Clinical trials: sponsored by University of Iowa
Breast Neoplasms
Positron Emission Mammography With Fluorothymidine (FLT) to Evaluate Treatment Response to Chemotherapy in Breast Cancer
Positron Emission Tomography Imaging with 3-Deoxy-3'-[18F]Fluorothymidine (FLT) can selectively identify proliferating and non-proliferating tissues, including tumors.
- Trial name
- NCT00934401
- Where
- United States
- Sponsor
- University of Iowa
Neuroblastoma, Neuroendocrine Tumor
90Y DOTA/Retinoic Acid for Neuroblastoma and Neuroendocrine Tumor (NET)
This study is for patients with neuroblastoma or a neuroendocrine tumor who have not been able to have standard therapy or have failed the first-line therapy.
- Trial name
- NCT01048086
- Testing
- Retinoic Acid
- Where
- United States
- Sponsor
- University of Iowa
Knee Osteoarthritis
Mobility Optimization Through Velocity Exercise
Knee Osteoarthritis (OA) accounts for a significant proportion of mobility limitations and is one of the most disabling problems facing the growing population of older adults.
- Trial name
- MOVE (NCT00844558)
- Testing
- Gait Training, Control
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Iowa
Diagnostic Errors
Diagnostic Time-Out: A Randomized Clinical Trial of a Checklist to Improve Diagnostic Accuracy
Diagnostic errors are common, but they have been largely ignored by patient safety groups. Diagnostic errors are often traced to physicians' cognitive biases and failed heuristics (mental shortcuts).
- Trial name
- NCT01868659
- Testing
- Diagnostic checklist, Usual care with no diagnostic checklist
- Volunteers
- 114 people
- Sponsor
- University of Iowa
Eosinophilic Esophagitis (EoE)
Bethanechol for Eosinophilic Esophagitis
The primary goals of this study are to ease the symptoms of patients with Eosinophilic Esophagitis (EoE) and to test the effectiveness of the drug bethanechol in relieving those symptoms.
- Trial name
- NCT02058537
- Testing
- Bethanechol
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Iowa
Knee Osteoarthritis
Assessment of Efficacy of Low Intensity Resistance Training in Men at Risk for Symptomatic Knee Osteoarthritis
The purpose of this research study is to determine whether low intensity resistance training with concurrent application of a peripheral blood flow restriction device to the exercising limb will elicit increased quadriceps…
- Trial name
- PBFR3 (NCT01487525)
- Testing
- Double leg press with partial blood flow restriction, Double leg press without partial blood flow restriction
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Cancer
Interactionality of Music Preference and Individual Variables in Pain Perception and Management
The purposes of this study were 1) to delineate any differences in general musical taste (trait) and context-specific music preference (state), as well as preferred music characteristics in cancer patients, 2) to investigate the…
- Trial name
- NCT02652039
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Iowa
Hypertension
Improving Adherence to Blood Pressure Guidelines
The purpose of this study is to evaluate the impact of physician/pharmacist collaborative teams on hypertension guideline adherence for patients with uncontrolled hypertension in six family medicine practice sites in Iowa.
- Trial name
- NCT00201019
- Testing
- Physician-pharmacist collaborative intervention
- Where
- United States
- Volunteers
- 623 people
- Sponsor
- University of Iowa
Informed Consent
Comprehension of Research Informed Consent When Applied Through a Telemedicine Medium
The investigators hypothesis is that patient comprehension of telemedicine-enabled research informed consent is not inferior to standard face-to-face research informed consent.
- Trial name
- NCT02541799
- Testing
- Audio-visual telemedicine, Standard care
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of Iowa
Dense Deposit Disease
Sulodexide Treatment in Patients With Dense Deposit Disease
The purpose of this study is to see if a medicine called Sulodexide will help prevent or slow down the progression of Membranoproliferative Glomerulonephritis type II/Dense Deposit Disease.
- Trial name
- NCT00583427
- Testing
- Sulodexide
- Where
- United States
- Sponsor
- University of Iowa
The Focus of the Study is to Monitor MRI Signal Changes and Inflammatory Biomarkers With Use of Aspirin in Patients With Unruptured Cerebral Aneurysm
Aspirin Attenuates Inflammation in Human Cerebral Aneurysms
Hypothesis: aspirin attenuates inflammation in cerebral aneurysms and hence reduces the incidence of rupture. This effect can be monitored using the signal generated by macrophages (inflammatory biomarker) in ferumoxytol-enhanced…
- Trial name
- NCT01710072
- Testing
- aspirin
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Chronic Kidney Disease
Behavioral Intervention and Adherence in Dialysis
The aim of the proposed work is to conduct a randomized controlled trial (RCT) evaluation of a behavior change intervention designed to enhance fluid-intake adherence (compliance) among hemodialysis patients.
- Trial name
- NCT01066949
- Testing
- Behavioral self mangement, Support and discussion
- Where
- 2 sites in United States
- Volunteers
- 119 people
- Sponsor
- University of Iowa
Intracranial Neoplasms, Neoplasm Metastasis
Safety Study of 2DG With Stereotactic Radiosurgery
Ionizing radiation produces cancer cell death by creating high levels of reactive oxygen species (ROS), such as superoxide and hydrogen peroxide, in irradiated cells. Cancer cells are preferentially affected by ROS.
- Trial name
- NCT00247403
- Testing
- 2-deoxyglucose (2DG)
- Where
- United States
- Sponsor
- University of Iowa
Angioedema
Study of Heparin Prophylaxis of Hereditary Angioedema Exacerbations
OBJECTIVES: I. Determine the safety and efficacy of inhaled and subcutaneously administered heparin in the treatment of hereditary angioedema.
- Trial name
- NCT00004694
- Testing
- heparin
- Volunteers
- 24 people
- Sponsor
- University of Iowa
Lymphatic Malformations
Study of Picibanil (OK432) Sclerotherapy in Children With Macrocystic Lymphatic Malformations
OBJECTIVES: I. Determine the efficacy of picibanil sclerotherapy in children with macrocystic lymphangioma.
- Trial name
- NCT00010452
- Testing
- picibanil
- Where
- 13 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of Iowa
Efficacy of Ultrasound Guided Nerve Block
Comparison of Two Different Ultrasound Guided Techniques for Saphenous Nerve Block
Saphenous nerve blocks can be technically challenging. Recently described ultrasound techniques have improved the success rate of saphenous nerve blocks, but randomized controlled trials comparing these techniques are lacking.
- Trial name
- NCT02383615
- Testing
- Saphenous nerve block
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Lung Neoplasms, Neoplasm Metastasis
A Study to Test Lung Function After Radiation Therapy
It is known that radiation damages lung tissue. New human studies at University of Iowa show that the radiation damage is not as expected.
- Trial name
- PFS (NCT01039649)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Iowa
Cardiovascular Diseases, Lung Diseases
Expanding the Role of Pharmacists in Treating Persons With Cardiovascular or Lung Diseases
This study will test whether enhanced continuity of pharmacy care that includes increased communication between inpatient and outpatient settings will improve the appropriateness of medication therapy and reduce the number of…
- Trial name
- IowaCOC (NCT00513903)
- Testing
- Minimal intervention, Enhanced Intervention
- Where
- United States
- Volunteers
- 954 people
- Sponsor
- University of Iowa
Depression, Postpartum
Efficacy of Yoga for Postpartum Depression
The aim of this project is to compare the efficacy of an 8-week yoga intervention, relative to a wait-list control (WLC) condition, for improving psychological functioning and health-related quality of life in depressed…
- Trial name
- NCT02213601
- Testing
- Yoga
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Iowa
Hypertension, Asthma
A Collaborative Model to Improve Blood Pressure (BP) Control and Minimize Racial Disparities
The purpose of the study is to determine the degree to which pharmacist-physician collaborative management (PPCM) of hypertension can be adopted and implemented in clinics with geographic and racial diversity and whether patients…
- Trial name
- NCT00935077
- Testing
- PPCM Asthma, 24 Month PPCM BP, 9 Month PPCM BP
- Where
- 28 sites in United States
- Volunteers
- 1,441 people
- Sponsor
- University of Iowa