Patient on First-year Medical Students' Patient-centredness.
Background Doctors are regarded as professionals, and specific teaching on professional behaviour is considered important in many countries.
- Trial name
- NCT03722810
- Testing
- Intervention
- Where
- Switzerland
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- University of Bern
Jaw, Edentulous, Partially, Dental Implant Failed
Survival and Success Rates of 6mm Implants With a Micro-rough Surface After 4.5 - 18.2 Years in Function
In this retrospective study, approximately 60 patients treated with 6mm short implants (Straumann, SLA (sandblasted, large-grit, acid-etched surface), SLActive (sandblasted, large-grit, acid-etched, hydrophilic surface), 4.1 or…
- Conditions
- Jaw, Edentulous, Partially, Dental Implant Failed, Implant Complication
- Trial name
- NCT04017026
- Testing
- Implantation
- Where
- Switzerland
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Bern
Dental Implant Failed
Retrospective Study on Clinical Performance of Screw-retained Implant Crowns
Survival and success rates of all-ceramic implant-supported fixed reconstructions fabricated with CAD/CAM technology after at least one year in function.
- Trial name
- NCT04370314
- Testing
- Dental prosthetics
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Bern
Healthy, Mild Cognitive Impairment
tES Effects on Associative Memory Performance
Previous studies showed that transcranial electric stimulation (tES) applied over the prefrontal cortex improves cognitive performance in healthy elderly adults as well as in patients suffering from mild cognitive impairment or…
- Conditions
- Healthy, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT03351452
- Testing
- real anodal transcranial direct current stimulation, real transcranial alternating current stimulation
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Bern
Healthy, Mild Cognitive Impairment
Supporting Episodic Memory With Transcranial Direct Current Stimulation in Healthy Controls and Dementia Patients
Previous studies showed that anodal tDCS applied over the dorsolateral prefrontal cortex (DLPFC) improved episodic memory performance, indicating a possible use as an intervention for patients suffering from memory impairments.
- Conditions
- Healthy, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT03227185
- Testing
- real anodal transcranial direct current stimulation (tDCS)
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Bern