Clinical trials: sponsored by University of Iowa
Cigarette Smoking
The Effectiveness of Smoking Cessation Guidelines in the Emergency Department
Although 78% of smokers report that a health professional has previously advised them to quit smoking, most smokers are not advised to stop smoking or offered assistance with smoking cessation during a given ED visit.
- Trial name
- NCT00756704
- Testing
- Smoking cessation guideline implementation
- Where
- 2 sites in United States
- Volunteers
- 789 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Hearing Impairment
Effectiveness of Hearing-aid Based Wind-noise Algorithm
Wind-noise is highly disturbing to hearing impaired individuals wearing hearing aids who wish to participate in outdoor conversations where wind is present or during activities such as walking or running.
- Trial name
- NCT00738244
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Self-efficacy
Motivational Interviewing Intervention for Intimate Partner Violence
This project is a randomized trial to determine if motivational interviewing (MI) is an effective intervention to help women in abusive intimate relationships.
- Trial name
- ISIS (NCT01410669)
- Testing
- Motivational interviewing (MI)
- Where
- United States
- Volunteers
- 305 people
- Sponsor
- University of Iowa
Tinnitus
Randomized Trial Of Tinnitus Retraining Therapy
Millions of Americans suffer from tinnitus. However, there is no widely accepted treatment that has been shown to be effective in controlled investigations.
- Trial name
- NCT00578058
- Testing
- Counseling and Sound Therapy
- Where
- 4 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of Iowa
Knee Osteoarthritis, Symptomatic Knee Osteoarthritis
Low Intensity Resistance Training With Partial Blood Flow Restriction for Quadriceps Strengthening
The objective of the proposed research is to assess the efficacy of an eight-week, efficient and tolerable, low-intensity resistance-training program with concurrent application of partial blood flow restriction (PBFR) for…
- Trial name
- PBFR (NCT01311206)
- Testing
- partial blood flow restriction, Low intensity exercise without partial blood flow restriction
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Knee Osteoarthritis
TENS Effectiveness and Knee Osteoarthritis in Humans
TENS is a non pharmacological intervention to control pain. Both high (>50 Hz) and low (<10 Hz) frequency TENS are used in the clinic and it is thought that each type works through different mechanisms (see for review Sluka and…
- Trial name
- TOPS (NCT01354054)
- Testing
- High Frequency TENS, Low frequency TENS
- Where
- 3 sites in United States, Brazil and 1 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Knee Osteoarthritis
Platform Exercise Training
The purpose of this randomized, controlled trial is to determine whether a vibration platform exercise program will be more effective than a standard platform exercise program in improving quadriceps strength in women age 45-60…
- Trial name
- NCT01239823
- Testing
- Whole Body Vibration Training, Exercise without vibration
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Motor Vehicle Occupant Injury, Teenaged Driver
Parent-based Intervention to Increase Safe Teen Driving
We hypothesize that this intervention will increase the quality and quantity of parental interaction on safety driving with newly-licensed teen drivers.
- Trial name
- NCT01014923
- Testing
- Teen driving intervention
- Where
- 2 sites in United States
- Volunteers
- 163 people
- Sponsor
- University of Iowa
Constipation
Investigation of Dried Plums in the Treatment of Adults With Constipation
Background: Constipation is a common problem that affects nearly 60 million Americans. The treatment of constipation remains challenging with one half of patients dissatisfied with current therapy.
- Trial name
- NCT01180725
- Testing
- Dried Plum, Metamucil
- Where
- United States
- Sponsor
- University of Iowa
Knee Osteoarthritis
Aquatic Power Training
Knee Osteoarthritis (OA) accounts for a significant proportion of mobility limitations and is one of the most disabling problems facing the growing population of older adults.
- Trial name
- NCT00904319
- Testing
- Aquatic Power Training
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- University of Iowa
Central Venous Pressure
Central Venous Pressure (CVP) Assessment by Ultrasound and Physical Examination
Ultrasound may be useful for noninvasively determining the central venous pressure. We intend to compare the clinical examination of the neck veins; ultrasound delineation of the internal jugular vein; and the central venous…
- Trial name
- NCT01099241
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Iowa
Macular Degeneration
Treatment of Patients With Age-Related Macular Degeneration With Anecortave Acetate
The purpose of this study is to evaluate whether anecortave acetate can slow or stop the progression of age-related macular degeneration in patients who do not qualify for other studies and have no other treatment options.
- Trial name
- NCT00349739
- Testing
- Anecortave Acetate
- Where
- United States
- Sponsor
- University of Iowa
Breast Neoplasm
Yoga to Reduce Cancer Fatigue
A randomized trial from the British National Health Service found that supervised exercise benefits women with early stage breast cancer with improved functional and psychological benefit after a 12-week intervention and 6 months…
- Trial name
- NCT00583739
- Testing
- Yoga
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Iowa
Cancer
Determination of Amifostine Levels During Radiation Therapy
Currently, there are no published methods for easily determining the level of amifostine in the blood or saliva. A method has been developed within the Department of Radiation Oncology by Drs.
- Trial name
- NCT00286611
- Testing
- Blood and salivary sampling of amifostine
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Iowa
Head and Neck Cancer
Study to Calculate the Radiation Dosimetry in Subjects With Head and Neck Cancer
Preliminary observations suggest positron emission tomography (PET) imaging with an F-18 labeled thymidine analog (FLT) can selectively identify proliferating and non-proliferating tissues, including tumors.
- Trial name
- NCT00245349
- Testing
- F-18 Fluorothymidine
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Iowa
Major Depression
Essential Fatty Acids for Major Depression
This is a research study to determine whether omega-3 fatty acid supplementation, when taken with the antidepressant medication escitalopram (Lexapro), helps to improve depressive symptoms in individuals who have major depressive…
- Trial name
- NCT00256412
- Testing
- Eicosapentaenoic acid (EPA) 0.7 grams/day or 1.5 grams/day
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Iowa
Medial Compartment Knee Osteoarthritis
Study of How An Ankle Strap Changes Effects of Insole Treatment for Knee Osteoarthritis
The goal of this project is to assess the effects of an ankle strap on the effectiveness of a laterally-wedged insole with ankle strapping in reducing knee symptoms and improving static and dynamic lower limb biomechanics.
- Trial name
- NCT00331110
- Testing
- Laterally-Wedged Insole with Ankle Strapping, Laterally-Weged Insole
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Iowa
Infant, Premature, Anemia
Liberal Versus Restrictive Transfusion Guidelines for Preterm Infants
The purpose of this study was to determine whether restrictive guidelines for red blood cell (RBC) transfusions for preterm infants can reduce the number of transfusions without adverse consequences.
- Conditions
- Infant, Premature, Anemia, Intracranial Hemorrhages, Leukomalacia, Periventricular
- Trial name
- NCT00369005
- Testing
- Red blood cell transfusion guidelines
- Volunteers
- 100 people
- Sponsor
- University of Iowa