Clinical trials: sponsored by University of Iowa
Obesity, Peri-implant Inflammation
The Effect of Obesity on Oral Peri-implant Health - A Cross-Sectional Study
In recent years, greater emphasis has been placed on the link between oral and systemic health. Obesity, a growing medical problem worldwide, has been associated with multiple chronic inflammatory diseases such as diabetes…
- Conditions
- Obesity, Peri-implant Inflammation, Peri-implantitis
- Trial name
- NCT01878071
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Hypertension
Team Management of High Blood Pressure
The purpose of this study is to test whether blood pressure control can be improved by physician education and feedback provided through the development of physician/pharmacist collaborative teams.
- Trial name
- NCT00201045
- Testing
- Physician/Pharmacist Collaborative Teams
- Where
- United States
- Volunteers
- 179 people
- Sponsor
- University of Iowa
Cardiovascular Diseases, Coronary Disease
Computed Tomography (CT)--An Epidemiologic Study in the Young
To investigate the relationship between coronary heart disease risk factors and coronary artery calcification in middle age adults from the Muscatine Study.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Atherosclerosis, Heart Diseases
- Trial name
- NCT00005354
- Sponsor
- University of Iowa
Charcot Marie Tooth Disease
Development and Validation of a Disability Severity Index for CMT
It is necessary for outcome measures to accurately reflect the state of health of a person in order for clinical trials to show benefit.
- Trial name
- 6604 (NCT01455623)
- Where
- United States
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Cognition Disorders, Alzheimer Disease
Treatment for Early Memory Loss
The purpose of this study is to evaluate the effectiveness of donepezil (Aricept) for the treatment of mild cognitive impairment (MCI) in elderly adults.
- Trial name
- NCT00042172
- Testing
- Donepezil, Ginkgo Biloba Extract
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Kidney Failure, Chronic
Effect of Exercise on Endothelial Function and Vascular Compliance in Chronic Kidney Disease
The study hypothesis is that 6 weeks of repetitive handgrip exercise will improve endothelial function and venous compliance in pre-dialysis patients with an estimated glomerular filtration rate of less than or equal to 20…
- Trial name
- NCT01068314
- Testing
- Repetitive arm exercise
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Iowa
Sudden Cardiac Death, Arrhythmias
Genetic Risk Assessment of Defibrillator Events
Arrhythmias remain a major health problem, causing at least 250,000 deaths annually in the United States. Pharmacological treatments often do more harm than good, and device therapies are limited by high cost and effects on…
- Conditions
- Sudden Cardiac Death, Arrhythmias, Congestive Heart Failure, Cardiomyopathy
- Trial name
- GRADE (NCT02045043)
- Where
- 6 sites in United States
- Volunteers
- 1,807 people
- Sponsor
- University of Iowa
Breast Neoplasms
Ultrasound Targeting for the Lumpectomy Cavity
Accurate targeting of treatment sites should increase local control by radiation therapy for breast-cancer lumpectomy patients. Currently, ultrasound localization is used for prostate cancer patients to locate the prostate before…
- Trial name
- NCT00583843
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Iowa
Cardiovascular Diseases, Heart Diseases
Arterial Endothelial Function--An Epidemiologic Study
To determine if risk factors measured in childhood can predict the development of atherosclerotic coronary and carotid artery disease in adulthood.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Arteriosclerosis, Carotid Artery Diseases
- Trial name
- NCT00005545
- Volunteers
- 600 people
- Sponsor
- University of Iowa
Depressive Disorder, Depression
Magnetic Stimulation Therapy for Treating Vascular Depression
This 12-week study will evaluate the effectiveness of repetitive transcranial magnetic stimulation (rTMS) of the brain, followed by citalopram (Celexa®), for treatment of depression associated with small vascular lesions in the…
- Trial name
- rtms (NCT00044798)
- Testing
- Repetitive transcranial magnetic stimulation (rTMS), Citalopram
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of Iowa
Depression, Depression, Postpartum
Clinician Managed Interpersonal Psychotherapy
This 12-week study will evaluate the effectiveness of Clinician-Managed Interpersonal Psychotherapy (CM-IPT) in treating postpartum depression and will compare CM-IPT to standard IPT.
- Trial name
- NCT00043602
- Testing
- Standard interpersonal psychotherapy (IPT), Clinician managed interpersonal psychotherapy (CM-IPT)
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Depression, Heart Failure, Congestive
Interpersonal Psychotherapy for Depression in People With Heart Failure
This study will evaluate the effectiveness of interpersonal psychotherapy and behavioral activation techniques in treating depression in people with congestive heart failure.
- Trial name
- NCT00353223
- Testing
- Interpersonal and behavioral psychotherapy, Attention control (AC) condition
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Iowa
Huntington Disease, Chorea
Citalopram to Enhance Cognition in HD
This research plan proposes to conduct a double-blind, placebo-controlled pilot clinical trial in 36 adults with mild Huntington's disease (HD) to address the following research aims: 1.
- Conditions
- Huntington Disease, Chorea, Executive Dysfunction
- Trial name
- CIT-HD (NCT00271596)
- Testing
- 20mg daily citalopram
- Where
- 3 sites in United States
- Volunteers
- 33 people
- Sponsor
- University of Iowa
Fibrosis
Trental & Vitamin E for Radiation-Induced Fibrosis
This study seeks to determine if a combination of Trental and Vitamin E prevents the development of radiation fibrosis in women treated with radiation for the definitive management of their breast cancer.
- Trial name
- NCT00583700
- Testing
- Pentoxifylline, Vitamin E
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Iowa
Stroke
Extending Acute Stroke Trials to the Aerial Inter-hospital Transfer Setting
We are inviting patients who have been diagnosed with an ischemic or hemorrhagic stroke and are being transferred by Air Care helicopters to the University of Iowa Hospitals and Clinics (UIHC) for further care to participate in…
- Trial name
- AIRDOC (NCT00585351)
- Testing
- Ranitidine, Advanced notification, No advanced notification
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Iowa
Huntington Disease, Chorea
Atomoxetine and Huntington's Disease
The purpose of this research study is to evaluate the effect of atomoxetine (also known as Strattera) compared to placebo (inactive substance) on daily activities such as attention and focus, thinking ability and muscle movements…
- Trial name
- NCT00368849
- Testing
- atomoxetine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Iowa
COPD
Trial of Non-invasive Ventilation for Stable COPD
The use of domiciliary non-invasive positive pressure ventilation (NPPV) in stable chronic obstructive pulmonary disease (COPD) with chronic hypercapnic respiratory failure has yielded variable effects on survival, quality of…
- Trial name
- NCT01722773
- Testing
- Bipap (Respironics, Inc)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Iowa
Bullous Pemphigoid
Efficacy and Safety of Omalizumab in Bullous Pemphigoid
The primary objective is to test the safety and efficacy of Xolair in the treatment of the autoimmune blistering disease, bullous pemphigoid (BP). This is a pilot, open label case-control study.
- Trial name
- NCT00472030
- Testing
- Omalizumab, prednisone
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Iowa
Spinal Diseases, Other Biomechanical Lesions of Cervical Region
Cervical Spine Biomechanics During Endotracheal Intubation
Current methods for endotracheal intubation in the presence of cervical spine (c-spine) instability are not evidence-based. This is so because the relationships between the forces applied during intubation (by the laryngoscope)…
- Conditions
- Spinal Diseases, Other Biomechanical Lesions of Cervical Region, Tracheal Intubation Morbidity
- Trial name
- NCT01369381
- Testing
- Endotracheal intubation
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Iowa
Chest Pain, Gastrointestinal Reflux Disease
Dexilant Treatment in Gastrointestinal Reflux Disease (GERD Related Non Cardiac Chest Pain
The purpose of this study is to investigate a new treatment for non-cardiac chest pain (NCCP) related to gastrointestinal reflux disease (GERD), called Dexilant.
- Trial name
- Dexilant (NCT01637571)
- Testing
- Dexilant
- Where
- United States
- Sponsor
- University of Iowa