Clinical trials: sponsored by University of Copenhagen
Parent-Child Relations, Infant Development
The Playful Learning in Infancy Program
In the Playful Learning in Infancy Program, parents receive research-based educational guidance on playful interactions with their infants aged 0-1 year.
- Trial name
- PLIP (NCT06352229)
- Testing
- Playful Learning in Infancy Program, Postnatal care as usual
- Where
- Denmark
- Volunteers
- 2,327 people
- Sponsor
- University of Copenhagen
First-time Mothers and Their Partners
Understanding Your Baby: A Parallel Group Study of a Universal Parenting Support Program
In Understanding Your Baby first-time parents receive research-based knowledge on how to interpret their infants' socioemotional needs based on their behavior, and how to meet their infants' socioemotional needs in accordance…
- Trial name
- NCT03991416
- Testing
- Understanding Your Baby, Postnatal care as usual
- Where
- Denmark
- Volunteers
- 1,737 people
- Sponsor
- University of Copenhagen
Behavior Problems in Early Childhood
Pedagogues Promoting Positive Parenting in a Home-visiting Program in At-risk Families: A RCT of VIPP-SD
Supportive parenting is a strong predictor of positive outcomes for children, and harsh parenting is a risk factor for child development, especially for the child developing externalizing problems (overactive, oppositional, and…
- Trial name
- NCT04805918
- Testing
- VIPP-SD
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- University of Copenhagen
Anxiety, Anxiety Disorders
A Feasibility Study of Nature-based Health Interventions for People With Mild to Moderate Anxiety, Depression and Stress
Background and aimThe increased burden on mental health both globally and nationally is a serious challenge that requires attention and action from healthcare professionals, politicians, and decision-makers.
- Conditions
- Anxiety, Anxiety Disorders, Depression - Major Depressive Disorder, Depressive Disorder
- Trial name
- NCT06981000
- Testing
- Locally adapted nature-based health intervention
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- University of Copenhagen
Healthy, Emotion Regulation
Testing the Effects of the Caregiver Interaction Profile Training on the Interactive Skills of Daycare Providers
The goal of this clinical trial is to test the Caregiver Interaction Profile (CIP) training program (Helmerhorst et al., 2017) promoting the relational quality between professional caregivers and children in daycare.
- Conditions
- Healthy, Emotion Regulation, Language Development, Interactive Skills Daycare Providers
- Trial name
- CDP (NCT05654116)
- Testing
- Caregiver Interaction Profile (CIP) training
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Non-Alcoholic Fatty Liver Disease, Obesity
Direct Versus Indirect Effect of Amino Acids on Hepatokines
Liver hormones are key metabolic regulators and increased in metabolic diseases, including fatty liver disease. The underlying mechanisms driving the elevated levels are currently unknown and presents a major challenge in…
- Trial name
- Diaakine (NCT06240039)
- Testing
- Evaluating the acute effect of an amino acid infusion with and without a concomitant infusion of the somatostatin analogue octreotide to eliminate endogenous production of glucagon
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Nutritional Status, Micronutrient Status
Health and Nutritional Outcomes Among Young Females and Children in Southwest Bangladesh
This study aims to examine how societal and climate changes influence the nutritional status and fish consumption of young women over a 10 year period in southern Bangladesh, and how these factors affect their children's health.
- Conditions
- Nutritional Status, Micronutrient Status, Omega 3 Fat Status, Diet Diversity
- Trial name
- AQUAFOOD (NCT07541742)
- Testing
- The follow-up aims to evaluate natural changes occurring from adolescence to young adulthood with respect to the study objectives due to lifestyle and environmental factors, without any intervention.
- Where
- Bangladesh
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Nutritional Status, Omega 3 Fat Status
Association of Seafood Consumption and Nutritional Status Among Adolescent Girls
This study examines how seafood consumption, social changes, and climate change affect the nutrition and well-being of adolescent girls in south-western Bangladesh.
- Conditions
- Nutritional Status, Omega 3 Fat Status, Micronutrient Status, Fish Consumption
- Trial name
- AQUAFOOD (NCT07555197)
- Testing
- Assess natural behavior
- Where
- Bangladesh
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Blood Sample, Interference With Routine Analyical Tests
The Acute Interference of Biotin in Blood Analysis
Biotin, also known as vitamin B7, is a water-soluble vitamin. It is essential for several metabolic processes in the body, including glucose, lipid, and protein metabolism, as it acts as a coenzyme in several carboxylation…
- Conditions
- Blood Sample, Interference With Routine Analyical Tests, Biotin Ingestion
- Trial name
- ABBA (NCT07302880)
- Testing
- Overall: To evaluate the acute effect of biotin intake on streptavidin-based laboratory assays during the hours immediately following consumption
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healthy
Identifying Biological Markers for Altitude Exposure and Use of Recombinant Human Erythropoietin (rHuEPO)
The project represents a well powered study of the human response to altitude exposure combined with rHuEPO treatment. A total of 20 male and 20 female non-competing athletes will participate.
- Trial name
- NCT04227665
- Testing
- Sea level, Altitude
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Incretin Effect
The Effect of GIP, GLP-1 and GLP-2 in Individuals With Genetically Altered Receptor Function
This project will characterize the physiological effect of the hormones, GIP-, GLP-1- and GLP-2 infusions in a group of individuals that are carriers of GIP-, GLP-1- and GLP-2 receptor gene variants, respectively.
- Trial name
- H-21044858 (NCT06194955)
- Testing
- GIP(1-42), GLP-1, GLP-2
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Spinal Muscular Atrophy (SMA), Cerebral Palsy (CP)
Gut Peptides and Bone Remodeling in Children With Neuromuscular Disorders
Both GIP and GLP-2 reduce bone resorption (measured as CTX) in healthy adult individuals. In this study, we will investigate whether GIP and GLP-2 reduce CTX in children with spinal muscular atrophy, duchenne muscular dystrophy…
- Conditions
- Spinal Muscular Atrophy (SMA), Cerebral Palsy (CP), Duchenne Muscular Dystrophy (DMD)
- Trial name
- NCT07254988
- Testing
- Meal test, GIP + GLP-2
- Where
- Denmark
- Volunteers
- 3 people
- Sponsor
- University of Copenhagen
Blood Flow
The Role of GIP in Postprandial Splanchnic Blood Flow Distribution and Metabolism in Patients With Type 2 Diabetes
This project will describe the mechanisms of action and the relative contributions of GIP to changes in gastrointestinal blood flow induced by oral glucose and endogenous GIP with the use of a receptor antagonists GIP(3-30)NH2 in…
- Trial name
- GA-17b (NCT06426823)
- Testing
- GIPR antagonist / study tool
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- University of Copenhagen
Postoperative Infections, Mandibular Nerve Injuries
Surgeons' Prediction of Dental Surgery Complications and the Influence of Patient Characteristics: Development of an AI Model
The goal of this observational study is to learn how to better predict and prevent intra- and postoperative complications in oral surgery in adult patients referred for oral surgical procedures.
- Conditions
- Postoperative Infections, Mandibular Nerve Injuries, Alveolar Osteitis, Complication
- Trial name
- NCT07461324
- Where
- 2 sites in Denmark
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healhty, Other: Short-Chain Fatty Acid (SCFA)
Metabolic Effects of Short-Chain Fatty Acids in Healthy Individuals
The primary objective of this study is to investigate the acute physiological and metabolic effects of ingesting the short-chain fatty acids (SCFA)s propionate (three carbon atoms long; C3:0) and butyrate (C4:0) in healthy men…
- Conditions
- Healhty, Other: Short-Chain Fatty Acid (SCFA), Other: Butyrate (C4), Other: Propionate (C3)
- Trial name
- SCFA (NCT07183488)
- Testing
- Propionate followed by Butyrate, Butyrate followed by Propionate
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Stillbirth, Delivery Complication
The PartoMa Project: Enabling Best Post Possible Childbirth Care in Tanzania.
Introduction Childbirth care remains suboptimal in many low-resource settings, causing unacceptable maternal and perinatal mortality and morbidity.
- Conditions
- Stillbirth, Delivery Complication, Delivery Delayed, Apgar; 4-7 at 1 Minute
- Trial name
- NCT04685668
- Testing
- The PartoMa guidelines and training
- Where
- Tanzania
- Volunteers
- 65,181 people
- Sponsor
- University of Copenhagen
Mitochondrial Diseases, Mitochondrial Myopathy
Exercise Training Effects on Muscle Function in Adults With Mitochondrial Myopathy
The goal of this observational study is to learn how exercise training affects molecular processes in skeletal muscle in adults with mitochondrial myopathy, compared with healthy adults.
- Trial name
- MM-EX (NCT07450690)
- Testing
- Unilateral high-intensity interval training (HIIT)
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Multimorbidity
Enhanced Care for Patients With Complex Multimorbidity in Primary Care
Introduction Patients living with a chronic disease often have more than one chronic condition, which is referred to as multimorbidity.
- Trial name
- MM600-DK (NCT05676541)
- Testing
- Complex intervention to enhance care for patients with multimorbidity in general practice consisting of an extended overview consultation and supporting elements
- Where
- Denmark
- Volunteers
- 117,000 people
- Sponsor
- University of Copenhagen
Breastfeeding, Breastfeeding, Exclusive
Breastfeeding - a Good Start Together
The Breastfeeding - a Good Start Together intervention study aims to increase the proportion of women who breastfeed for four and six months, and proportionately more in a group of women who are in risk of early breastfeeding…
- Trial name
- NCT05311631
- Testing
- Breastfeeding support
- Where
- 21 sites in Denmark
- Volunteers
- 5,010 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Childhood Obesity, Childhood Obesity Pevention
School Meals in Denmark
This study looks at how a national school meal program affects the health, well-being, and learning of Danish schoolchildren aged 10 to 15 years.
- Conditions
- Childhood Obesity, Childhood Obesity Pevention, Well-being/Quality of Life, Diet Habits
- Trial name
- NCT07389421
- Testing
- School meal classes
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen