Clinical trials: sponsored by University of Calgary
At Risk of Psychosis
Cognitive Behavioral Social Skills Training for Youth at Risk of Psychosis
Schizophrenia and other psychotic disorders are serious and debilitating mental illnesses that incur substantial suffering for patients and major challenges to the investigators health care and legal systems.
- Trial name
- NCT02234258
- Testing
- Cognitive behavioral social skills, Psychoeducation
- Where
- Canada
- Volunteers
- 203 people
- Sponsor
- University of Calgary
Psychotic Disorders, Depressive Disorder, Major
Adolescent Mental Health: Canadian Psychiatric Risk and Outcome Study
The primary study aims are to determine the clinical, behavioural and social predictors of SMI development in youth, and to investigate whether neuroimaging can distinguish youth who will develop SMI from those who will not.
- Conditions
- Psychotic Disorders, Depressive Disorder, Major, Bipolar Disorder
- Trial name
- PROCAN (NCT02739932)
- Where
- 2 sites in Canada
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Cancer, Psychological
The SEAMLESS Study: Smartphone App-based Mindfulness for Cancer Survivors
Smartphone app-based health interventions are an innovative way to deliver psychosocial cancer-care. In the SEAMLESS study, the investigators aim to evaluate a 4 week smartphone app-based mind-body intervention (MBI) in cancer…
- Trial name
- NCT03557762
- Testing
- Mindfulness
- Where
- Canada
- Volunteers
- 83 people
- Sponsor
- University of Calgary
Sleep Apnea, Obstructive, Renal Insufficiency, Chronic
Treatment of Obstructive Sleep Apnea in Chronic Kidney Disease
This study is being conducted to determine whether treatment of obstructive sleep apnea (OSA) in patients with chronic kidney disease (CKD) improves kidney function.
- Trial name
- NCT02420184
- Testing
- CPAP, No CPAP
- Volunteers
- 57 people
- Sponsor
- University of Calgary
Depression, Psychological Distress
A Pilot Study of the Effect of Personalized Depression Risk Communication
Depression is a highly prevalent and disabling mental health problem. It is associated with significant morbidity and mortality and it has a significant economic impact.
- Trial name
- NCT04519892
- Testing
- PDRC, Coach guidance
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Chronic Kidney Disease
Evaluation of Fructose Ingestion and the Renin Angiotensin System in Humans
Fructose is an ingredient that is added to many of our foods. It is a cheaper, sweeter additive that can be found in everything from soda pop to yogurt to granola bars.
- Trial name
- NCT01407627
- Testing
- Fructose
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of Calgary
Dementia
Going Down Memory Lane: A Technological Intervention
Over 90% of people living with dementia (PLWD) experience behavioural and psychological symptoms of dementia, including apathy, depression, sleep disruptions, wandering, repetitive behaviours and anxiety.
- Trial name
- NCT04131374
- Testing
- Reminiscence Therapy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Lung Cancer, Mesothelioma
Screening of Alberta Asbestos Exposed Workers for Lung Cancer and Mesothelioma
Asbestos defines a group of naturally occurring mineral silicate fibers which are easily inhaled, resulting in a variety of diseases of the respiratory system including lung cancer and malignant mesothelioma.
- Trial name
- NCT02385812
- Testing
- Low-dose computed tomography Annual scan x3, Low-dose computed tomography Baseline scan only
- Where
- 2 sites in Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Validation of Respiratory Rate Monitor Versus Capnography
Validating the Accuracy of a Continuous Respiratory Rate Measurement Device
While respiratory rate is considered a critical vital sign, it often goes unmeasured or is ignored primarily due to shortcomings of the currently used measurement methods.
- Trial name
- NCT04712240
- Testing
- Respiration rate monitor
- Where
- Canada
- Volunteers
- 169 people
- Sponsor
- University of Calgary
Nonunion of Fracture of Scaphoid Bone, Fractures, Ununited
Scaphoid Non-union and Low-intensity Pulsed Ultrasound Trial
This is a prospective, double-blind, multicentered, randomized controlled trial to determine the effectiveness of low-intensity pulsed ultrasound in decreasing the time to union of scaphoid non-unions after operative fixation as…
- Trial name
- SNAPU (NCT02383160)
- Testing
- Bioventus Exogen 4000: Low-intensity pulsed ultrasound
- Where
- 6 sites in Canada
- Volunteers
- 154 people
- Sponsor
- University of Calgary
Multiple Sclerosis, Secondary Progressive
Hydroxychloroquine and Indapamide in SPMS
The purpose of this clinical trial is to determine if HCQ in a dose of 400mg daily and indapamide in a dose of 2.5mg daily can help in reducing the progression of disability in people with secondary progressive multiple…
- Trial name
- NCT05013463
- Testing
- Hydroxychloroquine Pill, Indapamide Pill
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- University of Calgary
Parkinson Disease
Apomorphine Effects on Pain in Parkinson's Disease
To study the effects of acute apomorphine vs. placebo administration on different Parkinson's disease pain types.
- Trial name
- NCT04879134
- Testing
- Apomorphine Injectable Solution
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Complete Tear of Scapholunate Ligament, Scapholunate Dissociation
Evaluation of the Surgical Proficiency and Effectiveness of the Acumed Scapholunate Repair System in Primary Scapholunate Instability Among Canadians
This study is a prospective, multi-centre, non-randomized, and non-blinded follow-up study to assess the efficacy and effectiveness of the ACUMED® Scapholunate Repair System in primary scapholunate interosseous ligament (SLIL)…
- Trial name
- CanRASL (NCT04980547)
- Testing
- ACUMED® Scapholunate Repair System Group
- Volunteers
- 50 people
- Sponsor
- University of Calgary
Chronic Pain, Pelvic Pain
Evaluating the Efficacy of Intranasal Oxytocin Among Individuals With Persistent Pain
This study is a placebo-controlled, double-blind, within-participants crossover investigation of the effect of intranasal oxytocin on pain and function among women with chronic pelvic pain.
- Trial name
- NCT02888574
- Testing
- Intranasal Oxytocin
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Calgary
Chronic Pain, Survivorship
WebMAP for Childhood Cancer Survivors
Background: There are over 500,000 survivors of childhood cancer in North America alone. One in four survivors experiences chronic pain after treatment has completed.
- Conditions
- Chronic Pain, Survivorship, Childhood Cancer
- Trial name
- NCT05241717
- Testing
- Web-based Management of Adolescent Pain (WebMAP)
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- University of Calgary
Patient Compliance
Understanding and Promoting Health Behaviour Change Amid Transition to Cardiac Rehabilitation
The purpose of this study was to test whether a brief motivational intervention is associated with enrollment in cardiac rehabilitation.
- Trial name
- UPBeAT-CR (NCT02721758)
- Testing
- Brief Motivational Intervention
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Calgary
Dystonia Disorder, Parkinson Disease
Botulinum Toxin Type A for Foot Dystonia-associated Pain in Parkinson's Disease
To study the effects of Botulinum toxin type A (BTXA) in the treatment of foot dystonia-associated pain in Parkinson's disease
- Trial name
- NCT04277247
- Testing
- Botulinum toxin type A
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
COVID-19, SARS-CoV-2 Infection
Clinical Characteristics and Outcomes of Pediatric COVID-19
Rationale: The clinical manifestations of SARS-CoV-2 infection in children are poorly characterized. Preliminary findings indicate that they may be atypical.
- Conditions
- COVID-19, SARS-CoV-2 Infection, Pediatric ALL, Pneumonia, Viral
- Trial name
- PERN-COVID-19 (NCT04330261)
- Testing
- Exposure (not intervention) - SARS-CoV-2 infection
- Where
- Canada
- Volunteers
- 10,610 people
- Sponsor
- University of Calgary
Blepharoptosis, Ecchymosis; Eyelid
Fibrin Sealant in Eyelid Surgery
This study is looking at the effect of Tisseel in eyelid surgery. Fibrin sealants (Tisseel) cause there to be less bleeding during surgery. Surgeons have used Tisseel for over two decades to reduce bruising.
- Trial name
- NCT05358977
- Testing
- Tisseel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Yoga, Meditation
Meditation and Yoga for Irritable Bowel Syndrome
Study Aim: This study will explore the feasibility and effectiveness of a yoga program for patients with IBS. Methods: A superiority RCT with 30 participants per group.
- Conditions
- Yoga, Meditation, Irritable Bowel Syndrome
- Trial name
- MY-IBS (NCT04302623)
- Testing
- Yoga
- Where
- Canada
- Volunteers
- 79 people
- Sponsor
- University of Calgary