Clinical trials: sponsored by University of Calgary
Catheterization, Peripheral
Peripherally Inserted Central Catheter Insertion Site and Complication Rate in Neonates
This study examines whether there is an association between the PICC insertion site and the complications necessitating PICC removal in neonates admitted to neonatal intensive care unit.
- Trial name
- NCT03474978
- Testing
- Peripherally Inserted Central Venous Cather (PICC)
- Where
- Canada
- Volunteers
- 320 people
- Sponsor
- University of Calgary
Stroke, Acute, Thromboses, Intracranial
Alteplase Compared to Tenecteplase in Patients With Acute Ischemic Stroke
The proposed trial is a pragmatic, registry linked, prospective, randomized (1:1) controlled, open-label parallel group clinical trial with blinded endpoint assessment of 1600 patients to test if intravenous tenecteplase (0.25…
- Trial name
- AcT (NCT03889249)
- Testing
- Tenecteplase, Alteplase
- Where
- 22 sites in Canada
- Volunteers
- 1,600 people
- Sponsor
- University of Calgary
Post Partum Depression
Adaptation and Pilot Testing of Web and Mobile Interface for the VID-KIDS Intervention
COVID-19 has placed unprecedented strains on parents impacted by toxic stress (depression, addiction, intimate partner violence, and poverty) and reluctant to see mental health-service providers in home/clinic due to fears of…
- Trial name
- VID-KIDS (NCT04818047)
- Testing
- VID-KIDS Intervention Program
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Breast Cancer, Colorectal Cancer
The ONE-MIND Study: Evaluating the Efficacy of Online Mindfulness-Based Cancer Recovery During Chemotherapy Treatment
Background: Chemotherapy treatment (CT) can have burdensome side effects such as fatigue, nausea-vomiting, and sleep problems that can significantly affect patients' quality of life.
- Conditions
- Breast Cancer, Colorectal Cancer, Chemotherapy Effect
- Trial name
- NCT03484000
- Testing
- Online Mindfulness Based Cancer Recovery (MBCR)
- Where
- Canada
- Volunteers
- 178 people
- Sponsor
- University of Calgary
Cesarean Delivery
Transversalis Fascia Plane Blocks for Analgesia Post-cesarean Delivery
The aim of this study is to assess the efficacy of a bilateral TFP block in parturients undergoing cesarean delivery (CD) by evaluating postoperative opioid consumption and numeric rated pain scores in two groups (TFP block with…
- Trial name
- NCT03236324
- Testing
- ultrasound-guided nerve block, Saline, Bupivacaine-epinephrine
- Where
- Canada
- Volunteers
- 106 people
- Sponsor
- University of Calgary
Osteoporosis, Age-Related, Osteoporosis Risk
A Culinary Intervention for Bone Health
This is a randomized, controlled pilot study to evaluate the feasibility and acceptability of a single 2-hour culinary medicine intervention for bone health among individuals with age-associated low bone mass.
- Trial name
- NCT05197244
- Testing
- Culinary Medicine Intervention
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Surgery-Complications, Anesthesia Complication
De-implementing Low Value Preoperative Care Wisely
Low value preoperative testing does not improve patient outcomes or reduce adverse events. Low value preoperative testing costs patients and healthcare systems without benefit.
- Trial name
- NCT05566327
- Testing
- De-implementation Bundle
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Healthy
Effect of Prebiotic Intake on Gut Microbiota in Healthy Adults
In recent years, the importance of the gut microbiota to human health has been demonstrated. In adulthood, the microbial profile is relatively stable, yet can be transiently altered by factors such as diet or antibiotic…
- Trial name
- NCT03042494
- Testing
- Control, Prebiotic
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Coronary Artery Disease, Acute Coronary Syndrome
The IMPART Study: The Impact of Patient Education in Cardiac Rehabilitation
Background: Exercise-based cardiac rehabilitation (CR) is the gold-standard in tertiary prevention of coronary artery disease (CAD), yet average CR attendance is only 67%.
- Trial name
- NCT03474185
- Testing
- Taking Charge of your Heart Health patient education classes
- Where
- Canada
- Volunteers
- 103 people
- Sponsor
- University of Calgary
Clostridium Difficile
C Difficile Near-patient Diagnostics
The investigators will conduct a two-period, two-intervention, cluster randomized crossover (CRXO) designed study at Foothills Hospital in Calgary, Alberta.
- Trial name
- NCT03857464
- Testing
- Near Patient Testing, SOP for C. difficile diagnostics
- Where
- 2 sites in Canada
- Volunteers
- 3,816 people
- Sponsor
- University of Calgary
Covid19, Nosocomial Infection
Treatment of Nosocomial COVID-19
COVID-19 is a respiratory disease caused by a novel coronavirus (SARS-CoV-2) and causes substantial morbidity and mortality. Nosocomial acquisition of SARS-CoV-2 is a frequent concern across hospital settings in Canada and is…
- Conditions
- Covid19, Nosocomial Infection, SARS-CoV2 Infection
- Trial name
- CATCO-NOS (NCT04748588)
- Testing
- Anti-SARS-CoV-2 mAb
- Where
- 4 sites in Canada
- Volunteers
- 46 people
- Sponsor
- University of Calgary
Inflammatory Bowel Diseases, Maladaptive Behavior Associated With Physical Illness
TMS in Inflammatory Bowel Disease
Transcranial magnetic stimulation (rTMS) has demonstrated diagnostic and therapeutic potential for a number of conditions and is an approved treatment for depression.
- Trial name
- NCT04956159
- Testing
- iTBS repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Calgary
Treatment Resistant Depression
Accelerated High-dose Sequential Bilateral Theta Burst Stimulation for Treatment Resistant Depression
Repetitive transcranial magnetic stimulation (rTMS) and Theta burst stimulation (TBS) are approved by the US. Food and Drug administration (FDA) for the treatment of refractory major depression.
- Trial name
- NCT05811104
- Testing
- Sequential bilateral theta burst stimulation
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Multiple Sclerosis, Clinically Isolated Syndrome
Minocycline in MS: Confirmation of Benefit
This is an open-label, single-arm clinical trial. Trial participants will include men and women, aged 18-60 years who have had a first demyelinating event within the previous 180 days and who have brain magnetic resonance imaging…
- Trial name
- MS (NCT04291456)
- Testing
- Minocycline 100mg
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- University of Calgary
COVID-19
Improving Adherence to COVID-19 Prevention Behaviours: Test of Persuasive Messages
The goal of this randomized online experiment was to test the effectiveness of using various persuasive appeals (deontological moral frame, empathy, identifiable victim, goal proximity, and reciprocity) at improving intentions to…
- Trial name
- NCT05722106
- Testing
- Persuasive Appeal
- Where
- Canada
- Volunteers
- 3,746 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Cerebral Palsy
Initial Outcomes of Robotic Lower Extremity Exoskeleton Use by a Non-ambulatory Child With CP
There are very few evidence-based interventions for children with cerebral palsy who cannot walk. The Trexo-Home is a device that is newly available for rent by families, but its impact is unknown.
- Trial name
- NCT04251390
- Testing
- trexo Home
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Calgary
Pain, Procedural
Reframing Needle-related Pain
The present research study aims to examine the efficacy of a brief parent-led memory reframing intervention to foster more adaptive (i.e., more accurate and positive) pain memories and less future needle pain and fear for a…
- Trial name
- NCT05217563
- Testing
- Memory-reframing intervention (Reframe the Pain)
- Where
- Canada
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Abdominal Compartment Syndrome, Intra-abdominal Hypertension
Peritoneal Vacuum Therapy to Reduce Inflammatory Response From Abdominal Sepsis/Injury
This pilot study will evaluate the effectiveness in actively removing the peritoneal fluid through the use of a commercial suction device compared to passive drainage of the same peritoneal fluid drained through standard surgical…
- Trial name
- SAD (NCT01355094)
- Testing
- KCI AbThera, "Stampede" VAC
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Calgary
Ventral Hernia
Performance of Biologic Mesh Materials in Abdominal Wall Reconstruction
To date, there have been no prospective randomized controlled trials that compare various biologic mesh materials in the context of abdominal wall reconstruction.
- Trial name
- NCT02703662
- Testing
- Strattice biologic mesh, Permacol biologic mesh
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Calgary
Hemothorax, Thoracic Injuries
The Management of Traumatic Hemothoraces
Chest injuries are common in patients with polytrauma and are responsible for approximate 25% of all trauma-related mortalities. Traumatic injuries to the thorax often result in the accumulation of blood within the chest (i.e.
- Trial name
- HemoTxRCT (NCT03050502)
- Testing
- Chest tube drain, Expectant management
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- University of Calgary