Clinical trials: sponsored by University of Malaya
Walking Mesh
Smart Sock for Monitoring Walking and Supporting Physical Activity in Older Adults
The goal of this randomized feasibility clinical trial is to learn whether a low-cost smart sock and mobile application can be used safely, reliably, and comfortably to support gradual walking activity in adults aged 60 years and…
- Trial name
- NCT07902102
- Testing
- Low-Cost Smart Sock and Older-Adult Mobile Application, Standard Individual Walking Plan
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Oral Health-Related Quality of Life
Manus AI-Assisted Orthodontic Education and Oral Health-Related Quality of Life
The goal of this clinical trial is to learn whether adding artificial intelligence (AI)-assisted education to standard orthodontic education can improve quality of life in adults starting treatment with fixed braces.
- Trial name
- NCT07832604
- Testing
- Conventional Orthodontic Education, Manus AI-Assisted Orthodontic Education
- Volunteers
- 230 people
- Sponsor
- University of Malaya
Type 2 Diabetes Mellitus (DM)
Tolerability and Safety of Nano-Tocotrienols
The goal of this randomised controlled trial is to determine the long term safety and tolerability of nano-tocotrienols (50 - 400 mg/day for 6-months duration) to be used as a health supplement in both healthy individuals and…
- Trial name
- NCT07888426
- Testing
- Nano-tocotrienols
- Where
- Malaysia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Tuberculosis (TB)
Pharmacist-led Digital Interventions to Improve Tuberculosis Treatment Adherence
The gold standard for tuberculosis (TB) treatment support requires directly observed therapy (DOT), which means a trained health worker observes the patient swallow each dose of medication every day for 2 months.
- Trial name
- CARE-TB (NCT07069387)
- Testing
- CARE-TB digital adherence package, Standard Care
- Where
- Malaysia
- Volunteers
- 81 people
- Sponsor
- University of Malaya
Low Level Laser Therapy, Temporomandibular Joint Disorders
The Efficacy of Low-level Laser Therapy (LLLT) as an Adjunct Treatment for Pain and Functional Outcomes in Temporomandibular Disorders (TMD)
The goal of this clinical trial is to evaluate the effectiveness of low-level laser therapy (LLLT) as an adjunct treatment in patients aged 18 years and older diagnosed with temporomandibular disorders (TMD).
- Conditions
- Low Level Laser Therapy, Temporomandibular Joint Disorders, Pain, Physical Therapy
- Trial name
- LLLT IN TMD (NCT07840495)
- Testing
- LLLT
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Wisdom Tooth, Socket Preservation
Application of Alloplastic Bone Graft With Polycaprolactone (PCL) Membrane and ECM-Collagen Membrane on Secondary Socket Healing in Third Molar Surgery.
This study compared two membrane materials: 1. polycaprolactone (PCL) and 2. Extracellular matrix collagen membrane (ECM) as alternative. This is to see how well they prevent bone and gum damage after lower wisdom tooth removal.
- Trial name
- PCL ECM (NCT07834645)
- Testing
- polycarprolactone membrane (PCL membrane), Extracellular matrix collagen (ECM) membrane
- Where
- Malaysia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Critical Illness
The Effect of High Protein and Early Resistance Exercise Versus Usual Care in Critically Ill Patients
This is a 2-arm, parallel-group, randomized controlled trial that investigates the effect of combined high protein and early resistance exercise versus usual care on muscle mass, quality and strength, clinical outcomes…
- Trial name
- EFFORT-X (NCT04261543)
- Testing
- High protein and early exercise, Usual Care
- Where
- Malaysia
- Volunteers
- 51 people
- Sponsor
- University of Malaya
Perioperative Anxiety
Individualized Music Versus Propofol for Perioperative Anxiety During Regional Anaesthesia
Perioperative anxiety is common among patients undergoing surgery under regional anaesthesia. Intravenous sedative-hypnotic agents such as propofol are commonly administered to reduce anxiety and improve patient comfort; however…
- Trial name
- NCT07820787
- Testing
- Professionally Prescribed Individualized Music, propofol
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- University of Malaya
Critical Illness, Covid19
Body Composition Study in Critically Ill Patients-Extended to COVID-19
Muscle loss (ultrasound quadricep muscle) and muscle strength (handgrip and knee extension strength) will be compared between COVID-19 and non COVID-19 critically ill patients.
- Conditions
- Critical Illness, Covid19, Muscle Atrophy, Muscle Strength
- Trial name
- COVID-MUSCLE (NCT04849624)
- Testing
- No Intervention
- Where
- Malaysia
- Volunteers
- 59 people
- Sponsor
- University of Malaya
Temporomandibular Disorders, Chronic Pain
Effectiveness of Brief Mindfulness-Based Interventions for Painful Temporomandibular Disorders Among University Students
The goal of this clinical trial is to learn if brief mindfulness-based intervention (BMBI) is beneficial to participants suffering from painful temporomandibular disorders (TMD). The objectives of the research are: 1.
- Trial name
- NCT06582134
- Testing
- BMBI
- Where
- Malaysia
- Volunteers
- 127 people
- Sponsor
- University of Malaya
Dentine Caries
Effectiveness of Single and Dual Silver Fluoride Application
This is a community-based, parallel-group, double-blinded randomised controlled trial aimed at evaluating the effectiveness of single and dual applications of 38% Silver Fluoride (SF) in arresting dentinal caries among Malaysian…
- Trial name
- NCT07658690
- Testing
- 38% Silver Fluoride (Riva Star Aqua)
- Where
- Malaysia
- Volunteers
- 148 people
- Sponsor
- University of Malaya
Anemia
NeoSpHb Study: Can a Painless Device Detect Anaemia in Babies Without Blood Tests? A Study in the Neonatal Intensive Care Unit (NICU)
The goal of this study is to evaluate the diagnostic performance and feasibility of non-invasive spectrophotometric haemoglobin (SpHb) measurement for detecting anaemia in infants admitted to the Neonatal Intensive Care Unit…
- Trial name
- NeoSpHb (NCT07788703)
- Testing
- Spectrophotometry hemoglobin
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- University of Malaya
Obstructive Sleep Apnea
CES-EES Clinical Score and a Wearable Ring Sensor for Obstructive Sleep Apnea: Individual and Combined Validation Against In-Laboratory Polysomnography
This study evaluates whether a clinical upper airway assessment tool (the Clinical Examination Score plus ENT Examination Score, CES-EES) and an artificial-intelligence wearable ring (Belun Ring, Belun Sleep System BLS-100) can…
- Trial name
- NCT07785999
- Testing
- Belun Ring (Belun Sleep System BLS-100), CES-EES Clinical Scoring
- Where
- Malaysia
- Volunteers
- 58 people
- Sponsor
- University of Malaya
Adolescent Idiopathic Scoliosis
Preoperative Carbohydrate Drink in Adolescent Idiopathic Scoliosis Surgery: the Impact on Safety and Enhanced Recovery
The goal of this interventional study is to learn if carbohydrates loading improves overall outcome in adolescent patient undergoing scoliosis curgery The main questions of the study are as follows: 1.
- Trial name
- CARBO-AIS (NCT06680297)
- Testing
- Carbohydrates loading, Control group
- Where
- 2 sites in Malaysia
- Volunteers
- 60 people
- Sponsor
- University of Malaya
Dental Anxiety, Behavioral Management
Effect of Dental Anxiety Management by Integrative Music-mindfulness Intervention Among Iraqi Adult Patients in a Karbala City Private Clinic, an RCT Study
Dental anxiety considered as one of the weariest problems and disturbing problems with which the individual dentist has had to fight.
- Trial name
- NCT05844878
- Testing
- Distraction technique by using music therapy., Mindfulness technique by using of relaxation breathing with muscle relaxation
- Where
- 2 sites in Iraq, Malaysia
- Volunteers
- 288 people
- Sponsor
- University of Malaya
Postoperative Nausea and Vomiting, Scoliosis
A Comparison Between Palonosetron Versus Granisetron as PONV Prophylaxis in Scoliotic Patients Undergoing Spine Surgery
The aim of this clinical trial is to compare the effectiveness of two Serotonin (5- HT3) receptor antagonist, palonosetron and granisetron, administered along with dexamethasone as a preventive measure against early and delayed…
- Trial name
- PONV (NCT06540885)
- Testing
- Palonosetron (Group P), Granisetron (Group G)
- Where
- 2 sites in Malaysia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Stroke, Attention
Enhancing Attention and Processing Speed Through Home-based Music Rehabilitation Program After Stroke in Malaysia
Stroke often leads to significant cognitive impairment, impacting quality of life. While existing rehabilitation options exist, there's a need for innovative, accessible, and patient-centered solutions.
- Conditions
- Stroke, Attention, Rehabilitation Program, Music Intervention
- Trial name
- HMRPAS (NCT07522463)
- Testing
- Musical Home-based Rehabilitation Program, Control group (standard care)
- Where
- Malaysia
- Volunteers
- 44 people
- Sponsor
- University of Malaya
Compassion Fatigue
Evaluating the Effectiveness of the Moving to Emptiness Technique in Reducing Counsellors' Compassion Fatigue
The goal of this clinical trial is to learn if Moving to Emptiness Technique (MET) works to treat counselors' compassion fatigue (CF).
- Trial name
- NCT07718035
- Testing
- Moving to Emptiness Technique (MET)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya
OSA - Obstructive Sleep Apnea, Palatal Expansion Technique
Miniscrew-Assisted Rapid Palatal Expansion for Obstructive Sleep Apnea
The goal of this clinical trial is to learn whether miniscrew-assisted rapid palatal expansion (MARPE) can improve obstructive sleep apnea (OSA) in late adolescents and adults aged 16 to 60 years.
- Trial name
- NCT07734688
- Testing
- Miniscrew-Assisted Rapid Palatal Expansion, Standard Care (in control arm)
- Volunteers
- 24 people
- Sponsor
- University of Malaya
Wisdom Tooth, Socket Preservation
Soft and Hard Tissue Healing Following Alveolar Ridge Preservation of Mandibular Third Molar Extraction Socket Filled With Auto Tooth Bone Graft or Alloplastic Graft
This study compared two bone graft materials: 1. Auto Tooth Bone (ATB) (made from the patient's own extracted tooth) and 2. EthOss® a synthetic alternative.
- Trial name
- AutoToothGraft (NCT07723183)
- Testing
- auto tooth graft material
- Where
- Malaysia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Malaya