Clinical trials: sponsored by University of Cincinnati
Intracerebral Hemorrhage
Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH)
The purpose of this study is to find risk factors for hemorrhagic stroke, specifically intracerebral hemorrhage (ICH), among Caucasians, African Americans, and Hispanics.
- Trial name
- ERICH (NCT01202864)
- Where
- 15 sites in United States
- Volunteers
- 6,000 people
- Sponsor
- University of Cincinnati
Cancer
Safety Study of BEZ235 With Everolimus in Subjects With Advanced Solid Tumors
The purpose of this clinical trial is to determine the effects good or bad of combining BEZ235 along with Everolimus to determine if it is a safe treatment for patients with advanced cancers of different types.
- Trial name
- NCT01508104
- Testing
- BEZ235, Everolimus
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Cincinnati
High Grade Glioma
Radiation Planning Study for High Grade Brain Tumors
The purpose of this research study is to see if a higher strength MRI procedure provides better images to use in planning radiation treatments for patients with brain tumors in the future.
- Trial name
- NCT01191346
- Testing
- 3T MRI
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Cincinnati
Binge Eating, Depression
Study of Duloxetine vs Placebo in Treatment of Binge Eating Disorder With Depression
The purpose of this research study is to test the safety of duloxetine and see what effects (good and bad) it has on the subject's binge eating disorder and comorbid depressive disorder (depression occurring with binge eating…
- Trial name
- NCT00607789
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Cincinnati
Sarcoidosis
Use of Immunosuppressive Therapy for Sarcoidosis
Retrospective review of the outcome of use of immunosuppressive drugs in treatment of sarcoidosis
- Trial name
- NCT02356445
- Testing
- Cytotoxic drug
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- University of Cincinnati
Atrial Fibrillation
Recurrent Atrial Fibrillation
This study will evaluate the recurrence rates of atrial fibrillation that develops in the hospital following non cardiac procedures or surgeries or acute medical illnesses.
- Trial name
- Recurrent AF (NCT02898545)
- Testing
- SEEQ monitor
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Cincinnati
Recurrent Major Depressive Disorder With Atypical Features
Pilot Study of Betahistine Dihydrochloride in the Treatment of Major Depression With Atypical Features
The purpose of this study is to determine a dose of the investigational drug betahistine dihydrochloride that is both well tolerated and potentially effective in treating the symptoms of atypical depression.
- Trial name
- NCT00585585
- Testing
- betahistine dihydrochloride
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Cincinnati
Bipolar Depression
Asenapine for Bipolar Depression
The purpose of this study is to compare asenapine with placebo in the treatment of depression associated with bipolar disorder, type I over eight weeks.
- Trial name
- NCT01807741
- Testing
- Asenapine
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Cincinnati
Epilepsy
Equivalence Among Antiepileptic Drug Generic and Brand Products in People With Epilepsy: Single-Dose 6-Period Replicate Design (EQUIGEN Single-Dose Study)
The United States Food and Drug Administration (FDA) has specific rules which generic drug companies must follow to get a generic copy of a seizure medication approved.
- Trial name
- NCT01733394
- Testing
- Lamotrigine Generic "A" Lamotrigine Generic "B" Lamotrigine "Brand", lamotrigine
- Where
- 8 sites in United States
- Volunteers
- 54 people
- Sponsor
- University of Cincinnati
Bipolar Disorder, Alcohol Abuse
Efficacy and Tolerability of Topiramate in Treatment of Bipolar Mania and Alcohol Use in Adolescents and Young Adults
The purpose of this research study is to study the effects (both good and bad) of combining quetiapine and topiramate for treating symptoms of bipolar mania (an illness with periods of elation, excessive excitement, irritability…
- Trial name
- NCT00550394
- Testing
- Quetiapine and Topiramate
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Cincinnati
Stroke
High Intensity Interval Training in Chronic Stroke
The objective of this study was to compare the effectiveness of high intensity interval training (HIT) and traditional aerobic training for persons with stroke.
- Trial name
- HIT (NCT01958606)
- Testing
- High-intensity interval training (HIT), Traditional Aerobic Training
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Cincinnati
Coronary Artery Disease
Anti-gravity Treadmill Exercise in Stress Myocardial Perfusion Imaging
This study will test the hypothesis that the anti-gravity treadmill can be safely used in stress nuclear myocardial perfusion imaging in patients unable to perform conventional treadmill exercise.
- Trial name
- NCT02628002
- Testing
- Antigravity treadmill (Alter-G), Conventional treadmill/regadenoson
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Cincinnati
Cardiac Arrhythmia
Same Day Discharge
This study is to assess if subjects receiving a clinically indicated implanted cardiac pacemaker or defibrillator can be safely discharge home the same day of the procedure.
- Trial name
- NCT02943512
- Testing
- Discharge day of procedure
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Cincinnati
Mild Cognitive Impairment
Energy Metabolism and Cognitive Aging
Participants 60 and older with and without Parkinson's disease who have mild cognitive decline will be randomized to either a standard higher carbohydrate diet or a carbohydrate-restricted ketogenic diet for 8 weeks.
- Trial name
- NCT00777010
- Testing
- Ketogenic diet, Healthy high carbohydrate diet
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Cincinnati
Juvenile Primary Fibromyalgia Syndrome (JPFS), Fibromyalgia
Safety and Efficacy of Fluoxetine in Juvenile Fibromyalgia
The purpose of this research is to conduct an open, pilot trial to assess the efficacy and safety of fluoxetine in the treatment of Juvenile Primary Fibromyalgia Syndrome (JPFS).
- Trial name
- NCT00115804
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Cincinnati
Methamphetamine Dependence, Methamphetamine Abuse
Safety Assessment of Potential Interactions Between IV Methamphetamine and Osmotic-Release Methylphenidate (OROS-MPH)
This is a human inpatient clinical pharmacology study to assess potential interactions between intravenous (i.v.) methamphetamine infusion and oral osmotic release methylphenidate (OROS-MPH).
- Trial name
- NCT00603434
- Testing
- OROS-MPH
- Where
- 2 sites in United States, Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Substance-Related Disorders
Motivational Enhancement Therapy to Improve Treatment Utilization in Pregnant Substance Users - 1
The purpose of this study is to compare Motivational Enhancement Therapy (MET) with standard drug abuse treatment among pregnant women.
- Trial name
- NCT00078143
- Testing
- Behavior Therapy
- Where
- 6 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Cincinnati
Alcohol Drinking, Anxiety Disorders
Retraining Attention to Treat Alcohol Dependence and Social Anxiety
The purpose of this research is to test a computerized intervention for people with co-occurring social anxiety and alcohol dependence.
- Trial name
- AMP (NCT01886716)
- Testing
- Anxiety Attention Training, Alcohol Attention Training, Control Training
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Cincinnati
Acute Decompensated Heart Failure
Assessment of Coronary Flow Reserve in Heart Failure Patients After Ultrafiltration Versus Diuretics
The purpose of this research study is to compare the effects (good and bad) of ultrafiltration treatment with standard intravenous (in your vein) diuretic therapy (furosemide, torsemide, bumetanide) on your heart function and…
- Trial name
- NCT01457053
- Testing
- Loop diuretics (furosemide, torsemide, bumetanide), Ultrafiltration
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- University of Cincinnati
Cognitive Aging
Nutritional Supplementation in Cognitive Aging
To evaluate the effect of supplemented berry fruit juice and whole fruit berry powder on memory performance and brain function in older adults
- Trial name
- NCT00599508
- Testing
- Concord grape juice, blueberry juice, whole fruit blueberry powder
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Cincinnati