Clinical trials: sponsored by University of Malaya
Supraglottic Airways for General Anesthesia
Study of Accuracy of Placement and Performance Test in Detecting Supraglottic Airway Placement Compared to Fiberoptic View. Recruited Patients in University Malaya Medical Center, Malaysia, Undergoing General Anesthesia With Supraglottic Airway.
The goal of this cross sectional observational study is to compare the accuracy of placement and performance tests to gold standard method of fiberscope assisted insertion of Supraglottic Airway(SGA) Device for optimal SGA…
- Trial name
- NCT07726472
- Testing
- fiberoptic view of glottis
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Orthodontic Retention
The Effect of Full Versus Partial Coverage Thermoformed Retainers in Dual Retention With a Lower Bonded Retainer, on Periodontal, Orthodontic, and Patient-Reported Outcomes
After braces are removed, teeth may move back toward their original positions. Retainers are used to help keep teeth straight after orthodontic treatment.
- Trial name
- NCT07669129
- Testing
- Partial coverage vivera retainer, Full coverage Vivera retainer
- Where
- Malaysia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Bimaxillary Proclination, Bimaxillary Protrusion
Survival, Success, Stability, and Patient Comfort of TADs Placed by Steady Oblique-Angled Versus Two-Step Angulation Insertion Techniques
The goal of this clinical trial is to learn if two-step angulation Temporary Anchorage Devices (TADs) insertion technique better for survival, stability and patient-reported outcomes.
- Trial name
- NCT07715851
- Testing
- Temporary Anchorage Device (TAD), Two-step Angulation with Partial Unwinding Technique
- Where
- Malaysia
- Volunteers
- 28 people
- Sponsor
- University of Malaya
Dementia
Exploratory Evaluation of Staff-Mediated Doll Therapy in Chinese Residential Dementia Care: A Mixed-Methods Cluster Randomized Pilot Trial
This study is a two-phase explanatory sequential mixed-methods study in Chinese residential dementia care. Phase I is a pragmatic 1:1 exploratory pilot cluster randomized trial in six nursing homes in Zhengzhou, China, comparing…
- Trial name
- NCT06506487
- Testing
- Doll Therapy
- Where
- China
- Volunteers
- 142 people
- Sponsor
- University of Malaya
Dental Erosion, Erosive Tooth Wear
Quantitative In Vivo Monitoring of Early Erosion-Associated Enamel Optical Changes Using Swept-Source Optical Coherence Tomography.
This study aims to evaluate the ability of swept-source optical coherence tomography (SS-OCT) to detect early enamel optical changes associated with erosive tooth wear under clinically relevant in vivo conditions.
- Trial name
- NCT07690644
- Testing
- Swept-Source Optical Coherence Tomography (SS-OCT), Orange Juice Erosive Challenge, Sugar-Free Chewing Gum Stimulation
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Depressive Disorder, Anxiety
Adjunctive Resonance-Based Chinese Five-Element Music Intervention for Depressive Disorders and Anxiety Symptoms in Male Inpatients
This randomized controlled trial will evaluate the effectiveness of Resonance-Based Chinese Five-Element Music Intervention (RFEMI) as an adjunct to pharmacotherapy in male inpatients with depressive disorders.
- Conditions
- Depressive Disorder, Anxiety, Randomised Controlled Trial
- Trial name
- RCFMI (NCT07653113)
- Testing
- Resonance-Based Chinese Five-Element Music Intervention(RFEMI) plus pharmacotherapy group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- University of Malaya
Diaper Dermatitis
Breast Milk Versus Barrier Creams for Diaper Dermatitis in Children Aged 0-24 Months
Diaper dermatitis is a common inflammatory skin condition among children aged 0-24 months. Although commercial barrier creams are widely used, maternal breast milk has been suggested as a safe, accessible, and low-cost…
- Trial name
- NURSE-DD (NCT07633808)
- Testing
- Topical Maternal Breast Milk, Commercial Barrier Cream
- Where
- Palestinian Territories
- Volunteers
- 160 people
- Sponsor
- University of Malaya
Osteoarthritis (OA) of the Knee
Evaluating the Effectiveness of Mobithron Xtra in Patients With Primary Knee Osteoarthritis Over a 3-month Period
Knee osteoarthritis is a common condition that causes knee pain, stiffness, reduced mobility, and difficulty performing daily activities.
- Trial name
- NCT07643662
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- University of Malaya
Coronary Arterial Disease (CAD), Myocardial Infarction (MI)
The Impact of Audiovisual Structured Patient Education Material in Improving Clinical and Behavioural Outcomes in Home-Based Cardiac Rehabilitation Programme Participants
The goal of this clinical trial is to find out if newly developed, culturally adapted educational videos-sent through a mobile messaging app-can help people with coronary heart disease do better in a home-based cardiac…
- Conditions
- Coronary Arterial Disease (CAD), Myocardial Infarction (MI), Ischemic Heart Disease (IHD), Cardiac Rehabilitation
- Trial name
- NCT07636460
- Testing
- Audiovisual Structured Patient Education Materials, Standard Educational Materials
- Where
- Malaysia
- Volunteers
- 21 people
- Sponsor
- University of Malaya
Non Small Cell Lung Carcinoma NSCLC
Impact of Chemotherapy Dose Reductions on Survival Outcomes Among Older NSCLC Patients Without Actionable Mutations
Evidence suggests that appropriately selected older adults can tolerate standard-dose chemotherapy and achieve survival outcomes comparable to younger patients.
- Trial name
- NCT07369596
- Testing
- Progression free survival, Overall survival
- Where
- 4 sites in Hong Kong, Malaysia
- Volunteers
- 150 people
- Sponsor
- University of Malaya
Postoperative Pain, Postoperative Pain Management
Evaluating the Efficacy and Utility of the Automated Pupillometer in Pain Assessment and Opioid Administration Guidance During the Perioperative Period: A Randomized Controlled Trial
Effective intraoperative and postoperative pain management is critical for patient comfort and recovery, yet traditional methods for assessing pain under general anaesthesia are limited by their subjective nature and reliance on…
- Trial name
- NCT07614607
- Testing
- Opioid Analgesic, automated pupillometry
- Where
- Malaysia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Dietary Diversity
Dietary Diversity of Young Children During CoVID-19 Outbreak: A Longitudinal Study
The 2019-2020 coronavirus pandemic has had far-reaching consequences beyond the spread of the disease. Quarantine measures during a public health pandemic can be particularly detrimental to urban poor families and affect the…
- Trial name
- CoDDYC (NCT04447209)
- Testing
- 2-weekly Food baskets
- Where
- Malaysia
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Airway Management
Channelled Blade Versus Non-Channelled Videolaryngoscope
The goal of this clinical trial is to learn if performance of a channelled blade Astra-Vue videolaryngoscope compared to non channelled hyperangulated C-MAC D-blade videolaryngoscope(Karl Storz, Tuttlingen, Germany) in airway…
- Trial name
- NCT07577648
- Testing
- channelled blade videolaryngoscope, Non channelled hyperangulated blade videolaryngoscope
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Dental Anxiety
Impact of Dental Anxiety Coping Module on Children With Dental Anxiety
The aim of this study is to evaluate the impact of the Dental Anxiety Coping Module (DACM) in children with dental anxiety. The main questions to answer are: 1.
- Trial name
- NCT06483828
- Testing
- Dental Anxiety Coping Module
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Hyperkalemia
Lower vs. Standard Insulin-Dextrose Doses for Treating Mild to Moderate Hyperkalemia in the Emergency Department
This clinical trial aims to evaluate the safety and efficacy of a lower dose insulin compared to the conventional dose for treating mild to moderate hyperkalemia, a condition characterized by elevated serum potassium levels below…
- Trial name
- IDK+ (NCT06724991)
- Testing
- Lower Dose Therapy, Conventional Dose Therapy
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- University of Malaya
Rehabilitation, Cognition
Intensive Music Therapy on Cognitive Function in Subacute Stroke Rehabilitation in Malaysia
The purpose of this study is to explore whether intensive music therapy can help improve cognitive functions like memory, attention, and decision-making skills in stroke patients who are undergoing rehabilitation.
- Conditions
- Rehabilitation, Cognition, Stroke, Attention
- Trial name
- NCT06763003
- Testing
- Music Therapy, Standard Care (in control arm)
- Volunteers
- 36 people
- Sponsor
- University of Malaya
Fall Prevention
Pilot Feasibility Study of a Fall Prevention Exercise Programme for Community-dwelling Older Adults in Nanchang, China
The goal of this pilot clinical trial is to evaluate the feasibility of a fall prevention exercise programme for older adults living in urban communities in China.
- Trial name
- NCT07341802
- Testing
- Safe & Joyful Walk, Tai Chi
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
Hybrid Exercise Program for Heart Disease: Effect on Health and Quality of Life
Cardiac rehabilitation (CR) participation remains suboptimal, partly due to logistical challenges and limited access to center-based programs.
- Trial name
- NCT07130045
- Testing
- Hybrid Endurance Strength Training, Usual Care
- Where
- Malaysia
- Volunteers
- 84 people
- Sponsor
- University of Malaya
Periodontitis
Probiotics as Adjunctive Therapy in the Management of Periodontitis
The goal of this clinical trials is to learn about the effect of taking Prodentis on a long term basis following periodontal therapy. The main question it aims to answer is 1.
- Trial name
- NCT07531875
- Testing
- Prodentis
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- University of Malaya
CLABSI - Central Line Associated Bloodstream Infection
Efficacy & Cost Effectiveness of Antimicrobial-impregnated CVCs in CLABSI Prevention in a Malaysia Adult ICU
Central venous catheters (CVCs) are indispensable in modern critical care. However, CVC usage is associated with complications, including central line-associated bloodstream infections (CLABSIs), which in turn, is translated to…
- Trial name
- NCT05959018
- Testing
- Arrow Three-Lumen Central Venous Catheter, Arrowg+ard Blue Plus® Three-Lumen Central Venous Catheter
- Where
- Malaysia
- Volunteers
- 110 people
- Sponsor
- University of Malaya