Clinical trials: sponsored by University of British Columbia
Cognitive Impairment, Preoperative Cognitive Impairment
Reliability In Neurocognitive Telemedicine Screening (RING)
Perioperative neurocognitive disorders are common after surgery and pre-existing cognitive impairment is an important risk factor.
- Conditions
- Cognitive Impairment, Preoperative Cognitive Impairment, Perioperative Neurocognitive Disorders, Neurocognitive Function
- Trial name
- NCT07760545
- Testing
- Modified Mini-Cog Telephone Assessment
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- University of British Columbia
Vaginismus, Difficulties With Vaginal Penetration
Implementing Virtual Reality Exposure Therapy for Vaginismus: From Efficacy to Clinical Integration (VIVID 3)
Vaginismus, a condition characterized by involuntary tightening of the pelvic floor muscles due to strong fear of vaginal insertion, impact ≥6% of the female population and can make vaginal intercourse and medical exams…
- Trial name
- VIVID 3 (NCT07747298)
- Testing
- Implementation of Virtual Reality Exposure
- Where
- Canada
- Volunteers
- 167 people
- Sponsor
- University of British Columbia
PreDiabetes
Small Steps for Big Changes - Healthy Cities Implementation Science
Small Steps for Big Changes (SSBC) is a diet and exercise counselling program that significantly reduces the risk of developing Type 2 Diabetes (T2D).
- Trial name
- HCIS (NCT06440395)
- Testing
- Behavioural: Small Steps for Big Changes Diabetes Prevention Program
- Where
- 12 sites in Canada
- Volunteers
- 4,400 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Intraoperative Pain
Sensory Stimuli During Cesarean Delivery
During a cesarean delivery (C-section), most patients are awake and receive spinal or epidural anesthesia to block pain from the lower body.
- Trial name
- PIONEER-MC (NCT07340970)
- Testing
- Patient-initiated request for pharmacological intervention during cesarean delivery
- Where
- Canada
- Volunteers
- 1,005 people
- Sponsor
- University of British Columbia
Type 2 Diabetes
DiEt ChoIce to Promote Type 2 Diabetes rEmission
Type 2 diabetes is typically viewed as a chronic, progressive, and lifelong condition. Patients and their healthcare providers "manage" type 2 diabetes through lifestyle modifications and various types of medications designed to…
- Trial name
- DECIDE (NCT05710900)
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Diabetes in Children, Diabetes Type 1
Intelligent Care Platform - Quasi-Experimental Trial
This study will measure the implementation and effectiveness of an intervention, the use of a digital health tool, Haibu Diabetes, for the management of pediatric type 1 diabetes (T1D), on clinical outcomes.
- Trial name
- UBColumbia (NCT07712809)
- Testing
- Digital Diabetes Care Platform
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of British Columbia
Immunometabolism, Mitochondrial Function, Bioenergetics
Independent and Combined Effects of Short-term Sulforaphane Supplementation and Exercise on Immunometabolism in Healthy Adults
The study consist of 3 interventional periods which will be completed by each consenting participant in a randomized, crossover fashion. The interventional periods will be separated by a minimum 1 week washout period.
- Conditions
- Immunometabolism, Mitochondrial Function, Bioenergetics, Inflammation
- Trial name
- EXSFN (NCT07668596)
- Testing
- Sulforaphane-rich Broccoli Sprout Extract, High Intensity Interval Treadmill Running
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Breast Reconstruction, Breast Cancer
Access My Breast Cancer Care App
The Access my Breast Cancer Care application was developed by a multidisciplinary team with the intention of providing breast cancer patients with a centralized area to navigate their journey.
- Trial name
- NCT07696637
- Testing
- Access My Breast Cancer Care App, Standard Pathway
- Where
- 2 sites in Canada
- Volunteers
- 148 people
- Sponsor
- University of British Columbia
RSV Immunization, HIV
Study of HIV-Exposed Pregnancies and Transplacental Antibody Delivery Following RSVpreF
Respiratory syncytial virus (RSV) is the leading cause of hospitalization in young infants in Canada. While most babies recover, RSV can cause severe breathing problems and place major stress on families and the health system.
- Trial name
- SHIELD-RSV (NCT07693166)
- Testing
- RSVpreF
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Nutrient Intake
Leucine Requirements in School-Age Children
Leucine is an essential amino acid, which serves a special purpose of signaling cell growth in muscle in addition to making up protein.
- Trial name
- NCT07492095
- Testing
- Leucine Intake
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cardiovascular Diseases, End Stage Renal Disease
Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates
The Canadian Australasian Randomized Trial of Screening Kidney Transplant Candidates for Coronary Artery Disease (CARSK) will test the hypothesis that eliminating the regular use of non-invasive screening tests for CAD AFTER…
- Conditions
- Cardiovascular Diseases, End Stage Renal Disease, Kidney Transplantation, Dialysis Related Complication
- Trial name
- CARSK (NCT03674307)
- Testing
- No screening, Regular Screening
- Where
- 22 sites in United States, Canada and 2 more
- Volunteers
- 3,306 people
- Sponsor
- University of British Columbia
Prostate Cancer
Long Acting LHRH Versus Short Acting LHRH in the Treatment of Prostate Cancer
Brachytherapy, or Transperineal implantation of the prostate (TPIP), is a recognized form of treatment for localized cancer of the prostate. TPIP has been used at the British Columbia Cancer Agency (BCCA) since 1998.
- Trial name
- NCT00175383
- Testing
- luteinizing hormone-releasing hormone (LHRH) short acting or long acting
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Dental Anxiety in Children, Pain
Virtual Reality for Pain and Anxiety in Pediatric Dental Treatment
The goal of this clinical trial is to learn whether immersive virtual reality (VR) reduces pain and anxiety in children aged 6-12 years during routine dental procedures.
- Trial name
- NCT07636330
- Testing
- Immersive Virtual Reality Headset, Standard Behaviour Guidance
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Vaginismus
Virtual Reality Exposure for Vaginismus: A Replicated Single-Case Design
Vaginismus is a sexual dysfunction characterized by involuntary tightening of the pelvic floor muscles, preventing vaginal intercourse.
- Trial name
- VIVID 2 (NCT06923306)
- Testing
- Virtual reality exposure
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Type 2 Diabetes
6-Weeks of Blood Flow Restriction Training on Immune Cell Function and Bioenergetics
To conduct a randomized control trial to determine the impact of 6-weeks of blood flow restriction training on immune cell function and bioenergetics in adults living with type 2 diabetes.
- Trial name
- NCT07676305
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Dental Neuralgia, Neuropathic Dental Pain
Neuropathic Dental Pain & DBS
This prospective observational study will evaluate pain outcomes in patients with neuropathic dental pain (Atypical Odontalgia/Phantom Tooth Pain) who undergo directional deep brain stimulation (DBS).
- Trial name
- NCT07671950
- Testing
- Directional Deep Brain Stimulation
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University of British Columbia
Heart Failure With Reduced Ejection Fraction (HFrEF)
Implementation of an Encounter-based Patient Decision Aid for Heart Failure Medications in Heart Function Clinics: the SHARE-HF Pragmatic, Stepped-wedge Trial
The goal of this clinical trial is to learn if a shared decision-making tool called SHARE-HF can help more people with heart failure receive guideline-recommended medications.
- Trial name
- SHARE-HF (NCT07670845)
- Testing
- SHARE-HF decision aid
- Volunteers
- 1,350 people
- Sponsor
- University of British Columbia
Parkinson's Disease (PD), REM Sleep Behavior Disorder
IMPACT 360 for Parkinson's Disease
The IMPACT 360 study will evaluate the effects of a combined intervention of exercise, mindfulness, and nutrition on 8 key indicators of health and the mechanisms that drive these changes.
- Trial name
- NCT07443293
- Testing
- Exercise, Meditation, Diet
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Respiratory Synctial Virus, Asthma Childhood
Infant RSV Immunity Study
Respiratory Syncytial Virus (RSV) is a main global cause of respiratory illness and death in infants. Previous infant vaccine trials have failed to demonstrate protection.
- Trial name
- IRIS (NCT07653347)
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Sepsis
Smart Discharges for Older Children
This study is an observational multi-country cohort study that aims to build algorithms that can identify children between 5 and 16 years of age admitted for proven or suspected sepsis who are at risk of mortality after they are…
- Trial name
- NCT07629154
- Testing
- No Intervention: Observational Cohort
- Where
- 7 sites in United States, Canada and 3 more
- Volunteers
- 4,000 people
- Sponsor
- University of British Columbia